Posts - Advanced Prostate Cancer | HealthUnlocked

Advanced Prostate Cancer

21,445 members • 26,866 posts

All posts for June 2024

AMG 509 trial

Hey Everyone, Has anyone here participated, or know anyone who has participated in the AMG 509 immunotherapy trial? My father has been presented with an...

Hey Everyone, Has anyone here participated, or know anyone who has participated...

user2626

•24 days ago

11 Replies

Tamsulosin

I’ve been on Tamsulosin since diagnosis. Now have unconnected (I think) issues with fluid build up in my lungs and consequential breathing issues. Now on...

I’ve been on Tamsulosin since diagnosis. Now have unconnected (I think) issues w...

FortyWinks

•24 days ago

9 Replies

Only ADT first or add second generation ADT too at start ?

Dad is going to start ADT shortly. He has bone mets One MO said to start with Zoladex and after two weeks to add xtandi ( starting 40 mg ) The other MO...

Dad is going to start ADT shortly. He has bone mets One MO said to start with...

Tinkudi

•24 days ago

40 Replies

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What are the better treatments for metastasis of the bone and pelvic lymph nodes?

Just found out the past few weeks from a biopsy and a PET/CT scan that the cancer was not contained in the prostate but metastasized to the pelvic lymph nodes...

Just found out the past few weeks from a biopsy and a PET/CT scan that the cance...

PARKER3237

•24 days ago

10 Replies

Do all get baseline testosterone before starting ADT

my MO had told to do a testosterone test two weeks after starting ADT but I was wondering do most do that or also get one before starting ?

my MO had told to do a testosterone test two weeks after starting ADT but I was ...

Tinkudi

•24 days ago

19 Replies

Antagonists - arrhythmia ?

this study seems to suggest that antagonists seem to have increased risk for arrhythmia but lower risk for MI...

this study seems to suggest that antagonists seem to have increased risk for arr...

Tinkudi

•24 days ago

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Kishan's 6 month Androgen Annihilation Therapy Study for metastatic PCa

https://x.com/prostatecell/status/1770206641813696808?s=46 https://bit.ly/43rr68x seems to be a promising tactic for oligometastatic PCa, that combines SBRT...

https://x.com/prostatecell/status/1770206641813696808?s=46 https://bit.ly/43rr6...

Xavier10

•24 days ago

2 Replies

LORIS AI predicts patient outcomes with immune checkpoint blockade therapy

Sort of important because immune checkpoint blockade therapy apparently has a lower success rate that bat bipolar androgen therapy. LORIS robustly predicts...

Sort of important because immune checkpoint blockade therapy apparently has a l...

cesanon

•24 days ago

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Cialis blues

Severe muscle cramps nighttime in my legs have recently been wrecking my sleep. After reading up, I discovered that pain in legs can be a side effect of...

Severe muscle cramps nighttime in my legs have recently been wrecking my sleep. ...

Purple-Bike

•24 days ago

2 Replies

QoL: Skanda Vale Hospice to be on BBC TV

The hospice that I attend is to be on nationwide television in August, to demonstrate their work in a half hour programme. I have agreed to do little segments...

The hospice that I attend is to be on nationwide television in August, to demons...

BrentW

•24 days ago

3 Replies

xgeva or zoledronic acid for bones ?

One MO has prescribed Xgeva and another MO has prescribed zoledronic acid to strengthen dad’s bones as he has to start ADT from Tomorrow. What are most...

One MO has prescribed Xgeva and another MO has prescribed zoledronic acid to str...

Tinkudi

•24 days ago

8 Replies

CTC circulating tumor cell count

I haven’t seen too much mention of CTC tests when PSA rises. Some rises at very low levels are not clearly correlated or confirmed by PET scans. So why...

I haven’t seen too much mention of CTC tests when PSA rises. Some rises at ver...

Steel67

•24 days ago

6 Replies

83 years old - Firmagon or Zoladex ? Conflicted which to choose.

Dad is 83 and has to start on ADT from Tomorrow. He has no known cardiac issues but we have a strong family history of cardiac disease. His dad and brother...

Dad is 83 and has to start on ADT from Tomorrow. He has no known cardiac issue...

Tinkudi

•24 days ago

1 Reply

Phase 1/2 ARV-766 clinical trial

“The purpose of this study is to assess the safety and tolerability (good and bad effects) and how prostate cancer responds to two different doses of the...

“The purpose of this study is to assess the safety and tolerability (good and ba...

Woodman33

•24 days ago

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PSA Still Going Up

I had RP on January 2023, started ADT in May 2023 and went through 38 sessions of radiation. In November 2023, my PSA went down to 0.005 ng/mL. My PSA went...

I had RP on January 2023, started ADT in May 2023 and went through 38 sessions o...

toyman79912

•25 days ago

9 Replies

FDA Greenlights Phase 2/3 Trial of KPG-121/Abiraterone in mCRPC

A clinical trial to evaluate the combination of a new drug called KPG-121 with abiraterone acetate (Zytiga) for treating metastatic castration-resistant...

A clinical trial to evaluate the combination of a new drug called KPG-121 with a...

God_Loves_Me

•25 days ago

2 Replies

Falling ALT - Pathway to Sarcopenia? - More Exercise Needed?

Two years in to my de novo high volume metastatic prostate cancer diagnosis, I am pleased to report excellent results so far with triplet therapy (Docetaxel...

Two years in to my de novo high volume metastatic prostate cancer diagnosis, I a...

JohnInTheMiddle

•25 days ago

32 Replies

Has Anyone Any Knowledge Concerning The Oregano Chief Compound, "Carvacrol" And Its Ability To Fight PCa?

There are tons of reports and articles on the internet that state that the chief Oregano herb compound Carvacrol outright "kills...

There are tons of reports and articles on the internet that state that ...

back2health

•25 days ago

16 Replies

Padcev drug under compassionate use? Anyone heard of this?

Hi. Asking for a friend whose husband has advanced PC and has run out of standard of care options. Oncologist just got approval for PadCev under compassionate...

Hi. Asking for a friend whose husband has advanced PC and has run out of standar...

StephH72

•25 days ago

3 Replies

JUN protein could slow prostate cancer growth, study finds

"The results, which have just been published in the top journal "Molecular Cancer", provide a new starting point for the development of therapies..... Our...

"The results, which have just been published in the top journal "Molecular Canc...

SimonHL

•25 days ago

1 Reply

Could This Alternative Regiment Be Decelerating My PSA?

Between Summer of 2021 and Summer of 2023--two solid years--my PSA went from 11.5 to 15.3, roughly two points per year. Having concern about my PSA,...

Between Summer of 2021 and Summer of 2023--two solid years--my PSA went fr...

back2health

•25 days ago

9 Replies

Casodex - stop or continue ?

Dad , 83 , got diagnosed last month with bone mets and psa 18. The urologist started him on Casodex 100 mg to take daily and then take a lupron shot after...

Dad , 83 , got diagnosed last month with bone mets and psa 18. The urologist s...

Tinkudi

•25 days ago

40 Replies

Some good news…

I’ve been trying to figure out some extreme lower back pain, and had another PSMA/PET scan today. I had visions of cancerous spread to my spine, and wanted to...

I’ve been trying to figure out some extreme lower back pain, and had another PSM...

Jpburns

•26 days ago

21 Replies

Nivolumab and Ipilimumab for Metastatic Prostate Cancer with an Immunogenic Signature: Phase 2 Trial

(UroToday.com) The 2024 American Society of Clinical Oncology (ASCO) annual meeting held in Chicago, IL between May 31 and June 4 was host to the Rapid Oral...

(UroToday.com) The 2024 American Society of Clinical Oncology (ASCO) annual meet...

God_Loves_Me

•26 days ago

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Best alternative PET for PSMA negative PCa

Asking for a friend. He was diagnosed 3 years ago with high risk high volume (Gleason 3+5) PCa. Treated with EBRT + LDRBT + ADT (18 months). His PSA was...

Asking for a friend. He was diagnosed 3 years ago with high risk high volume (Gl...

Vynbal

•26 days ago

12 Replies

Tibetan Therapy for prostate cancer

Hii , If anyone from India can tell his/her experience regarding Tibetan medicine for prostate cancer . There was one doctor Yeshi Dhodhen who is having good...

Hii , If anyone from India can tell his/her experience regarding Tibetan medici...

jeetu_g27

•26 days ago

5 Replies

Antihistamines for hot flushes

De Novo Gleason 9 plus 16 bone Mets diagnosed August 2022 at age 78. Commenced quarterly goserelin injections and PSA became unmeasurable. Side effects...

De Novo Gleason 9 plus 16 bone Mets diagnosed August 2022 at age 78. Commenced q...

Leigh2350

•26 days ago

43 Replies

Anyone above 80 years -on triple therapy ?

Anyone over 80 years who has taken triple therapy - first and second generation ADT as well as chemo ? Could you please share how your experience of it...

Anyone over 80 years who has taken triple therapy - first and second generation...

Tinkudi

•26 days ago

10 Replies

Osteoporosis and PCA

Just received results from BMD. All looks okay except for total left hip which went from 1.058 to 0.967. Is this of concern? What should I be asking my...

Just received results from BMD. All looks okay except for total left hip which w...

Lslal

•27 days ago

8 Replies

ADT failure

We saw my Dad's MO on 5/23. Over the course of 4 weeks my dad's PSA moved from 1.46 to 2.14, He said we need to be on Zytiga for three months before we can...

We saw my Dad's MO on 5/23. Over the course of 4 weeks my dad's PSA moved from 1...

lgutman

•27 days ago

23 Replies

Posts - Advanced Prostate Cancer | HealthUnlocked

Advanced Prostate Cancer

All posts for June 2024

AMG 509 trial

Tamsulosin

Only ADT first or add second generation ADT too at start ?

What are the better treatments for metastasis of the bone and pelvic lymph nodes?

Do all get baseline testosterone before starting ADT

Antagonists - arrhythmia ?

Kishan's 6 month Androgen Annihilation Therapy Study for metastatic PCa

LORIS AI predicts patient outcomes with immune checkpoint blockade therapy

Cialis blues

QoL: Skanda Vale Hospice to be on BBC TV

xgeva or zoledronic acid for bones ?

CTC circulating tumor cell count

83 years old - Firmagon or Zoladex ? Conflicted which to choose.

Phase 1/2 ARV-766 clinical trial

PSA Still Going Up

FDA Greenlights Phase 2/3 Trial of KPG-121/Abiraterone in mCRPC

Falling ALT - Pathway to Sarcopenia? - More Exercise Needed?

Has Anyone Any Knowledge Concerning The Oregano Chief Compound, "Carvacrol" And Its Ability To Fight PCa?

Padcev drug under compassionate use? Anyone heard of this?

JUN protein could slow prostate cancer growth, study finds

Could This Alternative Regiment Be Decelerating My PSA?

Casodex - stop or continue ?

Some good news…

Nivolumab and Ipilimumab for Metastatic Prostate Cancer with an Immunogenic Signature: Phase 2 Trial

Best alternative PET for PSMA negative PCa

Tibetan Therapy for prostate cancer

Antihistamines for hot flushes

Anyone above 80 years -on triple therapy ?

Osteoporosis and PCA

ADT failure

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