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Xgeva
PSA down to .84, testosterone jumped a bit to 100 ct. I wrote before that because the undesirable side effects we, together with my Onco decided to stop Zytiga/Prednisone and just continue with Lupron injection every 4moths. On a previous post I said that I insisted on discontinuing Xgeva (afraid of
PSA down to .84, testosterone jumped a bit to 100 ct. I wrote before that because the undesirable side effects we, together with my Onco decided to stop Zytiga/Prednisone and just continue with Lupron injection every 4moths. On a previous post I said that I insisted on discontinuing Xgeva (afraid of
Blueribbon63
in
Advanced Prostate Cancer
1 year ago
Addition of Metastasis-Directed Therapy to Intermittent Hormone Therapy for Oligometastatic PC. The EXTEND Phase 2 Randomized Clinical Trial
MDT and intermittent ADT offer a progression free survival advantage when compared with intermittent ADT alone. "MDT facilitated a longer time with eugonadal testosterone as part of an intermittent hormone therapy strategy." "Time to new lesion failure was longer for patients randomized to combined
MDT and intermittent ADT offer a progression free survival advantage when compared with intermittent ADT alone. "MDT facilitated a longer time with eugonadal testosterone as part of an intermittent hormone therapy strategy." "Time to new lesion failure was longer for patients randomized to combined
tango65
in
Advanced Prostate Cancer
1 year ago
Zoladex implant problem ?
Fellow travellers I reach out for your help experience and knowledge of having any problems following the Zoladex 12 week implant administration I had 6 monthly Zoladex and then decidesd to try the 12 week version. I had it 8 days ago and for the first time it bled and required 5 mins pressure to stop
Fellow travellers I reach out for your help experience and knowledge of having any problems following the Zoladex 12 week implant administration I had 6 monthly Zoladex and then decidesd to try the 12 week version. I had it 8 days ago and for the first time it bled and required 5 mins pressure to stop
SimMartin
in
Advanced Prostate Cancer
1 year ago
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Hopefully On The Right Course
I have dealt with hypothyroidism and surgical menopause for several years. I did really well on oral estrogen and later put on levothyroxine when diagnosed with hypothyroidism and continued to do well until I didn't. Long story short I have seen several conventional and functional medical doctors for
I have dealt with hypothyroidism and surgical menopause for several years. I did really well on oral estrogen and later put on levothyroxine when diagnosed with hypothyroidism and continued to do well until I didn't. Long story short I have seen several conventional and functional medical doctors for
HeartWoman
in
Thyroid UK
1 year ago
Bipolar Androgen Therapy Followed by Androgen Receptor Inhibition as Sequential Therapy for Prostate Cancer
Here's a treat - a review of BAT (Bipolar Androgen Therapy), actually written by Dr. Sam Denmeade [1]. In his intro, he makes a point of stressing that androgen receptor axis therapies are "highly effective [i]
palliative
[/i] therapy, but they are
not curative
." A few years ago it was
Here's a treat - a review of BAT (Bipolar Androgen Therapy), actually written by Dr. Sam Denmeade [1]. In his intro, he makes a point of stressing that androgen receptor axis therapies are "highly effective [i]
palliative
[/i] therapy, but they are
not curative
." A few years ago it was
pjoshea13
in
Fight Prostate Cancer
1 year ago
Has anyone used testosterone gel (topical testosterone) to help improve egg quality?but had uncomfortable side effect?
I've been on the gel for a while now, on and off. I'm writing today to see if anyone has experienced acne on your labia or lumps inside the skin of your labia. (This is why I've been using on and off because once I stop, they go away) I have gone down the google rabbit hole, but cannot find anything.
I've been on the gel for a while now, on and off. I'm writing today to see if anyone has experienced acne on your labia or lumps inside the skin of your labia. (This is why I've been using on and off because once I stop, they go away) I have gone down the google rabbit hole, but cannot find anything.
Ca22
in
Fertility Network UK
1 year ago
Eligard failure?
Bear with me as I list the details behind my questions. I am currently receiving radiation treatment at UCLA under Dr Kishan on the Viewray (20 treatments vs 5 due to Prostox DNA test showing high risk to long term SE's from higher dose of radiation) and only have 2 treatments to go. Prior to coming
Bear with me as I list the details behind my questions. I am currently receiving radiation treatment at UCLA under Dr Kishan on the Viewray (20 treatments vs 5 due to Prostox DNA test showing high risk to long term SE's from higher dose of radiation) and only have 2 treatments to go. Prior to coming
LongevityAT
in
Advanced Prostate Cancer
1 year ago
ostarine
I have got locally advanced prostate cancer psa0.03 finished treatment 2016,but my testosterone has not recovered, been reading about ostarine anyone think it would be ok I am only 8st and without testosterone I'm struggling, asked for trt and be monitored but no I am a walking skeleton.
I have got locally advanced prostate cancer psa0.03 finished treatment 2016,but my testosterone has not recovered, been reading about ostarine anyone think it would be ok I am only 8st and without testosterone I'm struggling, asked for trt and be monitored but no I am a walking skeleton.
Radars
in
Advanced Prostate Cancer
1 year ago
My 25year old son's blood test results
Could these results suggest a Thyroid problem? Someone on the forum suggested investigating Pernicious Anaemia also. Jan'22 Ferritin 78ug/L (22-275) Folate 9.8 ug/L (3.0-20.0) Vit B12 472 ng/L (187 - 883) Sodium 142 (133-146) Potassium 4.2 (3.5-5.3) Chloride 103 (85 - 108) Urea 3.1 (2.5-7.8) Creatinine
Could these results suggest a Thyroid problem? Someone on the forum suggested investigating Pernicious Anaemia also. Jan'22 Ferritin 78ug/L (22-275) Folate 9.8 ug/L (3.0-20.0) Vit B12 472 ng/L (187 - 883) Sodium 142 (133-146) Potassium 4.2 (3.5-5.3) Chloride 103 (85 - 108) Urea 3.1 (2.5-7.8) Creatinine
Mindseye
in
Thyroid UK
1 year ago
my 25 year old son's blood test results
Could this be B12 deficiency? Jan'22 Ferritin 78ug/L (22-275) Folate 9.8 ug/L (3.0-20.0) Vit B12 472 ng/L (187 - 883) Sodium 142 (133-146) Potassium 4.2 (3.5-5.3) Chloride 103 (85 - 108) Urea 3.1 (2.5-7.8) Creatinine 82 (40-130) eGFR >59 (<60 - CKD stage 3.4 or 5) AST 20 (0-45) ALT 14 (0-55) Bilirubin
Could this be B12 deficiency? Jan'22 Ferritin 78ug/L (22-275) Folate 9.8 ug/L (3.0-20.0) Vit B12 472 ng/L (187 - 883) Sodium 142 (133-146) Potassium 4.2 (3.5-5.3) Chloride 103 (85 - 108) Urea 3.1 (2.5-7.8) Creatinine 82 (40-130) eGFR >59 (<60 - CKD stage 3.4 or 5) AST 20 (0-45) ALT 14 (0-55) Bilirubin
Mindseye
in
Pernicious Anaemia Society
1 year ago
Progesterone and oestradiol levels before transfer - can they be too high?
Hi Does anyone know what progesterone (nmol/L) and oestradiol (pmol/L) levels should be for a frozen transfer? I've just had an ERA and had these measured that day to help inform for the real transfer, whenever that might be! I know the progesterone in particular must not be too low. Mine seemed quite
Hi Does anyone know what progesterone (nmol/L) and oestradiol (pmol/L) levels should be for a frozen transfer? I've just had an ERA and had these measured that day to help inform for the real transfer, whenever that might be! I know the progesterone in particular must not be too low. Mine seemed quite
Skittles11
in
Fertility Network UK
1 year ago
FET prep first timer - tips for estradiol side effects
Hi everyone, Seeking as bit of wisdom on tips for managing the bloating and general malaise I'm feeling having recently started progynova for my first cycle as well as some general hints on staying sane! I'm on day 4 of FET prep with progynova tablets and it's not terrible but I feel sort of queasy
Hi everyone, Seeking as bit of wisdom on tips for managing the bloating and general malaise I'm feeling having recently started progynova for my first cycle as well as some general hints on staying sane! I'm on day 4 of FET prep with progynova tablets and it's not terrible but I feel sort of queasy
Minniemouse88
in
Fertility Network UK
1 year ago
Epigenetics - Heritability - Cadmium
Soon after diagnosis I joined a group headed by a man who viewed PCa as a modern disease with its origin in the womb. His bugbear was "Estrogen-like endocrine disrupting chemicals" (EEDC). I had come across the weird PCa risk factor of the second to fourth digit ratio, which seemed like voodoo science
Soon after diagnosis I joined a group headed by a man who viewed PCa as a modern disease with its origin in the womb. His bugbear was "Estrogen-like endocrine disrupting chemicals" (EEDC). I had come across the weird PCa risk factor of the second to fourth digit ratio, which seemed like voodoo science
pjoshea13
in
Fight Prostate Cancer
1 year ago
ADT Recommendations
I'm probably looking at starting salvage radiation soon with 4-6 months of ADT. The doc suggests starting with Casodex and then two sequential Lupron shots. Is there a better way to do ADT for that period? I'd like to get my testosterone back quickly at the end of the treatment period if possible.
I'm probably looking at starting salvage radiation soon with 4-6 months of ADT. The doc suggests starting with Casodex and then two sequential Lupron shots. Is there a better way to do ADT for that period? I'd like to get my testosterone back quickly at the end of the treatment period if possible.
ElRanchoDePoisonIvy
in
Advanced Prostate Cancer
1 year ago
Does a big drop in PSA a month after the start of hormone treatment possibly represent a higher chance of cure?
Hi all, I have been researching and I have been wondering if big drops in PSA right after hormone treatment should give you more hope at a cure or if this does not change the situation at all? Father PSA of 226 dropped to 3 one month after Firmagon shot, and then 0.3 a month after that, and then 0.13
Hi all, I have been researching and I have been wondering if big drops in PSA right after hormone treatment should give you more hope at a cure or if this does not change the situation at all? Father PSA of 226 dropped to 3 one month after Firmagon shot, and then 0.3 a month after that, and then 0.13
FormulaRob
in
Advanced Prostate Cancer
1 year ago
Female Testosterone Replacement Users
My endo has suggested I replace very low levels of testosterone with Androfeme, to complement my existing HRT package of Lenzetto and Utrogestan. After learning Androfeme costs £150.00 upward, and that my NHS GP already has female patients supplementing testosterone, I approached him to take on my prescription
My endo has suggested I replace very low levels of testosterone with Androfeme, to complement my existing HRT package of Lenzetto and Utrogestan. After learning Androfeme costs £150.00 upward, and that my NHS GP already has female patients supplementing testosterone, I approached him to take on my prescription
radd
in
Thyroid UK
1 year ago
some advice whilst on Estradiol!
Hi all, just wanted to come on here and share my thoughts. Due to have a FET W/C 6th March and the clinic have put me on estradiol. You’re meant to start this on your first day of period but Iv found that my period is like really light, very light brown which normally 3 days in I would be bleeding
Hi all, just wanted to come on here and share my thoughts. Due to have a FET W/C 6th March and the clinic have put me on estradiol. You’re meant to start this on your first day of period but Iv found that my period is like really light, very light brown which normally 3 days in I would be bleeding
KiteRunner123
in
Fertility Network UK
1 year ago
When do hot flashes end once ADT is suspended?
I was on ADT (Eligard) quarterly injections from January 2021 to November 2022 (two years). I am still experiencing the side effects of frequent hot flashes, low energy levels, weight gain, etc. I would just like to know when I might expect the hormones to have been "flushed-out" of my system and my
I was on ADT (Eligard) quarterly injections from January 2021 to November 2022 (two years). I am still experiencing the side effects of frequent hot flashes, low energy levels, weight gain, etc. I would just like to know when I might expect the hormones to have been "flushed-out" of my system and my
elwoodpdowd
in
Advanced Prostate Cancer
1 year ago
Hello, dear people!
I need your experience, your help. I m here for my father, i m here to find some answers and hope. My father found out in January 2022 (after his leg hurt about 2 months and nobody knew what he had) he s got PC with 120 PSA and some bone mets. When he had his CT, doctors found some modifications
I need your experience, your help. I m here for my father, i m here to find some answers and hope. My father found out in January 2022 (after his leg hurt about 2 months and nobody knew what he had) he s got PC with 120 PSA and some bone mets. When he had his CT, doctors found some modifications
tuta1960
in
Advanced Prostate Cancer
1 year ago
Determinants of PSA Response to Bipolar Androgen Therapy [BAT]
New study from Sartor et al below [1]. "Bipolar Androgen Therapy (BAT) is a novel therapy known to be effective in a subset of men with metastatic castrate resistant prostate cancer (mCRPC)." "Twenty five patients were non-responders and 16 were responders. Baseline characteristics between non-responders
New study from Sartor et al below [1]. "Bipolar Androgen Therapy (BAT) is a novel therapy known to be effective in a subset of men with metastatic castrate resistant prostate cancer (mCRPC)." "Twenty five patients were non-responders and 16 were responders. Baseline characteristics between non-responders
pjoshea13
in
Fight Prostate Cancer
1 year ago
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