Blood test results in full. Can anyone find a cause in there for my continued fatigue etc?

[DandyButch]

I still have the same symptoms, although some have improved a bit, but not gone, by any means. Still housebound.

I list below Blood test results. Can anyone suggest an issue that may cause my symptoms because my GP says no action, normal.

Serum 25 - HO Vit D3 level 135nmol/L 50-174

Serum free T3 level

6.6 pmol/L 3.1-6.8

Serum free T4 level

1.3pmol/L 10.8-25.5

Serum TSH level

0.12 mu/L 0.27-4.2

Serum Vitamin B12

1952 ng/L 180-999

Serum folate

20.0ug/L 3.89-26.8

HbA1c level-IFCC standardised

39.0 mmol/molly 20-41

Serum C Reactive Protein Level

11mg/L 0-5

Serum Albumin

40g/L 35-50

Serum bilirubin level

14umol/L 0-21

Serum alkaline phosphatase

126iu/L 30-130

Serum ALT level

41 u/L 0-40

Serum sodium

140mmol/L 133-146

Serum potassium

4.2mmol/L 3.5-5,3

Serum urea level

5.2mmol/L 2.5-7.8

Serum creatinine

72umol/L 44-80

GFR calculated abbreviated MDRD

76mL/min 90-120

Serum cortisol

156 nmol/L

Down from 579 nmol/L May 2022

Total white cell count

9.7 10*9/L 4-11

Haemoglobin estimation

156 g/dL 115-165

Platelet count

179 10*9/L 150-450

Red Blood cell count

5.12 10*12/L 3.9-5.8

Mean corpuscular volume (MCV)

94.3fL 78-97

Mean corpuscular Haemoglobin (MCG)

30.5pg 27-34

Mean corpuscular Hb.conc (MCHC)

324g/L 310-360

Red Blood Cell distribution width

16.3% 11.5-15

Haematocrit

0.483L/L 0.37-0.47

Mean Platelet volume

7.8 fL

Neutrophil count

7.0 10*9/L 1.5-8.0

Lymphocyte count

1.8 10*9/L 1.1-4.0

Monotype count

0.7 10*9/L 0.2-1.1

Eosinophil count

0.2 10*9/L 0.1-0.4

Basophil count

0.0 10*9/L 0-0.3

Serum Transferrin

2.65g/L 2-3.6

Serum Iron

14 umol/L 14-30

Transferrin saturation

21% 15-50

Serum Ferritin

318ug/L 30-400

Total Iron binding capacity

66umol/L 50-85

Sorry, quite a lot, but added normal as well as abnormal results FYI.

Thankyou to anyone who can help. I am currently on 40mcg T3 only.

Xxx

[SlowDragon Administrator]

why are you only taking just T3

Are you still only on 30mcg T3

Was test done as recommended

Recommended that all thyroid blood tests early morning, ideally just before 9am, only drink water between waking and test

T3 ….day before test split T3 as 2 or 3 smaller doses spread through the day, with last dose approximately 8-12 hours before test

low GFR suggests your hypo

ncbi.nlm.nih.gov/pmc/articl....

Thyroid hormones have pre-renal and intrinsic renal effects by which they increase the renal blood flow and the glomerular filtration rate (GFR). Hypothyroidism is associated with reduced GFR

[SlowDragon Administrator]

Serum Iron 14 umol/L 14-30

So you need to significantly increase iron rich foods in diet

[DandyButch in reply to SlowDragon]

Thank you for replying.I am on 40mcg liothyronine only daily.

I was on levothyroxine initially, but regardless of increases in dosage, I became progressively worse.

Since on T3 only, I do feel that I am finally going in the right direction, but, endocrinologist will not increase dosage due to TSH.

All protocols were followed for Blood tests.

[SlowDragon Administrator in reply to DandyButch]

So request experiment to add 25mcg levothyroxine alongside

Many people on T3 need SOME levothyroxine as well

Often members find they need BOTH Ft4 and Ft3 at least 50-60% through range

All protocols were followed for Blood tests.

So last 10mcg dose T3 approx 8-12 hours before test

[DandyButch in reply to SlowDragon]

Last 20mcg dose T3 16 hours before test.

[DandyButch]

I am scared about going back on levothyroxine, after the disturbing effects it caused.

[SlowDragon Administrator in reply to DandyButch]

Which brand of levothyroxine were you taking previously

many members who start off on T3 only experiment with slowly adding Levo back in after few months or years

Your T3 dose may be a bit high as it’s right at top of range after16 hours

Many, many people end up on mainly levo plus 20mcg T3 daily

Which brand of T3 are you taking

[DandyButch in reply to SlowDragon]

I have learnt that although a blood test may show near top of range, it doesn't show how much is reaching the cells, and actually working.

[DandyButch]

I was given various brands of levothyroxine. All were the same, even liquid levo. Even asking GP to specify a particular brand didn't work, because then pharmacy said they couldn't (or wouldn't) get it. So, no choice. This happened a few times. In the end, I stopped asking.Again, since being on liothyronine, I've had Roma, then a different one, and now, Mercury Pharma. TBH I haven't noticed any difference between brands. The only time I notice any difference is when I have an increase in dosage. Not necessarily instant, because I wonder about placebo affect, but after a few weeks, I see improvement in ability to do basic things, like going to bathroom etc. Bit graphic, but when on levo, couldn't walk to bathroom without holding wall.

[AKatieD]

Some people are said to need their T3 at the top of the range or slightly over. Maybe you should try a tiny bit more and see what it does?

T4 with T3 was no good for me either.

[DandyButch in reply to AKatieD]

Thankyou for your reply. I think I need more T3 but endocrinologist won't increase due to TSH!!!!!! Regardless of referring to research regarding dosing, and TSH levels, and optimal vitamins and minerals, she shut me down, saying she had studied and spent years at university etc, etc. So she was most qualified.I'm glad other people find T4 a no no.

I know I can self-medicate, but, trying to exhaust NHS first, then self source hopefully.

[AKatieD]

Keep up the good work, I get nothing from NHS.

Maybe you could argue that she may have studied lots but does not know how your body feels like you do.

[DandyButch in reply to AKatieD]

And......I'm older than her, and have more life experiences.