New blood test results : Hello.I have just... - Thyroid UK

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New blood test results

ChickieBaker profile image
11 Replies

Hello.I have just received my latest Medichecks results and I'd like some guidance before seeing my doctor next week. I'll post the new ones along with the results from my previous test last May for comparison. I am currently on 75 Levothyroxine.

Feb 2025 May 2024

CRP. 5.77 4.33

Ferritin 249 234

Folate 16.2 10.8

B12 150 54

Vit D 170 105

TSH 3.960 mlU/L 0.758

Free T3. 3.9 pmol/L 3.9

Free Thyroxine 16.8 19.9

Thyroglobulin

Antibodies 363. 454

Thyroid

Peroxidase 122 169

I have recently moved to a new doctor's surgery so I don't know how knowledgeable and open minded they are going to be about thyroid issues and Hashimotos so I want to be prepared if you guys think I might need to increase my dosage . I took the blood test at least 24 hours after my medication with only water to drink.

Thanks in advance .

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ChickieBaker
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11 Replies
SlowDragon profile image
SlowDragonAmbassador

please add ranges on results for Ft4 and FT3 and folate and antibodies

presumably vitamin D is in nmol

ChickieBaker profile image
ChickieBaker in reply toSlowDragon

Free T3 range is 3.1-6.8Free thyroxine range is 12-22

Folate range is >7

Vit D is nmol

Thyroglobulin range is 0-115

Peroxidase range is 0-34

SlowDragon profile image
SlowDragonAmbassador in reply toChickieBaker

Free T4 (fT4) 16.8 pmol/L (12 - 22) 48.0%

Free T3 (fT3) 3.9 pmol/L (3.1 - 6.8) 21.6%

TSH over 2

See /contact GP and request 25mcg dose increase in Levo

Even if initially you only increase slowly as 75mcg and 100mcg on alternate days

Which brand of levothyroxine are you taking

Do you always get same brand at each prescription

Exactly what vitamin supplements are you taking

Vitamin D is rather high

Suggest you reduce dose a bit

ChickieBaker profile image
ChickieBaker in reply toSlowDragon

I take vit D drops so I could possibly reduce, I'll check with my naturopath. Ones of my Levo is Teva, can't remember the other as I don't have the box. I think I always get the same. I take Methyl Folgard which is folate and B12, I also take fish oils, turmeric, magnesium bisglycinate, glucosamine and sea buckthorn. If the doctor won't agree to an increase can I just slowly increase the dose myself ?

SlowDragon profile image
SlowDragonAmbassador in reply toChickieBaker

Teva brand upsets many people

Difficult to tell if that includes you if taking a mix

Which is Teva - the 25mcg or 50mcg

What’s the other one

Many people find Levothyroxine brands are not interchangeable.

Most easily available are Mercury Pharma or Accord

Mercury Pharma make 25mcg, 50mcg and 100mcg tablets 

Mercury Pharma also boxed as Eltroxin. Both often listed by company name on pharmacy database - Advanz

Accord only make 50mcg and 100mcg tablets. Accord is also boxed as Almus via Boots, 

Wockhardt is very well tolerated, but only available in 25mcg tablets. Some people remain on Wockhardt, taking their daily dose as a number of tablets 

July 2024

Crescent levothyroxine. Dosages: 12.5, 25, 50, 75, 100

(Not yet known if all approved dosages are or will be available).

Excipients: lactose monohydrate, maize starch, croscarmellose sodium, gelatin and magnesium stearate.

Lactose free brands - currently Vencamil or Teva

Vencamil is lactose free and mannitol free. originally only available as 100mcg only, but 25mcg, 50mcg and 75mcg tablets became available Sept 2024

Prior to March 2023 Vencamil was called Aristo

Vencamil often very well tolerated/best option for many people

How to get Vencamil stocked at your local pharmacy

healthunlocked.com/thyroidu...

Posts discussing Vencamil

healthunlocked.com/thyroidu...

healthunlocked.com/thyroidu....

Teva makes 12.5mcg 25mcg, 50mcg, 75mcg and 100mcg

Many patients do NOT get on well with Teva brand of Levothyroxine.

Teva is lactose free, but contains mannitol as a filler instead of lactose, which seems to be possible cause of problems. Mannitol seems to upset many people, it changes gut biome 

Helpful post about Teva

healthunlocked.com/thyroidu...

Posts that mention Teva

healthunlocked.com/search/p...

Teva poll

healthunlocked.com/thyroidu...

Relatively new ……Hillcross brand

This is a box, rather than a brand. 50mcg and 100mcg are Accord brand….but beware 25mcg is Teva brand

Helpful post about different brands

healthunlocked.com/thyroidu...

List of different brands available in U.K.

thyroiduk.org/if-you-are-hy...

Once you find a brand that suits you, best to make sure to only get that one at each prescription.

Watch out for brand change when dose is increased or at repeat prescription.

Government guidelines for GP in support of patients if you find it difficult/impossible to change brands

gov.uk/drug-safety-update/l...

If a patient reports persistent symptoms when switching between different levothyroxine tablet formulations, consider consistently prescribing a specific product known to be well tolerated by the patient.

academic.oup.com/jcem/artic...

Physicians should: 1) alert patients that preparations may be switched at the pharmacy; 2) encourage patients to ask to remain on the same preparation at every pharmacy refill; and 3) make sure patients understand the need to have their TSH retested and the potential for dosing readjusted every time their LT4 preparation is switched (18).

And here

pharmacymagazine.co.uk/clin...

Discussed here too

healthunlocked.com/thyroidu...

SlowDragon profile image
SlowDragonAmbassador in reply toChickieBaker

I take Methyl Folgard which is folate and B12

This one?

biocare.co.uk/nutrisorbr-me...

If the doctor won't agree to an increase can I just slowly increase the dose myself ?

You would quickly run out of levothyroxine if you did that

GP should agree to increase dose as TSH is over 2

List your hypo symptoms

Request “trial” increase

And retest in 2-3 months

approx how much do you weigh in kilo

Even if we frequently start on only 50mcg, most people need to increase levothyroxine dose slowly upwards in 25mcg steps (retesting 6-8 weeks after each increase) until eventually on, or somewhere near full replacement dose (typically 1.6mcg levothyroxine per kilo of your weight per day)

cks.nice.org.uk/topics/hypo...

bnf.nice.org.uk/drugs/levot...

nhs.uk/medicines/levothyrox...

Adults usually start with a dose between 50 micrograms and 100 micrograms taken once a day. This may be increased gradually over a few weeks to between 100 micrograms and 200 micrograms taken once a day.

Some people need a bit less than guidelines, some a bit more

TSH should always be below 2 on levothyroxine

gponline.com/endocrinology-...

Graph showing median TSH in healthy population is 1-1.5

web.archive.org/web/2004060...

Comprehensive list of references for needing LOW TSH on levothyroxine

healthunlocked.com/thyroidu....

onlinelibrary.wiley.com/doi...

If symptoms of hypothyroidism persist despite normalisation of TSH, the dose of levothyroxine can be titrated further to place the TSH in the lower part of the reference range or even slightly below (i.e., TSH: 0.1–2.0 mU/L), but avoiding TSH < 0.1 mU/L. Use of alternate day dosing of different levothyroxine strengths may be needed to achieve this (e.g., 100 mcg for 4 days; 125 mcg for 3 days weekly).

sciencedirect.com/science/a...

The optimal daily dose in overt hypothyroidism is 1·5–1·8 μg per kg of bodyweight, rounded to the nearest 25 μg.

ChickieBaker profile image
ChickieBaker in reply toSlowDragon

Sorry for the delay in replying, had to get my next batch of Levo from the pharmacist. Because a brand wasn't specified, this time I received 50mcg Hillcross ( Accord ) and 25mcg Mercury pharma. I have just started a dairy free trial to see if it helps my chronic bloating and constipation. Both my Levo have lactose and I couldn't change them but will ask my doctor to prescribe ones without lactose if it's absolutely necessary to change them. I can't imagine such a tiny amount will make a difference but I'm certainly no expert !!I weigh 70kg so by those rules I should be on closer to 112mcg so hopefully the doctor will allow a gradual increase.

I wonder whether being on a low dose is partially to blame for my immense bloating, distention and constipation ??

I have been 100% gluten free for a couple of years now.

SlowDragon profile image
SlowDragonAmbassador in reply toChickieBaker

I had been dairy free 2-3 years before I changed Levo to Vencamil (lactose free) ……personally I found noticeable improvement

Was already on lactose free T3

ChickieBaker profile image
ChickieBaker in reply toSlowDragon

I am due to see my doctor on Tuesday to try and rule out ovarian cancer as a cause of the bloating etc so can ask about lactose free Levo then. Also having a CT colonograph next month to see what's found. Perhaps looking at all these routes some of my symptoms might be helped. Thanks very much for all your advise 🙏

FancyPants54 profile image
FancyPants54 in reply toChickieBaker

Constipation is a symptom of hypo. As are bloating and sluggish digestion. You need more Levo.

ChickieBaker profile image
ChickieBaker in reply toFancyPants54

Thanks very much, let's just hope my new doctor agrees 😱🙏

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