Posts - Advanced Prostate Cancer | HealthUnlocked

Advanced Prostate Cancer

21,390 members • 26,764 posts

All posts for June 2024

some news: new phase 0 trial for new radioligand gives good results

since I am in the waiting room waiting for my PET scan, I am making use of the time ”Unlike PSMA-targeted agents that are accompanied by an uptake in the...

since I am in the waiting room waiting for my PET scan, I am making use of the t...

Maxone73

•4 hours ago

1 Reply

Phase 1b: FOR46, a novel antibody-drug conjugate targeting a tumor-specific epitope of CD46, in combination with Enza in patients with mCRPC

"Preliminary anti-tumor activity was observed with PSA declines in 13/16 (81.3%) of evaluable pts, and a disease control rate (stable disease ≥ 6 months) of...

"Preliminary anti-tumor activity was observed with PSA declines in 13/16 (81.3%)...

Maxone73

•17 hours ago

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proof of concept CUPID trial finished, moving to 1b/2

"The RADmAb® approach accelerates blood clearance and reduces bone marrow residence time compared with standard monoclonal antibodies (mAbs), while retaining...

"The RADmAb® approach accelerates blood clearance and reduces bone marrow reside...

Maxone73

•17 hours ago

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Does this sound right? Any advice appreciated.

My dad, 82 yo male had a previous PSA score that hovered around 3 and then went up to 5. Had MRI/CT which came up clear last year and a prostate biopsy (11...

My dad, 82 yo male had a previous PSA score that hovered around 3 and then went ...

Biddity

•17 hours ago

17 Replies

Interesting concept: More effective cancer treatment with iontronic pump

like the drop that carves the rock.... https://www.eurekalert.org/news-releases/1048606

like the drop that carves the rock.... https://www.eurekalert.org/news-releases...

Maxone73

•18 hours ago

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Lupron SEs - legs

Appreciate this forum and all whom post. I’m amidst 2-year course of Lupron and experiencing persistent leg pain, worst in both Achilles tendons and calves....

Appreciate this forum and all whom post. I’m amidst 2-year course of Lupron and ...

NickKnick

•19 hours ago

8 Replies

Overcoming Pneumonia Susceptibility

I flunked my first docetaxel infusion in late 2022 and a week later developed pneumonia resulting in me carried by ambulance to the hospital. As I said in my...

I flunked my first docetaxel infusion in late 2022 and a week later developed p...

TuffNuttoCrack

•21 hours ago

2 Replies

Chemo Stopped working what's next? T Cell Therapy?

To Believe it I have been told once the chemo stops working the next step is the T Cell Therapy have you done any research on this talk to your doc and see if...

To Believe it I have been told once the chemo stops working the next step is the...

Praying2BHealthy

•23 hours ago

1 Reply

Castrate Resistant

I know that patients who were started at beginning with combo of, say, Lupron plus abiraterone acetate are declared castrate resistant when PSA rises in...

I know that patients who were started at beginning with combo of, say, Lupron pl...

dhccpa

•1 day ago

20 Replies

DO YOU TRUST YOUR DOCTOR : Free registration at https://malecare.org/trust-in-healthcare

Malecare and Prostate Cancer Research (UK) Virtual Conference: TRUST AND HEALTHCARE WEDNESDAY, JUNE 26, 2024 on Youtube.com/Malecare 12 PM ET to 6:10 PM ET...

Malecare and Prostate Cancer Research (UK) Virtual Conference: TRUST AND HEALTH...

Darryl

Partner•1 day ago

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Phase 1: CBP-1018 interesting because it targets bone metastasis as well!

I will keep an eye on this (I am running out of eyes!) preliminary results look promising...

I will keep an eye on this (I am running out of eyes!) preliminary results look...

Maxone73

•1 day ago

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Phase 2 trial: Evaluation of Treatment Interruption After Response in mHSPC

"Patients are allowed to enrolle if they have a stable or falling prostate-specific antigen (PSA) level below 0.2 ng/mL and a castrate testosterone level under...

"Patients are allowed to enrolle if they have a stable or falling prostate-speci...

Maxone73

•1 day ago

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I might have discovered a hidden gem: Clinical Investigators Provide Perspectives on the Current and Future Management of Prostate Cancer

Very interesting, especially because there are big names talking from their direct experiences as practitioners......

Very interesting, especially because there are big names talking from their dire...

Maxone73

•1 day ago

6 Replies

Radioligand Therapy May Improve Radiographic Progression–Free Survival in Taxane-Naive Patients With Advanced Prostate Cancer

Too late for me...but it looks like Pluvicto (and I think radio ligands in general) is moving up in the ladder to reach the first line treatment option...

Too late for me...but it looks like Pluvicto (and I think radio ligands in gener...

Maxone73

•1 day ago

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Should I do chemotherapy?

New here. I am 81 and was diagnosed last month with PCa metastatic to a few bones. Gleason 9. PSA 21 at diagnosis. Have been put on orgovyx and...

New here. I am 81 and was diagnosed last month with PCa metastatic to a few bo...

Simpson80

•1 day ago

5 Replies

pathology report

my dad got his pathology report following prostatectomy what does this all mean doesn’t look confirming

my dad got his pathology report following prostatectomy what does this all mean ...

Chepina23

•2 days ago

23 Replies

Just a quick question.

Hi everyone and thanks for all your help so far. As the chemo has now stopped working for Martin we are looking for any other options that might be available...

Hi everyone and thanks for all your help so far. As the chemo has now stopped ...

Believeit

•2 days ago

6 Replies

When to Commence ADT and/or Androgen Blocking Therapy?

Greetings All - New to this forum but have followed the Healing Well PC forum since beginning treatment in 2018 and later began to follow Prostate Cancer...

Greetings All - New to this forum but have followed the Healing Well PC forum ...

Biochem

•2 days ago

4 Replies

CC260 selective PI5P4Kα and PI5P4Kβ inhibitor

Hii I was going through some article regarding prostate cancer and found that some CC260 , a drug that attacks PI5P4Kα is under research . Many cases of...

Hii I was going through some article regarding prostate cancer and found that ...

jeetu_g27

•2 days ago

5 Replies

update about CB-307 (CB307) for mCRPC: phase 1 trial recruiting

"...a novel half-life extended CD137 x PSMA Humabody for the selective activation of tumour-specific T cells exclusively within the tumour microenvironment....

"...a novel half-life extended CD137 x PSMA Humabody for the selective activatio...

Maxone73

•2 days ago

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AI to predict clinical trials outcome

"Dr. Sabbagh explains that traditional endpoints like overall survival often require long follow-ups, delaying access to potentially life-saving treatments....

"Dr. Sabbagh explains that traditional endpoints like overall survival often req...

Maxone73

•2 days ago

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ORIC-944: I am pretty sure it had a different name, but ok, inhibitor of PCR2 for CRPC

well, with a name that is the acronym of "overcoming resistance in cancer", we must keep an eye on this!...

well, with a name that is the acronym of "overcoming resistance in cancer", we m...

Maxone73

•2 days ago

1 Reply

Dad's PSA now 1800..nothing works..Is this the end??

Hey all, It pains me to write this as I'm probably scared to hear the truth. I've posted a few times, but this time, it's different. Dad was in hospital for...

Hey all, It pains me to write this as I'm probably scared to hear the truth. I'...

kikinini

•2 days ago

23 Replies

Phase 1/2: VIO-01 let's keep an eye on this

Also their other molecule AsiDNA is vey interesting. It seems that they have developed something that works like a PARPi without the side effects and without...

Also their other molecule AsiDNA is vey interesting. It seems that they have de...

Maxone73

•2 days ago

Be the first to reply

Transrectal biopsy affects PSA readings for how long?

Hi Guys, Greetings to all. Just Joined this board. The last PSA test which I did which led to my diagnosis was 21. Bone Mets and Gleason 9. Had a...

Hi Guys, Greetings to all. Just Joined this board. The last PSA test which...

Simpson80

•2 days ago

4 Replies

Eosinophilic Oesophagitis from ADT ?

Following some recent episodes of choking on fluids, I have had an edoscopy plus tissue biopsies which show eosinophilic oesophagitis. This can be simply...

Following some recent episodes of choking on fluids, I have had an edoscopy plus...

Leigh2350

•2 days ago

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Xtandi

I am using Xtandi about 2 months now. My doctor and I are afraid Xtandi may become resistant to the cancer. he target about 18 months only. Is there any...

I am using Xtandi about 2 months now. My doctor and I are afraid Xtandi may bec...

Domas

•2 days ago

8 Replies

After how long of starting orgovyx to check psa ?

Dad started relugolix around ten 10 days ago. It is an Indian company which is making it since recently. i wanted to check the efficacy of the tablets...

Dad started relugolix around ten 10 days ago. It is an Indian company which i...

Tinkudi

•2 days ago

2 Replies

Sclerosis due to cancer or treatment?

I recently developed sclerosis in my left hip area...painful to sit on a hard surface. PSMA tech wrote 'sclerosis developed consistent with treatment'....

I recently developed sclerosis in my left hip area...painful to sit on a hard su...

CoastalTex

•2 days ago

2 Replies

Trust in Healthcare virtual conference

Ten speaker online conference on Trust in Healthcare, premiering on Malecare's YouTube channel on Wednesday, June 26, 2024, from 12PM to 6PM ET. Free...

Ten speaker online conference on Trust in Healthcare, premiering on Malecare's Y...

Darryl

Partner•3 days ago

Be the first to reply

Posts - Advanced Prostate Cancer | HealthUnlocked

Advanced Prostate Cancer

All posts for June 2024

some news: new phase 0 trial for new radioligand gives good results

Phase 1b: FOR46, a novel antibody-drug conjugate targeting a tumor-specific epitope of CD46, in combination with Enza in patients with mCRPC

proof of concept CUPID trial finished, moving to 1b/2

Does this sound right? Any advice appreciated.

Interesting concept: More effective cancer treatment with iontronic pump

Lupron SEs - legs

Overcoming Pneumonia Susceptibility

Chemo Stopped working what's next? T Cell Therapy?

Castrate Resistant

DO YOU TRUST YOUR DOCTOR : Free registration at https://malecare.org/trust-in-healthcare

Phase 1: CBP-1018 interesting because it targets bone metastasis as well!

Phase 2 trial: Evaluation of Treatment Interruption After Response in mHSPC

I might have discovered a hidden gem: Clinical Investigators Provide Perspectives on the Current and Future Management of Prostate Cancer

Radioligand Therapy May Improve Radiographic Progression–Free Survival in Taxane-Naive Patients With Advanced Prostate Cancer

Should I do chemotherapy?

pathology report

Just a quick question.

When to Commence ADT and/or Androgen Blocking Therapy?

CC260 selective PI5P4Kα and PI5P4Kβ inhibitor

update about CB-307 (CB307) for mCRPC: phase 1 trial recruiting

AI to predict clinical trials outcome

ORIC-944: I am pretty sure it had a different name, but ok, inhibitor of PCR2 for CRPC

Dad's PSA now 1800..nothing works..Is this the end??

Phase 1/2: VIO-01 let's keep an eye on this

Transrectal biopsy affects PSA readings for how long?

Eosinophilic Oesophagitis from ADT ?

Xtandi

After how long of starting orgovyx to check psa ?

Sclerosis due to cancer or treatment?

Trust in Healthcare virtual conference

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