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Two or three years of ADT?
My two-year-course if Lupron and abiraterone will be done in March 2025. My MO is saying 2 years is sufficient but I see some people suggesting 3 years. My situation. Dx in Feb 2023, PSA of 27. Gleason 4+3, BRACA2+, PSMA Pet showed three lymph nodes in pelvic area. 73 years old. Also diabetic and
My two-year-course if Lupron and abiraterone will be done in March 2025. My MO is saying 2 years is sufficient but I see some people suggesting 3 years. My situation. Dx in Feb 2023, PSA of 27. Gleason 4+3, BRACA2+, PSMA Pet showed three lymph nodes in pelvic area. 73 years old. Also diabetic and
BobC1234
in
Advanced Prostate Cancer
20 days ago
HRT and thyroid medication
Is it safe to take HRT with thyroid medication? Does taking the two together increase your risk of cancer ? thanks in advance.
Is it safe to take HRT with thyroid medication? Does taking the two together increase your risk of cancer ? thanks in advance.
Puddingym
in
Thyroid UK
20 days ago
Endo/ibs/perimeno/which one!?
Hi all. Very new here. I guess I’m just looking to see if anyone has any similar issues, a bit of reassurance and advise me on what the heck I’m meant to be doing! Went on the contraceptive pill at 17 as I got the most horrendous pain that would make me pass out nausea etc and they were very heavy.
Hi all. Very new here. I guess I’m just looking to see if anyone has any similar issues, a bit of reassurance and advise me on what the heck I’m meant to be doing! Went on the contraceptive pill at 17 as I got the most horrendous pain that would make me pass out nausea etc and they were very heavy.
Kateos81
in
Endometriosis UK
20 days ago
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Undiagnosed Hypothyroidism
I've been experiencing hypothyroid symptoms for a couple of years now. My TSH has been steadily creeping up, but so far has remained in the "normal" range when checked in my local surgery, around 3.4. I had some private tests done and my TSH was shown as 4.4 (June) and 5.9 (August). My second test
I've been experiencing hypothyroid symptoms for a couple of years now. My TSH has been steadily creeping up, but so far has remained in the "normal" range when checked in my local surgery, around 3.4. I had some private tests done and my TSH was shown as 4.4 (June) and 5.9 (August). My second test
gelatin
in
Thyroid UK
20 days ago
RA and menopause
I have RA and trying to decide if HRT is the route to go..I am on many meds for the RA and not sure if HRT is safe. I have had RA for 35 years and currently I am 55 years old. I have not had a period in 5 months. My symptoms are heart palpitations, anxiety, brain fog, and, hot flashes. Will it get easier
I have RA and trying to decide if HRT is the route to go..I am on many meds for the RA and not sure if HRT is safe. I have had RA for 35 years and currently I am 55 years old. I have not had a period in 5 months. My symptoms are heart palpitations, anxiety, brain fog, and, hot flashes. Will it get easier
ragurl
in
NRAS
20 days ago
I am trying to decide if I should take HRT. I
I have RA and trying to decide if HRT is the route to go..I am on many meds for the RA and not sure if HRT is safe. I have had RA for 35 years and currently I am 55 years old. I have not had a period in 5 months. My symptoms are heart palpitations, anxiety, brain fog, and, hot flashes. Will it get
I have RA and trying to decide if HRT is the route to go..I am on many meds for the RA and not sure if HRT is safe. I have had RA for 35 years and currently I am 55 years old. I have not had a period in 5 months. My symptoms are heart palpitations, anxiety, brain fog, and, hot flashes. Will it get
ragurl
in
Menopause and Perimenopause Support
20 days ago
If PSA rises when one is on ADT does it always mean resistance or can it be only a particular met growing ?
I see some posts here mention that some people had a psa rise and then got some met radiated and psa went down again. So one is on hormone therapy and psa rises , it does not necessarily mean one is getting castrate resistant ? Just trying to educate myself 😊
I see some posts here mention that some people had a psa rise and then got some met radiated and psa went down again. So one is on hormone therapy and psa rises , it does not necessarily mean one is getting castrate resistant ? Just trying to educate myself 😊
Tinkudi
in
Advanced Prostate Cancer
21 days ago
Coil for endo
I am currently going through the peri-menopause. My GP has strongly advised to have a coil fitted to fix my irregular heavy menstruation. Once this has been rectified I can have HRT that i desperately need. As a 49year old with no children I didn't want the coil fitted as I have heard horror stories
I am currently going through the peri-menopause. My GP has strongly advised to have a coil fitted to fix my irregular heavy menstruation. Once this has been rectified I can have HRT that i desperately need. As a 49year old with no children I didn't want the coil fitted as I have heard horror stories
GlobalTraveller
in
Endometriosis UK
21 days ago
Up and down…
I’m on 87.5mcg levo. My last blood tests showed low ferritin (32), t4 19.1 (12-22) t3 3.9 (3.1-6.8), slightly over range testosterone (on hrt but not on any testosterone). I’m seeing a thyroid specialist for the first time at the end of the month and will ask about iron testing and low ferritin, and
I’m on 87.5mcg levo. My last blood tests showed low ferritin (32), t4 19.1 (12-22) t3 3.9 (3.1-6.8), slightly over range testosterone (on hrt but not on any testosterone). I’m seeing a thyroid specialist for the first time at the end of the month and will ask about iron testing and low ferritin, and
JoJoloveschocolate
in
Thyroid UK
21 days ago
Do I have biochemical recurrence, is this hopefully just the bump?
One year and three months ago a had HD Brachyboost with full pelvic radiation for 4+3, but with high .88 decipher. Initial PSA 4.8 I was on one year Orgovyx and Nubeqa and finished three months ago. My nadir on ADT was 0.006. Today was my first post-ADT PSA test. It’s .313 and I’m shocked. I know
One year and three months ago a had HD Brachyboost with full pelvic radiation for 4+3, but with high .88 decipher. Initial PSA 4.8 I was on one year Orgovyx and Nubeqa and finished three months ago. My nadir on ADT was 0.006. Today was my first post-ADT PSA test. It’s .313 and I’m shocked. I know
SongofFred
in
Advanced Prostate Cancer
22 days ago
thyroid trouble please help!
first time poster here, 37yo M. I have been feeling exhausted for a long time now and been struggling with constipation. We can’t find a reason for this but my GP did some bloods that showed a normal T4/T3 but a TSH of 3.7 which is the upper limit of the normal range. I have been begging to trial thyroid
first time poster here, 37yo M. I have been feeling exhausted for a long time now and been struggling with constipation. We can’t find a reason for this but my GP did some bloods that showed a normal T4/T3 but a TSH of 3.7 which is the upper limit of the normal range. I have been begging to trial thyroid
T4warrior
in
Thyroid UK
22 days ago
1st frozen embryo transfer failed. Now to try again.
Hey all,So we went for frozen embryo transfer on 28th Aug with 5bc that had defrosted perfectly and my body responded well to the HRT fet protocol. Day 9 home preg test was neg right up until bloods on day 12 which also came back neg. Feeling down, low and upset along with anger and frustration. Want
Hey all,So we went for frozen embryo transfer on 28th Aug with 5bc that had defrosted perfectly and my body responded well to the HRT fet protocol. Day 9 home preg test was neg right up until bloods on day 12 which also came back neg. Feeling down, low and upset along with anger and frustration. Want
Lollypop1993
in
Fertility Network UK
22 days ago
Progesterone in HRT FET
Hello everyone, I just had a question about progesterone. So I did an IVF FET(HRT) on 16th Aug and was asked to test my progesterone during the TWW. On 22nd August my progesterone was 40.26 ng/mL I later went on to get a BFP and bhcg (24,000 now) has been rising as it should. Now I'm at 6w1d and tested
Hello everyone, I just had a question about progesterone. So I did an IVF FET(HRT) on 16th Aug and was asked to test my progesterone during the TWW. On 22nd August my progesterone was 40.26 ng/mL I later went on to get a BFP and bhcg (24,000 now) has been rising as it should. Now I'm at 6w1d and tested
Anon1206
in
Fertility Network UK - Pregnancy Support
22 days ago
Red light/ near infrared light therapy
I have been treating my foot and legs with red light/ near infrared light with the Leanne Venier Red juvenator biophotonic led light matrix #3 formula lights over the past 3 months. My treatment was for multiple fractures of my foot bones and ligament and tendon sprains. Over the course of a month
I have been treating my foot and legs with red light/ near infrared light with the Leanne Venier Red juvenator biophotonic led light matrix #3 formula lights over the past 3 months. My treatment was for multiple fractures of my foot bones and ligament and tendon sprains. Over the course of a month
maxkat22
in
Restless Legs Syndrome
8 months ago
Is muscle gain possible?
I've been on ADT for coming on two years and have suffered massive upper body mass and strength. Will machine or hand weight, band or body weight exercise bring it back or only stop it from getting worse? What are any rules to observe, how to start and when to increase weight?
I've been on ADT for coming on two years and have suffered massive upper body mass and strength. Will machine or hand weight, band or body weight exercise bring it back or only stop it from getting worse? What are any rules to observe, how to start and when to increase weight?
Wgly
in
Advanced Prostate Cancer
23 days ago
Kindly suggest the most appropriate next steps and questions for MO!
hi all! My dad was diagnosed in Feb2024 with metastatic prostate cancer, Gleason 8 and PSA 24. He is majorly asymptomatic. His PSA dropped to 0.16 and now has risen to 1.6 over a period of 2.5 months. He has been on hormone therapy and taking abireterone and prednisone daily. He got orchidectomy done
hi all! My dad was diagnosed in Feb2024 with metastatic prostate cancer, Gleason 8 and PSA 24. He is majorly asymptomatic. His PSA dropped to 0.16 and now has risen to 1.6 over a period of 2.5 months. He has been on hormone therapy and taking abireterone and prednisone daily. He got orchidectomy done
Justgettingitright
in
Advanced Prostate Cancer
23 days ago
Help with Female Hormone Test Interpretation
I did a Randox Female Hormone Test as NHS Endo refused to check Progesterone and Testosterone, and they don't believe in HRT. Until August 2022 I had been on HRT, Kliofem 2mg/ I mg , for more than 20 years. I was taken off it by my G.P. because of my age. I believe I have Pituitary Failure/ Central
I did a Randox Female Hormone Test as NHS Endo refused to check Progesterone and Testosterone, and they don't believe in HRT. Until August 2022 I had been on HRT, Kliofem 2mg/ I mg , for more than 20 years. I was taken off it by my G.P. because of my age. I believe I have Pituitary Failure/ Central
Wua13262348
in
Thyroid UK
23 days ago
second generation anti-androgens associated with cognitive and functional toxic effects
This study of 12 randomized clinical trials comprising 13 524 participants observed an increased risk of cognitive toxic effects, fatigue, and falls among individuals treated with second-generation AAs (abiraterone, apalutamide, darolutamide, or enzalutamide). A Systematic Review and Meta-analysis
This study of 12 randomized clinical trials comprising 13 524 participants observed an increased risk of cognitive toxic effects, fatigue, and falls among individuals treated with second-generation AAs (abiraterone, apalutamide, darolutamide, or enzalutamide). A Systematic Review and Meta-analysis
Graham49
in
Advanced Prostate Cancer
23 days ago
low iron and ursodiol
i’ve been on Urso for about two years now with good results and bringing my numbers back to the normal range. In the last year, I’ve been dealing with significant anxiety and I’ve not had this before. I am postmenopausal and have also been trying hormone replacement therapy in the form of patches and
i’ve been on Urso for about two years now with good results and bringing my numbers back to the normal range. In the last year, I’ve been dealing with significant anxiety and I’ve not had this before. I am postmenopausal and have also been trying hormone replacement therapy in the form of patches and
g00dandplenty
in
PBCers Organization
24 days ago
Help Hot Flush Nightmare
Is anyone else having trouble being prescribed Premarin, I have been denied my repeat prescription on grounds of ethics .I have been taking this HRT for 30 years plus ,I am now 74 and on the lowest dose.I have tried patches and other drugs but Premarin has been the best for me.Two weeks ago I was sent
Is anyone else having trouble being prescribed Premarin, I have been denied my repeat prescription on grounds of ethics .I have been taking this HRT for 30 years plus ,I am now 74 and on the lowest dose.I have tried patches and other drugs but Premarin has been the best for me.Two weeks ago I was sent
Peachrose17
in
Menopause and Perimenopause Support
24 days ago
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