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Increasing Dopamine receptor density?
Found randomly on the net : "There is a very powerful way to upregulate your dopamine receptor density, among other things, and it involves abstaining from sexual behaviours of any kind. Particularly self-pleasure and pornography watching. Fasting is another way. Any prolonged reduction of dopamine release
Found randomly on the net : "There is a very powerful way to upregulate your dopamine receptor density, among other things, and it involves abstaining from sexual behaviours of any kind. Particularly self-pleasure and pornography watching. Fasting is another way. Any prolonged reduction of dopamine release
Xenos
in
Cure Parkinson's
2 years ago
Parkinson's is not all in your head: Frozen Shoulder
I saw this picture the other day while researching frozen shoulder. It really hit me that PD is always described as problems being caused by dopamine cells dying in your brain and the subsequent lack of dopamine affecting your body. If you look at this picture and see the difference between the normal
I saw this picture the other day while researching frozen shoulder. It really hit me that PD is always described as problems being caused by dopamine cells dying in your brain and the subsequent lack of dopamine affecting your body. If you look at this picture and see the difference between the normal
Bolt_Upright
in
Cure Parkinson's
2 years ago
Parkinson's Disease - Hydrogen & Dopamine discussion with Dr. Joerg Birkmeyer and Mark Kent 11/26/2021
Parkinson's Disease - Hydrogen & Dopamine discussion with Dr. Joerg Birkmeyer and Mark Kent 11/26/2021 - https://youtu.be/py20sLqHeFs We discuss the relationship between hydrogen gas, L-Dopa, Dopamine and and how hydrogen producing bacteria can be the root cause of Parkinson's Disease and potential new
Parkinson's Disease - Hydrogen & Dopamine discussion with Dr. Joerg Birkmeyer and Mark Kent 11/26/2021 - https://youtu.be/py20sLqHeFs We discuss the relationship between hydrogen gas, L-Dopa, Dopamine and and how hydrogen producing bacteria can be the root cause of Parkinson's Disease and potential new
Bolt_Upright
in
Cure Parkinson's
2 years ago
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Clarification needed please Ellfindoe, Joolsg and others
I still struggle with the fact that RLS absolutely responds to Ropinirole, which is a dopamine-receptor agonist, but then we are told no to that, and are advised to take Gabapentin, which is an anticonvulsant medication. Stupid question but is that telling me that lack of dopamine causes the nerves
I still struggle with the fact that RLS absolutely responds to Ropinirole, which is a dopamine-receptor agonist, but then we are told no to that, and are advised to take Gabapentin, which is an anticonvulsant medication. Stupid question but is that telling me that lack of dopamine causes the nerves
67Waterman
in
Restless Legs Syndrome
2 years ago
The Ultimate Guide to Increasing Dopamine Naturally
Saw this link on FB. Seems like solid foundational advice: The Ultimate Guide to Increasing Dopamine Naturally https://www.vitamonk.com/blogs/health/natural-ways-to-boost-dopamine It's not geared towards PD. Lot's of reference links at the end.
Saw this link on FB. Seems like solid foundational advice: The Ultimate Guide to Increasing Dopamine Naturally https://www.vitamonk.com/blogs/health/natural-ways-to-boost-dopamine It's not geared towards PD. Lot's of reference links at the end.
Bolt_Upright
in
Cure Parkinson's
2 years ago
Anyone used Vitex (Agnus castus/chasteberry) and did it help or aggravate RLS?
Having heavy n prolonged periods so was researching solutions. Came across Vitex (to balance out hormones) but no idea if it's safe for RLS because when I googled Vitex RLS I read something about it affecting dopamine receptors? Has anyone used this for their periods or any other issue, or can advise
Having heavy n prolonged periods so was researching solutions. Came across Vitex (to balance out hormones) but no idea if it's safe for RLS because when I googled Vitex RLS I read something about it affecting dopamine receptors? Has anyone used this for their periods or any other issue, or can advise
ejaji
in
Restless Legs Syndrome
2 years ago
Supplementing Dopamine
If a person has symptoms of a dopamine deficit at any time throughout the day, is there any way to boost or supplement it without rx meds? I have adhd and rls. I don’t take stimulant meds because of age and hx of cardiac issues. I take gabapentin 600 mg at bedtime for rls. Occasionally I have to take
If a person has symptoms of a dopamine deficit at any time throughout the day, is there any way to boost or supplement it without rx meds? I have adhd and rls. I don’t take stimulant meds because of age and hx of cardiac issues. I take gabapentin 600 mg at bedtime for rls. Occasionally I have to take
JLBowman
in
Restless Legs Syndrome
2 years ago
Looking for the best supplement for pcos ?
Look no further , are you struggling on metformin ? , just taking Myo inositol ? Or maybe your not taking anything for your insulin resistance ? Let me introduce you to my lil friend, Inositol is a brilliant supplement. Inositol influences the action of insulin, a hormone essential for blood sugar control
Look no further , are you struggling on metformin ? , just taking Myo inositol ? Or maybe your not taking anything for your insulin resistance ? Let me introduce you to my lil friend, Inositol is a brilliant supplement. Inositol influences the action of insulin, a hormone essential for blood sugar control
Carly93
in
PCOS UK (Verity)
2 years ago
leukemia drug nilotinib could halt the progression of motor- and non-motor-related symptoms in Parkinson’s disease.
Specifically, they discovered that the 300-mg dose of nilotinib reversed these effects by inactivating a protein called DDR1 that affects the ability of the blood-brain barrier to function correctly. On the inhibition of DDR1 by nilotinib, the normal transportation of molecules in and out of the brain
Specifically, they discovered that the 300-mg dose of nilotinib reversed these effects by inactivating a protein called DDR1 that affects the ability of the blood-brain barrier to function correctly. On the inhibition of DDR1 by nilotinib, the normal transportation of molecules in and out of the brain
JustJeff
in
Cure Parkinson's
2 years ago
"A change in diet may reduce risk of lethal prostate cancer" Your thoughts on the study results below?
What do you all think of these findings, particularly regarding the foods listed? Some of them are known to be heathy, such as: fish, beans, nuts, pulses, spinach and beets! Also - What if you already have aggressive prostate cancer, then does eating the less lethal food, mentioned below, become less
What do you all think of these findings, particularly regarding the foods listed? Some of them are known to be heathy, such as: fish, beans, nuts, pulses, spinach and beets! Also - What if you already have aggressive prostate cancer, then does eating the less lethal food, mentioned below, become less
GeorgeGlass
in
Advanced Prostate Cancer
2 years ago
Has anyone in the US taken a long time to have their RLS diagnosed?
Has anyone in the US taken a long time to have their RLS diagnosed and then was put on a dopamine agonist which eventually resulted in augmentation? The reason I ask is there is a feature in the weekly Health section of the Washington Post called Medical Mysteries. It would be great to have one done
Has anyone in the US taken a long time to have their RLS diagnosed and then was put on a dopamine agonist which eventually resulted in augmentation? The reason I ask is there is a feature in the weekly Health section of the Washington Post called Medical Mysteries. It would be great to have one done
SueJohnson
in
Restless Legs Syndrome
2 years ago
My Dislike For Lyrica Grows by The Day
I also dislike mysteries. I like understanding. The other day a member posted that the first time he ever had RLS in his 30 years of life was shortly after he went cold turkey off of Pregabalin, which he was taking for other reasons. It absolutely has the tendency to do this. I will post case reports
I also dislike mysteries. I like understanding. The other day a member posted that the first time he ever had RLS in his 30 years of life was shortly after he went cold turkey off of Pregabalin, which he was taking for other reasons. It absolutely has the tendency to do this. I will post case reports
Hidden
in
Restless Legs Syndrome
2 years ago
Reference to the updated "Algorithm" for RLS treatment
Here is the reference and link to the updated "Algorithm" for RLS treatment. It's worth bringing the reference to your GP, neurologist and sleep specialist Silber, Michael H., Mark J. Buchfuhrer, Christopher J. Earley, Brian B. Koo, Mauro Manconi, John W. Winkelman, Christopher J. Earley, et al. “The
Here is the reference and link to the updated "Algorithm" for RLS treatment. It's worth bringing the reference to your GP, neurologist and sleep specialist Silber, Michael H., Mark J. Buchfuhrer, Christopher J. Earley, Brian B. Koo, Mauro Manconi, John W. Winkelman, Christopher J. Earley, et al. “The
GuillaumeL
in
Restless Legs Syndrome
2 years ago
11 minute BBC podcast - dopamine relevant
I stumbled on this 11 min World Service podcast - by accident really while I was walking - and was delighted to find it to be full of interesting information about the dopamine system. I recommend it if you can access it. https://www.bbc.co.uk/sounds/play/p09155ch Its called 'The Big Idea - The science
I stumbled on this 11 min World Service podcast - by accident really while I was walking - and was delighted to find it to be full of interesting information about the dopamine system. I recommend it if you can access it. https://www.bbc.co.uk/sounds/play/p09155ch Its called 'The Big Idea - The science
Smokeypurple
in
Cure Parkinson's
2 years ago
Overview of the Ataxias
🙂 This is lengthy, but it does have useful, interesting information. Overview of Adult Onset Cerebellar Ataxia Pravin Khemani, MD The ataxias are clinically heterogenous disorders caused by pathological processes affecting the cerebellum and cerebellar pathways resulting in impaired coordination. The
🙂 This is lengthy, but it does have useful, interesting information. Overview of Adult Onset Cerebellar Ataxia Pravin Khemani, MD The ataxias are clinically heterogenous disorders caused by pathological processes affecting the cerebellum and cerebellar pathways resulting in impaired coordination. The
wobblybee
in
Ataxia UK
2 years ago
Sudden return of speech.
My dad has a diagnosis of PSP and is currently in a care home. He has lost all mobility, is peg fed, finds it difficult to open his eyes and has not spoken since July. Over the past couple of weeks he has suddenly started to speak again. While this is lovely, I am aware it will not last and so will
My dad has a diagnosis of PSP and is currently in a care home. He has lost all mobility, is peg fed, finds it difficult to open his eyes and has not spoken since July. Over the past couple of weeks he has suddenly started to speak again. While this is lovely, I am aware it will not last and so will
Alib2408
in
PSP Association
2 years ago
FDA Approval Sought to Begin Phase 2 Trial of KM-819
FAScinate Therapeutics has submitted an investigational new drug (IND) application to the U.S. Food and Drug Administration (FDA) to initiate a Phase 2 clinical trial evaluating KM-819 as a potential therapy for Parkinson’s disease, the company announced in a press release. Parkinson’s disease is characterized
FAScinate Therapeutics has submitted an investigational new drug (IND) application to the U.S. Food and Drug Administration (FDA) to initiate a Phase 2 clinical trial evaluating KM-819 as a potential therapy for Parkinson’s disease, the company announced in a press release. Parkinson’s disease is characterized
Hidden
in
Cure Parkinson's
2 years ago
Augmentation
I guess I'm trying to determine if RLS augmentation is only experienced in those who have used dopamine agonists for a period of time? Or, do other classes of medications also cause augmentation to a degree? And last, how do we separate augmentation from the natural progression of untreated RLS? First
I guess I'm trying to determine if RLS augmentation is only experienced in those who have used dopamine agonists for a period of time? Or, do other classes of medications also cause augmentation to a degree? And last, how do we separate augmentation from the natural progression of untreated RLS? First
ziggypiggy
in
Restless Legs Syndrome
2 years ago
The Uric Acid Failure: Lessons Learned
RR = relative risk
Lesson one: Association ≠ Causation!
Mistaking association for causation is a major source of medical misunderstanding. It comes with real consequences, as we shall see. Observational studies can only find associations. Proving causation requires interventional studies
RR = relative risk
Lesson one: Association ≠ Causation!
Mistaking association for causation is a major source of medical misunderstanding. It comes with real consequences, as we shall see. Observational studies can only find associations. Proving causation requires interventional studies
park_bear
in
Cure Parkinson's
3 years ago
A STRANGE AND MIRACULOUS CURE!
Having RLS my ENTIRE life, I WAS taking practically every single OPOID and NEUROTROPIC drug everyone here is taking!! AND psychotropics as well...... a LONG list. Then, LONG story short...I was put on BUPRENORPHINE forSEVERE FIBROMYALGIA.......and the LIFE LONG RLS was COMPLETELY AND TOTALLY ABATED
Having RLS my ENTIRE life, I WAS taking practically every single OPOID and NEUROTROPIC drug everyone here is taking!! AND psychotropics as well...... a LONG list. Then, LONG story short...I was put on BUPRENORPHINE forSEVERE FIBROMYALGIA.......and the LIFE LONG RLS was COMPLETELY AND TOTALLY ABATED
Thursby
in
Restless Legs Syndrome
3 years ago
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