Natural metformin alternatives

[dhccpa]

I know that some of you take metformin. I read that it comes from a natural ingredient called French lilac, also known as Goat's Rue. It is in other plants as well.

Has anyone taken any of those natural forms instead of metformin?

Thanks.

[6357axbz]

Why would you want to do that? The retrospective studies which indicate metformin MAY have a benefit, nothing proven, used the manufactured drug metformin.

[dhccpa in reply to 6357axbz]

I'm just inquiring about it. I haven't made any decision to use it.

[Hidden in reply to 6357axbz]

Why would you, answer a valid question like that? Way to shut someone down.. is exactly what all of us do not need right now.

[6357axbz in reply to Hidden]

Not at all. My point is the evidence that taking metformin has a benefit for us (I take 1000 mg a day) is thin, based on retrospective studies only. Taking some sub-ingredient would be even further removed from any kind of evidence of benefiting mPCa. I was asking dhccps what his logic would be for taking French lilac? Perhaps I’m missing something…

[dhccpa in reply to 6357axbz]

I didn't take offense. Rather, I was simply asking a question. I wasn't recommending that anybody do anything. Perhaps you read more into my question than I intended. It was a simple inquiry.

[pjoshea13]

French lilac & Goat's Rue are non-specific, but both are terms used for Galega officinalis, which does not itself contain Metformin (but was the starting point.)

Metformin was discovered during the synthesis of N,N-dimethylguanidine, so it's a stretch to consider it a natural product, or expect it to be present in nature.

Many drugs have their origin in plants, of course, and what could be more natural than Taxotere (lol). The taxane drug family are diterpenoids derived from the yew [Taxaceae]. Paclitaxel [Taxol] was actually extracted from the Pacific yew.

-Patrick

[dhccpa in reply to pjoshea13]

Thanks. Some of the descriptions I've read confused me on that point.

[dhccpa]

Thanks Nal. I do take Berberine.

[Heilung18-Gesund in reply to dhccpa]

In terms of pathways, like metformin or berberine, resveratrol also activates AMPK and inhibits mTOR.

[Hidden]

Metformin exposure in the previous year may increase the risk for prostate cancer, but exposure in the previous 2 to 7 years may lower the risk, according to a recent study.

cancertherapyadvisor.com/ho...

Metformin can cause lactic acidosis.

ncbi.nlm.nih.gov/pmc/articl...

[dhccpa in reply to Hidden]

I've never taken metformin.