Happy to share my latest progress report. Note that I am mHSPC, lymph nodes only to pelvis and abdomen. I have been on long-cycle modified BAT for 2.5 years now. 3 months of very high testosterone (400mg T-cypionate every 2 weeks), then one month of ADT using Orgovyx. My PSA has continued to decline on this regimen. It was down by 90% in January 2023 to 0.030. Now it has become undetectable <0.015. These were measured at towards the end of the ADT month of each cycle. So my next step will be to measure it during the high testosterone phases.
This provides a convincing example that, contrary to the "conventional thinking" that BAT is only appropriate for metastatic castrate resistant (mCRPC). That indeed it can be effective in controlling Hormone Sensitive PC. Perhaps even more so? I hope there will be a clinical trial for it soon. (Dr. Michael Schweizer? Denmeade? Anyone?)
However, my treatment also included an aggressive radiation treatment, which no doubt also contribute to the excellent response so far. That was SBRT to my oligometastatic nodes followed by molecular targeting radioligand treatments using the experimental monoclonal antibody ligand for Lu177: Lu-PSMA-J591 from GenesisCare in Perth Australia. Two infusions given one month after the SBRT.
Sending profound gratitude to all of my physicians and care teams for supporting me in my non SOC approaches. And to all of you, my friends and supporters on these forums. MateoBeach / Paul
BAT therapy/muscle pain.
First BAT cycle results: what next?
Stopping BAT 
Pausing BAT ?