Posts - Advanced Prostate Cancer | HealthUnlocked

Advanced Prostate Cancer

21,035 members • 26,216 posts

All posts for February 2024

PSA doubled in last 30 days after 4 months stable since Provenge. What's next?

Update: PSA remained roughly 1.7 to 1.8 for last 4 months after Provenge but yesterday's 30-day PSA test revealed a jump to 3.190 so something is growing...

Update: PSA remained roughly 1.7 to 1.8 for last 4 months after Provenge but yes...

SViking

•2 months ago

10 Replies

Clinical Trial PT 112 ?

I’m writing for my husband who is French (I’m English : we live in France ) He’s 65 and was diagnosed in March 2022 - already metastatic : PSA 36 (previous...

I’m writing for my husband who is French (I’m English : we live in France ) He...

Enilorac63

•2 months ago

3 Replies

Dr. "Snuffy" Myers daughter talks about the day she heard about her Dad's diagnosis

https://youtu.be/k0vmB-fgxQc Click here to subscribe: https://www.youtube.com/c/malecare?sub_confirmation=1 Jessie Myers, daughter of prostate cancer legend...

https://youtu.be/k0vmB-fgxQc Click here to subscribe: https://www.youtube.com/...

Darryl

Partner•2 months ago

6 Replies

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Decipher prostate test receives high evidence rating in NCCN guidelines

https://www.urologytimes.com/view/decipher-prostate-test-receives-high-evidence-rating-in-nccn-guidelines

https://www.urologytimes.com/view/decipher-prostate-test-receives-high-evidence-...

zeitgeistxx

•2 months ago

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Anything new on sabizabulin?

I can't find any current info on clinical trials continuing on this drug. Here's a link about the Phase Ib/II Study of Sabizabulin. Thanks for any info...

I can't find any current info on clinical trials continuing on this drug. Here'...

SuppWife

•2 months ago

1 Reply

osterine- questions

wonder if anyone has a good source for osterine? Is there someone who can give guidance on dosage? Did anyone get joint pain relief as a result of using...

wonder if anyone has a good source for osterine? Is there someone who can give...

Steel67

•2 months ago

5 Replies

Is it PSA recurrence or not...

My friend had a radical prostatectomy a year ago. Since then his monthly PSA results were stable, at 0.006 3 months ago his PSA went from 0.006 to 0.012, then...

My friend had a radical prostatectomy a year ago. Since then his monthly PSA res...

traveller64

•2 months ago

13 Replies

PSA vs Testosterone Nadir for CRPC and Non-CRPC

This plot from Safriadi (2022) compares the mean values of PSA nadir versus Testosterone Nadir comparing Non-Castrate Resistant PC (Non-CRPC) to...

This plot from Safriadi (2022) compares the mean values of PSA nadir versus Test...

janebob99

•2 months ago

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Prednisone

What is protocol for weaning off of prednisone?

Scout4answers

•2 months ago

44 Replies

Barrigel is now preferred over "SpaceOAR" gel?

Consulted by video with the doctor who is supposed to install my SpaceOAR in preparation for my IMRT. His first words were "we don't use SpaceOAR gel anymore....

Consulted by video with the doctor who is supposed to install my SpaceOAR in pre...

mababa

•2 months ago

16 Replies

T + Chemo?

Hi guys, This may be a dumb question but my understanding of chemo is that it is most effective when the cancer is growing rapidly. Would it be of any use to...

Hi guys, This may be a dumb question but my understanding of chemo is that it i...

Bruce66

•2 months ago

4 Replies

Mortality Probability after first PSA rise vs non-castrate testosterone levels (low vs Normal)

Here's a plot from Atkins (2018) that shows the Percent risk of Prostate Cancer-specific Mortality versus time following a first PSA failure, for two...

Here's a plot from Atkins (2018) that shows the Percent risk of Prostate Cancer...

janebob99

•2 months ago

21 Replies

Rising PSA post RP,IRT,ADT

Have 2 consecutive rising PSA - .04,.05,.1. Year post RP,IRT,ADT.. understand if goes to .2 new scans and possible Radiation. I surely don't like the ADT.....

Have 2 consecutive rising PSA - .04,.05,.1. Year post RP,IRT,ADT.. understand i...

ChristopherH

•2 months ago

2 Replies

First PSA after RARP

My dad had RARP on Jan 19,2024. Gleason 8(4+4) PSA 12, clean PSMA pet scan before surgery. Path report had no LN SVI or EPE but PNI and 50 percent prostate...

My dad had RARP on Jan 19,2024. Gleason 8(4+4) PSA 12, clean PSMA pet scan befor...

Pca2024

•2 months ago

11 Replies

Docxtel triple therapy?

Thank you for sharing your thoughts. My dad--81, advanced metastatic castrate resistant Diagnosed at 79 with stage 4 met 8 bones, including skull, no...

Thank you for sharing your thoughts. My dad--81, advanced metastatic castrate ...

lgutman

•2 months ago

1 Reply

PSA reduction after Estrogen Patch Therapy

Here's a revised plot of PSA reduction due to castration from Estrogen Patch therapy. The previous version had the wrong time scale. That has been corrected...

Here's a revised plot of PSA reduction due to castration from Estrogen Patch the...

janebob99

•2 months ago

2 Replies

Dad's PSA risen from 0.01 to 0.05 in 2 months, 2 years post SRT. Any chance that there is no further progression?

PSA has risen 3 times in a row. I understand the figure is still low, but is this a definite indication that it will progress, or is there a chance that PSA...

PSA has risen 3 times in a row. I understand the figure is still low, but is thi...

MsBoBo

•2 months ago

2 Replies

The De-Escalate Trial: Intermittently Stopping Prostate Cancer Treatments to Improve QoL

as the title says:...

Maxone73

•2 months ago

1 Reply

What AI Says About Supplements and Off-Label Drug Use Regarding Prostate Cancer

Sure wish I had this tool over 2 years ago when I started reading up although you can't 100% trust the answers. The tools are getting smarter. I'm a software...

Sure wish I had this tool over 2 years ago when I started reading up although yo...

jazj

•2 months ago

7 Replies

PSA drop with decreasing Testosterone after Estrogen Patch Therapy

Here's a plot that I made from data taken from the PATCH estrogen patch therapy study. It plots the % reduction in PSA from baseline (100%) at time = 0 as a...

Here's a plot that I made from data taken from the PATCH estrogen patch therapy ...

janebob99

•2 months ago

2 Replies

Elevated Liver Enzymes

Husband on Triplet Therapy Orgovyx, Nubeqa and Docetaxel for Stage IV GL9 with bone mets. First chemo cycle completed. Second chemo was canceled as his ALT...

Husband on Triplet Therapy Orgovyx, Nubeqa and Docetaxel for Stage IV GL9 with b...

Cali3

•2 months ago

6 Replies

PSA spiked from .6 to 8.0 in 3 months

The blood test corroborates the MRI that shows spread. I am talking with Dr Goodman in the AM. Am I doomed? My PSA has never been 8. before

The blood test corroborates the MRI that shows spread. I am talking with Dr Goo...

crony

•2 months ago

50 Replies

At the crossroads (again)

My profile is up to date, but, briefly, have failed chemo, ADT (am castrate resistant), failed Keytruda and now Pluvicto. Scans yest. & today show progression...

My profile is up to date, but, briefly, have failed chemo, ADT (am castrate resi...

rsgdmd

•2 months ago

16 Replies

Is This Normal??

Is it normal after nearly 5 years on ADT + Zytig, Prednisone, and Xgeva, to have constant "Flu-Like" symptoms, (sans a fever)? Some days, everything hurts,...

Is it normal after nearly 5 years on ADT + Zytig, Prednisone, and Xgeva, to have...

TommyCarz2

•2 months ago

3 Replies

Patches (I'm depending on you, son)

Dated pop reference - sorry. While my research has continued, my oncologist has nothing to give me within the SOC to keep the PSA in check. Now I've...

Dated pop reference - sorry. While my research has continued, my oncologist has...

CrocodileShoes

•2 months ago

7 Replies

Any positive or Negative review of Provenge?

I am collecting all feedback on Provenge treatment. My MO did not talk further and did not believe in it, so I am now collecting feedback and learning more...

I am collecting all feedback on Provenge treatment. My MO did not talk further a...

God_Loves_Me

•2 months ago

44 Replies

AUS revision surgery?

I'm seeking advice on having a second AUS surgery. My background: I had a prostatectomy in 2016 and radiation a year later because the cancerous tumor had...

I'm seeking advice on having a second AUS surgery. My background: I had a prosta...

allnewstuff

•2 months ago

7 Replies

Starting EBRT on Monday… advice?

Just looking for advice. Doing 28 fractions starting Monday at Emory/Winship. Specifically: EBRT using photons – plan is for 50.4 to whole Pelvis, ~55 to...

Just looking for advice. Doing 28 fractions starting Monday at Emory/Winship. ...

Jpburns

•2 months ago

15 Replies

Feasibility of someone from out of USA joining a clinical trial in USA?

My father has Prostate cancer (stage IV) and High Grade Neuro-endocrine cancer / Small Cell Carcinoma in liver. His six doses of Chemotherapy (carboplatin +...

My father has Prostate cancer (stage IV) and High Grade Neuro-endocrine cancer /...

RindaMan

•2 months ago

3 Replies

Pain Management

Dear All can anyone help. Diagnosed with stage 1V advanced metastatic prostate cancer December 2022. 6 sessions of Chemo, then Firmagon and Nubeqa PSA was...

Dear All can anyone help. Diagnosed with stage 1V advanced metastatic prostate...

Nyon

•2 months ago

14 Replies

Posts - Advanced Prostate Cancer | HealthUnlocked

Advanced Prostate Cancer

All posts for February 2024

PSA doubled in last 30 days after 4 months stable since Provenge. What's next?

Clinical Trial PT 112 ?

Dr. "Snuffy" Myers daughter talks about the day she heard about her Dad's diagnosis

Decipher prostate test receives high evidence rating in NCCN guidelines

Anything new on sabizabulin?

osterine- questions

Is it PSA recurrence or not...

PSA vs Testosterone Nadir for CRPC and Non-CRPC

Prednisone

Barrigel is now preferred over "SpaceOAR" gel?

T + Chemo?

Mortality Probability after first PSA rise vs non-castrate testosterone levels (low vs Normal)

Rising PSA post RP,IRT,ADT

First PSA after RARP

Docxtel triple therapy?

PSA reduction after Estrogen Patch Therapy

Dad's PSA risen from 0.01 to 0.05 in 2 months, 2 years post SRT. Any chance that there is no further progression?

The De-Escalate Trial: Intermittently Stopping Prostate Cancer Treatments to Improve QoL

What AI Says About Supplements and Off-Label Drug Use Regarding Prostate Cancer

PSA drop with decreasing Testosterone after Estrogen Patch Therapy

Elevated Liver Enzymes

PSA spiked from .6 to 8.0 in 3 months

At the crossroads (again)

Is This Normal??

Patches (I'm depending on you, son)

Any positive or Negative review of Provenge?

AUS revision surgery?

Starting EBRT on Monday… advice?

Feasibility of someone from out of USA joining a clinical trial in USA?

Pain Management

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