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after being fast tracked ABD-147 was designed orphan drug for the Treatment of Neuroendocrine Carcinoma (prostate included)
DLL3 is expressed by neuroendocrine cancers, including prostate cancer! They plan to start a phase 1 trial by the end of 2024 (on lung cancer, but it’s worth to keep an eye on it). “ABD-147 is a next-generation precision radiopharmaceutical biologic therapy designed to deliver Actinium-225 (225Ac)
DLL3 is expressed by neuroendocrine cancers, including prostate cancer! They plan to start a phase 1 trial by the end of 2024 (on lung cancer, but it’s worth to keep an eye on it). “ABD-147 is a next-generation precision radiopharmaceutical biologic therapy designed to deliver Actinium-225 (225Ac)
Maxone73
in
Advanced Prostate Cancer
23 days ago
switch from peg interferon to Jakavi due to shortage, anyone doing the same?
Hello friends, I’ve PV jak 2 for 4 years now. Been on peg interferon 45mg weekly for the last year. My bloods have been good(platelets down to 350 from 1100) but my thyroid playing up and I’m on eltroxin for that 100mg a day. I just had a call with my haematologist and MPN specialist in Dublin and
Hello friends, I’ve PV jak 2 for 4 years now. Been on peg interferon 45mg weekly for the last year. My bloods have been good(platelets down to 350 from 1100) but my thyroid playing up and I’m on eltroxin for that 100mg a day. I just had a call with my haematologist and MPN specialist in Dublin and
Deevie1
in
MPN Voice
23 days ago
lung cancer not pc
not sure how to take this: 1.) the cancer spreading in my lungs is an adenocarcinoma but is not from the prostrate but a separate cancer. 2.) the cancer in the prostrate gleason9, and idc has not yet spread beyond the prostrate, per all the scans, etc. I am unsure how to take this. been told it
not sure how to take this: 1.) the cancer spreading in my lungs is an adenocarcinoma but is not from the prostrate but a separate cancer. 2.) the cancer in the prostrate gleason9, and idc has not yet spread beyond the prostrate, per all the scans, etc. I am unsure how to take this. been told it
Cp014
in
Advanced Prostate Cancer
23 days ago
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Breast cancer bra and prosthesis
Hello, We are manufacturer of braest cancer bra, Cotton Prosthesis, silicon prosthesis, hand belts, chest belts, hand globs etc,. All products available which is needed post postactemy... We are available 24/7 and 7 days, All india supply thru courier... Kindly contact on above no. 7509634843 Kamal
Hello, We are manufacturer of braest cancer bra, Cotton Prosthesis, silicon prosthesis, hand belts, chest belts, hand globs etc,. All products available which is needed post postactemy... We are available 24/7 and 7 days, All india supply thru courier... Kindly contact on above no. 7509634843 Kamal
Kamalkumar
in
Breast Cancer India
23 days ago
My Flexible Cystoscopy - and update.
I went for my flexible cystoscopy this morning. I was seen pretty quick and the doctors and nurses very sensative. The cystoscopy took less that 15 minutes and unfortunately they found a start of a tumor. I was watching on a screen and it really did not look much, but I have to be admited
I went for my flexible cystoscopy this morning. I was seen pretty quick and the doctors and nurses very sensative. The cystoscopy took less that 15 minutes and unfortunately they found a start of a tumor. I was watching on a screen and it really did not look much, but I have to be admited
Ern007
in
Lung Conditions Community Forum
23 days ago
Desensitization protocol
Hello ladies, After switching to docetaxel due to a strong reaction to taxol, I had a similar reaction although milder to the second docetaxel infusion. So now my doctor wants me to try nab paclitaxel. I know it’s supposed to be less allergenic but the risk is not 0 even with this one. I have a preexisting
Hello ladies, After switching to docetaxel due to a strong reaction to taxol, I had a similar reaction although milder to the second docetaxel infusion. So now my doctor wants me to try nab paclitaxel. I know it’s supposed to be less allergenic but the risk is not 0 even with this one. I have a preexisting
Lara1
in
My Ovacome
23 days ago
Cancer blood test concepts may be based on flawed science: WSJ, Becker's Hospital Review, 09/03/24
I do not know if this affects any of the CTC or other blood tests in use for PCa, but it is reason to investigate further if you are considering using one in developing a treatment strategy. Another example that the use of highly-touted large-learning models [i](AI)[/i] does not in any way guarantee
I do not know if this affects any of the CTC or other blood tests in use for PCa, but it is reason to investigate further if you are considering using one in developing a treatment strategy. Another example that the use of highly-touted large-learning models [i](AI)[/i] does not in any way guarantee
cujoe
in
Fight Prostate Cancer
24 days ago
A heavy heart at the loss of my dog, Stevie
She was my light. She was my life. She was my time waster. She was my reason for going for a walk and I think she was my reason for living.. My little girl Stevie died on Monday at noon after getting ill on Sunday morning I rushed her to the vet. They kept me waiting for four hours. They took her in
She was my light. She was my life. She was my time waster. She was my reason for going for a walk and I think she was my reason for living.. My little girl Stevie died on Monday at noon after getting ill on Sunday morning I rushed her to the vet. They kept me waiting for four hours. They took her in
Timtam56
in
SHARE Metastatic Breast Cancer
24 days ago
Liquid Biopsy
My mom's onco is suggesting liquid biopsy as she does not have good site for tissue and lately not responding to treatment regimen. Her cancer shed lot of cancer cell leading to very high level of CA125 on other hand. Does anybody have experience with liquid biopsy and have a suggestion for a good lab
My mom's onco is suggesting liquid biopsy as she does not have good site for tissue and lately not responding to treatment regimen. Her cancer shed lot of cancer cell leading to very high level of CA125 on other hand. Does anybody have experience with liquid biopsy and have a suggestion for a good lab
msuspartan
in
My Ovacome
24 days ago
New to this…just saw my PSMA
Howdy all. Let me give you a little back ground. I was having some “back” and stomach issues in June and all of July into August. Blood work looked fine, a mass was seen in CT scan near my rectum and lymph nodes in back were swollen. I work in Europe some and traveled for work. My PSA came back at 166
Howdy all. Let me give you a little back ground. I was having some “back” and stomach issues in June and all of July into August. Blood work looked fine, a mass was seen in CT scan near my rectum and lymph nodes in back were swollen. I work in Europe some and traveled for work. My PSA came back at 166
ChickenWrangler
in
Advanced Prostate Cancer
25 days ago
Female Hormone Blood Tests and Testosterone Gel Question.
I've been weighing up the merits of asking for some testosterone gel on NHS. I didnt want to proceed without knowing my female hormone status so I carried out a Randox health home test last week. I already take HRT in tablet form, my results seem ok. My testosterone is in range but looks low, ditto
I've been weighing up the merits of asking for some testosterone gel on NHS. I didnt want to proceed without knowing my female hormone status so I carried out a Randox health home test last week. I already take HRT in tablet form, my results seem ok. My testosterone is in range but looks low, ditto
Sparklingsunshine
in
Thyroid UK
25 days ago
Mindblowing (and hopefully actionable soon): Innovative In-Vivo Reprogramming to Transform Cancer Therapy
it could work also in the context of cold tumors like prostate cancer! The bad part, they think they will be ready for clinical trials in 2 years. A new immuno-oncology approach is being developed to reprogram tumor cells into dendritic cells directly within the patient, bypassing traditional cell therapy
it could work also in the context of cold tumors like prostate cancer! The bad part, they think they will be ready for clinical trials in 2 years. A new immuno-oncology approach is being developed to reprogram tumor cells into dendritic cells directly within the patient, bypassing traditional cell therapy
Maxone73
in
Advanced Prostate Cancer
26 days ago
Back, neck and shoulder massage
Hello ladies. Im panicking again. I recently got diagnosed with stage 1 low grade ovarian cancer. I had all of my pelvic/par-aortic lymph nodes removed, none of them had cancer cells in them. My oncologist said a massage is fine. But I am worried about the missing lymph nodes. Not from the point
Hello ladies. Im panicking again. I recently got diagnosed with stage 1 low grade ovarian cancer. I had all of my pelvic/par-aortic lymph nodes removed, none of them had cancer cells in them. My oncologist said a massage is fine. But I am worried about the missing lymph nodes. Not from the point
Worrywart2000
in
My Ovacome
26 days ago
ACTOv clinical trial
Hello All We've been asked to share the following information regarding a clinical trial: ACTOv is a clinical trial investigating a new personalised treatment approach to treat ovarian cancer that has relapsed (returned after previously receiving platinum chemotherapy treatment). The new treatment
Hello All We've been asked to share the following information regarding a clinical trial: ACTOv is a clinical trial investigating a new personalised treatment approach to treat ovarian cancer that has relapsed (returned after previously receiving platinum chemotherapy treatment). The new treatment
OvacomeSupport
My Ovacome Team
in
My Ovacome
26 days ago
Aussies will save us all: from Oz, a molecule that can (could) treat resistant prostate cancer
They will need some time still...but... "CDKI-73 is currently being investigated in Phase 2 clinical trials in patients with relapsed and therapy-resistant acute myeloid leukaemia, an aggressive blood cancer." Which means that at least we would not have to wait for a phase 1 to tell us the therapeutic
They will need some time still...but... "CDKI-73 is currently being investigated in Phase 2 clinical trials in patients with relapsed and therapy-resistant acute myeloid leukaemia, an aggressive blood cancer." Which means that at least we would not have to wait for a phase 1 to tell us the therapeutic
Maxone73
in
Advanced Prostate Cancer
26 days ago
Proton or Photon
Hi all, my wife and I are trying to determine the best choice for my prostate cancer. The biopsy/pet scan showed advanced prostate cancer with spreading to the right seminal vessel and involvement of one lymph node. We have had our first consult, locally, with a radiation (x-ray/photon) Dr. who suggested
Hi all, my wife and I are trying to determine the best choice for my prostate cancer. The biopsy/pet scan showed advanced prostate cancer with spreading to the right seminal vessel and involvement of one lymph node. We have had our first consult, locally, with a radiation (x-ray/photon) Dr. who suggested
Garfield-_1234
in
Advanced Prostate Cancer
28 days ago
Bechets support pip
Hi I was wondering if anybody is on pip or had won there win appeal.I have severe problems with my mobility I keep getting flare up in my legs and feet they swell up and cause Me inflammation and I find it difficult to do anything as they hurt. And I cannot bare pain or do anything everything is a struggle
Hi I was wondering if anybody is on pip or had won there win appeal.I have severe problems with my mobility I keep getting flare up in my legs and feet they swell up and cause Me inflammation and I find it difficult to do anything as they hurt. And I cannot bare pain or do anything everything is a struggle
Tibz
in
Behçet's UK
5 months ago
Constant uptightness and lightheadedness
Since i was like 9 i always felt very uptight and inhibited. Iam 23 now. This doesnt affect my athletic capabilities,but much more so my mental state. This goes to the point where i now can't ever think clearly. Iam consntantly tired and never well-rested after waking up.I dont feel myself as much
Since i was like 9 i always felt very uptight and inhibited. Iam 23 now. This doesnt affect my athletic capabilities,but much more so my mental state. This goes to the point where i now can't ever think clearly. Iam consntantly tired and never well-rested after waking up.I dont feel myself as much
harryford01
in
Men's Health Forum
29 days ago
Is Curcumin Another "Double-Edged Sword" In The Fight Against Prostate Cancer?" Still spinning my head trying to figure it out.
Many in-vitro and in-vivo studies point to antiproliferative, antimetastatic, anti-inflammatory, anti-invasive, etc. properties that Curcumin have against prostate cancer cells. But the compound is also regarded as a significant booster of Testosterone, which is a major driver of androgen-sensitive
Many in-vitro and in-vivo studies point to antiproliferative, antimetastatic, anti-inflammatory, anti-invasive, etc. properties that Curcumin have against prostate cancer cells. But the compound is also regarded as a significant booster of Testosterone, which is a major driver of androgen-sensitive
back2health
in
Advanced Prostate Cancer
29 days ago
Re running following illness
Just completed week 5 run 3. I’d been dreading stepping up to 20 minutes running, however, not as bad as I had been expecting. All in the head!!! Starting again after being diagnosed with rectal cancer and undergoing a colostomy operation in May. I was feeling pretty down for a while, thought useful
Just completed week 5 run 3. I’d been dreading stepping up to 20 minutes running, however, not as bad as I had been expecting. All in the head!!! Starting again after being diagnosed with rectal cancer and undergoing a colostomy operation in May. I was feeling pretty down for a while, thought useful
Silverslowcoach1961
in
Couch to 5K
30 days ago
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