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Relief from home made electrolyte drink
Hi all, I've been suffering from RLS for about 7-8 years now. Have refused the dopamine options continually thrust at me by GPs (who prefer to believe their pharma rep than do any research - or read here!), and have done all the iron and magnesium tests, sleep apnea, etc, with no helpful conclusions.
Hi all, I've been suffering from RLS for about 7-8 years now. Have refused the dopamine options continually thrust at me by GPs (who prefer to believe their pharma rep than do any research - or read here!), and have done all the iron and magnesium tests, sleep apnea, etc, with no helpful conclusions.
Lovejoy100
in
Restless Legs Syndrome
2 years ago
4D pharma announces FDA clearance of IND application for Live Biotherapeutics MRx0005 and MRx0029 for the treatment of Parkinson’s disease
https://www.4dpharmaplc.com/en/newsroom/press-releases/fda-clearance-ind-mrx0005-and-mrx0029-parkinsons-disease About MRx0005 and MRx0029 MRx0005 and MRx0029 are oral single strain Live Biotherapeutic products in development for the treatment of neurodegenerative conditions such as Parkinson’s disease
https://www.4dpharmaplc.com/en/newsroom/press-releases/fda-clearance-ind-mrx0005-and-mrx0029-parkinsons-disease About MRx0005 and MRx0029 MRx0005 and MRx0029 are oral single strain Live Biotherapeutic products in development for the treatment of neurodegenerative conditions such as Parkinson’s disease
PDWarrior1900
in
Cure Parkinson's
2 years ago
PGE1, PGA1, Amodiaquine (AQ), Chloroquine (CQ), 5,6-Dihydroxyindole (DHI), Nurr1 and slowing progression
(This started as a post on PGE1 and PGA2, but then I found AQ, CQ, and DHI might do the same thing so I have changed the title) It has been 2 years since this was posted in HU: https://healthunlocked.com/cure-parkinsons/posts/143562876/2-compounds-show-ability-to-protect-neurons-raise-dopamine-levels
(This started as a post on PGE1 and PGA2, but then I found AQ, CQ, and DHI might do the same thing so I have changed the title) It has been 2 years since this was posted in HU: https://healthunlocked.com/cure-parkinsons/posts/143562876/2-compounds-show-ability-to-protect-neurons-raise-dopamine-levels
Bolt_Upright
in
Cure Parkinson's
2 years ago
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Instead of Mega Dosing B1, Try TTFD
added 6/25/23
I have stopped a 3rd time because I had return of symptoms (worsening of tremor) with none of my normal return of symptoms (anxiety, lose of sleep, constipation). I took a break and started back on on 1000mg of hcl. I was of 1100mg. Tremor has not gotten any better. Their seems to
added 6/25/23
I have stopped a 3rd time because I had return of symptoms (worsening of tremor) with none of my normal return of symptoms (anxiety, lose of sleep, constipation). I took a break and started back on on 1000mg of hcl. I was of 1100mg. Tremor has not gotten any better. Their seems to
Gcf51
in
Cure Parkinson's
2 years ago
Augmentation Study -Ecopipam
The latest edition of Nightwalkers, the US RLS foundation magazine, reports that Prof. Stefan Clemens of East Carolina University has applied for a patent to use Ecopipam to treat augmentation of RLS symptoms on dopaminergic drugs. He has licensed the product to Emalax Biosciences and trials will happen
The latest edition of Nightwalkers, the US RLS foundation magazine, reports that Prof. Stefan Clemens of East Carolina University has applied for a patent to use Ecopipam to treat augmentation of RLS symptoms on dopaminergic drugs. He has licensed the product to Emalax Biosciences and trials will happen
Joolsg
in
Restless Legs Syndrome
2 years ago
A supplement that should be an official antidepressant
Have any of you tried SAMe? It doesn’t help against anxiety, which is my main problem right now. But the fact that it is my main problem, and not depression, is squarely because of SAMe. I always feel bad that so many people could be helped by SAMe, and don’t know about it. It’s a natural supplement
Have any of you tried SAMe? It doesn’t help against anxiety, which is my main problem right now. But the fact that it is my main problem, and not depression, is squarely because of SAMe. I always feel bad that so many people could be helped by SAMe, and don’t know about it. It’s a natural supplement
Zyxx
in
Anxiety and Depression Support
2 years ago
CHAPTER 6.THE SEARCH FOR HOPE "OUTSIDE" THE BUBBLE: OTHER NEUROLOGISTS, OTHER MEDICINES, OTHER DISEASES...
Explanation: I would like to share this chapter with all of you. Because of a worsening in my mother's health, I don't know when I will be able to resume the English translation of my book on curing Parkinson's. I will be sharing some chapters in this extraordinary forum. I have to stop my investigation
Explanation: I would like to share this chapter with all of you. Because of a worsening in my mother's health, I don't know when I will be able to resume the English translation of my book on curing Parkinson's. I will be sharing some chapters in this extraordinary forum. I have to stop my investigation
parkinsonshereandnow
in
Cure Parkinson's
2 years ago
Making rls manageable, a continuing story
I have had quite bad rls for the last two years and over time, very little sleep. However I have tried to persevere without drugs, although my GP has prescribed low dose codeine (15mg) which helped at first but I now try not to take. My rls is currently much better. It hasn’t gone away but it’s sort
I have had quite bad rls for the last two years and over time, very little sleep. However I have tried to persevere without drugs, although my GP has prescribed low dose codeine (15mg) which helped at first but I now try not to take. My rls is currently much better. It hasn’t gone away but it’s sort
Bluebboat
in
Restless Legs Syndrome
2 years ago
Aspen Neuroscience announces $147.5M financing to fund trials of the company’s 1st iPSC-derived autologous dopamine neuron replacement
WOW! @McdevittDamien Aspen Neuroscience colleagues announces $147.5M (!!!) in Series B financing to help fund clinical trials of the company’s 1st iPSC-derived autologous dopamine neuron replacement for #Parkinsons https://twitter.com/ScienceofPD/status/1523790152941723649 https://aspenneuroscience.com
WOW! @McdevittDamien Aspen Neuroscience colleagues announces $147.5M (!!!) in Series B financing to help fund clinical trials of the company’s 1st iPSC-derived autologous dopamine neuron replacement for #Parkinsons https://twitter.com/ScienceofPD/status/1523790152941723649 https://aspenneuroscience.com
Hidden
in
Cure Parkinson's
2 years ago
Researchers identify a subtype of brain cells that die in Parkinson's patients
A new study spurs in identifying a new patho-physiology path to PD and it sheds to re-exam areas needed to consider in its diagnosis . " Prior research has shown that the disease arises when nerve cells in the substantia nigra (located in the midbrain) deteriorate for unknown reasons. As a result,
A new study spurs in identifying a new patho-physiology path to PD and it sheds to re-exam areas needed to consider in its diagnosis . " Prior research has shown that the disease arises when nerve cells in the substantia nigra (located in the midbrain) deteriorate for unknown reasons. As a result,
Abdiqani
in
Cure Parkinson's
2 years ago
Dopamine stress test
Hi I'm due to have a dopamine stress test on my heart in which I will be injected with dopamine to medically speed up my hr whilst I'm lying on the bed. I've also been told they could use atropine also. Has anyone else had this done and has anyone any advice. Thank you xx Michelle
Hi I'm due to have a dopamine stress test on my heart in which I will be injected with dopamine to medically speed up my hr whilst I'm lying on the bed. I've also been told they could use atropine also. Has anyone else had this done and has anyone any advice. Thank you xx Michelle
Michelle_c
in
British Heart Foundation
2 years ago
Who wakes up “on”?
Can you please indicate if when you wake up you need a dose of levodopa to be able to move, and who feels best first thing before a dose? I just found this picture. Ignore the schitzophrenia references, I just found it interesting how dopamine levels fluctuate during the day naturally in a normal person
Can you please indicate if when you wake up you need a dose of levodopa to be able to move, and who feels best first thing before a dose? I just found this picture. Ignore the schitzophrenia references, I just found it interesting how dopamine levels fluctuate during the day naturally in a normal person
LAJ12345
in
Cure Parkinson's
2 years ago
A great article about Mucuna by Michael okun
7 Tips for using mucuna pruriens in Parkinson's disease: A plant-based form of dopamine http://parkinsonsecrets.com/blog/2022/5/3/is-there-a-plant-based-natural-dopamine-for-parkinsons-5-things-you-need-to-know-about-mucuna
7 Tips for using mucuna pruriens in Parkinson's disease: A plant-based form of dopamine http://parkinsonsecrets.com/blog/2022/5/3/is-there-a-plant-based-natural-dopamine-for-parkinsons-5-things-you-need-to-know-about-mucuna
Farooqji
in
Cure Parkinson's
2 years ago
Timings of medications
I’m wondering if it’s a good idea to take medication n supplements together at the same time (in the morning) coz if I don’t, I forget to take later in the day. Or is it better to space them out? Which supplements can be take together with dopamine to increase on time? I am on sinemet 100/25 tds, selegiline
I’m wondering if it’s a good idea to take medication n supplements together at the same time (in the morning) coz if I don’t, I forget to take later in the day. Or is it better to space them out? Which supplements can be take together with dopamine to increase on time? I am on sinemet 100/25 tds, selegiline
Divii
in
Cure Parkinson's
2 years ago
Gut bacterial tyrosine decarboxylases restrict levels of levodopa in the treatment of Parkinson’s disease
https://www.nature.com/articles/s41467-019-08294-y “Several amino acid decarboxylases have been identified in bacteria. Tyrosine decarboxylase (TDC) genes (tdc) have especially been encoded in the genome of several bacterial species in the genera Lactobacillus and Enterococcus17,18. Though TDC is named
https://www.nature.com/articles/s41467-019-08294-y “Several amino acid decarboxylases have been identified in bacteria. Tyrosine decarboxylase (TDC) genes (tdc) have especially been encoded in the genome of several bacterial species in the genera Lactobacillus and Enterococcus17,18. Though TDC is named
LAJ12345
in
Cure Parkinson's
2 years ago
Medications not fully helping :(
Nowadays, even after taking dopamine, I don’t feel well- mostly towards end of the day but sometimes towards beginning. I supplement with dopamine agonists Small dose- ropinorole 0.125 mg; it helps a little. I am feeling weak on my right side constantly. Vitamin B1 hasn’t helped me fully. Any suggestions
Nowadays, even after taking dopamine, I don’t feel well- mostly towards end of the day but sometimes towards beginning. I supplement with dopamine agonists Small dose- ropinorole 0.125 mg; it helps a little. I am feeling weak on my right side constantly. Vitamin B1 hasn’t helped me fully. Any suggestions
Divii
in
Cure Parkinson's
2 years ago
Functional Recovery from Human Induced Pluripotent Stem Cell-Derived Dopamine Neuron Grafts is Dependent on Neurite Outgrowth
Summary Transplantation of human pluripotent stem cell-derived dopaminergic (DA) neurons is an emerging therapeutic strategy for Parkinson’s disease (PD). In this study, we demonstrate, for the first time, that that functional recovery after DA neuron transplant is critically dependent on graft-host
Summary Transplantation of human pluripotent stem cell-derived dopaminergic (DA) neurons is an emerging therapeutic strategy for Parkinson’s disease (PD). In this study, we demonstrate, for the first time, that that functional recovery after DA neuron transplant is critically dependent on graft-host
Farooqji
in
Cure Parkinson's
2 years ago
Stem Cell-Based Treatment for Parkinson's Disease -- Where do we stand?
Following_closely shared this video on another thread. https://youtu.be/h8aIHkJBe60 "Dr. Studer is the director of the Center for Stem Cell Biology at Memorial-Sloan Kettering Cancer Center in New York City. He is a developmental biologist and neuroscientist pioneering the generation of midbrain dopamine neurons
Following_closely shared this video on another thread. https://youtu.be/h8aIHkJBe60 "Dr. Studer is the director of the Center for Stem Cell Biology at Memorial-Sloan Kettering Cancer Center in New York City. He is a developmental biologist and neuroscientist pioneering the generation of midbrain dopamine neurons
Bolt_Upright
in
Cure Parkinson's
2 years ago
How A Banana Before Bed Can Help You Sleep Better
But did you know bananas can also help you sleep? It turns out; this beloved fruit is the perfect sleep aid. It provides several vitamins and minerals that can improve the quality of your sleep. Bananas reduce stress and anxiety, alleviate muscle cramps, and regulate your sleep-wake cycle with serotonin
But did you know bananas can also help you sleep? It turns out; this beloved fruit is the perfect sleep aid. It provides several vitamins and minerals that can improve the quality of your sleep. Bananas reduce stress and anxiety, alleviate muscle cramps, and regulate your sleep-wake cycle with serotonin
Thal
in
Cure Parkinson's
2 years ago
Sudden loss of ability to move?
Hello all, I haven't been posting much. But I'd appreciate your advice. On Friday, my husband was going about his day, had driven to the grocery pickup, got home, and then started to have small hallucinations (ants that weren't there) and vomited. He texted for me to come home from work, and in the
Hello all, I haven't been posting much. But I'd appreciate your advice. On Friday, my husband was going about his day, had driven to the grocery pickup, got home, and then started to have small hallucinations (ants that weren't there) and vomited. He texted for me to come home from work, and in the
LostinHeadSpace
in
PSP Association
2 years ago
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