Posts - Advanced Prostate Cancer | HealthUnlocked

Advanced Prostate Cancer

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Podcast Episode with Abraham Morgentaler, MD about Testosterone and Prostate Cancer

This great podcast, "You are not broken," is by a female urologist, Dr. Kelly Casperson. She often explores misconceptions about hormones. This episode with...

This great podcast, "You are not broken," is by a female urologist, Dr. Kelly Ca...

Chris_Ali

•15 days ago

5 Replies

Could BAT be our last chance?

My husband (on Lupron, castration resistant and tried every treatment) checked into the hospital 10 days ago for intense bone pain that requires heavy...

My husband (on Lupron, castration resistant and tried every treatment) checked i...

Chris_Ali

•15 days ago

22 Replies

Gaurdant blood test

My test revealed a mutation called Andorogen receptor Amplification. This explains how it went from my L2 to my rib, femurs, and lower back. My doctor did...

My test revealed a mutation called Andorogen receptor Amplification. This expla...

crony

•26 days ago

10 Replies

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Meeting with our oncologist for castrate resistance metastatic prostate cancer

We met with my Dad's MO yesterday. (Diagnosed 10/22 with advanced metastatic cancer, became castrate resistant about a year ago.) He shared that the Xtandi...

We met with my Dad's MO yesterday. (Diagnosed 10/22 with advanced metastatic can...

lgutman

•1 month ago

23 Replies

High volume, advanced metastatic prostate cancer

Hello. I am looking for guidance. My dad (now 81) was diagnosed with metastatic prostate cancer at the initial point of diagnosis in the ER on 10/25/2022. It...

Hello. I am looking for guidance. My dad (now 81) was diagnosed with metastatic ...

lgutman

•2 months ago

10 Replies

CDK 12 mutation and Immunotherapy

Hi All, My PSA as is starting to rise on Arbi/Dexa. I have the CDK12 mutation which is apparently known to be a drug target or to predict sensitivity to...

Hi All, My PSA as is starting to rise on Arbi/Dexa. I have the CDK12 mutation w...

MikeMartin

•3 months ago

11 Replies

Talazoparib with Xtandi

All, I’m starting talazoparib 0.5 mg this week in combo with Xtandi and Lupron. I’ve been on Lupron and Xtandi for 7 months without issue. I’m now in...

All, I’m starting talazoparib 0.5 mg this week in combo with Xtandi and Lupron. ...

revchris77

•6 months ago

5 Replies

New hope for castrate resistant prostate cancer on the horizon

A new experimental drug is in development that reverses castrate resistance and makes the cancer amenable to further treatment. Early days yet but it looks...

A new experimental drug is in development that reverses castrate resistance and ...

GeorgesCalvez

•6 months ago

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Tamarack Clinical Trial

Has anyone enrolled in this latest targeted (non PSMA) treatmentt?

u302000

•9 months ago

6 Replies

Interesting albeit Preliminary - Cholesterol

https://medicine.wustl.edu/news/study-reveals-how-treatment-resistant-prostate-cancer-supplies-its-own-hormonal-fuel/?utm_medium=email&utm_source=rasa_io&utm_ca

https://medicine.wustl.edu/news/study-reveals-how-treatment-resistant-prostate-c...

Hawk56

•11 months ago

6 Replies

Xtandi leftovers

Hi Guys, Since Xtandi is no longer effective for me, I would like to sell the remaining boxes at a low price. If interested, please write to me at...

Hi Guys, Since Xtandi is no longer effective for me, I would like to sell the ...

tarzantass

•11 months ago

2 Replies

Fosfestrol ( oral Estrogen )/ Honvan for mCRPC progression ?

Complete case history in profile. Current therapy: ADT + Abiraterone + Pred PSA has gradually increase from a nadir of .7 in july 2022 to 4.5 in...

Complete case history in profile. Current therapy: ADT + Abiraterone + Pred ...

meowlicious99

•1 year ago

16 Replies

Docetaxil first, then Pluvicto or Pluvicto first

Zytiga failed and Dr Milowsky, my MO at Lineberger Cancer Ctr recommends I go on chemotherapy first and if or when that fails, go to Pluvicto. Dr Almaguel, a...

Zytiga failed and Dr Milowsky, my MO at Lineberger Cancer Ctr recommends I go on...

Flyfisherbug

•1 year ago

35 Replies

Future treatment

Non metastatic castration resistant prostate cancer - C61 cancer prostata operata pT3a NX M0, Gleason 3+4=7, PSA 12,6 PD 09/07. nmCRPC 04/19. I was taking...

Non metastatic castration resistant prostate cancer - C61 cancer prostata operat...

Jansverr

•1 year ago

2 Replies

Aetna denied request for PSMA scan

My PSA has gone up from .1 t0 3.5 in the last 6 months. Aetna told me to go pound sand and denied my request for the PSMA scan. Does anyone know how much it...

My PSA has gone up from .1 t0 3.5 in the last 6 months. Aetna told me to go pou...

Jamesjohn63

•2 years ago

47 Replies

Lu 177 also failed after 6 Cycles. 16 rounds of Chemo (10 Docxetexal and 6 Jevtana) previously failed. What could be next?

Thanks to the community for taking out time and embarking on knowledge and empowerment for patients and families who are struggling to survive this testing...

Thanks to the community for taking out time and embarking on knowledge and empow...

Shahbazahmedazmi

•2 years ago

29 Replies

Swollen legs on Zytiga and Prednisone

Short update on my fathers health and hoping to get some advise. My father started on Zytiga in October 2020. His PSA at the time was around 750 ng/mL. His...

Short update on my fathers health and hoping to get some advise. My father start...

pozitronij

•2 years ago

37 Replies

My #1 support person & me

I'm new to the form. I have mcrpc. I was on lupron injections for almost 1 year. I didn’t like the pain for 5 days after injection plus insurance only paid...

I'm new to the form. I have mcrpc. I was on lupron injections for almost 1 year....

Canis-Lupus53

•2 years ago

9 Replies

Resistant to Zytiga, Xtandi and Chemo? Here is a promising trial.

At the recent ASCO GU 2022 conference the results of the CYPIDES trial were presented. This trial tested the new drug ODM-208 which can be effective after...

At the recent ASCO GU 2022 conference the results of the CYPIDES trial were pres...

GP24

•2 years ago

14 Replies

Xofigo

I’m starting Xofigo next week. Anything special I should know? Side effects? I’d love to hear your experience. Thanks.

I’m starting Xofigo next week. Anything special I should know? Side effects? I’...

Foldem

•2 years ago

9 Replies

Prednisone and rotator cuff repairs.

Concerned 5mg prednisone slowly affecting shoulder tendons….pain increasing. Took higher dose in 2016 for inflammation and rotator cuff repair greatly...

Concerned 5mg prednisone slowly affecting shoulder tendons….pain increasing. To...

Leader4077

•2 years ago

2 Replies

Update - ADT with Zytiga Failure (Castration Resistant) after 6 Months (PSA 90.3); Firmagon still Working; PSMA PET Scan Ordered

I came right out of the gate with Gleason 9 Stage 4 Advanced Prostate Cancer with more than 5 Metastases in January of this year. Firmagon brought the...

I came right out of the gate with Gleason 9 Stage 4 Advanced Prostate Cancer wit...

diamondrn

•2 years ago

3 Replies

Does this sound familiar on ADT

Doing a study on Androgen and came accross this photo, look familiar? This is why we have some of these side effects with ADT.

Doing a study on Androgen and came accross this photo, look familiar? This is wh...

Hidden

•2 years ago

63 Replies

How long can I expect Xtandi to work

I have been on Xtandi a few months and the results are very good. I was on Lupron 10 years before it quit working. How long can I expect Xtandi to work before...

I have been on Xtandi a few months and the results are very good. I was on Lupro...

jbskiatook

•2 years ago

58 Replies

My experience with Lu-177

Dear fellows in misfortune. I’d like express here my experience with the LU-177 PSMA-617. Diagnosed in June 2020 following an iliac thrombosis, with a PSA of...

Dear fellows in misfortune. I’d like express here my experience with the LU-177 ...

Loujaro

•2 years ago

13 Replies

XTANDI dosage questions - do we need a different dosage to attain steady state and to maintain steady state??

Has anyone seen – or done some calculations on Xtandi dosage? From what I can see they arrived at 160 as the standard dosage after trials showed increasing...

Has anyone seen – or done some calculations on Xtandi dosage? From what I can se...

Stoneartist

•2 years ago

20 Replies

prednisone dosage with abiraterone

From the janssenlabels product insert: " Metastatic castration-resistant prostate cancer: • ZYTIGA 1,000 mg orally once daily with prednisone 5 mg orally...

From the janssenlabels product insert: " Metastatic castration-resistant pro...

meowlicious99

•2 years ago

4 Replies

DOWN THE WELL TRODDEN PATH

Just got the latest blood results - which show a further rise of PSA - thus confirming I have reached Castrate Resistant. PSA was falling nicely until a nadir...

Just got the latest blood results - which show a further rise of PSA - thus conf...

Stoneartist

•3 years ago

6 Replies

Phase 3 trial 177-Lu-PSMA-617

Is anyone in the in the Phase 3 trial going on at UCSF & Stanford that started in 2018 that will conclude August 2022. Any updates as to how it’s going...

Is anyone in the in the Phase 3 trial going on at UCSF & Stanford that started ...

Bubasurf6

•3 years ago

12 Replies

CRISPR

https://www.medpagetoday.com/neurology/generalneurology/93314?xid=nl_covidupdate_2021-06-28&eun=g1876633d0r&utm_source=Sailthru&utm_medium=email&utm_campaign=Da

https://www.medpagetoday.com/neurology/generalneurology/93314?xid=nl_covidupdate...

Spyder54

•3 years ago

5 Replies

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Posts - Advanced Prostate Cancer | HealthUnlocked

Advanced Prostate Cancer

Castrate Resistent posts

Podcast Episode with Abraham Morgentaler, MD about Testosterone and Prostate Cancer

Could BAT be our last chance?

Gaurdant blood test

Meeting with our oncologist for castrate resistance metastatic prostate cancer

High volume, advanced metastatic prostate cancer

CDK 12 mutation and Immunotherapy

Talazoparib with Xtandi

New hope for castrate resistant prostate cancer on the horizon

Tamarack Clinical Trial

Interesting albeit Preliminary - Cholesterol

Xtandi leftovers

Fosfestrol ( oral Estrogen )/ Honvan for mCRPC progression ?

Docetaxil first, then Pluvicto or Pluvicto first

Future treatment

Aetna denied request for PSMA scan

Lu 177 also failed after 6 Cycles. 16 rounds of Chemo (10 Docxetexal and 6 Jevtana) previously failed. What could be next?

Swollen legs on Zytiga and Prednisone

My #1 support person & me

Resistant to Zytiga, Xtandi and Chemo? Here is a promising trial.

Xofigo

Prednisone and rotator cuff repairs.

Update - ADT with Zytiga Failure (Castration Resistant) after 6 Months (PSA 90.3); Firmagon still Working; PSMA PET Scan Ordered

Does this sound familiar on ADT

How long can I expect Xtandi to work

My experience with Lu-177

XTANDI dosage questions - do we need a different dosage to attain steady state and to maintain steady state??

prednisone dosage with abiraterone

DOWN THE WELL TRODDEN PATH

Phase 3 trial 177-Lu-PSMA-617

CRISPR

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