Posts - Advanced Prostate Cancer | HealthUnlocked

Advanced Prostate Cancer

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Dad’s latest blood results - PSA down , ALP down , T up

Got dad’s blood work done after almost 8 weeks. Last tests were done on 23 July when he was only on orgovyx. At the time his PSA was 1.177 , testosterone...

Got dad’s blood work done after almost 8 weeks. Last tests were done on 23 Jul...

Tinkudi

•6 hours ago

6 Replies

If PSA decreases in MHsPC but ALP increases , is one still castrate sensitive ?

I know that PSA decreasing or remaining steady while on hormone therapy means one is hormone sensitive but if PSA decreases but ALP increases , does that still...

I know that PSA decreasing or remaining steady while on hormone therapy means on...

Tinkudi

•14 hours ago

8 Replies

Does ADT work only on bone mets or organ mets also ?

Just trying to learn. Often I read that when someone is discovered with an organ Met like liver etc , they start on chemotherapy too. Do ADT and ARPI also...

Just trying to learn. Often I read that when someone is discovered with an org...

Tinkudi

•16 hours ago

2 Replies

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Traveling During Treatment

My husband who had Brachytherapy 9/11 and started Zytega this month along with Orgovyx which he started in July is scheduled for IGMRT in October. We are...

My husband who had Brachytherapy 9/11 and started Zytega this month along with O...

SherryKahn

•18 hours ago

4 Replies

Ok to do brisk walking before doing psa test ?

Is it ok to do brisk walking just before doing a PSA test. I know One should avoid cycling for a couple of days.

Is it ok to do brisk walking just before doing a PSA test. I know One should a...

Tinkudi

•18 hours ago

2 Replies

Starting Orgovyx and Nubeqa. Your experience?

Curious to know your side effects, what you did to deal with them, anything expected or unexpected, plusses and minuses? Thanks in advance.

Curious to know your side effects, what you did to deal with them, anything expe...

KMY28

•20 hours ago

12 Replies

Step 2 - mpMRI done, results not good, I'm scared now

Hi all, I've been enjoying following many of your stories and it has helped me prepare for this journey. Thanks to everyone who graciously shares and responds...

Hi all, I've been enjoying following many of your stories and it has helped me ...

RazorSaw

•21 hours ago

8 Replies

Pluvicto

Are there any cases or studies that demonstrate long term remission or complete prostate cancer elimination following Pluvicto or other radio pharmaceuticals?...

Are there any cases or studies that demonstrate long term remission or complete ...

NDJIM

•21 hours ago

5 Replies

PLEASE DONATE.

Here is a post from 6 days ago, authored by Darryl. Keep your support in your community. While other so-called nonprofits flood you with robocalls,...

Here is a post from 6 days ago, authored by Darryl. Keep your support in your c...

j-o-h-n

•23 hours ago

11 Replies

3 months post ADT ending checkup

Just completed my checkup after ending ADT in May. My doctor was looking to schedule a PSMA scan to build a baseline. Since I was diagnosed Gleason 9 there is...

Just completed my checkup after ending ADT in May. My doctor was looking to sche...

chefjlu

•1 day ago

7 Replies

Started treatments in August 2024 and wondered about PSA numbers?

Started treatments in August 2024 and am monitored every two weeks due to Potassium level always going up. Remedied with a bag of fluids to help with any...

Started treatments in August 2024 and am monitored every two weeks due to Potass...

PARKER3237

•1 day ago

2 Replies

Apricot seeds/B17 and Prostate Cancer

Yesterday my Optometrist buddy said he found that apricot seeds prevent prostate cancer but I do not see anything substantial on it- anyone else?

Yesterday my Optometrist buddy said he found that apricot seeds prevent prostate...

jackwfrench

•1 day ago

17 Replies

When CRISPR is not enough, virtual CRISPR comes to aid! CREME, an AI-powered virtual lab

Creme de la creme...ok, bad one but I could not resist! Basically since CRISPR (even if it's a FANTASTIC tool) takes time and money, why not simulate it so we...

Creme de la creme...ok, bad one but I could not resist! Basically since CRISPR ...

Maxone73

•1 day ago

1 Reply

Nonmetastatic castrate resistant prostate cancer

I have been on hormone therapy for 10 years with stage 3 non-metastatic prostate cancer. Now I am very close to doubling the PSA < 10 months. Question. What...

I have been on hormone therapy for 10 years with stage 3 non-metastatic prostate...

Varsin

•2 days ago

4 Replies

ESMO 2024: Xaluritamig (AMG 509), a STEAP1 x CD3 XmAb 2+1 immune therapy for Metastatic CRPC: initial results of Phase 1

Xaluritamig, a novel bispecific T-cell engager targeting STEAP1, in patients with metastatic castration-resistant prostate cancer (mCRPC). STEAP1 is a cell...

Xaluritamig, a novel bispecific T-cell engager targeting STEAP1, in patients wit...

Maxone73

•2 days ago

Be the first to reply

Immunotherapy before/after or concurrent with Chemotherapy

Hii all , My father is failing ADT and next step is to start chemotherapy . I have discussed the case with APAC Biotech Gurugram regarding Immunotherapy ....

Hii all , My father is failing ADT and next step is to start chemotherapy . I h...

jeetu_g27

•2 days ago

6 Replies

Zytiga and diabetes

I’ve been on the Zytiga/Lupron/Prednisone cocktail for about 13 months now. In that time, my A1C has shot up to where now I have diabetes. Now I know this is a...

I’ve been on the Zytiga/Lupron/Prednisone cocktail for about 13 months now. In t...

BigJ32

•2 days ago

13 Replies

Good explanation of why drug prices in US are so high

This interview with Mark Cuban is a good explanation of why US drug prices are so high. The interview is mostly about politics, but from 19:57 -29:52 it's...

This interview with Mark Cuban is a good explanation of why US drug prices are s...

Tall_Allen

•2 days ago

9 Replies

Lupron cost!!!

LEUPROLIDE ACETATE INJECTION (45mg) 6 Month Description/Modifier Billing Code J9217 Provider billed the plan $35,367.50 Total cost (amount the plan...

LEUPROLIDE ACETATE INJECTION (45mg) 6 Month Description/Modifier Billing Code ...

Still_in_shock

•2 days ago

55 Replies

Moderna’s “off-the-shelf” solid tumour cancer mRNA vaccine shows promising results

Hope they are able to tackle PCa too with this: https://gizmodo.com/modernas-off-the-shelf-cancer-vaccine-shows-promise-in-early-human-trial-data-2000499098

Hope they are able to tackle PCa too with this: https://gizmodo.com/modernas-of...

Samrecan

•2 days ago

Be the first to reply

The Day I Raced My Palliative Care Nurse

I’m coming off the mountain top! What an incredible experience and I’m sure Nurse Sarah (not her real name) feels the same! I was smiling and laughing all...

I’m coming off the mountain top! What an incredible experience and I’m sure N...

TuffNuttoCrack

•2 days ago

11 Replies

Need Help NOW

Hello fellow fighters! My husband has recently finished 6 rounds of Pluvicto and his PSMA PET scan has shown considerable spread throughout his bones. His PSA...

Hello fellow fighters! My husband has recently finished 6 rounds of Pluvicto and...

Fighting4u

•2 days ago

27 Replies

ESMO 2024: Opevesostat (MK-5684/ODM-208) in metastatic CRPC updated CYPIDES phase 2 results

Not bad but you need a mutation! The trial enrolled 134 heavily pre-treated mCRPC patients who had progressed after at least one novel hormonal agent and one...

Not bad but you need a mutation! The trial enrolled 134 heavily pre-treated mCR...

Maxone73

•2 days ago

1 Reply

Beginning Pluvicto

My husband is having his first Pluvicto infusion in October. I am gathering as much information as possible so I can help him and, at the same time, try to...

My husband is having his first Pluvicto infusion in October. I am gathering as ...

Leigh1447

•2 days ago

22 Replies

ESMO 2024: phase 1/2 trial of oral masofaniten (EPI-7386) plus Enzalutamide compared to Enzalutamide alone in men with mCRPC

This looks promising. The trial enrolled 18 patients who were on androgen deprivation therapy but had not received prior AR pathway inhibitors; some had...

This looks promising. The trial enrolled 18 patients who were on androgen depri...

Maxone73

•2 days ago

1 Reply

ESMO 2024: TAMARACK, a randomized phase 2 trial of the B7-H3 targeting ADC Vobramitamab for metastatic CRPC

My sensation is that it is too early to say ho well it works, but SE look pretty harsh! The trial enrolled 181 men with mCRPC who had previously received one...

My sensation is that it is too early to say ho well it works, but SE look pretty...

Maxone73

•2 days ago

2 Replies

ESMO 2024 - UpFrontPSMA: randomized study of sequential 177Lu-PSMA-617 and Docetaxel vs Docetaxel in metastatic prostate cancer

Data about overall survival seems immature to me, it seems like there is a slight advantage for the sequential therapy, not very significant, but both arms at...

Data about overall survival seems immature to me, it seems like there is a sligh...

Maxone73

•2 days ago

Be the first to reply

Exercise boost aging immune system

From an internet search. Does exercise help the elderly immune system? Not only does exercise get the immune cells moving throughout the body during...

From an internet search. Does exercise help the elderly immune system? Not onl...

Derf4223

•2 days ago

5 Replies

ESMO 2024: Cabozantinib plus Atezolizumab versus 2nd novel hormonal therapy inmetastatic CRPC, overall survival results of CONTACT-02 Study

Basically, even if there was a prolonged progression-free survival, OS was not statistically different in the two arms. BUT a strong survival advantage was...

Basically, even if there was a prolonged progression-free survival, OS was not s...

Maxone73

•2 days ago

Be the first to reply

ESMO 2024: Phase 3 evaluation of transdermal estradiol vs LHRH agonists for androgen suppression

This is very interesting for us all, even if these results are for non metastatic patients! Results demonstrated that transdermal estradiol was non-inferior...

This is very interesting for us all, even if these results are for non metastati...

Maxone73

•2 days ago

30 Replies

Write a post or ask a question

Posts - Advanced Prostate Cancer | HealthUnlocked

Advanced Prostate Cancer

Dad’s latest blood results - PSA down , ALP down , T up

If PSA decreases in MHsPC but ALP increases , is one still castrate sensitive ?

Does ADT work only on bone mets or organ mets also ?

Traveling During Treatment

Ok to do brisk walking before doing psa test ?

Starting Orgovyx and Nubeqa. Your experience?

Step 2 - mpMRI done, results not good, I'm scared now

Pluvicto

PLEASE DONATE.

3 months post ADT ending checkup

Started treatments in August 2024 and wondered about PSA numbers?

Apricot seeds/B17 and Prostate Cancer

When CRISPR is not enough, virtual CRISPR comes to aid! CREME, an AI-powered virtual lab

Nonmetastatic castrate resistant prostate cancer

ESMO 2024: Xaluritamig (AMG 509), a STEAP1 x CD3 XmAb 2+1 immune therapy for Metastatic CRPC: initial results of Phase 1

Immunotherapy before/after or concurrent with Chemotherapy

Zytiga and diabetes

Good explanation of why drug prices in US are so high

Lupron cost!!!

Moderna’s “off-the-shelf” solid tumour cancer mRNA vaccine shows promising results

The Day I Raced My Palliative Care Nurse

Need Help NOW

ESMO 2024: Opevesostat (MK-5684/ODM-208) in metastatic CRPC updated CYPIDES phase 2 results

Beginning Pluvicto

ESMO 2024: phase 1/2 trial of oral masofaniten (EPI-7386) plus Enzalutamide compared to Enzalutamide alone in men with mCRPC

ESMO 2024: TAMARACK, a randomized phase 2 trial of the B7-H3 targeting ADC Vobramitamab for metastatic CRPC

ESMO 2024 - UpFrontPSMA: randomized study of sequential 177Lu-PSMA-617 and Docetaxel vs Docetaxel in metastatic prostate cancer

Exercise boost aging immune system

ESMO 2024: Cabozantinib plus Atezolizumab versus 2nd novel hormonal therapy inmetastatic CRPC, overall survival results of CONTACT-02 Study

ESMO 2024: Phase 3 evaluation of transdermal estradiol vs LHRH agonists for androgen suppression

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