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CLL Support

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Cordyceps

Hi all. I wanted to share this site I found of a guy who got his counts fully down by drinking cordyceps tea every day. I’m about to start it....

Hi all. I wanted to share this site I found of a guy who got his counts fully do...

RedPandaLS

•27 days ago

20 Replies

Does cognitive decline accelerate in older adults after diagnosis with CLL compared with the cognitive trajectory seen in normal aging?

Some welcome reassuring news! In this cohort study, 668 older adults with hematologic malignant neoplasms and 1994 matched participants without...

Some welcome reassuring news! In this cohort study, 668 older adults with hema...

AussieNeil

Administrator•1 month ago

12 Replies

Masks and respirators for prevention of respiratory infections: a state of the science review. Conclusion - respirators (N95/FFP2) work best

Note the relative greater protection of respirators (filtering face pieces), over medical masks and community masks per the attached image. Importantly, the...

Note the relative greater protection of respirators (filtering face pieces), ove...

AussieNeil

Administrator•2 months ago

7 Replies

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Real-world treatment switching and sequencing to next line of therapy of zanubrutinib, acalabrutinib, and ibrutinib in CLL/SLL

Acalabrutinib (Calquence) and zanubrutinib (Brukinsa) have been found to be much better tolerated than than ibrutinib, with lower adverse event and side effect...

Acalabrutinib (Calquence) and zanubrutinib (Brukinsa) have been found to be much...

AussieNeil

Administrator•2 months ago

2 Replies

"Accelerated" chronic lymphocytic leukemia/small lymphocytic lymphoma: unraveling CLL/SLL biological gray zone in the era of novel therapies

Encouraging news in this abstract from CLL/SLL researchers at the Northwestern Memorial Hospital, Northwestern University Feinberg School of Medicine, Chicago,...

Encouraging news in this abstract from CLL/SLL researchers at the Northwestern M...

AussieNeil

Administrator•2 months ago

10 Replies

Measurable residual disease (MRD) status predicts Progression Free Survival (PFS) for patients with Chronic Lymphocytic Leukemia (CLL)

Measurable residual disease (MRD) refers to the presence of disease at low levels not detected by conventional pathologic analysis. The association of MRD...

Measurable residual disease (MRD) refers to the presence of disease at low level...

AussieNeil

Administrator•3 months ago

24 Replies

Median PFS for FCR treated CLL patients with IGHV-M was 14.6 years vs 4.2 years for patients with IGHV-UM. V+O and I+R look to be superior

An update of the long-term follow-up results from the original 300-patient FCR (fludarabine, cyclophosphamide, and rituximab) study initiated at MD Anderson in...

An update of the long-term follow-up results from the original 300-patient FCR (...

AussieNeil

Administrator•4 months ago

24 Replies

Just 5% of therapies tested in animals end up as as human drugs, new study shows. CLL research has particular challenges due to the TME

There's a long and challenging journey from microscope observations of cancer cells hopefully dying while exposed to candidate therapies, that is, 'in vitro'...

There's a long and challenging journey from microscope observations of cancer ce...

AussieNeil

Administrator•5 months ago

9 Replies

Leukemia-associated macrophages, their role in the CLL Tumor Micro-environment and how they affect progression and therapy response

Understanding how the CLL Tumor Micro-environment (TME) functions is crucial to improving CLL therapy. CLL cells are not as robust as healthy B cells and they...

Understanding how the CLL Tumor Micro-environment (TME) functions is crucial to ...

AussieNeil

Administrator•6 months ago

7 Replies

People with high blood levels of niacin, (vitamin B3), may be more likely to have a heart attack or stroke than those with lower levels

I have a confession to make: I take vitamin supplements. Why is this a confession? Well, because research has indicated for years that dietary supplements...

I have a confession to make: I take vitamin supplements. Why is this a confessio...

AussieNeil

Administrator•9 months ago

9 Replies

Canadian SCIG and IVIG study

Many us have what is called Secondary Antibody Deficiency. It can be diagnosed via low Total IgG (ImmunoGlobulin G), and often low IgA and IgM, too, as well...

Many us have what is called Secondary Antibody Deficiency. It can be diagnosed v...

SeymourB

•1 year ago

16 Replies

Relative risk for secondary bone marrow cancer within 5 years after initial CLL chemoimmunotherapy treatment (typically BR or FCR)

In countries where targeted therapies ('brutinibs, venetoclax, obinutuzumab/rituximab) are now available, the remaining reason that FCR...

In countries where targeted therapies ('brutinibs, venetoclax, obinutuzumab/ritu...

AussieNeil

Administrator•1 year ago

25 Replies

Further evidence that even moderate exercise is good for your long term health - particularly when you have CLL!

I've often observed that our immediate response when we are diagnosed with CLL, is to re-evaluate our diet (good) and look at how we can extend our time before...

I've often observed that our immediate response when we are diagnosed with CLL, ...

AussieNeil

Administrator•1 year ago

27 Replies

Calquence / acalabrutinib and Brukinsa / zanubrutinib Adverse Event Comparison for Chronic Lymphocytic Leukaemia / CLL from clinical trials

Now that we have a growing choice of BTK inhibitor treatment options, naturally the question is which one is better? Based on this meta-analysis study of the...

Now that we have a growing choice of BTK inhibitor treatment options, naturally ...

AussieNeil

Administrator•1 year ago

4 Replies

UK herbal remedy ingredient check by UCL School of Pharmacy: Many poor quality products, though those with the THR label fare better

Do herbal supplements contain what they say on the label?...

AussieNeil

Administrator•2 years ago

27 Replies

Research shows blood cancer patients generate strong T cell immunity after SARS-CoV-2 vaccination

Today, the Doherty Institute in Melbourne, Australia, released a statement about a research study that shows that blood cancer patients highly benefit from...

Today, the Doherty Institute in Melbourne, Australia, released a statement about...

CLLerinOz

Administrator•2 years ago

22 Replies

Fungal infections cause 3 x the number of deaths caused by malaria... really!? This 9min podcast explains.

"More or Less" Do fungi kill three times as many people as malaria? https://www.bbc.co.uk/sounds/play/w3ct3k63?partner=uk.co.bbc&origin=share-mobile...

"More or Less" Do fungi kill three times as many people as malaria? https://www...

JigFettler

Volunteer•2 years ago

4 Replies

Recent research report

one section of a recent research report covered CLL and it included several topics including the favorable results of vitamin D. Now I can’t find the...

one section of a recent research report covered CLL and it included several topi...

BobTerry62

•2 years ago

2 Replies

Teenager Leukaemia free after a world-first use of sophisticated cell engineering.

A 13-year-old girl who relapsed with a particular type of blood cancer is now leukaemia-free after a world-first use of what scientists have described as the...

A 13-year-old girl who relapsed with a particular type of blood cancer is now le...

Juliette02

•2 years ago

1 Reply

Miracles of science and hope for us

https://www.bbc.com/news/health-63859184 Per Juliette02's introduction, with an alternative report: Teenager Leukaemia free after a...

https://www.bbc.com/news/health-63859184 Per Juliette02's introduction, with a...

nuji

•2 years ago

17 Replies

Fine-Tuning the Wave of Innovation in CLL

ASH2022 is happening in New Orleans, right now. Yesterday, there was a great webinar hosted on the PeerView platform that covered Personalized Models for...

ASH2022 is happening in New Orleans, right now. Yesterday, there was a great w...

SeymourB

•2 years ago

5 Replies

Off patent drug possibility for Covid. Ursodeoxycholic acid (UDCA), an approved liver disease drug, reduces ACE2 levels on lab-grown cells

There seems to be a deal of excitement in certain media areas about research involving UK, European and US researchers on a covid treatment drug. The one in...

There seems to be a deal of excitement in certain media areas about research inv...

Eucalyptus22

•2 years ago

1 Reply

Mexican sarsaparilla ( Smilax aristolochiifolia) for anaemia, CLL

Has anyone heard about this herb for anemia or blood cancer

Family2017

•2 years ago

5 Replies

The failing effectiveness of COVID-19 monoclonal antibodies against BA.1, BA.4-5, BA.4.6, BA.2.75, BJ.1 and BQ.1.1

This post is in response to a couple of recent posts highlighting concerning changes in the effectiveness of our monoclonal antibody armament against new...

This post is in response to a couple of recent posts highlighting concerning cha...

AussieNeil

Administrator•2 years ago

11 Replies

Cardiotoxicity in patients treated with acalabrutinib

The latest edition of the journal Blood has two articles that highlight the issue of cardiotoxicity in patients treated with acalabrutinib. The cardiotoxicity...

The latest edition of the journal Blood has two articles that highlight the issu...

CLLerinOz

Administrator•2 years ago

43 Replies

Survival Outcome Observation

An interesting publication offer relative to recent survival outcome data provided by CLL Society from ASCO 2022 -...

An interesting publication offer relative to recent survival outcome data provid...

Smakwater

•2 years ago

7 Replies

A class of targeted protein degraders offers a possible strategy to overcome BTK inhibitor resistance in chronic lymphocytic leukemia

A research article published in the journal Blood this week reports on a possible way forward for those with CLL who develop BTK inhibitor resistance...

A research article published in the journal Blood this week reports on a possibl...

CLLerinOz

Administrator•2 years ago

2 Replies

Breakthrough in laboratory production of red blood cells towards saving lives of those with Chronic Lymphocytic Leukaemia in the future

One of the triggers for starting treatment for CLL is haemoglobin dropping below 100. The most common use of donated blood is transfusions for those undergoing...

One of the triggers for starting treatment for CLL is haemoglobin dropping below...

AussieNeil

Administrator•2 years ago

5 Replies

Chronic Lymphocytic Leukemia patient survey points to a need for better patient education

The interim report of an ongoing survey of CLL patients demonstrates that over 60% of respondents were unaware of different CLL risk groups and that about 20%...

The interim report of an ongoing survey of CLL patients demonstrates that over 6...

CLLerinOz

Administrator•2 years ago

12 Replies

Prebiotics, probiotics and now postbiotics. What they are and how can they improve our gut health?

Postbiotics are essentially the by-products of our gut microbiota. In other words, your body produces postbiotics after digesting prebiotic and probiotic...

Postbiotics are essentially the by-products of our gut microbiota. In other word...

AussieNeil

Administrator•2 years ago

10 Replies

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Posts - CLL Support | HealthUnlocked

CLL Support

Research news posts

Cordyceps

Does cognitive decline accelerate in older adults after diagnosis with CLL compared with the cognitive trajectory seen in normal aging?

Masks and respirators for prevention of respiratory infections: a state of the science review. Conclusion - respirators (N95/FFP2) work best

Real-world treatment switching and sequencing to next line of therapy of zanubrutinib, acalabrutinib, and ibrutinib in CLL/SLL

"Accelerated" chronic lymphocytic leukemia/small lymphocytic lymphoma: unraveling CLL/SLL biological gray zone in the era of novel therapies

Measurable residual disease (MRD) status predicts Progression Free Survival (PFS) for patients with Chronic Lymphocytic Leukemia (CLL)

Median PFS for FCR treated CLL patients with IGHV-M was 14.6 years vs 4.2 years for patients with IGHV-UM. V+O and I+R look to be superior

Just 5% of therapies tested in animals end up as as human drugs, new study shows. CLL research has particular challenges due to the TME

Leukemia-associated macrophages, their role in the CLL Tumor Micro-environment and how they affect progression and therapy response

People with high blood levels of niacin, (vitamin B3), may be more likely to have a heart attack or stroke than those with lower levels

Canadian SCIG and IVIG study

Relative risk for secondary bone marrow cancer within 5 years after initial CLL chemoimmunotherapy treatment (typically BR or FCR)

Further evidence that even moderate exercise is good for your long term health - particularly when you have CLL!

Calquence / acalabrutinib and Brukinsa / zanubrutinib Adverse Event Comparison for Chronic Lymphocytic Leukaemia / CLL from clinical trials

UK herbal remedy ingredient check by UCL School of Pharmacy: Many poor quality products, though those with the THR label fare better

Research shows blood cancer patients generate strong T cell immunity after SARS-CoV-2 vaccination

Fungal infections cause 3 x the number of deaths caused by malaria... really!? This 9min podcast explains.

Recent research report

Teenager Leukaemia free after a world-first use of sophisticated cell engineering.

Miracles of science and hope for us

Fine-Tuning the Wave of Innovation in CLL

Off patent drug possibility for Covid. Ursodeoxycholic acid (UDCA), an approved liver disease drug, reduces ACE2 levels on lab-grown cells

Mexican sarsaparilla ( Smilax aristolochiifolia) for anaemia, CLL

The failing effectiveness of COVID-19 monoclonal antibodies against BA.1, BA.4-5, BA.4.6, BA.2.75, BJ.1 and BQ.1.1

Cardiotoxicity in patients treated with acalabrutinib

Survival Outcome Observation

A class of targeted protein degraders offers a possible strategy to overcome BTK inhibitor resistance in chronic lymphocytic leukemia

Breakthrough in laboratory production of red blood cells towards saving lives of those with Chronic Lymphocytic Leukaemia in the future

Chronic Lymphocytic Leukemia patient survey points to a need for better patient education

Prebiotics, probiotics and now postbiotics. What they are and how can they improve our gut health?

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