Help with results

[ShaneWarne]

Hello Everyone,

I am having heart palpitation and fast heart rate from quite sometime and loose stools.

Done several tests and ECGS all came back normal apart from b12 which was border line.

Last week did a private blood test (medichecks) for thyroid function along with other hormones to see my overall body function and results came back today. I just need a bit of help.

Full Blood Count:

HAEMOGLOBIN 125g/l (130-170)

HAEMATOCRIT 0.36 L/L (0.38 - 0.50)

RED CELL COUNT 3.83 (4.4 - 5.8)

Mean cell volume 95 (81 - 98)

Vitamins:

Folate 2.57 (>3-20)

B12 Active 28.6 pmol/l (37.5 - 188)

Vitamin D 15 nmol (50 - 175)

Iron Status:

Iron 20.64 (5.8 - 34.5)

Ferritin 107 (30 - 400)

Thyroid:

TSH 2.18 (0.27 - 4.2)

FREE T3 5.22 (3.1 - 6.8)

T4 19.5 (12 - 22)

Hormones:

FSH 6.41 (1.5 - 12.4)

LH 7.16 (1.7 - 8.6)

OESTRADIOL 105 (41 - 159)

TESTOSTERONE 12 (8.64 - 29)

FREE TESTOSTERONE - CALC 0.29 (0.2 - 0.62)

PROLACTIN 537 (86 - 324)

Adrenal Hormones:

DHEA SULPHATE 10.3 (4.34 - 12.2)

CORTISOL 571 (166-507)

Can someone please explain what these results indicate. Cortisol and Prolactin is very high and I did this test early in the morning and I was in a bit of stress at the time of the test.

[SeasideSusie Remembering]

ShaneWarne

I'm sure that you can see that you have some out of range results. You need to discuss these with your GP:

You're possibly looking at anaemia with these:

HAEMOGLOBIN 125g/l (130-170)

HAEMATOCRIT 0.36 L/L (0.38 - 0.50)

RED CELL COUNT 3.83 (4.4 - 5.8)

and with these:

Folate 2.57 (>3-20) - folate deficiency

B12 Active 28.6 pmol/l (37.5 - 188) - possible B12 deficiency as Active B12 below 70 suggests testing for B12 deficiency

viapath.co.uk/our-tests/act...

Vitamin D 15 nmol (50 - 175) - Vit D Deficiency - NICE Clinical Knowledge Summalry which your GP should follow and give you loading doses of D3:

cks.nice.org.uk/vitamin-d-d...

(click on Management > Scenario:Management)

I can't comment on hormones/adrenal test results.

[ShaneWarne in reply to SeasideSusie]

Thank you so much.

[SlowDragon Administrator]

your vitamin levels are EXTREMELY low

See GP for full testing for Pernicious Anaemia before starting on B12 injections and folic acid supplements, plus LOADING dose vitamin D

Insist on coeliac blood test and perhaps referral to gastroenterologist

[ShaneWarne in reply to SlowDragon]

Thank you for your reply. Intrinsic factor antibody test came back Negative.

Coeliac test also came back normal. Just saw my previous b12 results one on 2014 and one on 2017 both are border line low but my gp never told me about this.

GP just prescribed some B12 injections and I am going to have it this Thursday.

[SlowDragon Administrator in reply to ShaneWarne]

You clearly have some sort of gut issues going on

Referral to gastroenterologist would be good idea

gastris, h pylori, other gut infections

Getting all vitamins optimal is first step

Presumably your GP has also prescribed Folic acid

Folic acid supplements should not be started until 48 hours after first B12 injections

Your B12 is extremely low you likely need loading dose injections - several injections close together over next few weeks - ask advice on PAS healthunlocked

Vitamin D - GP should prescribe LOADING dose of vitamin D. That's 300,000iu over next 6-8 weeks

Bloods should be retested after 2-3 weeks to check calcium and parathyroid levels when on high dose vitamin D

Local CCG guidelines

clinox.info/clinical-suppor...

GP will only prescribe to bring vitamin D up to 50nmol. Aiming to improve by self supplementing vitamin D to at least 80nmol and around 100nmol may be better .







Once you Improve level, very likely you will need on going maintenance dose to keep it there.




Retesting twice yearly via vitamindtest.org.uk




Vitamin D mouth spray by Better You is good as avoids poor gut function.




It's trial and error what dose each person needs.

Suggest you retest thyroid including TPO and TG thyroid antibodies in 2-3 months. You may find cause of these low vitamins is Thyroid related. You need thyroid antibodies tested for autoimmune thyroid disease

For full Thyroid evaluation you need TSH, FT4 and FT3 plus both TPO and TG thyroid antibodies tested. Also important to test vitamin D, folate, ferritin and B12

Recommended on here that all thyroid blood tests should ideally be done as early as possible in morning and fasting. This gives highest TSH, lowest FT4 and most consistent results. (Patient to patient tip, best not mentioned to GP or phlebotomist)