Help with test results and next step please…on NDT

[DaisyJones1]

Hello all,

Would someone be able to offer any insight to my tests results here at all? Many thanks. I take 310mg of Erfa NDT. I have hypothyroidism (hashi) and am a 46 year old woman (so perimenopausal) and have two children. I exercise daily for at an hour. I have coeliac disease and am gluten free. The tests were done after 19hours of meds. I was day 15 of my cycle.

I take all my Erfa at one time (11am) on an empty stomach and wait an hour before any food/drink. I was trying to reduce my morning cortisol level so have been following this routine for 3months. Prior to this I was taking it in one go when I woke up about 5/6am . (I'm not keen to split my dose x3 as very busy and couldn't manage this protocol last time. I could manage this if there wasn't restriction on empty stomach beforehand and waiting an hour.)

I have been taking NDT for 10months. Generally I feel ok although weight gain is frustrating and upsetting, which occurred after a trial with T3. I then moved to NDT. I don't think I had such weight issues on T4 only.

I take a number of supplements: iron, magnesium, selenium, probiotic, zinc, ashwagandha (for cortisol). I am having occasional night time hypoglycaemic episodes (according to a CGM that I'm trying out), so not sure if that's related.

Any thoughts here and way forward at all?

Many thanks indeed,

Daisy

RESULTS

Saliva cortisol 6-10am: 20.10 Range <20.3

Saliva cortisol 12pm: 6.73 (high) range 1.6-5.6

Saliva cortisol 4pm: 4.14 range <6.94

Saliva cortisol 10pm: 1.51 range <7.56

Thyroid function test

TSH: <0.005 range 0.270-4/2

Free T3 6.8 range 3.1-6.8

Free thyroxine (FT4) (H) 26.2 range 12-22

Thryoglobuline antibodies 57.0 range 0-115

Thyroid peroxide antibodies (H) 51.6 range 0-34

Magnesium: 0.92 range 0.7-1.0

C reactive protein (h) 3.19 <3.0

25 OH Vit D 110 range 50-250

Liver function 41 range 35-50

Iron ferritin 70 range 30-150

Vit B12 591 (H) range 145-569

Luteinising hormone 5.2 (range luteal 1.0-11.4)

follicle stim. hormone 4.6 (range luteal 1.7-7.7)

17 Beta oestradiol 676 (range luteal 222-854)

sex hormone binding glob 122 (range 32.4-128)

Prolactin 307 (range 102-496)

testosterone 1.03

Free androgen index 0.8 (range 02.-71)

Free testosterone 0.007 (range 0.003-0.033)