I’ve been on previously, last year, with my daughters blood test results from medicheks.
Our Gp has just taken these bloods and here are the results. Could you please have a look and advise as she has a telephone call to discuss them.
Just a little reminder background information, she was diagnosed with ME at 15, she’s now 23.
She has many symptoms that cross over into hypothyroidism. We have lots of underactive thyroid in my family and I need to know if the doctors may be missing something, and just diagnosing with ME.
It was also suggested on here previously about pernicious anaemia, I’ve noticed her B12 levels to date, August 2022 are 165 and in December 2021 measured 212, (normal range, 180-2000.)
Here as follows are her results.
Thank you everyone, we so appreciate your knowledge and time.
31.8.22 test done at 8:30am no B vits for 7 days previous.
Serum c reactive protein
12mg. Normal range 0-5
Red blood cell count
4.55 ( 10.12/L) Normal range 3.8-5.5
Haemaglobin estimate
138gl Normal range 120-150
Haematocrit
0.418. Normal range 0.37-0.47
Mean corpuscular vol
92fl Normal range 80-100
Red blood cell distribution
12.4/. Normal range 0-16
Mean corpusc haemoglobin mch
30.4 pg. Normal range 27-32
Mean corpusc he. conc MCHC
331g/l. Normal range 280-350
Platelet count
269. Normal range 150-450
Total white cell count
10.1. Normal range 4-10
Neutrophil count
3.6. Normal range 1.8-7.5
Lymphocyte count
2.7. Normal range 1-4
Monocyte count
0.6. Normal range 0.2-1
Urea and electrolytes
Serum sodium
141. Normal range 133-146
Serum potassium
4.1. Normal range 3.5-5.3
Serum creatinine
66 Normal range 45-84
Serum urea
2.8. Normal range 2.5-7.8
CKDEPI
>90. Normal range 60-150
Serum vit B12
165 Normal range 180-2000
Serum folate
13.1. Normal range 3.1-18.3
Serum ferritin
109. Normal range 13-150
Thank you again
serum free T4
15.1 Normal range 11-24
Serum TSH
4.78 Normal range 0.35-4.5
1/12/21 TSH was 3.52
Written by
sunnyday7
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C Reactive Protein is over range and suggesting inflammation somewhere. It's a non- specific inflammation marker so can't tell us where the inflammation is.
Full Blood Count all looks good, no anaemia suggested.
Us & Es all in range.
Serum vit B12- 165 Normal range 180-2000
This is a concern being below range, it was very low in range previously.
According to an extract from the book, "Could it be B12?" by Sally M. Pacholok:
"We believe that the 'normal' serum B12 threshold needs to be raised from 200 pg/ml to at least 450 pg/ml because deficiencies begin to appear in the cerebrospinal fluid below 550".
"For brain and nervous system health and prevention of disease in older adults, serum B12 levels should be maintained near or above 1000 pg/ml."
Do she have any signs of B12 deficiency – check here:
If she does then list them to discuss with her GP and ask for testing for B12 deficiency and Pernicious Anaemia. Do not take any B12 supplements or folic acid/folate/B Complex supplements before further testing of B12 as this will mask signs of B12 deficiency and skew results and if you have B12 deficiency is not detected and treated then this could affect your nervous system. B12 deficiency should be treated before starting folic acid because folic acid can sometimes improve your symptoms so much that is masks B12 deficiency.
With such a low result I'd be surprised if she doesn't have any signs/symptoms and need B12 injections.
You could pop over to the Pernicious Anaemia forum here on Health Unlocked for further comments, listing all signs/symptoms she has as well as her test results (plus reference ranges) for B12 and folate:
Ferritin is raised when inflammation is present. Because her CRP is raised and showing inflammation then this ferritin result is likely to be unreliable, her true ferritin result is more than likely less than what has been measured - how much lower I can't say but here is a list of symptoms of low ferritin:
◾Weakness
◾Fatigue
◾Difficulty concentrating
◾Poor work productivity
◾Cold hands and feet
◾Poor short-term memory
◾Difficulty remembering names
◾Dizziness
◾Pounding in the ears
◾Shortness of breath
◾Brittle nails
◾Headaches
◾Restless legs
It would help if her GP does a full iron panel to include:
SlowDragon for info only sunyday7 Your daughters FT4 is only 31.54% through the range and her TSH is above range. She should be asking for more investigation into low B12.
once she gets B12 deficiency addressed by starting on B12 injections, very common for TSH to increase further and get diagnosed as hypothyroid and then start on levothyroxine
Low vitamins can mask how hypothyroid patient may be
she will initially need several injections over 2-3 weeks…(known as loading injections) ….
then it’s once every 2-3 months
They usually offer 3 monthly, but if that’s too long can request more frequent
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