ok, i'm just looking for some guidance here. Firstly some background. I am male 57yrs a bit overweight all around belly! I have been off and on antidepressants for 25yrs and in the early years they did make a difference as I believe I was depressed owing to certain things but I would say the last 15 yrs at least they haven't made any difference to my feeling of wellbeing.
I have just not felt right in myself for a very long time. I wouldn't say depressed as I know what that feels like but more just feeling totally knackered with really bad brain fog, memory seems bad and commented on by other people, lack of concentration, feel very weak, find it sometimes impossible to deal with two things at the same time and needing to sleep often twice during the day etc. . I get these symptoms even when feeling generally happy but the severity of these symptoms seem to vary from day to day.
On top of this for years I have suffered from impotence and lack of libido which has got me very down at times. I should say this was even during periods of not being on AD's. All this over time has cost me my marriage, a job and literally thousands of pounds on non working days due to the above symptoms.
Unfortunately I have one of those doctors that puts everything down to depression and hand out the pills like sweets.
Anyway having just really lost faith in my doctor and basically giving up on life I decided to take things into my own hands and get some blood test done (thyroid, testosterone and vitamins) privately and had some interesting results.
TSH 2 mIU/L range 0.27 -- 4.20
Free T4 15.8 pmol/L range 12 -- 22
Total T4 77.6 nmol/L range 59 -- 154
Free T3 4.26 pmol/L range 3.1 -- 6.8
Thyroglobulin 9.0 IU/mL antibody range 0.0 -- 118
TOP antibodies *37.5 IU/mL range 0.0 -- 34
Vitamin B12 148 Pmol/L 140 --724
Folate 4.36 ug/L 2.91 ----- 50
Vitamin D * 28.7 nmol/L 50 ---- 200
Ferritin 202 ug/L 30 --- 400
CRP High Sensitivity 1.2 mg/L 0.00 --- 5
HAEMOGLOBIN (G/L) *173 g/L 130.00 - 170.00
HCT *0.506 L/L 0.37 - 0.50
RED CELL COUNT 5.26 x10^12/L 4.40 -5.80
MCV 96 fl 80.00 -99.00
MCH 32.9 pg 26.00 -33.50
MCHC (G/L) 342 g/L 300.00 -350.00
RDW 12.4 % 11.50 - 15.00
WHITE CELL COUNT 5.4 x10^9/L 3.00 -10.00
NEUTROPHILS 3.24 x10^9/L 2.00 -7.50
LYMPHOCYTES 1.32 x10^9/L 1.20 -3.65
MONOCYTES 0.52 x10^9/L 0.20 -1.00
EOSINOPHILS 0.27 x10^9/L 0.00 -0.40
BASOPHILS 0.05 x10^9/L 0.00 -0.10
D.H.E.A. SULPHATE 11.410 umol/L 0.44 - 13.40
FOLLICLE STIM. HORMONE 3.55 IU/L 1.50 - 12.40
LUTEINISING HORMONE 5.97 IU/L 1.70 - 8.60
TESTOSTERONE 14.96 nmol/L 7.60 - 31.40
FREE-TESTOSTERONE(CALCULATED) *0.219nmol/L 0.30 - 1.00
SEX HORMONE BINDING GLOB 54.82 nmol/L 19.00 - 83.00
FREE ANDROGEN INDEX 27.29 Ratio 24.00 - 104.00
BETA OESTRADIOL 72.72 pmol/L 0.00 - 191.99
I am sure the results that stick out on this forum will be the Vitamins. I should say that my doctor when shown the results said that my B12 was "absolutely fine". Luckily I was prepared and so read out the NICE guidelines to him so he gave in and I have just had my 4th B12 loading injection this morning and he prescribed high dose Vitamin D pills. I am certainly feeling a difference in energy.
From the Thyroid forum I understand I have Hashimoto's because of elevated TPO and I know that having the low free testosterone is not good as far as anything sexual goes. I have done quite a bit of research and know there is a good chance I have Pernicious Anaemia so have also started a gluten free diet which I immediately felt the benefits of. I am also taking Folate supplement but not really sure how much I should take
It wont surprise you that I am going to change my doctor.
Now from what I have read, B12 has an impact on all of these problems. Ie. thyroid has an effect on B12 then you read that low B12 has an effect on Thyroid and also that both have an effect on testosterone.
I am really not sure what my next step should be! What test's should I insist on when seeing another doctor? And in what order?
I have not done enough research to really understand the Haematology results so any help there would be gratefully received. (doctor made no comment on them)I haven't included cholesterol results but I know they are quite high.
Many thanks in advance for your time with this