Posts - Advanced Prostate Cancer | HealthUnlocked

Advanced Prostate Cancer

21,438 members • 26,850 posts

All posts for June 2024

TLX591 (177Lu rosopatamab tetraxetan) demonstrated promising radiographic progression-free survival (rPFS) in mCRPC

"We are encouraged by this rPFS result, which compares favorably to small molecule radioligand therapy phase 1 and 2 studies at similar stages of development....

"We are encouraged by this rPFS result, which compares favorably to small molecu...

Maxone73

•21 days ago

1 Reply

EIS-12656, a first-in-class allosteric inhibitor of ALC1: will soon start a phase 1 trial

to PARP or not to PARP.... “EIS-12656 selectively targets tumors with no apparent effects on normal tissues.” ....“Our clinical study will also explore...

to PARP or not to PARP.... “EIS-12656 selectively targets tumors with no appare...

Maxone73

•21 days ago

2 Replies

Orgovyx Loading dose -3 tablets

Did all those on orgovyx do the loading dose of 3 tablets or some just start off as one daily. Any reactions to taking 3 together ?

Did all those on orgovyx do the loading dose of 3 tablets or some just start off...

Tinkudi

•21 days ago

19 Replies

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When do most do DEXA scan ?

Don’t doctors ask for a DEXA scan before they start ADT ? My doctor has written Prescription for ADT and denosumab without any baseline DEXA what if...

Don’t doctors ask for a DEXA scan before they start ADT ? My doctor has writte...

Tinkudi

•21 days ago

47 Replies

ADT and ankle swelling

I have stage 4 PC with mets to 2 vertebra, one rib and my pelvis. I have been on Lucrin injections 3 monthly, Abiraterone 1000mg daily plus Prednisone. The...

I have stage 4 PC with mets to 2 vertebra, one rib and my pelvis. I have been on...

Gimmishelter

•21 days ago

11 Replies

Starting relugolix - when to retest testosterone

So finally after much deliberation , decided to start dad on Relugolix. Since a few months a reputed indian Pharma company is making it too and it is quite...

So finally after much deliberation , decided to start dad on Relugolix. Since ...

Tinkudi

•21 days ago

34 Replies

Pluvicto

My dad had his 1st pluvicto injection beginning of May He had his PSA taken 3 weeks later. It went from 16 to 23. I’m hoping this isn’t an indicator that...

My dad had his 1st pluvicto injection beginning of May He had his PSA taken...

Jshaw916

•21 days ago

7 Replies

Updated: Father with aggressive cancer psa 2000, Hemoglobin 7

Not sure what’s happening. It’s not vomit. He keeps spitting blood with Saliva without his knowledge, no pain. Not a dental issue either. It looks like clot....

Not sure what’s happening. It’s not vomit. He keeps spitting blood with Saliva w...

Vishwa1890

•21 days ago

17 Replies

Will Estradiol 0.025 patch for hot flushes cause cancer to come out of hiding?

Hi My husband has been taking Effexor for hot flushes and it does not seem to be effective any longer . He increased the dose from 37.5 to 75 mg and that did...

Hi My husband has been taking Effexor for hot flushes and it does not seem to ...

positive-thinking

•21 days ago

32 Replies

Trying to decide my next step in my journey and was wondering what advice regarding treatment doctors?

I have seen the urologist and did a biopsy and PET/CT scan. Now that I have all the results, the urologist wants me to start treatments with his urology...

I have seen the urologist and did a biopsy and PET/CT scan. Now that I have all ...

PARKER3237

•21 days ago

27 Replies

Global radioligands trial phase 3 looks promising

using radioligands as first line in many different tumors seems to be effective...

using radioligands as first line in many different tumors seems to be effective....

Maxone73

•21 days ago

9 Replies

New delivery strategy!

Prodrugs and bacteria mediated delivery combined! Still not clinical but very promising for multiple cancers...

Prodrugs and bacteria mediated delivery combined! Still not clinical but very p...

Maxone73

•21 days ago

1 Reply

Has anyone taken Relugolix from start and no injections of ADT ?

Is relugolix reliable as compared to the adt injections ? Has anyone been only on that and not the injections ? How soon does it bring the testosterone...

Is relugolix reliable as compared to the adt injections ? Has anyone been only...

Tinkudi

•21 days ago

33 Replies

PSA rockets up to 344

Hello - I received quite shocking news during my visit to the Mayo Clinic last week. My PSA has jumped to 344 from a low of 3.6 last November, when I...

Hello - I received quite shocking news during my visit to the Mayo Clinic las...

Arcticfox44

•21 days ago

4 Replies

AMG 509 trial

Hey Everyone, Has anyone here participated, or know anyone who has participated in the AMG 509 immunotherapy trial? My father has been presented with an...

Hey Everyone, Has anyone here participated, or know anyone who has participated...

user2626

•21 days ago

11 Replies

Tamsulosin

I’ve been on Tamsulosin since diagnosis. Now have unconnected (I think) issues with fluid build up in my lungs and consequential breathing issues. Now on...

I’ve been on Tamsulosin since diagnosis. Now have unconnected (I think) issues w...

FortyWinks

•21 days ago

9 Replies

Only ADT first or add second generation ADT too at start ?

Dad is going to start ADT shortly. He has bone mets One MO said to start with Zoladex and after two weeks to add xtandi ( starting 40 mg ) The other MO...

Dad is going to start ADT shortly. He has bone mets One MO said to start with...

Tinkudi

•21 days ago

40 Replies

What are the better treatments for metastasis of the bone and pelvic lymph nodes?

Just found out the past few weeks from a biopsy and a PET/CT scan that the cancer was not contained in the prostate but metastasized to the pelvic lymph nodes...

Just found out the past few weeks from a biopsy and a PET/CT scan that the cance...

PARKER3237

•21 days ago

10 Replies

Do all get baseline testosterone before starting ADT

my MO had told to do a testosterone test two weeks after starting ADT but I was wondering do most do that or also get one before starting ?

my MO had told to do a testosterone test two weeks after starting ADT but I was ...

Tinkudi

•21 days ago

19 Replies

Antagonists - arrhythmia ?

this study seems to suggest that antagonists seem to have increased risk for arrhythmia but lower risk for MI...

this study seems to suggest that antagonists seem to have increased risk for arr...

Tinkudi

•22 days ago

Be the first to reply

Kishan's 6 month Androgen Annihilation Therapy Study for metastatic PCa

https://x.com/prostatecell/status/1770206641813696808?s=46 https://bit.ly/43rr68x seems to be a promising tactic for oligometastatic PCa, that combines SBRT...

https://x.com/prostatecell/status/1770206641813696808?s=46 https://bit.ly/43rr6...

Xavier10

•22 days ago

2 Replies

LORIS AI predicts patient outcomes with immune checkpoint blockade therapy

Sort of important because immune checkpoint blockade therapy apparently has a lower success rate that bat bipolar androgen therapy. LORIS robustly predicts...

Sort of important because immune checkpoint blockade therapy apparently has a l...

cesanon

•22 days ago

Be the first to reply

Cialis blues

Severe muscle cramps nighttime in my legs have recently been wrecking my sleep. After reading up, I discovered that pain in legs can be a side effect of...

Severe muscle cramps nighttime in my legs have recently been wrecking my sleep. ...

Purple-Bike

•22 days ago

2 Replies

QoL: Skanda Vale Hospice to be on BBC TV

The hospice that I attend is to be on nationwide television in August, to demonstrate their work in a half hour programme. I have agreed to do little segments...

The hospice that I attend is to be on nationwide television in August, to demons...

BrentW

•22 days ago

3 Replies

xgeva or zoledronic acid for bones ?

One MO has prescribed Xgeva and another MO has prescribed zoledronic acid to strengthen dad’s bones as he has to start ADT from Tomorrow. What are most...

One MO has prescribed Xgeva and another MO has prescribed zoledronic acid to str...

Tinkudi

•22 days ago

8 Replies

CTC circulating tumor cell count

I haven’t seen too much mention of CTC tests when PSA rises. Some rises at very low levels are not clearly correlated or confirmed by PET scans. So why...

I haven’t seen too much mention of CTC tests when PSA rises. Some rises at ver...

Steel67

•22 days ago

6 Replies

83 years old - Firmagon or Zoladex ? Conflicted which to choose.

Dad is 83 and has to start on ADT from Tomorrow. He has no known cardiac issues but we have a strong family history of cardiac disease. His dad and brother...

Dad is 83 and has to start on ADT from Tomorrow. He has no known cardiac issue...

Tinkudi

•22 days ago

1 Reply

Phase 1/2 ARV-766 clinical trial

“The purpose of this study is to assess the safety and tolerability (good and bad effects) and how prostate cancer responds to two different doses of the...

“The purpose of this study is to assess the safety and tolerability (good and ba...

Woodman33

•22 days ago

Be the first to reply

PSA Still Going Up

I had RP on January 2023, started ADT in May 2023 and went through 38 sessions of radiation. In November 2023, my PSA went down to 0.005 ng/mL. My PSA went...

I had RP on January 2023, started ADT in May 2023 and went through 38 sessions o...

toyman79912

•22 days ago

9 Replies

FDA Greenlights Phase 2/3 Trial of KPG-121/Abiraterone in mCRPC

A clinical trial to evaluate the combination of a new drug called KPG-121 with abiraterone acetate (Zytiga) for treating metastatic castration-resistant...

A clinical trial to evaluate the combination of a new drug called KPG-121 with a...

God_Loves_Me

•22 days ago

2 Replies

Posts - Advanced Prostate Cancer | HealthUnlocked

Advanced Prostate Cancer

All posts for June 2024

TLX591 (177Lu rosopatamab tetraxetan) demonstrated promising radiographic progression-free survival (rPFS) in mCRPC

EIS-12656, a first-in-class allosteric inhibitor of ALC1: will soon start a phase 1 trial

Orgovyx Loading dose -3 tablets

When do most do DEXA scan ?

ADT and ankle swelling

Starting relugolix - when to retest testosterone

Pluvicto

Updated: Father with aggressive cancer psa 2000, Hemoglobin 7

Will Estradiol 0.025 patch for hot flushes cause cancer to come out of hiding?

Trying to decide my next step in my journey and was wondering what advice regarding treatment doctors?

Global radioligands trial phase 3 looks promising

New delivery strategy!

Has anyone taken Relugolix from start and no injections of ADT ?

PSA rockets up to 344

AMG 509 trial

Tamsulosin

Only ADT first or add second generation ADT too at start ?

What are the better treatments for metastasis of the bone and pelvic lymph nodes?

Do all get baseline testosterone before starting ADT

Antagonists - arrhythmia ?

Kishan's 6 month Androgen Annihilation Therapy Study for metastatic PCa

LORIS AI predicts patient outcomes with immune checkpoint blockade therapy

Cialis blues

QoL: Skanda Vale Hospice to be on BBC TV

xgeva or zoledronic acid for bones ?

CTC circulating tumor cell count

83 years old - Firmagon or Zoladex ? Conflicted which to choose.

Phase 1/2 ARV-766 clinical trial

PSA Still Going Up

FDA Greenlights Phase 2/3 Trial of KPG-121/Abiraterone in mCRPC

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