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[Fentanyl effects on glutamate and GABA release rates from anterior hypothalamus] and [Fentanyl inhibits GABAergic neurotransmission]
A week ago I had surgery under general anesthesia. I was given propofol and fentanyl. My neuromuscular function has worsened. I've had propofol before without problems. What happened this time? I suspect fentanyl inhibition of GABA progressed my ALS. The NMDA receptor and the gamma-aminobutyric acid
A week ago I had surgery under general anesthesia. I was given propofol and fentanyl. My neuromuscular function has worsened. I've had propofol before without problems. What happened this time? I suspect fentanyl inhibition of GABA progressed my ALS. The NMDA receptor and the gamma-aminobutyric acid
SilentEchoes
in
Cure Parkinson's
2 years ago
Natural relief for opioid constipation
Hi, like many of us I suffer with really bad constipation as the result of taking opioids. I take morphine and it successfully controls my RLS but the GI side effects are awful. Currently I am taking Laxido but would prefer to manage the constipation naturally long term if possible. I already have
Hi, like many of us I suffer with really bad constipation as the result of taking opioids. I take morphine and it successfully controls my RLS but the GI side effects are awful. Currently I am taking Laxido but would prefer to manage the constipation naturally long term if possible. I already have
Jumpey
in
Restless Legs Syndrome
2 years ago
Petition to grant visas to Ukrainian refugees
Please sign and share if you agree https://petition.parliament.uk/petitions/609530 I’m so ashamed of the Home Office’s inhumanity towards these exhausted and traumatised people Ps: a report from Mark Easton, the BBC’s Home Editor in Calais: “On Monday, one family followed by the BBC was sent from building
Please sign and share if you agree https://petition.parliament.uk/petitions/609530 I’m so ashamed of the Home Office’s inhumanity towards these exhausted and traumatised people Ps: a report from Mark Easton, the BBC’s Home Editor in Calais: “On Monday, one family followed by the BBC was sent from building
Hidden
in
Lung Conditions Community Forum
2 years ago
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Hydro after meningitis
Has anyone experienced hydrocephalus after recovering from meningitis?How long after recovering was you diagnosed with it or showed symptoms? My 5 month old had pneumococcal meningitis we are now 6 weeks on since being diagnosed, he had an burr hole surgery as they thought he had pockets of puss on brain
Has anyone experienced hydrocephalus after recovering from meningitis?How long after recovering was you diagnosed with it or showed symptoms? My 5 month old had pneumococcal meningitis we are now 6 weeks on since being diagnosed, he had an burr hole surgery as they thought he had pockets of puss on brain
Craze2022
in
Meningitis Now
2 years ago
What is AMX0035, and Why Is It Important for All of Us?
AMX0035 is a drug combination of sodium phenylbutyrate (PB) and tauroursodeoxycholic acid (TUDCA). It works by regulating the mitochondrial (cell power supply) and endoplasmic reticulum (quality control centers). Put simply, both processes should work in unison, but when they don’t, cells in the body
AMX0035 is a drug combination of sodium phenylbutyrate (PB) and tauroursodeoxycholic acid (TUDCA). It works by regulating the mitochondrial (cell power supply) and endoplasmic reticulum (quality control centers). Put simply, both processes should work in unison, but when they don’t, cells in the body
SilentEchoes
in
Cure Parkinson's
2 years ago
Besremi -Six Week Update
I had another CMP and CBC yesterday. Background: I got my first Besremi shot on January 28. I asked to start at 50 mcg. Second shot was 60 mcg and third was 70mcg. After six weeks, I'm thrilled to see changes in my counts: My WBC went from 15 to 10.8 (while it can fluctuate, it doesn't have a drop
I had another CMP and CBC yesterday. Background: I got my first Besremi shot on January 28. I asked to start at 50 mcg. Second shot was 60 mcg and third was 70mcg. After six weeks, I'm thrilled to see changes in my counts: My WBC went from 15 to 10.8 (while it can fluctuate, it doesn't have a drop
Elizka
in
MPN Voice
2 years ago
Cryoablation and Flutter procure : Diary Day of Procedure
Hi all Hopefully this won’t bore you all but seeings how you guys have been so great to me over the last 10 months since I found out I had AF and a flutter I thought I would share my experience of the procedure . So March 3rd ,9.30am at St Barts and I’m already sitting outside the lab waiting to go
Hi all Hopefully this won’t bore you all but seeings how you guys have been so great to me over the last 10 months since I found out I had AF and a flutter I thought I would share my experience of the procedure . So March 3rd ,9.30am at St Barts and I’m already sitting outside the lab waiting to go
mjm1971
in
AF Association
2 years ago
Niacin, NR, NMN, NAD+,NADH: what is the effect on mitochondria and is it beneficial to PD?
I’m working on understanding the process by which niacin ultimately increases NAD and if supplementing with NMN, a more immediate precursor is more advantageous or perhaps NADH is better?
I’m working on understanding the process by which niacin ultimately increases NAD and if supplementing with NMN, a more immediate precursor is more advantageous or perhaps NADH is better?
Hidden
in
Cure Parkinson's
2 years ago
Phlebotomies keeping HCT at great level!
Hi My Friends! I have been having phlebotomies every few weeks. It varies depending on my HCT level. I am taking a very low dose of HU; 500mg 4 time a week. I had been up to 1500 mg daily and I just could not tolerate it. HU alone was not getting my HCT below 45 and seems to have very little influence
Hi My Friends! I have been having phlebotomies every few weeks. It varies depending on my HCT level. I am taking a very low dose of HU; 500mg 4 time a week. I had been up to 1500 mg daily and I just could not tolerate it. HU alone was not getting my HCT below 45 and seems to have very little influence
Wewo01
in
MPN Voice
2 years ago
Stories from a Hospital volunteer - "From major to minor"
Monday 6th December As some of you know, I occasionally write up a story or two from my Volunteering at a London Hospital, my role being a “Ward Musician.” But in Covid times I'm restricted to the use of a Blue-tooth speaker and the use of the Spotify App to search for patients’ musical requests. But
Monday 6th December As some of you know, I occasionally write up a story or two from my Volunteering at a London Hospital, my role being a “Ward Musician.” But in Covid times I'm restricted to the use of a Blue-tooth speaker and the use of the Spotify App to search for patients’ musical requests. But
Greenthorn
in
Lung Conditions Community Forum
3 years ago
Agony with prontogest injections...is that normal??
I have been on these for just over a week and am having them every other day. Yesterday a new person (ex nurse) did it and I have been in AGONY since yesterday evening. The pain was so excruciating during the night that I couldn't sleep. Less painful now but still hurts a lot every time I move (been
I have been on these for just over a week and am having them every other day. Yesterday a new person (ex nurse) did it and I have been in AGONY since yesterday evening. The pain was so excruciating during the night that I couldn't sleep. Less painful now but still hurts a lot every time I move (been
SimsB
in
Fertility Network UK
2 years ago
An long overdue update - baby Eliza arrived 16-2-22.
Hi sorry this has taken me so long to do. I had lots of replies and support during my pregnancy. I was induced at 39 weeks mainly due to her size being so big and I was worried about complications that are associated with bigger sized babies . I know people say growth scans aren’t always accurate- in
Hi sorry this has taken me so long to do. I had lots of replies and support during my pregnancy. I was induced at 39 weeks mainly due to her size being so big and I was worried about complications that are associated with bigger sized babies . I know people say growth scans aren’t always accurate- in
Jess1981
in
Pregnancy and Parenting Support
2 years ago
High anxiety and emotional
Hi guys, started taking my meds on Tuesday for my FET. 6mg of prognova and buserelin. Today I am so emotional and my anxiety is through the roof. I feel very sensitive. I know bloating is a side effect (I have awful bloating) but are these feelings from the meds do you think or just me? Did they make
Hi guys, started taking my meds on Tuesday for my FET. 6mg of prognova and buserelin. Today I am so emotional and my anxiety is through the roof. I feel very sensitive. I know bloating is a side effect (I have awful bloating) but are these feelings from the meds do you think or just me? Did they make
Littlepeax
in
Fertility Network UK
2 years ago
How long to wait for a tracheotomy
Hello. So my brother has been weaned off sedation abit. However he has been becoming distressed- not surprising as he has a tube down his throat and the nurses have told him where he is. He is still not fully unsedated - his partner is struggling as she showed him a picture of their daughter but he was
Hello. So my brother has been weaned off sedation abit. However he has been becoming distressed- not surprising as he has a tube down his throat and the nurses have told him where he is. He is still not fully unsedated - his partner is struggling as she showed him a picture of their daughter but he was
paris2021
in
ICUsteps
3 years ago
Extreme Dizziness and shaking.
Got up from the settee last night and had a really bad dizzy spell which lasted for an hour and came in waves of shaking and extreme panic and unable to walk for fear of falling down. Settled down and feel normal this morning. Phoned for ambulance then cancelled when I felt better. Tested positive for
Got up from the settee last night and had a really bad dizzy spell which lasted for an hour and came in waves of shaking and extreme panic and unable to walk for fear of falling down. Settled down and feel normal this morning. Phoned for ambulance then cancelled when I felt better. Tested positive for
Cazdud
in
NRAS
3 years ago
Brother due a tracheostomy
Hi. So update is that my brother is due a tracheostomy but will have to be last in theatre as he is in a covid ward. Apparently one of the nurses slightly reduced his sedation and he was following her around the room with his eyes. She then put his partner on the phone and she was talking to him and
Hi. So update is that my brother is due a tracheostomy but will have to be last in theatre as he is in a covid ward. Apparently one of the nurses slightly reduced his sedation and he was following her around the room with his eyes. She then put his partner on the phone and she was talking to him and
paris2021
in
ICUsteps
3 years ago
2.9 year old granddaughter withholding
2.9 year old granddaughter withholding Hi, I’m extremely worried about my granddaughter and her ability to withhold her poo. She’s been doing this for at least 9 months. She’s been on 6/8 movical and 6 ml of picosulphate for 9 weeks and still manages to withhold daily. We believe she’s impacted which
2.9 year old granddaughter withholding Hi, I’m extremely worried about my granddaughter and her ability to withhold her poo. She’s been doing this for at least 9 months. She’s been on 6/8 movical and 6 ml of picosulphate for 9 weeks and still manages to withhold daily. We believe she’s impacted which
Scoob123
in
ERIC
2 years ago
CATCH-UP CORNER. WEEK 3. Come on in, everyone is welcome here ...
Hello fellow runners. A very warm welcome to the Corner, on what is a very blustery day here in the Staffs Moorlands! The weather is very changeable and currently we are , seemingly, in for a few boisterous days. But I have made up the fire and drawn up the chairs, so that we may share our running
Hello fellow runners. A very warm welcome to the Corner, on what is a very blustery day here in the Staffs Moorlands! The weather is very changeable and currently we are , seemingly, in for a few boisterous days. But I have made up the fire and drawn up the chairs, so that we may share our running
Oldfloss
Administrator
in
Couch to 5K
2 years ago
Suffering Fecal Incontinence Problem
My father is suffering from Tb Meningitis.His treatment is going for 8 months now.. All Symptoms are recovering But He's having Fecal Incontinence very much,problems to control pee and poop both. What to do? How much time it takes to recover? And is it serious?
My father is suffering from Tb Meningitis.His treatment is going for 8 months now.. All Symptoms are recovering But He's having Fecal Incontinence very much,problems to control pee and poop both. What to do? How much time it takes to recover? And is it serious?
Peacock12
in
Meningitis Now
2 years ago
Brain injury and seizures
Hi everyone. Not posted for quite a while! I hope everyone is good! I am struggling abit at the moment Aquired brain injury in 2019 Have been having seizures which doctors say is caused by gliosis (scar tissue in brain Was started on keppra weened off this, now taking lamotrigine Has anyone else
Hi everyone. Not posted for quite a while! I hope everyone is good! I am struggling abit at the moment Aquired brain injury in 2019 Have been having seizures which doctors say is caused by gliosis (scar tissue in brain Was started on keppra weened off this, now taking lamotrigine Has anyone else
Charlie90
in
Headway
2 years ago
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