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PCa-specific Survival after Radical Prostatectomy Is Improved by Metformin but not other Antidiabetic Drugs
New study from Finland below [1]. "Only postdiagnostic metformin use was associated with reduced risks of PCa death {53% reduction} and ADT initiation compared with nonusers." While Metformin users would be predominantly diabetic, it looks as though "nonusers" inxlude non-diabetics. "insulin and insulin
New study from Finland below [1]. "Only postdiagnostic metformin use was associated with reduced risks of PCa death {53% reduction} and ADT initiation compared with nonusers." While Metformin users would be predominantly diabetic, it looks as though "nonusers" inxlude non-diabetics. "insulin and insulin
pjoshea13
in
Advanced Prostate Cancer
3 years ago
Introduction
Hi. I was diagnosed with breast cancer in September, 2016. It has metastasized to my bones. I am following the protocol in the book, “How to Starve Cancer without Starving Yourself”. One of my MDs is prescribing drugs off-label. Consequently, I am taking Celebrex to reduce cancer inflammation, Metformin
Hi. I was diagnosed with breast cancer in September, 2016. It has metastasized to my bones. I am following the protocol in the book, “How to Starve Cancer without Starving Yourself”. One of my MDs is prescribing drugs off-label. Consequently, I am taking Celebrex to reduce cancer inflammation, Metformin
Jubilee1874
in
SHARE Metastatic Breast Cancer
3 years ago
Angiotensin Ⅱ Receptor Blockers
A new paper in the Japanese Journal of Cancer and Chemotherapy, below, [1]. "The use of anti-hypertensive drugs was reportedly associated with an increasing risk of Pca. However, as an effect of post diagnostic use of anti-hypertensive drugs, angiotensin Ⅱ receptor blockers(
[i][u]ARBs)was associated
A new paper in the Japanese Journal of Cancer and Chemotherapy, below, [1]. "The use of anti-hypertensive drugs was reportedly associated with an increasing risk of Pca. However, as an effect of post diagnostic use of anti-hypertensive drugs, angiotensin Ⅱ receptor blockers(
[i][u]ARBs)was associated
pjoshea13
in
Advanced Prostate Cancer
3 years ago
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U-Shaped PCa Risk - Metformin (& Warfarin & Vitamin D).
A new Israeli Metformin study below [1] "With 666,553 person-years follow-up, 1,592 men were diagnosed with prostate cancer. Metformin exposure in the previous year was positively associated with prostate cancer risk ..." "However, exposure in the previous 2-7 years was negatively associated with risk
A new Israeli Metformin study below [1] "With 666,553 person-years follow-up, 1,592 men were diagnosed with prostate cancer. Metformin exposure in the previous year was positively associated with prostate cancer risk ..." "However, exposure in the previous 2-7 years was negatively associated with risk
pjoshea13
in
Advanced Prostate Cancer
3 years ago
New here. My story.
In late November 2021, I was diagnosed with advanced Prostate Cancer. My PCa is believed to have metastasized to three lymph nodes (lower neck, diaphragm and lower back). I say “believed” because the metastasis has not been confirmed. My Gleason scores were all 9’s and 10’s. My oncologist and Urologist
In late November 2021, I was diagnosed with advanced Prostate Cancer. My PCa is believed to have metastasized to three lymph nodes (lower neck, diaphragm and lower back). I say “believed” because the metastasis has not been confirmed. My Gleason scores were all 9’s and 10’s. My oncologist and Urologist
Skipper238
in
Advanced Prostate Cancer
3 years ago
Ozempic
I have Type 2 Diabetes and the beginning of Stage 4 Kidney Disease. My endocrinologist just took me off Metformin to try Ozempic. Has anyone with kidney problems taken Ozempic? Has it helped the kidneys or just diabetes?
I have Type 2 Diabetes and the beginning of Stage 4 Kidney Disease. My endocrinologist just took me off Metformin to try Ozempic. Has anyone with kidney problems taken Ozempic? Has it helped the kidneys or just diabetes?
Jh51543
in
Kidney Disease
3 years ago
... and relax (hopefully)!
Long story ahead! It’s been a few weeks of ‘things’. In early November hubby complained his head was sore, which can mean all sorts since his stroke and not always being able to explain very well. Two days later he had a cluster of little blisters by his eye - shingles. A course of Aciclovar stopped
Long story ahead! It’s been a few weeks of ‘things’. In early November hubby complained his head was sore, which can mean all sorts since his stroke and not always being able to explain very well. Two days later he had a cluster of little blisters by his eye - shingles. A course of Aciclovar stopped
Janma123
in
British Heart Foundation
3 years ago
Where to turn next? 4th transfer - BFN
Hi ladies, I’ve been absent on here whilst I went through for my fourth transfer. I’ve learnt today that this transfer has failed. Can anyone offer any additional advice on what to try next as I don’t feel I can keep going? 1st transfer - 5AB - BFN - spotting and period before OTD - added in Lubion
Hi ladies, I’ve been absent on here whilst I went through for my fourth transfer. I’ve learnt today that this transfer has failed. Can anyone offer any additional advice on what to try next as I don’t feel I can keep going? 1st transfer - 5AB - BFN - spotting and period before OTD - added in Lubion
strawberriesandcream
in
Fertility Network UK
3 years ago
Looking for the best supplement for pcos ?
Look no further , are you struggling on metformin ? , just taking Myo inositol ? Or maybe your not taking anything for your insulin resistance ? Let me introduce you to my lil friend, Inositol is a brilliant supplement. Inositol influences the action of insulin, a hormone essential for blood sugar control
Look no further , are you struggling on metformin ? , just taking Myo inositol ? Or maybe your not taking anything for your insulin resistance ? Let me introduce you to my lil friend, Inositol is a brilliant supplement. Inositol influences the action of insulin, a hormone essential for blood sugar control
Carly93
in
PCOS UK (Verity)
3 years ago
3 noises!
Hello, wonder if anyone can help me. I am dealing with a bout of tinnitus at the moment which seems very odd. As a quick summary Left ear - constant hissing sound Right ear noise 1 - low pitched whine Right ear noise 2 - broken sound like a hard drive being written to (if you have ever heard such like
Hello, wonder if anyone can help me. I am dealing with a bout of tinnitus at the moment which seems very odd. As a quick summary Left ear - constant hissing sound Right ear noise 1 - low pitched whine Right ear noise 2 - broken sound like a hard drive being written to (if you have ever heard such like
boilingbogwo
in
Tinnitus UK
3 years ago
Mucus and blood
Has anyone had consolation with mucus and then a normal bowel movement about an hour later? I wiped the 2nd time and there was mucus but bowel was soft. I have a colonoscopy in a couple of months and I am diabetic. Started out constipation with white mucus. Then weeks later held poop and when I
Has anyone had consolation with mucus and then a normal bowel movement about an hour later? I wiped the 2nd time and there was mucus but bowel was soft. I have a colonoscopy in a couple of months and I am diabetic. Started out constipation with white mucus. Then weeks later held poop and when I
Lor11111
in
Colon Cancer Connected
3 years ago
I feel like banging my head against a wall but that could make things worse.
Well thats one hell of a title, dont worry i dont mean to bang my head against anything . Right this may not be bi related but maybe its. Enough mystery so here goes. Quite a few years ago i was diagnosed with type 2 diabetes ( stay with me it may get bi relevant) after even more years being borderline
Well thats one hell of a title, dont worry i dont mean to bang my head against anything . Right this may not be bi related but maybe its. Enough mystery so here goes. Quite a few years ago i was diagnosed with type 2 diabetes ( stay with me it may get bi relevant) after even more years being borderline
paxo05
in
Headway
3 years ago
Tinnitus and metformin
Hello, I have had tinnitus in the form of a hissing sound in both ears since January 2020. I thought I was coping with it OK, it had essentially become background noise but in the past 5 weeks it has gotten considerably louder which coincides with taking metform for diabetes at two tablets per day, prior
Hello, I have had tinnitus in the form of a hissing sound in both ears since January 2020. I thought I was coping with it OK, it had essentially become background noise but in the past 5 weeks it has gotten considerably louder which coincides with taking metform for diabetes at two tablets per day, prior
boilingbogwo
in
Tinnitus UK
3 years ago
One Year Post Diagnosis
I was diagnosed with Stage 4 ductal adenocarcinoma of the prostate in late October 2020. After initially being on Eligard for 4 months my PSA had dropped to around 2.0, and the Oncologist was happy. My next PSA test after a further 4 months which included a continuation of Eligard and 25 radiation treatments
I was diagnosed with Stage 4 ductal adenocarcinoma of the prostate in late October 2020. After initially being on Eligard for 4 months my PSA had dropped to around 2.0, and the Oncologist was happy. My next PSA test after a further 4 months which included a continuation of Eligard and 25 radiation treatments
TottenhamMan
in
Advanced Prostate Cancer
3 years ago
Concerned about husband diabetic type 2
My husband is diabetic overweight and smoker, he was on metformin 1000g , now on double the dose and has another tab added called dapaglifloxin 10mg , but when doing the urine dip test the colour on test strip is dark brown, so is in effect showing too much sugar, around two weeks before taking this
My husband is diabetic overweight and smoker, he was on metformin 1000g , now on double the dose and has another tab added called dapaglifloxin 10mg , but when doing the urine dip test the colour on test strip is dark brown, so is in effect showing too much sugar, around two weeks before taking this
Eternity6
in
Diabetes Research & Wellness Foundation
3 years ago
Worried about husband type 2 diabetic
My husband is on metformin and has now had it increased to 2000 mg daily with another tab now included called for Dapagliflozin 10mg, but when he’s using the urine dipstick the colour is dark brown which indicates far too much sugar, he’s been passing blood for three weeks and was given antibiotics for
My husband is on metformin and has now had it increased to 2000 mg daily with another tab now included called for Dapagliflozin 10mg, but when he’s using the urine dipstick the colour is dark brown which indicates far too much sugar, he’s been passing blood for three weeks and was given antibiotics for
Eternity6
in
Pregnancy and Parenting Support
3 years ago
Raised liver enzymes
I had a total thyroidectomy following it being enlarged and covered in cysts in August 2018 - blood tests also showed my thyroid levels were falling out of range. This followed a partial thyroidectomy for the same reason in 1994. 10 months after the 2018 surgery, so by mid 2019, my thyroid levels balanced
I had a total thyroidectomy following it being enlarged and covered in cysts in August 2018 - blood tests also showed my thyroid levels were falling out of range. This followed a partial thyroidectomy for the same reason in 1994. 10 months after the 2018 surgery, so by mid 2019, my thyroid levels balanced
pinkpixie
in
Thyroid UK
3 years ago
The Impact of Metformin Use with Survival Outcomes.
New meta-analysis below [1]. "27 eligible studies were identified, including 123,212 participants. "In prostate cancer, patients using metformin have significant benefits for: ... recurrence (HR = 0.74 ...), ...{cancer-specific survival} (HR = 0.74 ...), and ... {overall survival} (HR = 0.76 ...).
New meta-analysis below [1]. "27 eligible studies were identified, including 123,212 participants. "In prostate cancer, patients using metformin have significant benefits for: ... recurrence (HR = 0.74 ...), ...{cancer-specific survival} (HR = 0.74 ...), and ... {overall survival} (HR = 0.76 ...).
pjoshea13
in
Advanced Prostate Cancer
3 years ago
blood sugar control
having trouble controlling after breakfast bs spikes. Take metformin and glimepiride but am spikes frequently around 215. Any suggestions?? Last a1c was 6.3 so overall bs has improved.
having trouble controlling after breakfast bs spikes. Take metformin and glimepiride but am spikes frequently around 215. Any suggestions?? Last a1c was 6.3 so overall bs has improved.
mickeyba1
in
Kidney Disease
3 years ago
Are you on ADT? Many/Most of us are. THIS IS A MUST WATCH VIDEO. 3 key points: Statins, Degelrix, Metformin. Grand Rounds in Urology.Mike
https://youtu.be/6duRbpY-WkI
https://youtu.be/6duRbpY-WkI
Spyder54
in
Advanced Prostate Cancer
3 years ago
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