NDT versus Levo/T3 & Vitamin support Advice

1 grain is equal, in its effect, to approx 100mcg of levo. Also dissolving under the tongue doesn't give you the effect you believe as the molecules in the NDT are too large to be absorbed by the tongue and you'd swallow most, when hormones have to be taken with a full glass of water so they dissolve in the stomach.

Also, I do know that some split doses but there's really no need as you'd have to find a window when your stomach is empty for the second dose, i.e. not to have eaten at least for 3 hours previously. Remember also that this will be a life-long process.

Reading the whole link might be helpful but particularly the response to the question dated January 30, 2002.

web.archive.org/web/2010103...

Usually, when switching from levo to NDT, it is an approx dose from levo to NDT. You stay on this dose for two weeks, (taking note of temp/pulse before beginning) and increase by a small dose (about 1/4 tablet) every two weeks with, hopefully, a slow but steady improvement in your clinical symptoms. (also levo has to slowly leave your system and would take a few weeks).

(I am not medically qualified but have hypothyroidism and have gone through the usual methods when not improving on levo).

If either pulse or temp rises too high, drop to previous dose.

I read a paper a few weeks back about taking T4 at night and as it's a storage hormone it doesn't matter when you take it. It was written by a team in Rotterdam and I was interested to see one of the authors was someone my late husband worked with many years ago. The paper was written a few years ago and mentioned that they don't think you could successfully take NDT at night so I'm going to try and get in touch with him and see if any work is being done on that. Obviously if I do find anything of interest that i am able to pass on I shall.