Search
Search
About
Log in
Join
Experiences with
Cetuximab
Posts
Communities
2,439 public posts
Filter results
Duvelisib + FCR (DFCR) frontline therapy for younger CLL patients - study results (Aug. 2020)
"In summary, our phase 1b/2 study identified a recommended phase 2 dose of duvelisib 25 mg bid when given in combination with FCR in younger CLL patients receiving frontline therapy. We observed deep responses, including achievement of BM-uMRD in about two-thirds of patients,irrespective of IGHV mutation
"In summary, our phase 1b/2 study identified a recommended phase 2 dose of duvelisib 25 mg bid when given in combination with FCR in younger CLL patients receiving frontline therapy. We observed deep responses, including achievement of BM-uMRD in about two-thirds of patients,irrespective of IGHV mutation
avzuclav
in
CLL Support
4 years ago
Schematic for CLL treatment?
Is there a decision chart or list of questions somewhere on this forum for how docs make their decisions?(am not talking the nhs system who seem to just offer you fcr to start with as a default regardless as far as I can make out - more like a doc who had all options open). Thanks very much.
Is there a decision chart or list of questions somewhere on this forum for how docs make their decisions?(am not talking the nhs system who seem to just offer you fcr to start with as a default regardless as far as I can make out - more like a doc who had all options open). Thanks very much.
Research123
in
CLL Support
4 years ago
Final treatment free day
I have one last day before starting FCR. The to do list includes a coastal bike ride, a conquer of a hill and the making of a large Sherry trifle plus a full English.* How did you spend that last ‘normal’ day? *Plans subject to change 😊😊(slight 😥 eek)
I have one last day before starting FCR. The to do list includes a coastal bike ride, a conquer of a hill and the making of a large Sherry trifle plus a full English.* How did you spend that last ‘normal’ day? *Plans subject to change 😊😊(slight 😥 eek)
HarryMet
in
CLL Support
4 years ago
Want to take advantage of all our features? Just log in!
Log in
or
Join
Spleen removal
My daughter 28 was terrified to have her spleen removed and went through hell in for 1 yr. blood work was checked every week, besides the prednisone in basic treatment 4 rounds of rituximab was given(by the way if 1 round doesn't work don't let them prescribe more) platlet count only when up when
My daughter 28 was terrified to have her spleen removed and went through hell in for 1 yr. blood work was checked every week, besides the prednisone in basic treatment 4 rounds of rituximab was given(by the way if 1 round doesn't work don't let them prescribe more) platlet count only when up when
Espomom
in
ITP Support Association
4 years ago
SF3B1 Mutations
We've had a couple of members mention that they are positive for SF3B1 Mutations so I thought it would be worth a short simplified post about it. SF3B1 are predominantly sub clonal genetic events in CLL and are not unique to CLL as they are also found in other haematological disease such as myelodysplastic
We've had a couple of members mention that they are positive for SF3B1 Mutations so I thought it would be worth a short simplified post about it. SF3B1 are predominantly sub clonal genetic events in CLL and are not unique to CLL as they are also found in other haematological disease such as myelodysplastic
Jm954
Administrator
in
CLL Support
4 years ago
Rituxamab Infusion
Hi. I had my first Rituximab infusion yesterday. Was very breathless last night and had the most awful chills. One minute I was changing my pjs as they were soaked through with sweat, the next I was dithering and couldn’t get warm. I was also on the loo needing to urinate every 20 mins and feel shaking
Hi. I had my first Rituximab infusion yesterday. Was very breathless last night and had the most awful chills. One minute I was changing my pjs as they were soaked through with sweat, the next I was dithering and couldn’t get warm. I was also on the loo needing to urinate every 20 mins and feel shaking
SammyJ
in
LUPUS UK
4 years ago
FCR oral versus iv
Hi I have read that cyclophosphamide and fludarabine can be given orally instead of IV. Is oral better tolerated in terms side effects? I guess oral formulation avoids need to attend hospital more frequently for infusions too. Is there anything else I should consider if needing tx with FCR? Thanks
Hi I have read that cyclophosphamide and fludarabine can be given orally instead of IV. Is oral better tolerated in terms side effects? I guess oral formulation avoids need to attend hospital more frequently for infusions too. Is there anything else I should consider if needing tx with FCR? Thanks
CarpeDiem03
in
CLL Support
4 years ago
Does FCR cause hair loss?
Drear group Does FCR cause hairs doss? And is FCR pain full ? Thank you
Drear group Does FCR cause hairs doss? And is FCR pain full ? Thank you
Nour80Leen2011
in
CLL Support
4 years ago
day 1 fcr ,,but un-mutated
hi thankyou for all your replys,well it was day 1 today on fcr everything went smooth day 2 tommorow hope it goes the same ,today i asked the nurse what my mutation was she replayed and said im un-mutated now is it ok to be on fcr if you are unmutated just made me feel a bit worried i asked her before
hi thankyou for all your replys,well it was day 1 today on fcr everything went smooth day 2 tommorow hope it goes the same ,today i asked the nurse what my mutation was she replayed and said im un-mutated now is it ok to be on fcr if you are unmutated just made me feel a bit worried i asked her before
kel555
in
CLL Support
4 years ago
Lupus Medication
I have had lupus for 16 years and have been struggling during this time with different drugs and their side effects. I have retinopathy caused by Chloroquine so cant take that. I am getting really worried as I am quickly running out of options. My rhemy is now suggesting Rituximab and Ciclosporin. Has
I have had lupus for 16 years and have been struggling during this time with different drugs and their side effects. I have retinopathy caused by Chloroquine so cant take that. I am getting really worried as I am quickly running out of options. My rhemy is now suggesting Rituximab and Ciclosporin. Has
littlemissp
in
NRAS
4 years ago
After Rixtuximab and Bendamustine - what next???
Hello everyone, I hope you are all staying safe, physically and mentally. My partner, Phil finished his 6 courses of Rituximab and Bendamustine, about 3 weeks ago. He has had a scan and we will be seeing the Consultant this Friday 26th June. He is experiencing some stomach pain and a high volume
Hello everyone, I hope you are all staying safe, physically and mentally. My partner, Phil finished his 6 courses of Rituximab and Bendamustine, about 3 weeks ago. He has had a scan and we will be seeing the Consultant this Friday 26th June. He is experiencing some stomach pain and a high volume
pollyg2016
in
Non Hodgkin's Lymphoma Friends
4 years ago
Rituximab wearing off too soon
I had my first two infusions in January and waited patiently for signs of improvement. Thanks to asking here, I knew it could take 3-4 months. Sure enough in early May I rapidly began to feel better and had a fantastic May with almost no pain, stiffness or fatigue. Life felt normal. Then 2 weeks ago
I had my first two infusions in January and waited patiently for signs of improvement. Thanks to asking here, I knew it could take 3-4 months. Sure enough in early May I rapidly began to feel better and had a fantastic May with almost no pain, stiffness or fatigue. Life felt normal. Then 2 weeks ago
mhlmom
in
NRAS
4 years ago
Question - please,and thanks to all for your support this week! Is BMB always necessary before starting treatment?
Good news all, husband back in hands of prior oncologist at Baptist. Treating the AIHA with blood transfusions and Rituximab. Discussed if need to treatment would be Venetoclax and Gazyva - hurray! However, since my one issue with this doctor is his desire to have often BMB's, can't the blood tests
Good news all, husband back in hands of prior oncologist at Baptist. Treating the AIHA with blood transfusions and Rituximab. Discussed if need to treatment would be Venetoclax and Gazyva - hurray! However, since my one issue with this doctor is his desire to have often BMB's, can't the blood tests
Palmetto
in
CLL Support
4 years ago
ASCEND: Acalabrutinib Versus Idelalisib Plus Rituximab or Bendamustine Plus Rituximab in R/R CLL
Take home message is that Acalabrutinib significantly improved PFS and that Idelalisib Plus Rituximab treatment was associated with a high level of serious adverse events compared to the other treatments.
310 patients were randomly assigned to acalabrutinib monotherapy (n = 155) or investigator
Take home message is that Acalabrutinib significantly improved PFS and that Idelalisib Plus Rituximab treatment was associated with a high level of serious adverse events compared to the other treatments.
310 patients were randomly assigned to acalabrutinib monotherapy (n = 155) or investigator
Jm954
Administrator
in
CLL Support
4 years ago
Venetoclax and Rituximab to achieve MRD?
My brother is on venetoclax monotherapy and he is found to start 6 cicles of Rituximab also. He is on the 400 mg dose of venetoclax now and his blood works are good. No nodes. Its possible to have MRD in the cases of 17p tp53 cll patients with this treatment? All of your knowledge and experiences are
My brother is on venetoclax monotherapy and he is found to start 6 cicles of Rituximab also. He is on the 400 mg dose of venetoclax now and his blood works are good. No nodes. Its possible to have MRD in the cases of 17p tp53 cll patients with this treatment? All of your knowledge and experiences are
Cgr2018
in
CLL Support
4 years ago
Go off imbruvica
Hello! My brother it’s now on 400 mg of venetoclax, for 2 weeks. All the nodes dessapeared and the blood levels are good. Because he relapsed on imbruvica, at the 50 mg dose, the doctors put him off imbruvica, in the 50 mg dose and in few days the nodes increased quickly and had fever. So the doctors
Hello! My brother it’s now on 400 mg of venetoclax, for 2 weeks. All the nodes dessapeared and the blood levels are good. Because he relapsed on imbruvica, at the 50 mg dose, the doctors put him off imbruvica, in the 50 mg dose and in few days the nodes increased quickly and had fever. So the doctors
Cgr2018
in
CLL Support
4 years ago
Need advice and what to expect
Hi All Lupus Warriors I need some advice what to expect when I go for my treatment next month rituximab treatment it’s my first dose please. What to take with me to hospital when I’m sat there for 6 hours. Any advice would be grateful Thank you Carmen x
Hi All Lupus Warriors I need some advice what to expect when I go for my treatment next month rituximab treatment it’s my first dose please. What to take with me to hospital when I’m sat there for 6 hours. Any advice would be grateful Thank you Carmen x
carmen85
in
LUPUS UK
4 years ago
Show I aim to try to walk with this condition
Good morning Looking for advice on walking.... I was diagnosed with CLL November 2019 from a routine blood test. It progressed much quicker than I had expected and by May 2020 as a result of FISH test and 94% 11q deletion, FCR was recommended. However two weeks later I went for routine eye test sent
Good morning Looking for advice on walking.... I was diagnosed with CLL November 2019 from a routine blood test. It progressed much quicker than I had expected and by May 2020 as a result of FISH test and 94% 11q deletion, FCR was recommended. However two weeks later I went for routine eye test sent
Caoimh37
in
Couch to 5K
4 years ago
FCR veterans
hi all iam due to start fcr on the 11 august on flair trial not realy happy due to the covid ,well my question is will it work i have been on w&w for 7yrs i have no tp53 and others and i dont know if iam mutated or un mutated could i be mutated if i have had cll for this long, realy need some answers
hi all iam due to start fcr on the 11 august on flair trial not realy happy due to the covid ,well my question is will it work i have been on w&w for 7yrs i have no tp53 and others and i dont know if iam mutated or un mutated could i be mutated if i have had cll for this long, realy need some answers
kel555
in
CLL Support
4 years ago
Ritx
Hi. So as everyone’s rituximab been stopped I’m sure I seen read on here someone had it few weeks ago.. I had a phone conversation with the consultant today told to still shield due to ritx been on the list of covid drugs and they will be changing my drugs in July.. she also said steroid can enhance
Hi. So as everyone’s rituximab been stopped I’m sure I seen read on here someone had it few weeks ago.. I had a phone conversation with the consultant today told to still shield due to ritx been on the list of covid drugs and they will be changing my drugs in July.. she also said steroid can enhance
Vonnie10
in
NRAS
4 years ago
1
...
34
35
36
...
100
Next page
10
20
30
40
50
60
70
80
90
100
Filter results
Clear filters
Posted in
All communities
CLL Support
990 results
NRAS
554 results
Vasculitis UK
325 results
View top 10 communities
Sort by
Most Relevant
Newest