Have you done Cabazitaxel before Docetaxel?

[God_Loves_Me]

If you did Cabazitaxel before docetaxel, then let me know what your experience was like.

I know Cabazitaxel comes after Docetaxel.

Recent publish showed a significant response

Cabazitaxel/Abiraterone Yields PFS Improvement in mCRPC

Source :

cancernetwork.com/view/caba...

[Tall_Allen]

It makes no difference in survival:

ascopubs.org/doi/10.1200/JC...

[God_Loves_Me in reply to Tall_Allen]

Agree How about Quality of life ? Does Cabazitaxel improve Quality of life in compare to docetaxel ?

[Tall_Allen in reply to God_Loves_Me]

"peripheral neuropathy, peripheral edema, alopecia, and nail disorders were more frequent with D75...Cabazitaxel and docetaxel demonstrated different toxicity profiles, with overall less toxicity with C20."

Why do you ask? No one in his right mind would give you Jevtana first. You would lose your salvage for no benefit.

[God_Loves_Me in reply to Tall_Allen]

Thank you

[blabanieh in reply to Tall_Allen]

@Tall_Allen both oncologists (from different hospitals) have recommended Cabazitaxel as my dad's first chemo treatment instead of Docetaxel... why do you say no one would recommend Jevtana first?

[Tall_Allen in reply to blabanieh]

I just said why:"You would lose your salvage for no benefit." Jevtana is approved as salvage chemo when docetaxel fails.

[blabanieh in reply to Tall_Allen]

I’m seeing data online suggesting both are similarly effective as a first line chemo treatment ascopost.com/News/57923

[Tall_Allen in reply to blabanieh]

But you lose your opportunity for salvage chemo if you start with Jevtana.

[Yadifan]

For us it was an insurance issue. We were told insurance would cover docetaxel treatment before cabazitaxel.

[God_Loves_Me in reply to Yadifan]

Does your MO wanted to do cabazitaxel before docetaxel?

[Yadifan in reply to God_Loves_Me]

I had asked about cabazitaxel. His reply was insurance authorizes docetaxel first. His treatment suggestion was docetaxel first.

[j-o-h-n]

If I remember the alphabet correctly, then C should come before D.

Good Luck, Good Health and Good Humor.

j-o-h-n