Clinical Trial PT 112 ?

[Enilorac63]

I’m writing for my husband who is French (I’m English : we live in France )

He’s 65 and was diagnosed in March 2022 - already metastatic : PSA 36 (previous test 18months before was normal )

Mets in spine and pelvis also liver .

Enantone 3 monthly injections and Zytiga to start with. PSA went down from 56 to single digits but was short lived. Now castrate resistant.

BRCR 1 gene mutation so with Zytiga tried Niraparib in clinical trial but was in fact placebo so when PSA started climbing began Olaparib (Lynparza) - not effective so in November ‘23 began chemo Docetaxel ( PSA up to 500 ) with additional drug : Capivasertib (in Capitello trial)

After 4 rounds slight reduction in bone Mets but liver Mets on increase so came out of trial and he has now just begun a new clinical trial with PT 112 - I saw one post from someone on a similar trial and am wondering whether there is anyone else?

[TeleGuy]

I just posted my experience here:

healthunlocked.com/advanced...

Your husband might have better luck having a BRCA mutation, which I did not have.

[Maxone73]

hello, please look into a study called BRCAAWAY

[j-o-h-n]

There are a few posts in our H.U. History file regarding PT112.

Here's one of those posts that got many responses:

PT-112

1965l79Corvette profile image <----- user ID

1965l79Corvette•

3 years ago•49 Replies

Has anyone heard of a treatment trial PT-112?

Written by

1965l79Corvette profile image

1965l79Corvette

MaleUnited States

You may want to review other posts in the History file.

Good Luck, Good Health and Good Humor.

j-o-h-n