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Metformin and reduced vitamin B12 levels: new advice for monitoring patients at risk

Update to the MHRA's view on Metformin and B12: [i]Metformin and reduced B12 levels: new advice for monitoring patients at risk Decreased vitamin B12 levels, or vitamin B12 deficiency, is now considered to be a common side effect in patients on metformin treatment, especially in those
Update to the MHRA's view on Metformin and B12: [i]Metformin and reduced B12 levels: new advice for monitoring patients at risk Decreased vitamin B12 levels, or vitamin B12 deficiency, is now considered to be a common side effect in patients on metformin treatment, especially in those
helvella profile image
helvella
in Pernicious Anaemia Society

Metformin and reduced vitamin B12 levels: new advice for monitoring patients at risk

Update to the MHRA's view on Metformin and B12: [i]Metformin and reduced B12 levels: new advice for monitoring patients at risk Decreased vitamin B12 levels, or vitamin B12 deficiency, is now considered to be a common side effect in patients on metformin treatment, especially in those
Update to the MHRA's view on Metformin and B12: [i]Metformin and reduced B12 levels: new advice for monitoring patients at risk Decreased vitamin B12 levels, or vitamin B12 deficiency, is now considered to be a common side effect in patients on metformin treatment, especially in those
helvella profile image
helvella
Administratorin Thyroid UK

Vitamin B12 help with CLL?

Dose vitamin B12 increase HAEMOGLOBIN.
Dose vitamin B12 increase HAEMOGLOBIN.
tms99532 profile image
tms99532
in CLL Support
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Mary70

One of the problems faced is that my then doctor discovered is that my vitamin b12 level was very low, and health wise, I was given a course of vitamin b12 injections.
One of the problems faced is that my then doctor discovered is that my vitamin b12 level was very low, and health wise, I was given a course of vitamin b12 injections.
mary70 profile image
mary70
in AF Association

Vitaminb12 shots

Hi I am lacking vitamin b12 and have my first jab on Wednesday my doctor said I need 5 shots. Once I’ve had these 5 will everything go back to normal ?
Hi I am lacking vitamin b12 and have my first jab on Wednesday my doctor said I need 5 shots. Once I’ve had these 5 will everything go back to normal ?
Tjp30 profile image
Tjp30
in Pernicious Anaemia Society

Vitamin b12 vitamin b9 anaemia

Hi everyone, i hope you are all doing well. I was diagnosed with pernicious anaemia in 2013 and was having B12 injections every month. A few years ago my GP surgery had a change in management and a new GP changed my injections to every 3 months. Last year i was having bloods done (for a different reason
Hi everyone, i hope you are all doing well. I was diagnosed with pernicious anaemia in 2013 and was having B12 injections every month. A few years ago my GP surgery had a change in management and a new GP changed my injections to every 3 months. Last year i was having bloods done (for a different reason
Amelia0710 profile image
Amelia0710
in Pernicious Anaemia Society

Test Results after discussion on here

Too much vitamin B12 in these individuals can lead to damage of the optic nerve, which might lead to blindness. Anyone who is allergic to cobalt should also avoid taking vitamin B12 - as the vitamin contains a significant amount of this element.
Too much vitamin B12 in these individuals can lead to damage of the optic nerve, which might lead to blindness. Anyone who is allergic to cobalt should also avoid taking vitamin B12 - as the vitamin contains a significant amount of this element.
CyclingDog profile image
CyclingDog
in Pernicious Anaemia Society

Thyroid antibodies update

Update from thyroid antibodies post..I had my bloods done off go...my vitamin b12 was 658. Folate. 20 seratin 31. TSH 2.3. Doc said all normal 😩
Update from thyroid antibodies post..I had my bloods done off go...my vitamin b12 was 658. Folate. 20 seratin 31. TSH 2.3. Doc said all normal 😩
geordieclaire120573 profile image
geordieclaire120573
in Thyroid UK

DU Suppression Test and B12

and Nevertheless, in clinical practice abnormal dU suppression serves as a sensitive index of the presence of megaloblastosis due to vitamin B12 or folate deficiency. dU suppression is also abnormal in a number of conditions other than vitamin B12 or folate deficiency, but its overall specificity in
and Nevertheless, in clinical practice abnormal dU suppression serves as a sensitive index of the presence of megaloblastosis due to vitamin B12 or folate deficiency. dU suppression is also abnormal in a number of conditions other than vitamin B12 or folate deficiency, but its overall specificity in
B12life profile image
B12life
in Pernicious Anaemia Society

Sjögren's syndrome: a potential new aetiology of mild cobalamin deficiency

This paper identifies the possibility of Sjögren's syndrome affecting ability to absorb vitamin B12. It is about twenty years old but I don't remember the issue being mentioned.
This paper identifies the possibility of Sjögren's syndrome affecting ability to absorb vitamin B12. It is about twenty years old but I don't remember the issue being mentioned.
helvella profile image
helvella
Administratorin Thyroid UK

Vitamin B12 liquid drops/sprays

I get injections every 3 months. Still constantly tired throughout. Has anoyone taken the liquid drops or nasal sprays whilst on injections?
I get injections every 3 months. Still constantly tired throughout. Has anoyone taken the liquid drops or nasal sprays whilst on injections?
Whin91 profile image
Whin91
in Pernicious Anaemia Society

What do you think about these results? Any suggestions will be appreciated. Feeling very tired.

TSH Analyte Value TSH 3.98 Reference Range: 0.40-4.50 mIU/L T4, FREE Analyte Value T4, FREE 1.1 Reference Range: 0.8-1.8 ng/dL T3, FREE Analyte Value T3, FREE 2.4 Reference Range: 2.3-4.2 pg/mL VITAMIN B12 Analyte Value VITAMIN B12 Performing Sites 441 Reference Range: 200-1100 pg/mL TP Quest
TSH Analyte Value TSH 3.98 Reference Range: 0.40-4.50 mIU/L T4, FREE Analyte Value T4, FREE 1.1 Reference Range: 0.8-1.8 ng/dL T3, FREE Analyte Value T3, FREE 2.4 Reference Range: 2.3-4.2 pg/mL VITAMIN B12 Analyte Value VITAMIN B12 Performing Sites 441 Reference Range: 200-1100 pg/mL TP Quest
lindaj54 profile image
lindaj54
in Thyroid UK

Weird science

Severe deficiency of Vitamin B12
Severe deficiency of Vitamin B12
Sallyannl profile image
Sallyannl
in Pernicious Anaemia Society

Rant + seeking help to manage RLS with home remedies

After running all blood tests and nerve conduction tests, I was told that I have really low Vitamin B12 levels and the doc said it doesn’t look like RLS. That something else could be triggering this. The doc put me on 100 mg gabantin and a supplement for my vitamin b12.
After running all blood tests and nerve conduction tests, I was told that I have really low Vitamin B12 levels and the doc said it doesn’t look like RLS. That something else could be triggering this. The doc put me on 100 mg gabantin and a supplement for my vitamin b12.
PrinkaRuds profile image
PrinkaRuds
in Restless Legs Syndrome

Has anyone got links between low vitamin b12 and endo?

I have more issues and have spoken to a different clinician in MSK who suggests my pins and needles in my arms are not my herniated disks in my neck (mri confirmed) but more than likely vitamin b12 deficiency which apparently!
I have more issues and have spoken to a different clinician in MSK who suggests my pins and needles in my arms are not my herniated disks in my neck (mri confirmed) but more than likely vitamin b12 deficiency which apparently!
Peppermints profile image
Peppermints
in Endometriosis UK

Canned Sardines: Are They Good for You?

https://www.webmd.com/diet/canned-sardines-good-for-you "A serving of four sardines contains: Calories: 100 Protein: 12 grams Fat: 5 grams Carbohydrates: 0 grams Fiber: 0 grams Sugar: 0 grams Sardines are an excellent source of these vitamins and minerals: Vitamin B12
https://www.webmd.com/diet/canned-sardines-good-for-you "A serving of four sardines contains: Calories: 100 Protein: 12 grams Fat: 5 grams Carbohydrates: 0 grams Fiber: 0 grams Sugar: 0 grams Sardines are an excellent source of these vitamins and minerals: Vitamin B12
Bolt_Upright profile image
Bolt_Upright
in Cure Parkinson's

Vitamin B12 affecting HCT ?

I have required 2 venesections within 3 weeks.(.47 and .48) RBC 6.79 I have started taking vitamin B12 drops (1ml daily) Has anyone else experienced a pronounced change in blood levels with Vitamin B12? Thankyou for any advice
I have required 2 venesections within 3 weeks.(.47 and .48) RBC 6.79 I have started taking vitamin B12 drops (1ml daily) Has anyone else experienced a pronounced change in blood levels with Vitamin B12? Thankyou for any advice
Bobadog profile image
Bobadog
in MPN Voice

Thoughts / help with New results since rise in Levo medication.

B12 - 562 ng/L {197 - 771} Serum folate - 2.5 ug/L {3 - 20) 22/11/21 results Serum TSH level - 2.45 mIU/L {0.27 - 4.2} Serum free T4 level - 17.9 pmol/L {11.0 - 21.2} Serum free T3 level - 3.5 pmol/L {3.1 - 6.8} Serum vitamin B12 - 385 ng/L {197 - 771} Serum folate - 6.4 ug/L {3 - 20)
B12 - 562 ng/L {197 - 771} Serum folate - 2.5 ug/L {3 - 20) 22/11/21 results Serum TSH level - 2.45 mIU/L {0.27 - 4.2} Serum free T4 level - 17.9 pmol/L {11.0 - 21.2} Serum free T3 level - 3.5 pmol/L {3.1 - 6.8} Serum vitamin B12 - 385 ng/L {197 - 771} Serum folate - 6.4 ug/L {3 - 20)
debra135 profile image
debra135
in Thyroid UK

Folate, Vitamin B12, Homocysteine, Hypermethylation of tumor suppressor genes, etc.

My warnings go back ~14 years, but only 6 years here, starting with: https://healthunlocked.com/advanced-prostate-cancer/posts/133412870/circulating-folate-and-vitamin-b12-and-pca-risk "Circulating Folate and B12 and PCa Risk" Since then, there have been numerous related threads.
My warnings go back ~14 years, but only 6 years here, starting with: https://healthunlocked.com/advanced-prostate-cancer/posts/133412870/circulating-folate-and-vitamin-b12-and-pca-risk "Circulating Folate and B12 and PCa Risk" Since then, there have been numerous related threads.
pjoshea13 profile image
pjoshea13
in Advanced Prostate Cancer

Vitamin B12

Hi, I’ve started taking vitamin B12 as my blood test shows normal but low. Only problem is, my ur8ne has turned bright yellow - does this mean I’m taking too much?
Hi, I’ve started taking vitamin B12 as my blood test shows normal but low. Only problem is, my ur8ne has turned bright yellow - does this mean I’m taking too much?
Essexlil profile image
Essexlil
in Thyroid UK
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