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Results:Ibuprofen was significantly more effective against human prostate cancer cells in vitro than the other tested nonprescription NSAID
"MTT analysis indicated that clinically relevant concentrations of ibuprofen significantly reduced the survival of LNCaP human prostate tumor cells. TUNEL analysis demonstrated that this was due in part to a significant number of LNCaP cells undergoing apoptosis. Ibuprofen also induced the same amount
"MTT analysis indicated that clinically relevant concentrations of ibuprofen significantly reduced the survival of LNCaP human prostate tumor cells. TUNEL analysis demonstrated that this was due in part to a significant number of LNCaP cells undergoing apoptosis. Ibuprofen also induced the same amount
George71
in
Advanced Prostate Cancer
4 years ago
NHS care is falling apart
This is about my sister who has been in hospital for 3 nights. She was admitted straight from A&E with pain and her bloods flagged up major inflammation. Diagnosed with diverticulitis ( never had this before)and is on IV antibiotics . told by doctor what she can and cannot eat. Menu is given out to choose
This is about my sister who has been in hospital for 3 nights. She was admitted straight from A&E with pain and her bloods flagged up major inflammation. Diagnosed with diverticulitis ( never had this before)and is on IV antibiotics . told by doctor what she can and cannot eat. Menu is given out to choose
Hidden
in
NRAS
4 years ago
New here so be gentle with me!
Hi just joined as have been diagnosed with Lupus in last few weeks, after 2 years of back and forth to gp. Eventually spoke to a consultant (couldn't see him because of covid) and he was no help at all, has made another appointment for January. In the meantime my symptoms seem to have escalated somewhat
Hi just joined as have been diagnosed with Lupus in last few weeks, after 2 years of back and forth to gp. Eventually spoke to a consultant (couldn't see him because of covid) and he was no help at all, has made another appointment for January. In the meantime my symptoms seem to have escalated somewhat
welshmaiden59
in
LUPUS UK
4 years ago
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New to Fibro..
After hard long 3months GP has diagnosed me with fibromyalgia. This invisible condition for others- that's the hardest part! Been suffering from burning pain in Thighs, legs bottom of feet, lower back and sometimes in palms. Along this extreme fatigue which lead to anxiety/panic attacks, insomnia and
After hard long 3months GP has diagnosed me with fibromyalgia. This invisible condition for others- that's the hardest part! Been suffering from burning pain in Thighs, legs bottom of feet, lower back and sometimes in palms. Along this extreme fatigue which lead to anxiety/panic attacks, insomnia and
Alizah
in
Fibromyalgia Action UK
4 years ago
Continuous pain
Waiting for laparoscopy and changing to a combined pill. I'm in absolute agony continuously. I'm on gabapentin and mefenamic acid and paracetamol. I've been using a tens machine and hot water bottle. If any one has any suggestions to relieve pain I am really open at this point I'm just so fed up
Waiting for laparoscopy and changing to a combined pill. I'm in absolute agony continuously. I'm on gabapentin and mefenamic acid and paracetamol. I've been using a tens machine and hot water bottle. If any one has any suggestions to relieve pain I am really open at this point I'm just so fed up
bonnieclyde97
in
Endometriosis UK
4 years ago
Belly button pain and bleeding post Laparoscopy
Hi guys, I’m one day post op and now home on regular pain relief, switching between paracetamol or codine and ibprufen or menafanmic acid. My incision site through my belly button is causing so much pain and discomfort even with regular pain relief and have had to change the dressing twice due to more
Hi guys, I’m one day post op and now home on regular pain relief, switching between paracetamol or codine and ibprufen or menafanmic acid. My incision site through my belly button is causing so much pain and discomfort even with regular pain relief and have had to change the dressing twice due to more
Coolcatandkittens
in
Endometriosis UK
4 years ago
Recent diagnosis
Hi everyone! I have only recently been diagnosed with endometriosis and am still new to the condition. I started having painful periods at the age of 11 and was always in and out of hospital due to abdominal pains. 10 years and 3 laparoscopies later at the age of 21, I was finally diagnosed with endometriosis
Hi everyone! I have only recently been diagnosed with endometriosis and am still new to the condition. I started having painful periods at the age of 11 and was always in and out of hospital due to abdominal pains. 10 years and 3 laparoscopies later at the age of 21, I was finally diagnosed with endometriosis
Katiewright99x
in
Endometriosis UK
4 years ago
Sorry if
Hi all , I am 33 was diagnosed with Endometriosis and Dyspareunia 4 years ago by laparoscopy diathermy and insertion of Marina, to which i was I had some relief for roughly 6 months then late 2017 I was given Leuprorelin (Prostap, Lutrate) injections for 3 months these helped my cramps but the headache
Hi all , I am 33 was diagnosed with Endometriosis and Dyspareunia 4 years ago by laparoscopy diathermy and insertion of Marina, to which i was I had some relief for roughly 6 months then late 2017 I was given Leuprorelin (Prostap, Lutrate) injections for 3 months these helped my cramps but the headache
kitten4687
in
The Endometriosis Foundation
4 years ago
Tackling knee pain without injections or surgery
As a child I suffered incredible knee pain for a few years aged around 14. Doctors said growing pains, and my Dad used to rub my legs with wintergreen, sort of horse lineament I think. I played sport until I was 23 and was active all my life but aged around 70 I began to suffer very painful knees. I
As a child I suffered incredible knee pain for a few years aged around 14. Doctors said growing pains, and my Dad used to rub my legs with wintergreen, sort of horse lineament I think. I played sport until I was 23 and was active all my life but aged around 70 I began to suffer very painful knees. I
hc75
in
Osteoarthritis Action
4 years ago
Hyterscopy and miruena coil
Hello - like to know your experience of having a hyesterscopy - been told a few paracetamol all that is needed and also fit a miruena coil. Apparently I have Adenomyosis (as well as stage iv endo which I knew about) but wants to exclude womb cancer. Is this true it doesn’t hurt? Also any experiences
Hello - like to know your experience of having a hyesterscopy - been told a few paracetamol all that is needed and also fit a miruena coil. Apparently I have Adenomyosis (as well as stage iv endo which I knew about) but wants to exclude womb cancer. Is this true it doesn’t hurt? Also any experiences
Goodgrief20
in
Women's Health
4 years ago
Pain so bad. Is A&E worth it?
Had to come home from work due to debilitating endo flare up pain. I am now in bed. I take my mefenamic acid three times a day but it does NOTHING for me when I have a flare up. Also had peppermint tea and have a scolding hot water bottle and wheat bag. Has anyone been to A&E in the UK with endo pain
Had to come home from work due to debilitating endo flare up pain. I am now in bed. I take my mefenamic acid three times a day but it does NOTHING for me when I have a flare up. Also had peppermint tea and have a scolding hot water bottle and wheat bag. Has anyone been to A&E in the UK with endo pain
EndoEffect
in
Endometriosis UK
4 years ago
Another query?
Just a thought. Yet another one. Can anyone out there help, I would be really grateful. After all these years still constantly looking for answers to my pain. Along with fibro, underactive thyroid, kidney disease and irritable bowel, plus all the other extras we get, has anyone experienced interstitial
Just a thought. Yet another one. Can anyone out there help, I would be really grateful. After all these years still constantly looking for answers to my pain. Along with fibro, underactive thyroid, kidney disease and irritable bowel, plus all the other extras we get, has anyone experienced interstitial
ShelWhitt
in
Fibromyalgia Action UK
4 years ago
GCA - Hit my first problem after reducing from 30mg to 25mg prednisolone. Advice please. Thank you
I have GCA diagnosed in May this year when I started on 60mg prednisolone. At first I was told to reduce by 10mg every 2weeks until I get down to 20mg and then 2.5mg every 2 weeks until I reach 10mg.but that was changed to a drop of 5mg every 2 weeks as I had symptoms on the first reduction. Actually
I have GCA diagnosed in May this year when I started on 60mg prednisolone. At first I was told to reduce by 10mg every 2weeks until I get down to 20mg and then 2.5mg every 2 weeks until I reach 10mg.but that was changed to a drop of 5mg every 2 weeks as I had symptoms on the first reduction. Actually
HappyDiamonds
in
PMRGCAuk
4 years ago
Paracetamol causes diarrhoea?!
Hi everyone, I have had IBS for 20 years and am fairly keyed up about it. I find that naturally I don’t react well to anti-inflammatory pain relief (such as ibuprofen) when unwell with other things, but I can’t seem to tolerate paracetamol either. It always triggers watery diarrhoea. I seem to be the
Hi everyone, I have had IBS for 20 years and am fairly keyed up about it. I find that naturally I don’t react well to anti-inflammatory pain relief (such as ibuprofen) when unwell with other things, but I can’t seem to tolerate paracetamol either. It always triggers watery diarrhoea. I seem to be the
IBSLife
in
IBS Network
4 years ago
Taking NSAIDs like Ibruprofen with other drugs
I've injured my hip and wanted to take some anti-inflammatories such as ibruprofen. I vaguely rememberred I was told not to take them at one poiints but thought it was because I was on betablockers. But amiadarone being such a 'fierce' drug I thought I had better double check. Anyway, I contacted my
I've injured my hip and wanted to take some anti-inflammatories such as ibruprofen. I vaguely rememberred I was told not to take them at one poiints but thought it was because I was on betablockers. But amiadarone being such a 'fierce' drug I thought I had better double check. Anyway, I contacted my
Jajarunner
in
AF Association
4 years ago
Spasms I. Stomach and back pain
Dies anyone else have spasms in their stomach just above their naval and does it go round round their waist At the back. Tried Colpermin, tried paracetamol. Bloating as well.
Dies anyone else have spasms in their stomach just above their naval and does it go round round their waist At the back. Tried Colpermin, tried paracetamol. Bloating as well.
Hidden
in
IBS Network
4 years ago
What are your symptoms before B12 is due.?Getting daily headaches.
Hi all, I haven't posted on here for some time. I have been having b12 injections every 12 weeks for about a year and a half now, and have noticed that 2 -3 weeks before my injection is due I start to feel lethargic and out of sorts. I have tried to get injections sooner than the 12 week mark but my
Hi all, I haven't posted on here for some time. I have been having b12 injections every 12 weeks for about a year and a half now, and have noticed that 2 -3 weeks before my injection is due I start to feel lethargic and out of sorts. I have tried to get injections sooner than the 12 week mark but my
Aly2
in
Pernicious Anaemia Society
4 years ago
Joint pain/Bone pain with MF
Recently diagnosed with post ET MF, I have started to get aching in my knees and wrists/hands. I will be able to ask my consultant about it next week but I wondered if this is common with MF or possibly to do with Ruxolitinib. I'm not clear on what bone pain would feel like. It seems to happen more
Recently diagnosed with post ET MF, I have started to get aching in my knees and wrists/hands. I will be able to ask my consultant about it next week but I wondered if this is common with MF or possibly to do with Ruxolitinib. I'm not clear on what bone pain would feel like. It seems to happen more
Otterfield
in
MPN Voice
4 years ago
The Most Common Pain Relief Drug in The World Induces Risky Behaviour, Study Suggests - Tylenol, Panadolc acetaminophen.
The Most Common Pain Relief Drug in The World Induces Risky Behaviour, Study Suggests - Tylenol, Panadolc acetaminophen. https://www.sciencealert.com/the-most-common-pain-relief-drug-in-the-world-induces-risky-behaviour-study-finds
The Most Common Pain Relief Drug in The World Induces Risky Behaviour, Study Suggests - Tylenol, Panadolc acetaminophen. https://www.sciencealert.com/the-most-common-pain-relief-drug-in-the-world-induces-risky-behaviour-study-finds
aspergerian
in
Cure Parkinson's
4 years ago
Newly diagnosed as B12 deficient after suffering symptoms for at least 30+ years & possibly since childhood!
***Warning - Long post alert! I really appreciate anybody who makes it to the end & doubly appreciate anybody who replies! ;-) I have just been diagnosed as being B12 deficient & also Vit D deficient. I was told that my B12 was 76 & then 89 two weeks later & that a reading of 130 would be considered
***Warning - Long post alert! I really appreciate anybody who makes it to the end & doubly appreciate anybody who replies! ;-) I have just been diagnosed as being B12 deficient & also Vit D deficient. I was told that my B12 was 76 & then 89 two weeks later & that a reading of 130 would be considered
CupCake5
in
Pernicious Anaemia Society
4 years ago
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