Combating Fatigue?? : My husband is on... - Advanced Prostate...

Advanced Prostate Cancer

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Combating Fatigue??

JolleySprings profile image
25 Replies

My husband is on Lupron/Casodex. He goes to gym 3 times per week for weight lifting plus Pickleball. He rides his bicycle 3-5 times per week about 15 miles. He is 69 and has been in perfect health until PC five years ago. Eats relatively clean. No red meat. Takes supplements suggested by nutritionist.

Even with all he does his fatigue and stamina are disheartening more days than not.

Some days he takes Vyvance if he really needs focus & energy to get something done!

Any suggestions as to what has worked for others?

Thank you!

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JolleySprings profile image
JolleySprings
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25 Replies
Schwah profile image
Schwah

He’s doing everything right. My only question is he putting in full effort weightlifting for at least an hour 3 days a week? All muscle groups. It takes a mean trainer yo push me. Loss of muscle is the biggest cause of fatigue in my opinion.

Schwah.

mrscruffy profile image
mrscruffy in reply to Schwah

I agree, I am working out 5 times a week and lifting super heavy. My trainer works with me most days and pushes me hard. Cheating with some compounds and have put 1 1/2 inches on my biceps. Also, intermittent fasting seems to help when I am not bulking

Schwah profile image
Schwah in reply to mrscruffy

Ok. Gotta hear what compounds you’re “cheating” with? I’ve hit a plateau. Not getting weaker but fighting to stay the same.

Schwah

in reply to mrscruffy

You are amazing . I Lost all muscle and with 3 t 7 yrs It ain’t coming back . My hope is neither will that pc ? Im stuck on skinny after 52 yrs of superb strength . Just me?

mrscruffy profile image
mrscruffy in reply to

I am doing this with super low T, the key is activating other hormones that create muscle

DSJo profile image
DSJo in reply to Schwah

As others have indicated he is doing everything right. I am into my second year of ADT and also work out (weights, aerobics) and I too suffer from fatigue and a whole lot of other stuff. In all the discussions with other guys on ADT one thing stands out - we all respond differently. Some suffer horribly while for others it is an inconvenience.

In addition to the 30% muscle mass loss, ADT also causes anemia and you are going to feel tired because of that. The mental stress of being diagnosed with cancer and the sexual health impact adds to the fatigue. Maybe he is exercising too much? I find I cannot do a workout and then do physical work the same day. It is one or the other. Best wishes.

JolleySprings profile image
JolleySprings in reply to DSJo

Thank you! Great suggestion!

mrscruffy profile image
mrscruffy

I am using a compound that is in the SARM category called Ostarine. Quick explanation is it suppresses T and tells all other hormones to build muscle fast. Stopped my PSA from rising. Funny thing is my Oncologist knew exactly what it was and was aware of the affect on PSA. He couldn't tell me to take it but off the books said he was good with it. It was successful in muscle building and PSA drop. It has never been FDA approved but is legal to purchase, legal to posses but not for human consumption. Do some research on it. If you choose to use it consult with someone that has experience using it. My trainer helped me and actually introduced me to the idea. Any questions feel free to ask

in reply to mrscruffy

Thank you . It’s great that you’re seeing results! 😎👏👏👏

lopwillie profile image
lopwillie in reply to mrscruffy

Hi Mrscruffy, I read a little about Ostarine, and could not find anything negative! so I wish to give it a try. My questions are pills or liquid? Quantity ? and, If you don't mind who do you buy it from? I am on ADT vacation right now only use small .025 Estradiol patch (twice-weekly) which works great for clearing brain fog and reduces hot flashes. My PSA is staying low at 0.09, with T @ 14. I have low energy and have lost a lot of muscle, and added extra fat. My Oncologist does not want to talk about BAT or T-shots. I shoot pool with the fella 3/4 times a week and putt around the yard for an hour or so. I can't seem to get myself to the gym, and get tired walking around the market or across the parking lot. I'am hopeful Ostarine will give me a kick in the pants. Thanks for your help, William, also known as lopwillie .

mrscruffy profile image
mrscruffy in reply to lopwillie

Ostarine is a tricky one to use and takes a little experimentation. The only side effect is a decrease in HDL and in mega doses can affect liver. I use bout 1/10 a dose where problems occur. I am currently 5'10" 220 lbs. I took baseline reading of HDL before starting, It is mandatory to use it in cycles, each cycle culminating with 4 weeks off cycle. My first cycle was 4 weeks of 10mg pills daily. After two weeks I began to see noticeable growth in biceps. After cycle checked my HDL and it actually went up which is good. Second cycle was 6 weeks at 20mg. I began to see fatigue in week 5 and after cycle my HDL went down which is not good. I added 1 1/2" to my biceps after 10 weeks increased weights I was lifting and my legs are super strong. So just completed off cycle and am now doing 15mg for 6 weeks. So far no fatigue and when done will check HDL again. I go to the gym 5 days a week and ride my bike on off day. This is a bit extreme but I am now obsessed with building muscle. 3-4 days a week would be fine. My motivation is in the positive changes to my body. When using Ostarine I eat about 120+ grams of protein and some supplements to build muscle, mostly from shakes, fowl and fish. I gain weight when doing this and drop it during rest cycle. Ostarine is considered to be for animal testing only but it is legal to buy and possess but not for human consumption. I purchase my SARMS from SARMS Global. Only buy from reputable supplier as there are many fakes out there. As an added bonus I have a trainer that works out with me most days, she is motivating and easy on the eyes so the gym is fun for me. If I left anything out feel free to ask

I like what he’s doing . Without t there is little energy . Sam- e pepped me up out of total lethargy into just a plain low energy guy! Which came first ? The chicken or the egg? We need to exercise to get up our energy but ..without t there is no drive .to do so ? Walking at least every day helps . But he’s working out . It’s a grind , but I commend him . If we just roll over and become inactive we’ll fade into the dust quickly .

Scout4answers profile image
Scout4answers in reply to

First time I have heard SAM-e mentioned on here...I have been taking it for 15-20 years 200 mg daily

in reply to Scout4answers

I’ve been on it 4 yrs years myself . 😂👍

JolleySprings profile image
JolleySprings in reply to

Does it cause issues with liver enzymes etc?

lopwillie profile image
lopwillie in reply to Scout4answers

Hi Scott4answers, My I ask where do you buy the Ostarine? I wish to give it a try. Thanks William

Scout4answers profile image
Scout4answers in reply to lopwillie

I do not use Osterine ask MrScruffy. I would like to know as well. ;-)

London441 profile image
London441

Schwah makes sense on this, as he often does. We can’t know his level of effort. I’m not claiming he doesn’t work hard, but I am saying that most older guys who lift do not work nearly hard enough to make a real difference.

Weight lifting comes in 2 basic forms, max effort and varying amounts of ordinary effort. Max effort also also takes several forms, none of which are for everyone. Maximum effort is unpleasant, difficult, and on ADT can be frustrating and demoralizing.

However, consistent max effort produces exquisite results. The body still suffers the ravages of ADT, especially cosmetically, but these ravages are lessened dramatically.

Lifting with max effort is also a supreme mood elevator, far superior to drugs. The ultimate fatigue killer. Keeps sarcopenia and other co morbidities at bay when paired with even a reasonably good diet.

Mr Scruffy likes heavy weight and that’s great. But trust me you don’t need heavy weight to get strong. One needs to work hard though. I always recommend a trainer if you can afford one.

No17 profile image
No17 in reply to London441

I wouldn't have said it better myself thanks

SteveTheJ profile image
SteveTheJ

Talk to your doctor about Provigil. It's working well for me, esp with alertness.

Weightlifting, sure <rolls eyes> but unless you're losing a lot of muscle mass IMHO that's a salve to vanity and ego.

Best of luck.

Horse12888 profile image
Horse12888

My belief is that if the SEs of GnRH drugs are intolerable even with exercise and drugs to mask the SEs, it makes sense to use high-dose transdermal estradiol instead, like they do outside the US. Achieves castration with very mild SEs. This is certainly what I'll be doing when/if the time comes.

cancerfox profile image
cancerfox

I keep seeing this bs that if you work out really, really hard it is a substitute for not having testosterone in your body. That's like saying if you have no gas in your car you should drive really, really fast and it will make up for an empty tank. From my personal experience, neither one of these works very well. Your husband shouldn't beat up on himself for something beyond his control; having no testosterone in your body is brutal, and he's doing everything he can to stay fit in spite of this handicap.

PBnative profile image
PBnative

I also take Vyvanse daily for mood swings and other adult ADD symptoms . I’m grateful that it still works so well for me after 20+ years

j-o-h-n profile image
j-o-h-n

Wear something skimpy and let him chase you around the house........

Good Luck, Good Health and Good Humor.

j-o-h-n Wednesday 04/20/2022 11:43 PM EST

Carlosbach profile image
Carlosbach

After starting Zytiga and Lupron I had a lot of fatigue, but I pushed myself to walk 6-7 days a week. Over time the fatigue lessened, but I had also lost muscle mass and strength. On the advice of several people on this forum I added weight lifting to my regime. The weights have made a significant improvement in my overall strength, health and sense of vitality. However, it took a while for me to adjust to my new limits. In addition to alternating walking and lifting days, I had to change my protein intake (I'm on a plant based diet, so that primarily means beans, beans and beans). I also now only work out 6 days a week, and take 1 day of rest each week. As a result my recovery time has improved, I am now walking twice as far, and I can actually get my biceps to pop again.

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