Global radioligands trial phase 3 loo... - Advanced Prostate...

Advanced Prostate Cancer

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Global radioligands trial phase 3 looks promising

Maxone73 profile image
9 Replies

using radioligands as first line in many different tumors seems to be effective

sunnybrook.ca/research/medi...

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Maxone73 profile image
Maxone73
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GP24 profile image
GP24

It works for neuroendocrine tumors only.

TeleGuy profile image
TeleGuy in reply to GP24

I think the thought was that earlier may be better for radioligand therapy though TA reported recently on some research that 177Lu-PSMA treatments are as effective before as after chemo. I have Lutathera on my radar screen given that I have neuroendocrine differentiation. and my biopsy samples stain positive for somatostatin, which the 177Lu-Dotatate (Lutathera) is attracted to.

GP24 profile image
GP24 in reply to TeleGuy

I wanted to point out that the article Maxone cited does not refer to "many different tumors" but reports treatment of neuroendocrine tumors only.

I had 177Lu-PSMA therapy while being hormone sensitive. Therefore I am for early radioligand therapy.

TeleGuy profile image
TeleGuy in reply to GP24

Me too, though early castrate resistant but before chemo.

GP24 profile image
GP24 in reply to TeleGuy

I think TA refered to this study: novartis.com/news/media-rel...

DrawingSnowmen profile image
DrawingSnowmen in reply to GP24

“This trial is groundbreaking not only for patients with neuroendocrine cancers, but for all cancer patients as it has implications for the practice of cancer treatment broadly.”

GP24 profile image
GP24 in reply to DrawingSnowmen

The trial included patients with neuroendocrine tumors only. Therefore the results can only be applied to these tumors.

j-o-h-n profile image
j-o-h-n

Remember, getting married also looked promising.

Good Luck, Good Health and Good Humor.

j-o-h-n

Maxone73 profile image
Maxone73 in reply to j-o-h-n

Damn right!

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