Do I have a thyroid (Hashimoto's) issue, or is ... - Thyroid UK

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Do I have a thyroid (Hashimoto's) issue, or is it sex hormones?

PelotonRider profile image
8 Replies

Hi,

When I reported my thyroid results previously to you marvellous, supportive folks I had been told I had Hashimoto's. My Thyroid antibodies were very high. Since then I've eliminated gluten and most cow dairy from my diet. I've had my bloods redone and would be interested in opinions on whether Hashimots's OR , as a woman of a certain age sex hormones OR I'm a poor metaboliser is the issue. I've had numerous bloods done including: thyroid, nutrition and sex hormones. Blood draw was first thing, fasted and I stopped my nutritional supplements 5 days prior.

Given I'm taking oestrogen (spray 3 pumps), Progesterone tablet (1xday), VitD3, Omega3, Mg, B-complex and a joint supplement. I'm surprised at how low some of my nutritionals are. I'm looking for balance, but cant find it - or the weight loss i need...

I'd value any opinions - need for more/less HRT, nutritional supplements, thyroid meds ..... The suggestion currently is to start testosterone and up my D3, Mg and B's....

Thyroid Stimulating Hormone (TSH) 3.1 mIU/l 0.351 - 5.5 Optimal

Free Thyroxine (FT4) 15.1 pmol/l 11.91 - 21.6 Optimal

Free Tri-iodothyronine (FT3) 4.54 pmol/l 3.11 - 6.8 Optimal

Anti-Thyroglobulin Antibody (Anti-Tg) 36 IU/ml ≤115.0 Optimal

Anti-Thyroid Peroxidase Antibody (Anti-TPO) 194 kU/l ≤34.0 Optimal >34.0 High

Vitamin B12 498 ng/l (197 - 771)

Vitamin D 77 nmol/l (50 - 375)

Iron 18.7 µmol/l (5.8 - 34.5)

Ferritin 68.7 µg/l (10 - 120)

Calcium (adjusted) 2.28 mmol/l (2.2 - 2.6)

Magnesium 0.9 mmol/l (0.7 - 1.1)

Zinc 20 µmol/l (>17.5 High)

Folic acid 8.6 µg/l (3.8 - 26.8)

Vitamin B12 498 ng/l (197 - 771)

Vitamin D 77 nmol/l (50 - 375)

Follicle Stimulating Hormone 6.3 U/l

Oestradiol 485 pmol/l

Progesterone 2.54 nmol/l

Prolactin 369 mIU/l ( 102 - 496)

Testosterone 0.307 nmol/l (0.1 - 1.42)

Sex Hormone Binding Globulin 79.5 nmol/l ( 27.1 - 128.0)

Free Androgen Index 0.39 ( 0.19 - 3.63)

Apologies, now I've typed this it feels like an essay!

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PelotonRider
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TiggerMe profile image
TiggerMeAmbassador

TSH 3.1 mIU/L (0.351 - 5.5) 53.4%

Free T4 (fT4) 15.1 pmol/L (12 - 22) 31.0%

Free T3 (fT3) 4.54 pmol/L (3.1 - 6.8) 38.9%

T4:T3 Ratio 3.326 

So not really optimal as suggested, your free's have risen a little... but like you say even with supplements your vits and min levels are still on the low side, which B complex are you taking as it isn't doing the trick with B12 and folate still too low?

TPO has lowered thanks to the dietary changes

Vit D aiming for 125nmol/L a loading dose might be the way to go here to get things moving grassrootshealth.net/projec...

Sex hormones I'd be inclined to lose a squirt of oestrogen and add a dab of testosterone 🤗

PelotonRider profile image
PelotonRider in reply toTiggerMe

Thanks for taking the time to comment TiggerMe. I have been taking a B complex, but only 1 x tablet so will increase this to 2. I have a VitD3 & K spray but haven't been very good at taking it so will make this a better part of my regiem. Going to start testosterone tomorrow... Hoping these tweaks helps... At least dietary tweaks have helped a bit :)

TiggerMe profile image
TiggerMeAmbassador in reply toPelotonRider

Us testosterone users opt for the butt cheeks as less hair follicles to stimulate 😊 so far so good!

Worth double dosing your Vit D for a couple of weeks 🤗

PelotonRider profile image
PelotonRider in reply toTiggerMe

Just applied to my inner forearm! Button checks tomorrow.... yes, upping my supplements tomorrow onwards.... hoping the exhausted pigeon flys away and leaves a spring chicken for Christmas!

greygoose profile image
greygoose

All hormones are inter-connected, and if one is out of kilter it's going to have a knock-on effect on the others. Low thyroid hormones are going to cause low sex hormones. Correct the thyroid hormones and the sex hormones should balance out.

Thyroid Stimulating Hormone (TSH) 3.1 mIU/l 0.351 - 5.5 Optimal

0.351-5.5 is the so-called 'normal' range. It has nothing to do with 'optimal'.

A 'normal' (euthyroid) TSH would be about 1. At 2 the thyroid is struggling. And at 3 you are technically hypo. So a TSH of 5.5 is very far from 'optimal'. Your TSH is saying that you are hypo.

In any case, there's no such thing as and 'optimal' TSH. The TSH rises and falls following the thyroid hormone levels - T3 and T4. It is especially the T3 that needs to be optimal and that is a feeling, not a number. Optimal is the level at which you feel well.

Free Thyroxine (FT4) 15.1 pmol/l (11.91 - 21.6) 32.92%

Your FT4 is very low, should be at least over 50%

Free Tri-iodothyronine (FT3) 4.54 pmol/l (3.11 - 6.8) 38.75%

Your T3 is just slightly higher, which is abnormal in itself - the FT3 is usually slightly lower in range than the FT4 - which, in itself, is a sign that the thyroid is failing.

So, those three results in themselves are saying 'hypo'.

What time of day was the blood draw for these results? TSH is highest before 9 am and then drops to its lowest around midday.

Anti-Thyroglobulin Antibody (Anti-Tg) 36 IU/ml ≤115.0

Negative.

Anti-Thyroid Peroxidase Antibody (Anti-TPO) 194 kU/l ≤34.0

Positive. You have Hashi's, no doubt about it. And given your thyroid hormone results, the thyroid has already been damaged.

Vitamin B12 498 ng/l (197 - 771)

A little too low - would be better over 550.

Folic acid 8.6 µg/l (3.8 - 26.8)

This result is actually folate. Folic acid is synthetic folate, so you can't test for it. And it's too low. It should be more like 15/mid-range.

So, taking a methylated B complex would be a good idea to bring these two levels up.

Vitamin D 77 nmol/l (50 - 375)

Too low. Should be more like mid-range.

Iron 18.7 µmol/l (5.8 - 34.5)

Ferritin 68.7 µg/l (10 - 120)

These are on the low-side, so it would be a good idea to increase your intake of iron-rich foods. But don't forget to eat a good source of vit C - or take supplements - at the same time to increase absorption.

Calcium (adjusted) 2.28 mmol/l (2.2 - 2.6)

Low-ish. But if you supplement your vit D, it will increase your absorption of calcium from food. But you need to take vit K2-MK7 with it to make sure that extra calcium goes into the bones and teeth and doesn't build up in the soft tissues and arteries.

Magnesium 0.9 mmol/l (0.7 - 1.1)

No point in testing magnesium because the results are not reliable. Just take some - especially if you are taking vit D, the two work together. Most people are deficient in magnesium, anyway, and being hypo will make it worse.

Zinc 20 µmol/l (>17.5 High)

As your zinc is high, your copper is more than likely low. You might benefit from taking a little copper.

The fact that your nutrients are on the low-side is more indication that you are hypo. When you are hypo, your stomach acid is usually low, meaning that you have difficulty digesting your food and absorbing nutrients.

would be interested in opinions on whether Hashimots's OR , as a woman of a certain age sex hormones OR I'm a poor metaboliser is the issue.

Yes to all three. You do have Hashi's, and that is your main problem. Given your age, your sex hormone production is bound to be reducing, but this will be exacerbated by having low thyroid hormone levels. Not quite sure what you mean by 'poor metaboliser' but being hypo will have a huge effect on your metabolism, that's for sure.

Your problem is going to be getting a doctor to take all this seriously. Your TSH would have to be at least over-range to get them to take an interest - probably over 10!

Given I'm taking oestrogen (spray 3 pumps), Progesterone tablet (1xday), VitD3, Omega3, Mg, B-complex and a joint supplement. I'm surprised at how low some of my nutritionals are. I'm looking for balance, but cant find it - or the weight loss i need...

What is in your joint supplement? Be very careful of supplements that contain more than one nutrient. One of the ingredients could be wrong for you, or not appropriate with the other ingredients.

Which B complex are you taking?

How much vit D and magnesium?

The balance you need you will find when you optimise your thyroid hormones for you as an individual. And the difficult part is not finding that balance but finding a doctor that gives you the freedom to look for it.

PelotonRider profile image
PelotonRider in reply togreygoose

Thanks Greygoose, alot to digest here (!) and i value you taking the time to comment. I think I'll look over my supplements and see what i can improve on there. I was completely dismissed by an Endocrinologist so sceptical of finding anyone who will listen- other than this forum. I just want to find balance!

greygoose profile image
greygoose in reply toPelotonRider

You're welcome. :)

doityourself profile image
doityourself

I can empathise with your position.I am hypothyroid, have taken hrt for over 20years. Also have Pernicious Anemia and asthma so as you can see plenty autoimmune issues!

They are all so inter related it's beyond my knowledge to understand how the issues that arise.

Looking at your results I do know from experience that your b12 is low especially as you are taking supplements. Have you been tested for Pernicious Anemia? Any test will be inaccurate atm due supplements you take, you'll need to stop taking for at least 3months to get an accurate indication of b12 levels.

Folate is often low with PA too.

Not sure if this is of any help.

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