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Zeolites?
Encountered this while doing a little reading. Started me wondering. Posted to see what other people might think or do with this one. Using Natural Zeolite as a Transporter of Dopamine https://neuro.psychiatryonline.org/doi/full/10.1176/appi.neuropsych.12010018#:~:text=One%20research%20study%20shows
Encountered this while doing a little reading. Started me wondering. Posted to see what other people might think or do with this one. Using Natural Zeolite as a Transporter of Dopamine https://neuro.psychiatryonline.org/doi/full/10.1176/appi.neuropsych.12010018#:~:text=One%20research%20study%20shows
MarionP
in
Cure Parkinson's
9 months ago
Neupro Patch Weaning
I’ve read most of the forum’s input regarding Neupro Patches and relayed the information to the physician. He has decided to optimize the Gabapentin dose and discontinue the patch. A bit of history…….. the patch was started 12/19/23…10 days ago. Prior to that, ropinirole was weaning off (dose on
I’ve read most of the forum’s input regarding Neupro Patches and relayed the information to the physician. He has decided to optimize the Gabapentin dose and discontinue the patch. A bit of history…….. the patch was started 12/19/23…10 days ago. Prior to that, ropinirole was weaning off (dose on
Busunsc713
in
Restless Legs Syndrome
9 months ago
Escape from Augmentation
I have continued to make progress on my path to getting my dopamine receptors back to somewhere near normal. I last used a DA patch in September. I am using buprenorphine patches and pregabalin as RLS blockers to assist in the process. There is some improvement (perhaps 60%) in my sleep regime and in
I have continued to make progress on my path to getting my dopamine receptors back to somewhere near normal. I last used a DA patch in September. I am using buprenorphine patches and pregabalin as RLS blockers to assist in the process. There is some improvement (perhaps 60%) in my sleep regime and in
davchar23
in
Restless Legs Syndrome
9 months ago
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Dr. Jonathan Sackner-Bernstein & Dopamine
https://www.prnewswire.com/news-releases/could-all-the-experts-be-wrong-about-parkinsons-301308244.html Our forum has been discussing this lately and I must say that I dismissed it initially before at long last going on to read his research/analysis with more attention. I was intrigued because
https://www.prnewswire.com/news-releases/could-all-the-experts-be-wrong-about-parkinsons-301308244.html Our forum has been discussing this lately and I must say that I dismissed it initially before at long last going on to read his research/analysis with more attention. I was intrigued because
pdpatient
in
Cure Parkinson's
9 months ago
The Strongest Neurotransmitter in the World is NOT Dopamine or Serotonin - Dr. Scott Sherr MD
This is very interesting. Explains interaction of glutamate, GABA, B6, magnesium anxiety, depression https://youtu.be/twNwe5WOOdI?si=dSIKRr3aPvgtuOyE
This is very interesting. Explains interaction of glutamate, GABA, B6, magnesium anxiety, depression https://youtu.be/twNwe5WOOdI?si=dSIKRr3aPvgtuOyE
LAJ12345
in
Cure Parkinson's
9 months ago
Drug fails in Phase II trial for treating Parkinson's Disease - Exenatide (Byetta, Bydureon)
Evidence suggest that microglia are relevant to Parkinson's disease pathogenesis, therefore the recent clinical trial warranted exploration of trying to attenuate pathogenic microglial function. They sought to test the safety and efficacy of NLY01—a brain penetrant, pegylated, longer-lasting version
Evidence suggest that microglia are relevant to Parkinson's disease pathogenesis, therefore the recent clinical trial warranted exploration of trying to attenuate pathogenic microglial function. They sought to test the safety and efficacy of NLY01—a brain penetrant, pegylated, longer-lasting version
Baron1
in
Cure Parkinson's
9 months ago
Will I always be on ADHD meds?
Hi All, I tried a day without adhd meds and I only realised how bad my ADHD is and am shocked how I had to always live like this. I have put on my glasses so now when I take them off I know how bad it is. I think there is an unfair stigma of choosing to be on adhd meds. Let me explain why I think it
Hi All, I tried a day without adhd meds and I only realised how bad my ADHD is and am shocked how I had to always live like this. I have put on my glasses so now when I take them off I know how bad it is. I think there is an unfair stigma of choosing to be on adhd meds. Let me explain why I think it
Salah_09
in
CHADD's Adult ADHD Support
9 months ago
Escape from DA Augmentation
Thanks to the support of several contributors to this forum and especially Joolsg, LotteM, and my patient GP, I have been able to plan a route which seems at last to be positive and I feel I should post a note on my current situation. I am 3 months+ since my last DA rotigotine patch and at which point
Thanks to the support of several contributors to this forum and especially Joolsg, LotteM, and my patient GP, I have been able to plan a route which seems at last to be positive and I feel I should post a note on my current situation. I am 3 months+ since my last DA rotigotine patch and at which point
davchar23
in
Restless Legs Syndrome
9 months ago
Mirapex
hi! My first post… just finding out about the dangers of this drug today and I’m in a bit of shock. I was taken off the medication abruptly without warning or notice of side effects/ withdrawal. I have been in agony but thinking it was in my head. how long does one need to be on this med to have damage
hi! My first post… just finding out about the dangers of this drug today and I’m in a bit of shock. I was taken off the medication abruptly without warning or notice of side effects/ withdrawal. I have been in agony but thinking it was in my head. how long does one need to be on this med to have damage
Booandzero75
in
Restless Legs Syndrome
9 months ago
park_bear made a very compelling argument for taking P5P (active B6)
park_bear made a very compelling argument for taking P5P (active B6)(a). My comments are: 1) When I tried taking (his recommended) 2 hours after C/L, I started walking side to side and the problem didn’t clear until I took my C/L again. 2) I am afraid to take P5P before bed because I did not sleep
park_bear made a very compelling argument for taking P5P (active B6)(a). My comments are: 1) When I tried taking (his recommended) 2 hours after C/L, I started walking side to side and the problem didn’t clear until I took my C/L again. 2) I am afraid to take P5P before bed because I did not sleep
Gcf51
in
Cure Parkinson's
9 months ago
buprenorphine study
Just wondering what people think about the recent study below? Study population was people with opioid use disorder (OUD) who are taking buprenorphine to manage it. Apparently an unusually high percentage of participants had RLS symptoms. I thought Bup alleviated symptoms? I’m in the process of getting
Just wondering what people think about the recent study below? Study population was people with opioid use disorder (OUD) who are taking buprenorphine to manage it. Apparently an unusually high percentage of participants had RLS symptoms. I thought Bup alleviated symptoms? I’m in the process of getting
707twitcher
in
Restless Legs Syndrome
9 months ago
Need your feedback and suggestions = please review the video and comment
I came across an enlightening YouTube video featuring Dr. Jonathan Sackner-Bernstein -------------paste [https:] then add [//youtu.be/k703Shlgkhw?si=iuLPYvtohxJ-Q3pQ] ---------------, prompting me to discontinue my use of LD medication. Note - the modarator has a heavy french accent - you
I came across an enlightening YouTube video featuring Dr. Jonathan Sackner-Bernstein -------------paste [https:] then add [//youtu.be/k703Shlgkhw?si=iuLPYvtohxJ-Q3pQ] ---------------, prompting me to discontinue my use of LD medication. Note - the modarator has a heavy french accent - you
RioIsHerName
in
Cure Parkinson's
9 months ago
Has anyone tried “compassionate use” or “right to try” laws?
I’m getting pretty desperate here as hubby can no longer tolerate any dopamine therapy. He’s only 61, can barely speak or walk, and I have to help him with almost everything. There’s actually not much out there on the horizon, but considering trying it with Buntanetap or neflamapimod (for Lewy Body
I’m getting pretty desperate here as hubby can no longer tolerate any dopamine therapy. He’s only 61, can barely speak or walk, and I have to help him with almost everything. There’s actually not much out there on the horizon, but considering trying it with Buntanetap or neflamapimod (for Lewy Body
LeharLover62
in
Cure Parkinson's
9 months ago
Pregabalin -mode of operation
I take 150mg per day (one dose at night) of pregabalin as a RLS "blocker". I have read Professor Earley's (Harper college in USA) paper on dopamine receptors etc and the various parts of the brain and would be interesting to know how pregabalin "fits" with this story? Thanks for listening Davchar
I take 150mg per day (one dose at night) of pregabalin as a RLS "blocker". I have read Professor Earley's (Harper college in USA) paper on dopamine receptors etc and the various parts of the brain and would be interesting to know how pregabalin "fits" with this story? Thanks for listening Davchar
davchar23
in
Restless Legs Syndrome
9 months ago
Role of Dopamine and Brain Iron stores
How is it known/thought that dopamine plays a role in RLS? So, is there a test for this or research to confirm scientifically that it is playing a role? Also, how is it known/ thought that brain iron stores play a role?
How is it known/thought that dopamine plays a role in RLS? So, is there a test for this or research to confirm scientifically that it is playing a role? Also, how is it known/ thought that brain iron stores play a role?
Edengirl58
in
Restless Legs Syndrome
9 months ago
Benfotiamine In The Mix For PD Again?
The following new animal study (December 2023) suggests that the fat soluble form of vitamin B1, Benfotiamine, may also be suitable for PD : https://www.sciencedirect.com/science/article/abs/pii/S0014299923007483?via%3Dihub Here is a relevant study quote :
' The results demonstrated that treatment
The following new animal study (December 2023) suggests that the fat soluble form of vitamin B1, Benfotiamine, may also be suitable for PD : https://www.sciencedirect.com/science/article/abs/pii/S0014299923007483?via%3Dihub Here is a relevant study quote :
' The results demonstrated that treatment
chartist
in
Cure Parkinson's
9 months ago
How to use the prone position more efficiently
In a post on HealthUnlocked https://healthunlocked.com/rlsuk/posts/150167349/could-this-be-why-some-of-us-have-less-rls-while-sleeping-in-the-prone-position?responses=150181979&utm_source=notification&utm_medium=email&utm_campaign=email_individual_response , it's mentioned that the prone position is
In a post on HealthUnlocked https://healthunlocked.com/rlsuk/posts/150167349/could-this-be-why-some-of-us-have-less-rls-while-sleeping-in-the-prone-position?responses=150181979&utm_source=notification&utm_medium=email&utm_campaign=email_individual_response , it's mentioned that the prone position is
VladimirF
in
Restless Legs Syndrome
10 months ago
Suffering like hell since I tried to taper off a dopamin agonist
Hi all, From Feb to Aug, I succesfully tapered off Venlafaxine extended release that I had taken for 28 years. I had started taking this medicine when I was 20 after what was probably a post-traumatic stress episode diagnosed as 'fibromyalgia' by my doctors back at that time. I tried several times to
Hi all, From Feb to Aug, I succesfully tapered off Venlafaxine extended release that I had taken for 28 years. I had started taking this medicine when I was 20 after what was probably a post-traumatic stress episode diagnosed as 'fibromyalgia' by my doctors back at that time. I tried several times to
Mikatrap
in
Restless Legs Syndrome
10 months ago
New therapies for RLS!! New research finally!
I have had RLS for 30 years, but when prescribed pramaprexole, of course, it made the monster worse. I did some research and there are two new therapies coming out. One is a new drug discovered by professor Dr. Stefan Clemens at Brody school of medicine...he discovered why augmentation happens...
I have had RLS for 30 years, but when prescribed pramaprexole, of course, it made the monster worse. I did some research and there are two new therapies coming out. One is a new drug discovered by professor Dr. Stefan Clemens at Brody school of medicine...he discovered why augmentation happens...
beartoothgirl406
in
Restless Legs Syndrome
10 months ago
Vitamin B2 Deficiency Can Cause B6 Toxicity! PWP Are Commonly Deficient In B2.
Vitamin B6 recycling. Image credit https://www.frontiersin.org/files/Articles/276491/fneur-08-00333-HTML/image_m/fneur-08-00333-g002.jpg From: https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2017.00333/full Vitamin B6 is a coenzyme required for over 100 different biochemical transformations
Vitamin B6 recycling. Image credit https://www.frontiersin.org/files/Articles/276491/fneur-08-00333-HTML/image_m/fneur-08-00333-g002.jpg From: https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2017.00333/full Vitamin B6 is a coenzyme required for over 100 different biochemical transformations
park_bear
in
Cure Parkinson's
10 months ago
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