What is consensus on fenbendazole and metformin in terms of treating prostate cancer as of 2021?

[FiguringOut]

Gleason 4+3, PSA 7.8, T2C M59 (my father).

Looking for different ways to treat his prostate cancer including non-orthodox like Fenbendazole and metformin.

What evidence we have as of 2021 to efficacy of these treatments?

Even if anecdotal?

[NPfisherman]

Welcome to the forum,

There is a definitive study on metformin going on that is STAMPEDE- ArmK. This trial compares SOC + metformin vs SOC and concludes in 2024.

Care Oncology (COC) has chosen to use mebendazole and the information is listed below:

careoncology.com/mebendazol...

I think the liver function argument is a good point along with the safe for humans argument.

You may wish to look at IV Vitanmin C and sulfasalazine (generic rheumatoid arthritis drug) since you are looking for non SOC--see below:

pubmed.ncbi.nlm.nih.gov/316...

Best of luck on your journey...

Don Pescado