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Zytiga
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Two questions
I have been on lupron and casodex which worked for a while tried xtandi and did not work had 42 days of radiation now on
Zytiga
for about 3 months.
I have been on lupron and casodex which worked for a while tried xtandi and did not work had 42 days of radiation now on
Zytiga
for about 3 months.
Scootman
in
Advanced Prostate Cancer
3 years ago
To the brains of this forum ,a question about PET/CT PSMA result
PSA readings during this time: 06/18 : 2.44 08/18 : 0.12 1.15ng/DL 12/18: 0.07 1.15ng/DL 3/19 : 0.04 1.15ng/DL 06/19: undetectable 1.15ng/DL 09/19:undetectable 1.15ng/DL 01/20:undetectable 1.15ng/DL last Lucrin shot : April 2018 Stopped
Zytiga
: 06/20 05/20:undetectable 1.15ng/DL 09/20:undetectable
PSA readings during this time: 06/18 : 2.44 08/18 : 0.12 1.15ng/DL 12/18: 0.07 1.15ng/DL 3/19 : 0.04 1.15ng/DL 06/19: undetectable 1.15ng/DL 09/19:undetectable 1.15ng/DL 01/20:undetectable 1.15ng/DL last Lucrin shot : April 2018 Stopped
Zytiga
: 06/20 05/20:undetectable 1.15ng/DL 09/20:undetectable
dorke
in
Advanced Prostate Cancer
3 years ago
Lymparza
He has been on
Zytiga
since Sept. the lowest his psa has come down it to 13.3. The last week he has been aching in different areas. 😩😩. As I have mentioned in the past he is castrate resistant and has the CDK12 mutation. They want to try him on Lymparza not sure the spelling.
He has been on
Zytiga
since Sept. the lowest his psa has come down it to 13.3. The last week he has been aching in different areas. 😩😩. As I have mentioned in the past he is castrate resistant and has the CDK12 mutation. They want to try him on Lymparza not sure the spelling.
Fight11
in
Advanced Prostate Cancer
3 years ago
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After the BCR and the ADT vacation – All the tests results are in – it's curtain time - what comes next – what to do next ?
Zytiga
or another class of second generation ADT that does not act like Lupron and essentially chemically castrate you ?
Zytiga
or another class of second generation ADT that does not act like Lupron and essentially chemically castrate you ?
RonnyBaby
in
Advanced Prostate Cancer
3 years ago
Update after 3rd Lu177
However, the latest F18 PSMA pet scan showed increased number and psma avidity of skeletal mets 😢 We have tried
Zytiga
, Docetaxel, back to
Zytiga
and latest is Lu177. Along with Xgeva and Eligard/Lupron all throughout since diagnosis in 2018. No genetic mutations when blood was tested 2yrs ago.
However, the latest F18 PSMA pet scan showed increased number and psma avidity of skeletal mets 😢 We have tried
Zytiga
, Docetaxel, back to
Zytiga
and latest is Lu177. Along with Xgeva and Eligard/Lupron all throughout since diagnosis in 2018. No genetic mutations when blood was tested 2yrs ago.
dvcarola2
in
Advanced Prostate Cancer
3 years ago
When to do 'advanced' tests?
My husband is still hormone sensitive - MHSPC (we think) and taking ADT plus
Zytiga
. The last PSA had increased from .92 to 1.3 from tests 2 weeks apart. That was a month ago and we now await results of latest bloods this week.
My husband is still hormone sensitive - MHSPC (we think) and taking ADT plus
Zytiga
. The last PSA had increased from .92 to 1.3 from tests 2 weeks apart. That was a month ago and we now await results of latest bloods this week.
Proflac
in
Advanced Prostate Cancer
3 years ago
Gaining weight on ADT
I’ve been on Lupron for about 2 years and
Zytiga
/prednisone for the past year. I’m metastatic, with a few bone and lymph node mets. PSA levels have dropped to no-detect for the past 6 months. Wooooot! But I’ve dropped some weight without trying. I’m about 5’-10” and typically at about 165.
I’ve been on Lupron for about 2 years and
Zytiga
/prednisone for the past year. I’m metastatic, with a few bone and lymph node mets. PSA levels have dropped to no-detect for the past 6 months. Wooooot! But I’ve dropped some weight without trying. I’m about 5’-10” and typically at about 165.
LessPaul
in
Advanced Prostate Cancer
3 years ago
Question
My dad had local prostate cancer and 50 IMRT and lupron for 18 months - then was off everything until 5 years later when Psa creeped up now he has a few bone Mets- when back on lupron and
Zytiga
the psa is low- does that mean he is hormone sensitive still -
My dad had local prostate cancer and 50 IMRT and lupron for 18 months - then was off everything until 5 years later when Psa creeped up now he has a few bone Mets- when back on lupron and
Zytiga
the psa is low- does that mean he is hormone sensitive still -
Chris52981
in
Advanced Prostate Cancer
3 years ago
Rising PSA but low T
After two years on
Zytiga
, my PSA is creeping up (but still under 10), doubling about every 4 weeks. At this exponential growth rate it will be about 5000 in a year. However, Doc unconcerned because he says T is low. Is that correct? What would indicate it is time to switch therapies?
After two years on
Zytiga
, my PSA is creeping up (but still under 10), doubling about every 4 weeks. At this exponential growth rate it will be about 5000 in a year. However, Doc unconcerned because he says T is low. Is that correct? What would indicate it is time to switch therapies?
jersy
in
Advanced Prostate Cancer
3 years ago
PSA rise on Zytiga
On
Zytiga
for about 2 years with undetectable PSA. Two months ago a rise to 0.4, and then 6 weeks later it doubled to 0.8. I assume such a velocity means
Zytiga
is failing. Is that right? Thanks!!!
On
Zytiga
for about 2 years with undetectable PSA. Two months ago a rise to 0.4, and then 6 weeks later it doubled to 0.8. I assume such a velocity means
Zytiga
is failing. Is that right? Thanks!!!
jersy
in
Advanced Prostate Cancer
3 years ago
Zytiga and prednisone holiday.
My Dr has given me a break from the
Zytiga
and prednisone based on excellent results from earlier radiation treatment this year. I am experiencing severe migraines the past few days since I stopped taking 5 days ago. I’m assuming there has to be some side effects and the migraine is all I have.
My Dr has given me a break from the
Zytiga
and prednisone based on excellent results from earlier radiation treatment this year. I am experiencing severe migraines the past few days since I stopped taking 5 days ago. I’m assuming there has to be some side effects and the migraine is all I have.
db1966
in
Advanced Prostate Cancer
3 years ago
Small up tick
He is on
Zytiga
and prednisone. I’m concerned maybe this small up tick is a sign that maybe the med stopped working. Should I have his Doc repeat the psa? If the meds have stopped working he has the cdk12 mutation? Are there other meds he can try or would chemo be next?
He is on
Zytiga
and prednisone. I’m concerned maybe this small up tick is a sign that maybe the med stopped working. Should I have his Doc repeat the psa? If the meds have stopped working he has the cdk12 mutation? Are there other meds he can try or would chemo be next?
Fight11
in
Advanced Prostate Cancer
3 years ago
Thoughts on rising PSA
I'm 72 yrs old on my third hormonal treatment,
Zytiga
. Everything else has stopped working. PSA continues to go up (currently103). I've been on
Zytiga
approx. 6 months. Dr. says the next consideration is Taxotere/chemo. He has concerns about my weight and condition as I do.
I'm 72 yrs old on my third hormonal treatment,
Zytiga
. Everything else has stopped working. PSA continues to go up (currently103). I've been on
Zytiga
approx. 6 months. Dr. says the next consideration is Taxotere/chemo. He has concerns about my weight and condition as I do.
Geter
in
Advanced Prostate Cancer
3 years ago
Advanced and aggressive Pca
He’s taken casodex,
zytiga
and now has done about 8-10 rounds of chemo with dox (spelling) psa steadily climbing into the 800’s. Scans last month showed no advancement of tumors but onc sort of admitted to my mother today that it’s not working and options are low.
He’s taken casodex,
zytiga
and now has done about 8-10 rounds of chemo with dox (spelling) psa steadily climbing into the 800’s. Scans last month showed no advancement of tumors but onc sort of admitted to my mother today that it’s not working and options are low.
Weezer513
in
Advanced Prostate Cancer
3 years ago
From PSA 1000+, and screaming with pain while urinating to Undetectable!
Been on Lupron and
Zytiga
/Prednisone for 2 years, a recent visit at Dana Farber, my doc said - to go on ADT vacation!
Been on Lupron and
Zytiga
/Prednisone for 2 years, a recent visit at Dana Farber, my doc said - to go on ADT vacation!
DarkEnergy
in
Advanced Prostate Cancer
3 years ago
Three weeks on abiaterone and prednisone. Yuck
After three weeks on
Zytiga
and prednisone I feel wiped. Is that normal? Does it get better with time?
After three weeks on
Zytiga
and prednisone I feel wiped. Is that normal? Does it get better with time?
scooby0111
in
Advanced Prostate Cancer
3 years ago
VA Cancer Care
My ten years of fighting prostate cancer includes Prostatectomy,radiation, casodex ,Xtandi ,Lupron, Xgeva ,Lu 177 ,
Zytiga
, as well as unresponsive Chemo,s docetaxel and Jevtana . I have been on
Zytiga
and Prednisone for eight months . My PSA moved from 320 to 516 in thirty days.
My ten years of fighting prostate cancer includes Prostatectomy,radiation, casodex ,Xtandi ,Lupron, Xgeva ,Lu 177 ,
Zytiga
, as well as unresponsive Chemo,s docetaxel and Jevtana . I have been on
Zytiga
and Prednisone for eight months . My PSA moved from 320 to 516 in thirty days.
pinejogave
in
Advanced Prostate Cancer
3 years ago
Remark by Oncologist did not make sense
He stated that Psa may not be a good indicator of my situation and the the
zytiga
I have been on for the last 3 months is probably not working. I ask him how many more options I have left and the discussion turned to men with rising Psa have on average about 18 years give or take.
He stated that Psa may not be a good indicator of my situation and the the
zytiga
I have been on for the last 3 months is probably not working. I ask him how many more options I have left and the discussion turned to men with rising Psa have on average about 18 years give or take.
Scootman
in
Advanced Prostate Cancer
3 years ago
What life extending questions would you ask the top oncologist. If you were me.
I was diagnosed with a gleason 9, 4.5 yrs ago, then a rad prostectomy, salvage rad to follow. 2 yrs of
zytiga
and xtandi followed by investigational trial, harpoon.
I was diagnosed with a gleason 9, 4.5 yrs ago, then a rad prostectomy, salvage rad to follow. 2 yrs of
zytiga
and xtandi followed by investigational trial, harpoon.
Costarica1961
in
Advanced Prostate Cancer
3 years ago
Suggestions on next step of therapy
Started Lupron then, added
Zytiga
/Prednisone in May 2019. Due to also having progressive MS we opted for the
Zytiga
approach as opposed to docetaxel. My existing neuropathy was concerning and I didn't want to possibly add to it with the docataxel treatment. Original PSA of 368, ALP 575.
Started Lupron then, added
Zytiga
/Prednisone in May 2019. Due to also having progressive MS we opted for the
Zytiga
approach as opposed to docetaxel. My existing neuropathy was concerning and I didn't want to possibly add to it with the docataxel treatment. Original PSA of 368, ALP 575.
Kentucky1
in
Advanced Prostate Cancer
3 years ago
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