Blood Results Antibodies Positive..Any Help or Guidance?

[Kim327]

Below are my lab results. Diagnosed Graves Disease February 2019. Off thyroid medication. Feel awful. Pain left side of my head, shoulder, arm, hip and thigh. Itchy eyebrows. Also flush cheeks. Have deviated septum and possible TMJ.

Recently put on estrogen patch. Been a year of feeling sick. Why if my thyroid levels are normal am I still so sick and in pain all the time?

Primary care referred me to Rheumatologist. I have young kids and I have no life in me to get going every day.

Any help or thoughts are GREATLY Appreciated!!

(*)mean abnormal-

RF SCREEN QL<14 (<14) rheumatoid factor, screen, qualitative

TSH1.42u[iU]/mL(0.40-4.50) thyroid stimulating hormone, serum

ANTI-DS-DNA<1 (< = 4 Ne) anti double stranded DNA

HYAL CAST URNone Seen/[LPF](None Seen) hyaline casts, urine

BACTURMICRONone Seen /hpf/[HPF](None Seen) bacteria, urine, microscopic

EPITH CELL UNone Seen /hpf/[HPF](<or=5) epithelial cells, squamous, urine

RBCS MICRO UNone Seen (<or=2) RBC urine by microscopy

WBC BLOODNone Seen /hpf10*9/L(<or=5) leukocyte (white blood cells) count, blood

WBC ESTERASENegative (Negative) leukocyte (WBC) esterase, urine

NITRITE UANegative (Negative) Nitrite Urine

TOT PROT URNegative (Negative) Protein [Mass] in Urine collected for unspecified duration

BLOOD URNegative (Negative) BLOOD, URINE (hematuria)

KETONES URNegative (Negative) KETONES, URINE

BILIRUBIN URNegative (Negative) bilirubin, urine

GLUCOSE, URNNegative (Negative) glucose, urine, semiquantitative

PH URINE6.5 (5.0-8.0) pH, urine, semiquantitative

SPEC GR URIN1.006 (1.001-1.035) specific gravity, urine

APPEARANCE UClear (Clear) appearance, urine

UA COLORYellow (Yellow) urine color

T3FREE280pg/dLUnits converted. See lab report for original value. T3 (triiodothyronine), free

SSA<1.0 (<1.0) Sjogren's syndrome-A, extractable nuclear Ab, serum

THYROGLB AB<1 IU/mL (<= 1) thyroglobulin antibody

URINE CULTFINAL urine culture

LYME IGG WB<0.90 B. Burgdorferi IgG Antibody by Western Blot

* ANAAC-1 Aantinuclear antibody

* ANACHOICEPositive (Negative)AANA Choice Screen

CRP0.02mg/dLUnits converted. See lab report for original value. C-reactive protein, serum

FOLATE12.9ng/mL(> 5.4) folate, serum

B-12664pg/mL(200-1100) B-12, serum

T4, FREE1.0ng/dL(0.8-1.8) thyroxine, serum, free

FERRITIN98ng/mL(16-232) ferritin, serum

LIPASE21U/L(7-60) lipase, serum

AMYLASE44U/L(21-101) amylase, serum

MAGNESIUM2.2mg/dL(1.5-2.5) magnesium, serum

* CHOLESTEROL223mg/dL(<200)HCholesterol [Mass/volume] in Serum or Plasma - mg/dL

ESR9 (?)mm/h(<30)Nerythrocyte sedimentation rate

EGFR IF AFA108 (?)mL/min/1.73m2(>=60) eGFR if African American

SGPT (ALT)15U/L(6-29) alanine aminotransferase (SGPT), serum

SGOT (AST)14U/L(10-35) aspartate aminotransferase (SGOT), serum

ALK PHOS51U/L(33-115) alkaline phosphatase, serum

BILI TOTAL1.2mg/dL(0.2-1.2) bilirubin, serum, total

A/G RATIO2.0 (calc) (1.0-2.5) albumin/globulin ratio, serum

GLOBULIN TOT2.2 (?)g/dL(1.9-3.7) globulins, serum, total

ALBUMIN4.5g/dL(3.6-5.1) albumin, serum

PROTEIN, TOT6.7g/dL(6.1-8.1) protein, total, serum

CALCIUM9.4mg/dL(8.6-10.2) calcium, serum

BUN/CREATNOTE (calc) (6-22) urea nitrogen/creatinine ratio, serum

CREATININE0.76mg/dL(0.50-1.10) creatinine, serum

BUN18mg/dL(7-25) urea nitrogen, blood

CO2 TOTAL29mmol/L(20-32) carbon dioxide, serum, total

CHLORIDE102mmol/L(98-110) chloride, serum

POTASSIUM4.4mmol/L(3.5-5.3) potassium, serum

SODIUM139mmol/L(135-146) sodium, serum

GLUCOSE SER100mg/dL(65-139) blood glucose

BASOPH COUNT31 CELLS/UL10*3/mm3(0-200) basophil count, blood

EOSINPABSMAN68{Cells}/uL(15-500) eosinophils, absolute, manual

ABS MONOS477{Cells}/uL(200-950) Absolute Monocyte count

LYMPH COUNT1569 CELLS/UL10*3/mm3(850-3900) lymphocyte count, blood

NEUTROPHILS#4055 cells/uL (1500-7800) neutrophil count, absolute

BASOPHIL %0.5%(0-2) basophils as percent of blood leukocytes

EOSINOPHIL %1.1%(0-8) eosinophils as percent of blood leukocytes

MONOCYTE %7.7%(0-13) monocytes as percent of blood leukocytes

LYMPHS %25.3%(15-49) lymphocytes as percent of blood leukocytes

PMN %65.4%(38-80) neutrophils as percent of blood leukocytes

MPV11.3fL(7.5-12.5) mean platelet volume

PLATELETS234 (?)10*3/mm3(140-400) platelet count

RDW11.8%(11.0-15.0) red blood cell distribution width

MCHC RBC33.9g/dL(32.0-36.0) mean corpuscular hemoglobin concentration, RBC

MCH32.4pg(27.0-33.0) mean corpuscular hemoglobin, RBC

MCV95.5fL(80.0-100.0) mean corpuscular volume, RBC

HCT42.2%(35.0-45.0) hematocrit, blood

HGB14.3g/dL(11.7-15.5) hemoglobin, blood

RBC4.42 MILLION/UL10*6/mm3(3.80-5.10) erythrocyte (RBC) count

WBC6.2 (?)10*3/mm3(3.8-10.8) leukocyte count, blood

[Angel_of_the_North]

Image is far too small to read. Need full FT3 results with range. Free T4 is pretty low in range. TG antibodies are negative and I don't see a result for TPO or TRab or TSI. Can't see any positive antibodies at all. Did you definitely have positive TRab when Graves was diagnosed?

[Kim327 in reply to Angel_of_the_North]

Hi!

Anti-TPO was 752 H <35 IU/mL on 4/18/19

Anti-TPO was 7774 H <35 IU/mL on 3/11/19

TSI 2.40. <0.56 IU/L on 4/18/19

TSI. 2.93 On 3/11/19

States abnormal range for patients with hyperthyroid Graves is <0.55 IU/L

[Kim327 in reply to Angel_of_the_North]

Also this was my primary car doctor.

Did tests with ENDO prior

December 2019

TSH 2.3

T3 36.8. (27-41)

T4. 7. (4.5-11.7)

October 2019

3.19 (0.234-4.020)

T3. 2.8. (2.0-4.7). Pg/ml

T4. 0.96 (0.80-1.73) ng/pl

[Batty1]

Hi Kim, I can totally relate to what your going through and no your not losing your mind.

[Kim327 in reply to Batty1]

Thank you !!!!!

[SlowDragon Administrator]

We see many early stage Hashimoto's patients misdiagnosed as Graves' disease

You need TPO and TG antibodies tested for Hashimoto's (and Graves)

And TSI or TRab antibodies tested for Graves

thyroiduk.org.uk/tuk/about_...

No vitamin D result

TSH, Ft3 and FT4 need testing together

High cholesterol is linked to being hypothyroid (Hashimoto's)

Are you on strictly gluten free diet or tried it

While still eating high gluten diet ask GP for coeliac blood test first or buy test online for under £20, just to rule it out first

Assuming test is negative you can immediately go on strictly gluten free diet




(If test is positive you will need to remain on high gluten diet until endoscopy, maximum 6 weeks wait officially)




Trying gluten free diet for 3-6 months. If no noticeable improvement then reintroduce gluten and see if symptoms get worse

chriskresser.com/the-gluten...

amymyersmd.com/2018/04/3-re...

thyroidpharmacist.com/artic...

drknews.com/changing-your-d...

restartmed.com/hashimotos-g...

[Kim327 in reply to SlowDragon]

Hi

The recent tests are from my Primary Care doctor.

ENDO did vitamin D in December and it was 60 (30-100)

My B12 is always super high. Was taking just B 12 and now taking a B complex instead

Did Gluten free, dairy free you name it! Stopped and started gluten because lost too much weight. Scary weight loss.

Had an endoscopy

All normal results just have gastritis now they say due to reflux and on Dexilant 60 mg a day

When diagnosed with Graves :

Anti-TPO was 752 H <35 IU/mL on 4/18/19

Anti-TPO was 7774 H <35 IU/mL on 3/11/19

TSI 2.40. <0.56 IU/L on 4/18/19

TSI. 2.93 On 3/11/19

Paperwork say abnormal range for patients with hyperthyroid Graves is <0.55 IU/L

Thank you!

[SlowDragon Administrator in reply to Kim327]

So high TSI confirms Graves

Very high TPo suggests you might have Hashimoto's at same time

It's possible to have Graves and Hashimoto's together. Usually more complex to deal with. Treatment can be Block (with carbimazole) and replace with Levothyroxine

What about ferritin test result?

Have you had cholesterol tested?

[Kim327 in reply to SlowDragon]

i did not know you could have both Graves and Hashi!

FERRITIN 98ng/mL(16-232) ferritin, serum

And cholesterol is high 223 (<200)

High cholesterol is genetic all my sisters and mom have it. I’m in the peri menopause/ menopause phase which they all got high cholesterol and on medication. My doctor wants me to hold off on taking anything for cholesterol.

Thank you!

[Wetsuiter]

Have your mum & sisters had thyroid checks?

[Kim327 in reply to Wetsuiter]

Yes they are all normal

[Wetsuiter in reply to Kim327]

'normal' ?

catch all used by the medical profession, that could mean anything