Blood test results: Hi all, can i have some help... - Thyroid UK

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Blood test results

cheekysaph profile image
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Hi all, can i have some help with blood test results? went to GP with symptoms of Hypothyroid, family history as both parents are diagnosed hypo. I was sent for full bloods incluing thyroid function 1/5/24 (bloods taken about 11am)

HbA1c 31 mmol n/a

Haemantinic

serum vit b12 322ng/l 189-883

serum folate 5.7ug/l 3.1-20.0

liver function

albumin 44 35-50

bilirubin level 10 <22

alkaline phosphatase 80 30-130

ALT level 14 <50

Urea and elcetrolytes

sodium 138 133-146

potasium 4.4 3.5-5.3

creatinine 57 49-90

eGFRcreat(CKD-EPI) 116 units n/a

Thyroid function

TSH level 3 0.4-5

free T4 11 9 to19

Full blood count

heamoglobin estimation 146 110-150

total white cell count 9 4to11

platelet count 309 150-400

RBC 4.81 3.8-4.8

Haematocrit 0.442 0.36-0.460

MCV 91.9 80-100

MCH 30.4 27-32

MCHC 330 320-360

Neutrophil count 6.4 2-7.5

Lymphocyte 1.6 1.5-4

monocyte count 0.5 0.2-1

eosinophil 0.4 0.02-0.5

basophil 0 <0.1

nucleated red cells 0 n/a

I requested GP appointment as i hadnt heard anything back about results, in appointment GP said all normal.... not convinceed as i still have sympotoms and my vitamin results were at lower end of normal.

I have since done a medichecks advanced thyroid test on 21/5/24 @7.30am

and here are the results, is it worth me going back to gp as the TSH level is wildy different!?

21/05/2024 medichecks

CRP HS <0.15

folate error

b12 -active 49.7 range 37.5-188

vitamin d 41.4 range 50-250

ferritin 41.3 range 30-169

TSH 7.49 0.27-4.2

free T3 4.7 (31.-6.8)

free thyroxine (t4) 16.1 (12-22)

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SlowDragon profile image
SlowDragonAdministrator

TSH 7.49 0.27-4.2

free T3 4.7 (31.-6.8)

free thyroxine (t4) 16.1 (12-22)

No thyroid antibodies test results?

About 90% of primary hypothyroidism is autoimmune thyroid disease, usually diagnosed by high TPO and/or high TG thyroid antibodies

Autoimmune thyroid disease with goitre is Hashimoto’s

Autoimmune thyroid disease without goitre is Ord’s thyroiditis.

Both are autoimmune and generally called Hashimoto’s.

Significant minority of Hashimoto’s patients only have high TG antibodies (thyroglobulin)

20% of autoimmune thyroid patients never have high thyroid antibodies and ultrasound scan of thyroid can get diagnosis

In U.K. medics hardly ever refer to autoimmune thyroid disease as Hashimoto’s (or Ord’s thyroiditis)

Send GP these results and request they retest thyroid including thyroid antibodies

Recommended that all thyroid blood tests early morning, ideally just before 9am, only drink water between waking and test

Book test for 9am latest

Technically you need 2 separate blood tests with TSH over 5 before starting a trial on levothyroxine

Starting levothyroxine - flow chart

gps.northcentrallondonccg.n...

meanwhile start working on extremely low vitamin levels

Low vitamin levels tend to lower TSH

Essential to regularly retest and maintain OPTIMAL vitamin levels by supplementing

Only add one vitamin supplement at a time. Then wait 10-14 days to assess before adding another

Start with vitamin D

cheekysaph profile image
cheekysaph in reply to SlowDragon

Yes sorry! forgot to add that part in

Thyroglobulin antibodies 42.4 (0-115)

Thyroid Peroxidase antibodies 9.9 (0-34)

SlowDragon profile image
SlowDragonAdministrator in reply to cheekysaph

20% of Hashimoto's patients never have raised antibodies

Orgainise an ultrasound scan via GP or privately

healthunlocked.com/thyroidu...

Paul Robson on atrophied thyroid - especially if no TPO antibodies

paulrobinsonthyroid.com/cou...

Gluten intolerance is often a hidden issue too.

Request coeliac blood test BEFORE considering trial on strictly gluten free diet

Unexplained vitamin deficiencies should get coeliac test via GP

SlowDragon profile image
SlowDragonAdministrator

vitamin d 41.4 range 50-250

Low vitamin D

GP should prescribe 1600iu everyday for 6 months

NHS Guidelines on dose vitamin D required

ouh.nhs.uk/osteoporosis/use...

GP will often only prescribe to bring vitamin D levels to 50nmol.

Some areas will prescribe to bring levels to 75nmol or even 80nmol

leedsformulary.nhs.uk/docs/...

GP should advise on self supplementing if over 50nmol, but under 75nmol (but they rarely do)

mm.wirral.nhs.uk/document_u...

But with thyroid issues, improving to around 80nmol or 100nmol by self supplementing may be better

pubmed.ncbi.nlm.nih.gov/218...

vitamindsociety.org/pdf/Vit...

Once you Improve level, very likely you will need on going maintenance dose to keep it there.

Test twice yearly when supplementing

Can test via NHS private testing service

vitamindtest.org.uk

Vitamin D mouth spray by Better You is very effective as it avoids poor gut function.

There’s a version made that also contains vitamin K2 Mk7.

One spray = 1000iu

amazon.co.uk/BetterYou-Dlux...

It’s trial and error what dose we need, with thyroid issues we frequently need higher dose than average

Try 3000iu daily and retest in 2-3 months

Vitamin D and thyroid disease

grassrootshealth.net/blog/t...

Vitamin D may prevent Autoimmune disease

newscientist.com/article/23...

Web links about taking important cofactors - magnesium and Vit K2-MK7

Magnesium best taken in the afternoon or evening, but must be four hours away from levothyroxine

betterbones.com/bone-nutrit...

medicalnewstoday.com/articl...

livescience.com/61866-magne...

sciencedaily.com/releases/2...

Recipe ideas

bbc.co.uk/food/articles/mag...

Interesting article by Dr Malcolm Kendrick on magnesium

drmalcolmkendrick.org/categ...

Vitamin K2 mk7

betterbones.com/bone-nutrit...

healthline.com/nutrition/vi...

SlowDragon profile image
SlowDragonAdministrator

serum vit b12 322ng/l 189-883

b12 -active 49.7 range 37.5-188

serum folate 5.7ug/l 3.1-20.0

Are you vegetarian or vegan?

B12 and folate both far too low

Low B12 symptoms

b12deficiency.info/signs-an...

methyl-life.com/blogs/defic...

NICE guidelines on B12 and testing

healthunlocked.com/redirect...

With serum B12 result below 500, (Or active B12 below 70) recommended to be taking a separate B12 supplement

A week later add a separate vitamin B Complex 

Then once your serum B12 is over 500 (or Active B12 level has reached 70), you may be able to reduce then stop the B12 and just carry on with the B Complex.

If Vegetarian or vegan likely to need ongoing separate B12 few times a week

Highly effective B12 drops

natureprovides.com/products...

Or

B12 sublingual lozenges

uk.iherb.com/pr/jarrow-form...

cytoplan.co.uk/shop-by-prod...

B12 range in U.K. is too wide

Interesting that in this research B12 below 400 is considered inadequate

healthunlocked.com/thyroidu...

Low folate

supplementing a good quality daily vitamin B complex, one with folate in (not folic acid)

This can help keep all B vitamins in balance and will help improve B12 levels too

Difference between folate and folic acid

healthline.com/nutrition/fo...

B vitamins best taken after breakfast

Igennus B complex popular option. Nice small tablets. Most people only find they need one per day. But a few people find it’s not high enough dose

Post discussing different B complex

healthunlocked.com/thyroidu...

Thorne Basic B recommended vitamin B complex that contains folate, but they are large capsules. (You can tip powder out if can’t swallow capsule) Thorne can be difficult to find at reasonable price, should be around £20-£25. iherb.com often have in stock. Or try ebay

IMPORTANT......If you are taking vitamin B complex, or any supplements containing biotin, remember to stop these 7 days before ALL BLOOD TESTS , as biotin can falsely affect test results

endo.confex.com/endo/2016en...

endocrinenews.endocrine.org...

In week before blood test, when you stop vitamin B complex, you might want to consider taking a separate folate supplement (eg Jarrow methyl folate 400mcg) and continue separate B12

Post discussing how biotin can affect test results

healthunlocked.com/thyroidu...

helvella.blogspot.com/p/hel...

SlowDragon profile image
SlowDragonAdministrator

ferritin 41.3 range 30-169

Look at increasing iron rich foods in your diet

Aiming to improve ferritin at least over 70

cks.nice.org.uk/topics/anae...

Serum ferritin level is the biochemical test, which most reliably correlates with relative total body iron stores. In all people, a serum ferritin level of less than 30 micrograms/L confirms the diagnosis of iron deficiency.

Never supplement iron without doing full iron panel test for anaemia first and retest 3-4 times a year if self supplementing.

It’s possible to have low ferritin but high iron

Test early morning, only water to drink between waking and test. Avoid high iron rich dinner night before test

Stop iron supplements 5-7 days before testing

Medichecks iron panel test

medichecks.com/products/iro...

Look at increasing iron rich foods in diet

Eating iron rich foods like liver or liver pate once a week plus other red meat, pumpkin seeds and dark chocolate, plus daily orange juice or other vitamin C rich drink can help improve iron absorption

List of iron rich foods

dailyiron.net

Links about iron and ferritin

irondisorders.org/too-littl...

davidg170.sg-host.com/wp-co...

Great in-depth article on low ferritin

oatext.com/iron-deficiency-...

drhedberg.com/ferritin-hypo...

This is interesting because I have noticed that many patients with Hashimoto’s disease and hypothyroidism, start to feel worse when their ferritin drops below 80 and usually there is hair loss when it drops below 50.

Posts discussing why important to do full iron panel test

healthunlocked.com/thyroidu...

Good iron but low ferritin

healthunlocked.com/thyroidu...

healthunlocked.com/thyroidu...

Chicken livers if iron is good, but ferritin low

healthunlocked.com/thyroidu...

Shellfish and Mussels are excellent source of iron

healthline.com/nutrition/he...

cheekysaph profile image
cheekysaph

Thanks for all the info, i will get reading!

what are your thought on the TSH going form 3 to 7.49 only 3 weeks apart?

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