Experiences with

Dopexamine

It feels different at every stage of its evolution, but once it really is established, I think it feels like the brake pad on the bicycle is rubbing on the tire and one has to pedal against this friction all day long. You can do it but knowing that it's going to be a lot of work to maintain forward motion

https://www.youtube.com/watch?v=KWKH286hheQ

https://aasm.org/aasm-fellow-listing/ The wonderful Dr Andy Berkowski has been named a fellow of the AASM. Well deserved. We have Dr Berkowski to thank for the recent changes to UK NICE cks guidance. They based their changes on Dr Berkowski's recent AASM guidance which effectively relegated dangerous

Greetings to one and all from Taipei City, Taiwan. 64 years old male, first sleep study 2015: sleep apnea - CPAP therapy, successful [atrial regurgitation (leaky valve)]. RLS, PLMD, myoclonus nocturnus - Clonazepam [tapering up to 0.5mg./night to date], Pramipexole [0.125mg./night from September 2024

A very interesting interview with Dr Jonathan Sackner-Bernstein on the Parkinsons Education Podcast. He has a trial going at the moment where he uses a L Tyrosine inhibitor (Called RB190, if I recall correctly ) to treat PD. RB190 has already been approved by the FDA for other treatment. https://www.youtube.com

Met some guy on Instagram months ago. He has a page about Bulgarian history, i was just on my main page with just posting like a blog, selfies, sometimes photos and memes. I need this dopamine from scrolling and from validation. I need someone to talk to. I need support. Years im struggling. My dad left

I am returning to this site again as I am enormously grateful for all of the stories/comments/etc. Since Sept. 2024 when I was down to 1 mg. of Pramipexole, I am now taking .4375 mg divided into .125 increments starting at 4 p.m. (.25 mg + 3/4 of second .25 mg). I am also taking 200 mg Pregabalin and

Hello everyone. I hope as you read this your legs are calm and settled and that your life is good. I've suffered with RLS for about 20 years and as it has progressed my life has gone into the toilet. I presently employ Neupro Rotigotine 2 mg patch to treat it and prior to the patch I took Ropinirole

Why Levodopa and Dopamine Medicines Should Be Avoided in Parkinson’s Disease: A Deeper Ayurvedic Perspective ❌ Krauncha seeds (Mucuna) contain L-Dopa but do not stop neuron degeneration. This can be a herbal claim- not ayurvedic. ❌ It follows the same temporary relief mechanism as synthetic Levodopa

I have had leg pain for a number of years. My movement disorder specialist has insisted that this is not a symptom of Parkinson's. In any case, I had my general practitioner put me on gabapentin to see if that would help with the pain. It actually helped for a short time, but then it stopped working-

I’m 61 and have pretty good health insurance in the United States. I see an internist, a sleep neurologist, and a psychiatrist (the latter necessary because of medication side effects.) Long story short: Klonopin was helpful for many years; they want me off Neupro; Suboxone just kept me spacey and in

When initially diagnosed, we start our medications from dopamine agonists, anticholinergics, and other anti-Parkinson's medicines and then off course the levodopa. The neurologists and movement disorder specialists mere add a new medicine to patient daily regime upon complaints of new symptoms. They

Does anyone have experience of DAWS Is it possible for PWP to experience DAWS stopping Sifrol (pramipexole) 0.75 mg cold turkey Wanting opinions - YES. NO.

Following my appearance on GMB yesterday, reading Twitter/X (I know I shouldn’t) just goes to show how far we still have to go to educate ‘stupid, judgmental, naive’ people (although they probably can’t be). It’s really annoyed me to be honest, I know that’s silly. My son tried trolling some of the

I just wanted to say to every one of you that has sent a message over the past few days a huge ‘THANK YOU’ for your encouragement and kind words. As I am sure you can imagine, it wasn’t easy to ‘go public’ with my story, but reading this forum over the years, and feeling the anguish that so many people

Hello fellow sufferers, I've got a specific question that I'm wondering if anybody else in here has ever had to consider: I am a long time sufferer of rls who has progressed into augmentation using DAs and was able to almost completely get off them replacing them with Gabapentin and low dose opiates

Joined just to share this in hopes that it can offer a deeper look into getting off dopamine agonists and what it entails for people. I've never seen anyone online post a thorough log as to what getting off these meds is like and how they did it, so here is mine. Background Some context, I have been

Has anyone tried velvet beans or velvet bean supplements as they are supposed to boost dopamine levels. If so, what was your experience of them. Many thanks in advance

Anyone dealing with depression ever get tested genetically and find you have FAST COMT Val/Val. This gene allegedly leads to low dopamine and low norepinephrine in the brain. My symptoms have always been low energy, slow cognitive tempo, brain fog, low mood, poor recall memory, poor motivation (

From what we all observe here, most general practitioners and some neurologist are not approaching the treatment of RLS according to what is now the accepted protocol. But who is asking why? For many of us we just want to get better and this question does not matter. But for some who are concerned