Posts - Advanced Prostate Cancer | HealthUnlocked

Advanced Prostate Cancer

21,427 members • 26,837 posts

All posts for April 2022

Serotonin Makes Tumors Happy Too

Serotonin or 5-hydroxytryptamine (5-HT) is a neurotransmitter primarily found in the gastrointestinal tract (GI tract), blood platelets, and the central...

Serotonin or 5-hydroxytryptamine (5-HT) is a neurotransmitter primarily found in...

Hidden

•2 years ago

1 Reply

GPM6B Inhibit PCa Proliferation by Blocking Prostate Cancer Cell Serotonin Absorptive Capacity

Prostate cancer is currently one of the most common fatal tumor types in men. Although multiple treatments can alleviate some cases, advanced prostate cancer,...

Prostate cancer is currently one of the most common fatal tumor types in men. Al...

Hidden

•2 years ago

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Borrowing Trouble

Yesterday was my husband's quarterly doctor's appointment. He's been in a clinical trial for the last 5 1/2 year. As we near the end of the EMBARK Trial, I...

Yesterday was my husband's quarterly doctor's appointment. He's been in a clinic...

COG1

•2 years ago

20 Replies

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Lupron failing

4 years ago diagnosed with metastatic prostate cancer. 4 years of just Lupron which has now started to fail because 2 months ago PSA .19 and now 3.1. Waiting...

4 years ago diagnosed with metastatic prostate cancer. 4 years of just Lupron w...

GolferDan

•2 years ago

40 Replies

ARASENS: Darolutamide + ADT + Docetaxel may become new SOC for mHSPC - from ASCO GU Symposium 2022

Dr. Matthew R Smith of Mass Gen. CC, reported significant overall survival from 3 ARASENS trial results when compared to placebo + ADT + Docetaxel. A 32%...

Dr. Matthew R Smith of Mass Gen. CC, reported significant overall survival from ...

JRPnSD

•2 years ago

6 Replies

ALT (SGPT) - 5X normal limits - Concerning? Mets to liver lungs and bones

Hello everyone, Just want to give an update on my dad (69) has mets to the bones, liver, lungs and pelvic lymph nodes, PSA 113, Gleason 4+5 upon diagnosis back...

Hello everyone, Just want to give an update on my dad (69) has mets to the bones...

dch1953

•2 years ago

3 Replies

Life expectancy shock revelation

I was considering retiring in June when I am 55 this year. I have a financial advisor who indicated that to give me the best guidance he would need an...

I was considering retiring in June when I am 55 this year. I have a financial ad...

konichiwa12

•2 years ago

47 Replies

The combination of cabazitaxel and cyproheptadine is a promising candidate for overcoming prostate cancer

Prediction of Synergistic Drug Combinations for Prostate Cancer by Transcriptomic and Network Characteristics Prostate cancer (PRAD) is a major cause of...

Prediction of Synergistic Drug Combinations for Prostate Cancer by Transcriptomi...

Hidden

•2 years ago

9 Replies

Prostrate Oncologist Near Chattanooga, TN

I have a very good-natured oncologist near me, but he admits he is a general oncologist and when I discuss many of the treatments and new drugs that are...

I have a very good-natured oncologist near me, but he admits he is a general onc...

Quick2019

•2 years ago

5 Replies

Neoadjuvant ADT - is a slowing PSA drop rate normal?

Hi all, first time poster here. My father (61, very healthy) was DX'd Sept 2021 with high-risk locally advanced prostate cancer with the following profile: G9,...

Hi all, first time poster here. My father (61, very healthy) was DX'd Sept 2021 ...

sixmongoos

•2 years ago

6 Replies

Low PSA levels are associated with greater prostate cancer-specific mortality among men with a Gleason score of 8 to 10

Conclusions: Among patients with high-grade disease, patients with PSA levels ≤ 2.5 ng/mL or PSA levels of 2.6 to 4 ng/mL appear to have a higher risk for...

Conclusions: Among patients with high-grade disease, patients with PSA levels ≤ ...

Hidden

•2 years ago

15 Replies

Combating Fatigue??

My husband is on Lupron/Casodex. He goes to gym 3 times per week for weight lifting plus Pickleball. He rides his bicycle 3-5 times per week about 15 miles. He...

My husband is on Lupron/Casodex. He goes to gym 3 times per week for weight lift...

JolleySprings

•2 years ago

25 Replies

Doctors suggest new names for low-grade prostate cancer.

I'm not sure what I think of this Doctors suggest new names for low-grade prostate cancer....

I'm not sure what I think of this Doctors suggest new names for low-grade prost...

cesces

•2 years ago

12 Replies

Supra-pubic catheter experience

My 78-yo husband has suffered from radiation cystitis/urethretitis. Two years of off & on Foley & self cathing & still no full continence regained. Will...

My 78-yo husband has suffered from radiation cystitis/urethretitis. Two years o...

Lyubov

•2 years ago

11 Replies

Suggestions for keeping urine collection bag from slipping down leg

My 78-yo husband has to return to using Foley external catheter & bag, likely permanently, and is asking those with experience for suggestions to keep the leg...

My 78-yo husband has to return to using Foley external catheter & bag, likely pe...

Lyubov

•2 years ago

38 Replies

Any benefits from a Choline C-11 Scan in addition to Pylarify PSMA PET MRI?

Hi all, Hope your week's off to a strong start. Anyone have a view on whether a C-11 scan will be useful in addition to a PSMA PET? My recurrent PSA is low...

Hi all, Hope your week's off to a strong start. Anyone have a view on whether a ...

PGDuan

•2 years ago

12 Replies

Tinnitus

I've been on Lupron, Zytiga and Prednisone for five months since diagnosis six months ago. Been doing excellent, with no side effects that I know of. Last...

I've been on Lupron, Zytiga and Prednisone for five months since diagnosis six m...

Hidden

•2 years ago

13 Replies

Staying Alive

I heard back from City of Hope that I have strong PSCA expression, and I'm moving forward with the CAR-T trial. I thought I'd share this video clip from the...

I heard back from City of Hope that I have strong PSCA expression, and I'm movin...

Javelin18

•2 years ago

29 Replies

Estradiol =11.9 pg/mL ... 11.0 - 52.5 pg/mL normal range

Estradoil is on low side of normal. thoughts?

Scout4answers

•2 years ago

12 Replies

PSA blip

Hi Everyone, It’s been awhile and DC has been doing great and his PSA has been coming down nicely. He’s on Lupron-3, Zytiga & Prednisone. He got his blood...

Hi Everyone, It’s been awhile and DC has been doing great and his PSA has been c...

jcoil

•2 years ago

4 Replies

Is there any reason my MO will not Rx estradiol patches for hot flashes and bone density?

6 months into Orgovyx , Zytiga and prednisone and I finally watched Snuffy Meyers’ YouTube recommending them .

6 months into Orgovyx , Zytiga and prednisone and I finally watched Snuffy Meyer...

PBnative

•2 years ago

33 Replies

ADT collagen/cartilage issues

Taking a pole I’m in my 4th year of ADT (eligard/Zytiga) and my joints are weaker..most Achilles issues. now both my eyes are affected..vitriol membrane humour...

Taking a pole I’m in my 4th year of ADT (eligard/Zytiga) and my joints are weake...

Jbooml

•2 years ago

15 Replies

Post SRT Testosterone Help

Just had another round of blood tests. First, and most importantly, PSA dropped to 0.02 (Ulta Lab test lowest limit, but not >0.02) from 0.06 at 6-month...

Just had another round of blood tests. First, and most importantly, PSA dropped ...

Teufelshunde

•2 years ago

30 Replies

Lu-177 cycles

Anyone here have more than 4 cycles of Lu-177? Interested in standard protocol because it is so new. Unsure if it can be repeated after bone marrow tests....

Anyone here have more than 4 cycles of Lu-177? Interested in standard protocol ...

Leader4077

•2 years ago

15 Replies

Long distance bicycle riding causes PSA to increase in men aged 50 years and over

Conclusions: Cycling causes an average 9.5% increase in tPSA, in healthy male cyclists ≥50 years old, when measured within 5 minutes post cycling. We...

Conclusions: Cycling causes an average 9.5% increase in tPSA, in healthy male cy...

Hidden

•2 years ago

7 Replies

What is next?

I wrote recently about hitting my sternum and being concerned that it had broken a easily suggesting osteoporosis. The pain got pretty bad especially when...

I wrote recently about hitting my sternum and being concerned that it had broken...

spencoid2

•2 years ago

17 Replies

Where to buy affordable Enzalutamide?

Just wondering if its possible to buy this drug anywhere at reasonable prices? I know I can get generic abiraterone from India which can be affordable. Only...

Just wondering if its possible to buy this drug anywhere at reasonable prices? I...

Howmuchisthefish

•2 years ago

28 Replies

Rice University professor waits on FDA to approve what she hopes will be a cure for prostate cancer

I went to Dr. @ Houston Memorial Hermann to see about this treatment (or one similar upon hearing about it (gold nanoparticles with radiation beads or...

I went to Dr. @ Houston Memorial Hermann to see about this treatment (or one si...

George71

•2 years ago

18 Replies

Glycyrrhizin in licorice root is a novel pharmacological inhibition of HMGB1 that repress prostate cancer metastasis

High mobility group box 1 (HMGB1) is upregulated in nearly every tumor type. Importantly, clinical evidence also proposed that HMGB1 is particularly increased...

High mobility group box 1 (HMGB1) is upregulated in nearly every tumor type. Imp...

Hidden

•2 years ago

5 Replies

Natural metformin alternatives

I know that some of you take metformin. I read that it comes from a natural ingredient called French lilac, also known as Goat's Rue. It is in other plants as...

I know that some of you take metformin. I read that it comes from a natural ingr...

dhccpa

•2 years ago

11 Replies

Posts - Advanced Prostate Cancer | HealthUnlocked

Advanced Prostate Cancer

All posts for April 2022

Serotonin Makes Tumors Happy Too

GPM6B Inhibit PCa Proliferation by Blocking Prostate Cancer Cell Serotonin Absorptive Capacity

Borrowing Trouble

Lupron failing

ARASENS: Darolutamide + ADT + Docetaxel may become new SOC for mHSPC - from ASCO GU Symposium 2022

ALT (SGPT) - 5X normal limits - Concerning? Mets to liver lungs and bones

Life expectancy shock revelation

The combination of cabazitaxel and cyproheptadine is a promising candidate for overcoming prostate cancer

Prostrate Oncologist Near Chattanooga, TN

Neoadjuvant ADT - is a slowing PSA drop rate normal?

Low PSA levels are associated with greater prostate cancer-specific mortality among men with a Gleason score of 8 to 10

Combating Fatigue??

Doctors suggest new names for low-grade prostate cancer.

Supra-pubic catheter experience

Suggestions for keeping urine collection bag from slipping down leg

Any benefits from a Choline C-11 Scan in addition to Pylarify PSMA PET MRI?

Tinnitus

Staying Alive

Estradiol =11.9 pg/mL ... 11.0 - 52.5 pg/mL normal range

PSA blip

Is there any reason my MO will not Rx estradiol patches for hot flashes and bone density?

ADT collagen/cartilage issues

Post SRT Testosterone Help

Lu-177 cycles

Long distance bicycle riding causes PSA to increase in men aged 50 years and over

What is next?

Where to buy affordable Enzalutamide?

Rice University professor waits on FDA to approve what she hopes will be a cure for prostate cancer

Glycyrrhizin in licorice root is a novel pharmacological inhibition of HMGB1 that repress prostate cancer metastasis

Natural metformin alternatives

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