Can someone please comment on my recent blood results.

[lucylocks]

Currently taking 100mcg/125mcg levo alternately

Just got my blood results yesterday.

Receptionist said a note had been made to reduce levo to 75mcg although I am under the care of an endo

Made telephone appt. to discuss with G.P. for Monday

TSH 0.10 range 0.35 - 4.70

T4 14 range 7.80 - 21.00

Plasma viscosity 1.61 range 1.50 - 1.72

Haemoglobin estimation 141.0g/L range 120.00 - 160.00

Total white cell count 4.4 range 4.00 - 11.00

Platelet count 240 range 150.00 - 400.00

Red blood cell count 4.62 range 4.00 - 5.20

Haematocrit 0.417 range 0.36 - 0.46

MCV 90.3 range 80.00 - 100.00

MCH 30.5 range 26.00 - 34.00

Red cell distribution width 13.1 range 11.50 - 16.50

Neutrophil count 2.41 range 2.00 - 7.70

Lymphocyte count 1.53 range 0.80 - 3.40

Monocyte count 0.40 range 0.20 - 0.80

Eosinophil 0.08 range 0.04 - 0.40

Basophil count 0.02 range 0.01 - 0.10

Serum iron 16 range 8.00 - 34.00

Serum folate 9.0 no range Values <3.0ug/L deficient

Serum B12 394 range 180 - 1130

Serum ferritin 65 range 15.00 - 300

Serum C reactive protein level 2.6 range 0.00 - 8.00

Serum sodium 138 range 135.00 - 144.00

" potassium 4.2 range 3.50 - 5.30

chloride 103 range 96.00 - 109.00

bicarbonate 28 range 24.00 - 32.00

urea level 6.5 range 2.10 - 7.60

creatinine 76 range 51.00 - 107

GFR calculated abbreviated MDRD 68 mL/min/1.73m^2

Serum calcium 2.46 range 2.20 - 2.60

Corrected serum calcium level 2.42

Serum inorganic phosphate 1.35 range 0.70 - 1.50

" bilirubin level 22 range 7.00 - 23.00

alkaline phosphatase 81 range 30.00 - 125.00

ALT level 24 range 5.00 - 45.00

total protein 72 range 62.00 - 78.00

albumin 40 range 36.00 - 48.00

Waiting for Vit D result

Present symptoms, difficulty getting up in the morning, fatigue, general aches, hip bursitis, general anxiety

tingling in hands and feet, a couple of days recently whole body tingling and pricking, itching and numbness on right cheek and corner of lip.

I would greatly appreciate any comments.

Many thanks browny

[puncturedbicycle]

Why? I'm assuming the tsh is putting them off but your t4 is middling at best. And why suggest that it be reduced from 100/125 to 75??? It is only a tiny bit under the range - if anything I'd expect them to say maybe take your 125 every three days (100 the rest of the time) and retest in six weeks.

What are your pulse, temp and (sorry) bowels like?

I wonder what your t3 levels are.

Sorry you aren't feeling well.

[shaws]

Beware of adjusting medication due only to the TSH result. Your Vitamin B12 is on the low side. We should aim to be towards the upper level. You may have to supplement. Low Vit B12 can cause the tingling, pricking.

There is no scientific reason for adjusting your medication. Even Dr Toft says in his article in Pulse Online, that we may need a very low or even suppressed TSH or the addition of some T3 (you could ask Endo to add some T3).

This is from Dr Lowe and cursor to the date January 2, 2002 to read the whole question/answer. 3 Extracts:-

1.What’s most important to realize is this: The variation in how different patients respond to the same TSH or T3 level makes the reference ranges (formerly called the "ranges of normal") for the T3, TSH, or any other hormone totally without value in finding the dose of thyroid hormone that’s safe and effective for individual patients.[1,p.1217].

2. that researchers have scientifically established the safe and effective dose of thyroid hormone for all human beings. That dose, they presume, is one that keeps the TSH and thyroid hormone levels within their reference ranges. This, however, is a false and scientifically unjustified presumption.

3.Many patients know the presumption is false; they know it’s false because they, like you, become and remain ill when their doctors adjust their thyroid hormone dose according to the TSH level. I know the presumption is false for three reasons: (1) I've studied the research literature which shows that the presumption hasn't been established. (2) I've objectively assessed the tissue metabolic status of patients whose thyroid hormone doses were regulated by TSH levels and found the tissues understimulated. And (3), I've seen hundreds of such patients—formerly kept ill by TSH-adjusted thyroid hormone doses—fully recover their health when my cotreating doctors and I treated them in violation of the guidelines of the conventional endocrinology specialty.

[lucylocks in reply to shaws]

Hi shaws

Many thanks for your reply, as I have just replied to punturedbicycle I should get my T3 result next month at endo appt. but in Dec. last year it was 4.4 range 3.8 - 6.0 and I was on a higher dose of levo.

[lucylocks]

Hi

Thanks for your reply

temp. is around 36.5

pulse varies, anything from 68 to 85 when resting,

bowels on the constipated side but very occasionally the other way (This is about twice a month)

Hoping to get T3 level next month at endo appt. but 3rd Dec. 2013 it was 4.4 range 3.8 - 6.0

and I was taking 125mcg daily then but the month previous I was taking 150mcg but had to reduce to the 125mcg because of severe palpitations and internal shaking.

[puncturedbicycle in reply to lucylocks]

So more on the hypo side of things. It sounds like if anything t4 could be raised a tiny bit and/or a little t3 added in. Did you feel better on 125?

[lucylocks in reply to puncturedbicycle]

Yes I did feel better on 125mcg. the niggling anxiety improved but at the endo appt. I saw the edo's registra and because my THS then was 0.05 she said to reduce to 100mcg. I said I felt better on 125mcg. that's when she said I should take alternative 100/125

[puncturedbicycle in reply to lucylocks]

Yes, I get terrible anxiety even when I reduce my t4, even if I add in extra t3. (I still haven't figured that out.)

If 125 is working for you and your tsh is suppressed but your t3 is in range I can't see the problem. Maybe request the actual consultant next time? (Not that that is any guarantee, but s/he might be a bit more savvy about the tsh if they are good. I saw a useless registrar and requested the consultant and had a better experience next time.)

[lucylocks in reply to puncturedbicycle]

Thankyou, yes I will ask to see the consultant next, in fact I may ring the clinic the week before to ask if he will be available to see as I don't want to be fobbed off when I go to the appt.

The anxiety is awful isn't it, I feel this is the worse of the symptoms.

[Clutter]

Tell your GP the endo will do his nut if your dose is interfered with. GP will either back off or contact the endo and you can coast on for another few weeks.

I'd be inclined to increase meds to 125mcg every day to see if symptoms improved.

[lucylocks in reply to Clutter]

Many thanks Clutter, I did feel better on 125mcg. so will push endo to prescribe this dose

[ianessex]

The day the tsh is finally seen for what it is will be the day thyroid patients actually get better care,, your actual thyroid levels are as stated in above comments,, plus a further reduction would only surely lower them further,,

[lucylocks in reply to ianessex]

Many thanks for your reply, I am going push for the 125mcg.