Posts - Advanced Prostate Cancer | HealthUnlocked

Advanced Prostate Cancer

21,407 members • 26,792 posts

All posts for June 2024

Phase 1/2 ARV-766 clinical trial

“The purpose of this study is to assess the safety and tolerability (good and bad effects) and how prostate cancer responds to two different doses of the...

“The purpose of this study is to assess the safety and tolerability (good and ba...

Woodman33

•17 days ago

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PSA Still Going Up

I had RP on January 2023, started ADT in May 2023 and went through 38 sessions of radiation. In November 2023, my PSA went down to 0.005 ng/mL. My PSA went...

I had RP on January 2023, started ADT in May 2023 and went through 38 sessions o...

toyman79912

•18 days ago

9 Replies

FDA Greenlights Phase 2/3 Trial of KPG-121/Abiraterone in mCRPC

A clinical trial to evaluate the combination of a new drug called KPG-121 with abiraterone acetate (Zytiga) for treating metastatic castration-resistant...

A clinical trial to evaluate the combination of a new drug called KPG-121 with a...

God_Loves_Me

•18 days ago

2 Replies

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Falling ALT - Pathway to Sarcopenia? - More Exercise Needed?

Two years in to my de novo high volume metastatic prostate cancer diagnosis, I am pleased to report excellent results so far with triplet therapy (Docetaxel...

Two years in to my de novo high volume metastatic prostate cancer diagnosis, I a...

JohnInTheMiddle

•18 days ago

32 Replies

Has Anyone Any Knowledge Concerning The Oregano Chief Compound, "Carvacrol" And Its Ability To Fight PCa?

There are tons of reports and articles on the internet that state that the chief Oregano herb compound Carvacrol outright "kills...

There are tons of reports and articles on the internet that state that ...

back2health

•18 days ago

16 Replies

Padcev drug under compassionate use? Anyone heard of this?

Hi. Asking for a friend whose husband has advanced PC and has run out of standard of care options. Oncologist just got approval for PadCev under compassionate...

Hi. Asking for a friend whose husband has advanced PC and has run out of standar...

StephH72

•18 days ago

3 Replies

JUN protein could slow prostate cancer growth, study finds

"The results, which have just been published in the top journal "Molecular Cancer", provide a new starting point for the development of therapies..... Our...

"The results, which have just been published in the top journal "Molecular Canc...

SimonHL

•18 days ago

1 Reply

Could This Alternative Regiment Be Decelerating My PSA?

Between Summer of 2021 and Summer of 2023--two solid years--my PSA went from 11.5 to 15.3, roughly two points per year. Having concern about my PSA,...

Between Summer of 2021 and Summer of 2023--two solid years--my PSA went fr...

back2health

•18 days ago

9 Replies

Casodex - stop or continue ?

Dad , 83 , got diagnosed last month with bone mets and psa 18. The urologist started him on Casodex 100 mg to take daily and then take a lupron shot after...

Dad , 83 , got diagnosed last month with bone mets and psa 18. The urologist s...

Tinkudi

•18 days ago

40 Replies

Some good news…

I’ve been trying to figure out some extreme lower back pain, and had another PSMA/PET scan today. I had visions of cancerous spread to my spine, and wanted to...

I’ve been trying to figure out some extreme lower back pain, and had another PSM...

Jpburns

•19 days ago

21 Replies

Nivolumab and Ipilimumab for Metastatic Prostate Cancer with an Immunogenic Signature: Phase 2 Trial

(UroToday.com) The 2024 American Society of Clinical Oncology (ASCO) annual meeting held in Chicago, IL between May 31 and June 4 was host to the Rapid Oral...

(UroToday.com) The 2024 American Society of Clinical Oncology (ASCO) annual meet...

God_Loves_Me

•19 days ago

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Best alternative PET for PSMA negative PCa

Asking for a friend. He was diagnosed 3 years ago with high risk high volume (Gleason 3+5) PCa. Treated with EBRT + LDRBT + ADT (18 months). His PSA was...

Asking for a friend. He was diagnosed 3 years ago with high risk high volume (Gl...

Vynbal

•19 days ago

12 Replies

Tibetan Therapy for prostate cancer

Hii , If anyone from India can tell his/her experience regarding Tibetan medicine for prostate cancer . There was one doctor Yeshi Dhodhen who is having good...

Hii , If anyone from India can tell his/her experience regarding Tibetan medici...

jeetu_g27

•19 days ago

5 Replies

Antihistamines for hot flushes

De Novo Gleason 9 plus 16 bone Mets diagnosed August 2022 at age 78. Commenced quarterly goserelin injections and PSA became unmeasurable. Side effects...

De Novo Gleason 9 plus 16 bone Mets diagnosed August 2022 at age 78. Commenced q...

Leigh2350

•19 days ago

43 Replies

Anyone above 80 years -on triple therapy ?

Anyone over 80 years who has taken triple therapy - first and second generation ADT as well as chemo ? Could you please share how your experience of it...

Anyone over 80 years who has taken triple therapy - first and second generation...

Tinkudi

•20 days ago

10 Replies

Osteoporosis and PCA

Just received results from BMD. All looks okay except for total left hip which went from 1.058 to 0.967. Is this of concern? What should I be asking my...

Just received results from BMD. All looks okay except for total left hip which w...

Lslal

•20 days ago

8 Replies

ADT failure

We saw my Dad's MO on 5/23. Over the course of 4 weeks my dad's PSA moved from 1.46 to 2.14, He said we need to be on Zytiga for three months before we can...

We saw my Dad's MO on 5/23. Over the course of 4 weeks my dad's PSA moved from 1...

lgutman

•20 days ago

23 Replies

Did the Prostate Biopsy Pick Up What the MRI Missed? Or was it a Newer Developed Lesion

Back at the end of March (2024) I had an MRI which according to my urologist indicated 2 suspect areas he called "lesions." Two months later, at...

Back at the end of March (2024) I had an MRI which according to my urolog...

back2health

•20 days ago

22 Replies

Prediction of Resistance to 177Lu-PSMA Therapy by Assessment of Baseline Circulating Tumor DNA Biomarkers

https://jnm.snmjournals.org/content/64/11/1721 ”Taken together, despite these limitations, the role of ctDNA as a biomarker for response when using...

https://jnm.snmjournals.org/content/64/11/1721 ”Taken together, despite these l...

Shorehousejam

•20 days ago

1 Reply

What Is the Mechanism of Action for GcMAF?

I recently read an article about an enzyme called "nagalase" that's produced by cancer cells to inhibit the activity of macrophages and other...

I recently read an article about an enzyme called "nagalase" that's prod...

back2health

•20 days ago

2 Replies

could be of interest for those on BAT

Extreme responses to immune checkpoint blockade following bipolar androgen therapy and enzalutamide in patients with metastatic castration resistant prostate...

Extreme responses to immune checkpoint blockade following bipolar androgen thera...

Maxone73

•20 days ago

15 Replies

Question for Oncologist

Tall_Allen, if you are around, I would especially appreciate your thoughts…….my husband, Dave is still on Lupron/Zytiga/Pred for M1a pc. only in a few...

Tall_Allen, if you are around, I would especially appreciate your thoughts…….my ...

103532

•20 days ago

4 Replies

When to start treatment to ward off breast enlargement. Is it always necessary?

Gleason eight. Started orgovyx 1 month ago and imrt last week.

GeodesicDomeLife

•21 days ago

6 Replies

Fatigue and Pluvicto

Hi All. Last Tuesday, 28 May, I had my fourth infusion of Pluvicto. Did okay during isolation. Friday I went to an appointment and then did a little swimming....

Hi All. Last Tuesday, 28 May, I had my fourth infusion of Pluvicto. Did okay du...

MJCA

•21 days ago

28 Replies

Pre-approvals under Medicare

I have regular Medicare plus a supplement and Part D. I'm just starting to research this, but figured many of you have already dealt with this issue. Does...

I have regular Medicare plus a supplement and Part D. I'm just starting to resea...

dhccpa

•21 days ago

33 Replies

Have you done Cabazitaxel before Docetaxel?

If you did Cabazitaxel before docetaxel, then let me know what your experience was like. I know Cabazitaxel comes after Docetaxel. Recent publish...

If you did Cabazitaxel before docetaxel, then let me know what your experience...

God_Loves_Me

•21 days ago

8 Replies

Tall Allen

Everything Tall Allen has written on this site is exhaustively researched, clear, concise, and extremely helpful. What an asset he is.

Everything Tall Allen has written on this site is exhaustively researched, clear...

EchoII

•21 days ago

27 Replies

Hot Flashes

Centrum is advertising a number of products that reduce hot flashes in post menopausal women. Are any of these effective for those of us on ADT ?

Centrum is advertising a number of products that reduce hot flashes in post meno...

alperk

•21 days ago

1 Reply

How is the second generation ADT like xtandi , zytiga etc decided ?

What determines which second line ADT will be given to whom ? I see there is zytiga , xtandi , nubeqa and others. Is it just left to the MO to decide ?

What determines which second line ADT will be given to whom ? I see there is z...

Tinkudi

•21 days ago

15 Replies

Diarrhea caused by Zytiga or EBRT Radiation?

First, I want to thank everyone for responding to my question regarding fatigue due to radiation and/or Zytiga. My husband just finished 28 treatments of EBRT...

First, I want to thank everyone for responding to my question regarding fatigue ...

Usernameitis

•21 days ago

15 Replies

Posts - Advanced Prostate Cancer | HealthUnlocked

Advanced Prostate Cancer

All posts for June 2024

Phase 1/2 ARV-766 clinical trial

PSA Still Going Up

FDA Greenlights Phase 2/3 Trial of KPG-121/Abiraterone in mCRPC

Falling ALT - Pathway to Sarcopenia? - More Exercise Needed?

Has Anyone Any Knowledge Concerning The Oregano Chief Compound, "Carvacrol" And Its Ability To Fight PCa?

Padcev drug under compassionate use? Anyone heard of this?

JUN protein could slow prostate cancer growth, study finds

Could This Alternative Regiment Be Decelerating My PSA?

Casodex - stop or continue ?

Some good news…

Nivolumab and Ipilimumab for Metastatic Prostate Cancer with an Immunogenic Signature: Phase 2 Trial

Best alternative PET for PSMA negative PCa

Tibetan Therapy for prostate cancer

Antihistamines for hot flushes

Anyone above 80 years -on triple therapy ?

Osteoporosis and PCA

ADT failure

Did the Prostate Biopsy Pick Up What the MRI Missed? Or was it a Newer Developed Lesion

Prediction of Resistance to 177Lu-PSMA Therapy by Assessment of Baseline Circulating Tumor DNA Biomarkers

What Is the Mechanism of Action for GcMAF?

could be of interest for those on BAT

Question for Oncologist

When to start treatment to ward off breast enlargement. Is it always necessary?

Fatigue and Pluvicto

Pre-approvals under Medicare

Have you done Cabazitaxel before Docetaxel?

Tall Allen

Hot Flashes

How is the second generation ADT like xtandi , zytiga etc decided ?

Diarrhea caused by Zytiga or EBRT Radiation?

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