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Meta prostate linked to high fatb
https://www.cancer.gov/news-events/cancer-currents-blog/2018/high-fat-diet-prostate-
metastasis
#:~:text=A%20new%20study%20in%20mice,and%20spread%20of%20prostate%20cancer.Interesting stuff although like alot of the studies inconclusive which type of fat causes the issue in mice
https://www.cancer.gov/news-events/cancer-currents-blog/2018/high-fat-diet-prostate-
metastasis
#:~:text=A%20new%20study%20in%20mice,and%20spread%20of%20prostate%20cancer.Interesting stuff although like alot of the studies inconclusive which type of fat causes the issue in mice
Beesnbonsai
in
Advanced Prostate Cancer
1 month ago
cheating metastatic cells to kill them (pre clinical)
https://www.fredhutch.org/en/news/center-news/2024/01/immune-cells-prevent-
metastasis
-numbers-game-metastatic-cancer-t-cells.html
https://www.fredhutch.org/en/news/center-news/2024/01/immune-cells-prevent-
metastasis
-numbers-game-metastatic-cancer-t-cells.html
Maxone73
in
Advanced Prostate Cancer
4 months ago
EMBARK Trial: Combination-therapy is better.
Lupron
monotherapy had the greatest risk of developing
metastasis
after 5 years (a 28.6 %), compared to a 20.0% risk for
Enzalutamide
monotherapy. The
combination of Enzalutamide + Lupron
had the lowest risk (12.7%). p < 0.001 (N=1068).
Lupron
monotherapy had the greatest risk of developing
metastasis
after 5 years (a 28.6 %), compared to a 20.0% risk for
Enzalutamide
monotherapy. The
combination of Enzalutamide + Lupron
had the lowest risk (12.7%). p < 0.001 (N=1068).
janebob99
in
Prostate Cancer Network
6 days ago
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Brain metastasis on Ovarian Cancer
The main reason I wanted to write here is that her oncology team monitored a brain
metastasis
in June '2023. After that, she underwent a circle of chemo and radiotherapy. Two months later, her scans showed that the
metastasis
had almost halved in size.
The main reason I wanted to write here is that her oncology team monitored a brain
metastasis
in June '2023. After that, she underwent a circle of chemo and radiotherapy. Two months later, her scans showed that the
metastasis
had almost halved in size.
selosh16
in
My Ovacome
5 months ago
Promising metastasis prevention break-through
https://news.stanford.edu/2023/12/20/breast-cancer-
metastasis
-off-switch-revealed/ It turns out that both breast and prostate cancers are cold tumors so could help prostate cancer survival too.
https://news.stanford.edu/2023/12/20/breast-cancer-
metastasis
-off-switch-revealed/ It turns out that both breast and prostate cancers are cold tumors so could help prostate cancer survival too.
climb4blue
in
Prostate Cancer Network
4 months ago
Bisphosphonate
I forgot to mention I have bone
metastasis
and I live in the US. Thank you.
I forgot to mention I have bone
metastasis
and I live in the US. Thank you.
JEE123
in
SHARE Metastatic Breast Cancer
6 months ago
Another bone metastasis pathway discovered
"Altogether, these findings identify Malat1 as a lncRNA that protects against osteoporosis and bone
metastasis
." Malat1 protects us against Tead 3 protein...wasn't everything easier when we simply had Superman protecting us from The Penguin...no, wait...
"Altogether, these findings identify Malat1 as a lncRNA that protects against osteoporosis and bone
metastasis
." Malat1 protects us against Tead 3 protein...wasn't everything easier when we simply had Superman protecting us from The Penguin...no, wait...
Maxone73
in
Advanced Prostate Cancer
1 month ago
64Cu-SAR-bisPSMA Is Safe and Highly Effective in Detecting Tumours in Prostate Cancer Patients: results from COBRA trial
This could mean being way more precise in finding micro
metastasis
and in guided surgery!
This could mean being way more precise in finding micro
metastasis
and in guided surgery!
Maxone73
in
Advanced Prostate Cancer
2 months ago
Study on creatine and mCRPC: right on time!
And being done on metastatic patients, we should get some reliable info about creatine and bone
metastasis
.
And being done on metastatic patients, we should get some reliable info about creatine and bone
metastasis
.
Maxone73
in
Advanced Prostate Cancer
9 days ago
In vivo and on breast cancer bone metastasis but....100% with repurposed drugs
Ok they are not saying which drugs and I can quite understand them, but results seem very promising: https://medicalxpress.com/news/2024-04-drugs-hinder-bone-
metastasis
-breast.html "Based on their findings, the researchers predict that in the future, the treatment can be applied to human patients with
Ok they are not saying which drugs and I can quite understand them, but results seem very promising: https://medicalxpress.com/news/2024-04-drugs-hinder-bone-
metastasis
-breast.html "Based on their findings, the researchers predict that in the future, the treatment can be applied to human patients with
Maxone73
in
Fight Prostate Cancer
25 days ago
Some good advancements today too: Advances in Engineered Macrophages - A New Frontier in Cancer Immunotherapy
"These cells act synergistically in tumour progression, invasion,
metastasis
, and response to immunotherapies.
"These cells act synergistically in tumour progression, invasion,
metastasis
, and response to immunotherapies.
Maxone73
in
Advanced Prostate Cancer
27 days ago
How about eating a healthy snack that might help fight PCa. Lotus seeds (Nelumbo nucifera) also known as makhana contain Neferine, see below
More than 90% of cancer-related deaths develop after
metastasis
, and CSCs are considered to be largely responsible for the cell migration and invasion.
More than 90% of cancer-related deaths develop after
metastasis
, and CSCs are considered to be largely responsible for the cell migration and invasion.
Graham49
in
Advanced Prostate Cancer
21 days ago
Follow up to "My trajectory after a 'vacation' and a new metastasis," and a new question
The second
metastasis
is in a lymph node in my chest and close to where the resolved first
metastasis
was in a lung.
The second
metastasis
is in a lymph node in my chest and close to where the resolved first
metastasis
was in a lung.
Istomin
in
Advanced Prostate Cancer
4 months ago
18F-flotufolastat PET alters treatment approach for nearly 90% of patients with recurrent prostate cancer
"18F-flotufolastat is approved by the FDA for use in patients with suspected prostate cancer
metastasis
who are potentially curable by definitive surgery or radiation, and patients with suspected prostate cancer recurrence based on elevated PSA levels."
"18F-flotufolastat is approved by the FDA for use in patients with suspected prostate cancer
metastasis
who are potentially curable by definitive surgery or radiation, and patients with suspected prostate cancer recurrence based on elevated PSA levels."
Maxone73
in
Advanced Prostate Cancer
3 months ago
HoLEP for BPH followed by SBRT several months later for 4+3 = 7 PCa. Is it preferable to do the HoLEP before the SBRT?
PSMA-Pet no
metastasis
. PSA 8.8. Decipher 0.51. PSA density 0.11. Having HoLEP in May 2024 then SBRT several months later.
PSMA-Pet no
metastasis
. PSA 8.8. Decipher 0.51. PSA density 0.11. Having HoLEP in May 2024 then SBRT several months later.
Bourbon2024
in
Prostate Cancer Network
3 months ago
Super CAR-T therapies
This seems promising in keeping PCa a controllable disease https://www.fredhutch.org/en/news/center-news/2024/01/immune-cells-prevent-
metastasis
-numbers-game-metastatic-cancer-t-cells.html
This seems promising in keeping PCa a controllable disease https://www.fredhutch.org/en/news/center-news/2024/01/immune-cells-prevent-
metastasis
-numbers-game-metastatic-cancer-t-cells.html
Scout4answers
in
Fight Prostate Cancer
4 months ago
Vacation from Lupron/Zytiga - Temporary or Permanent!
CT/Bone scan did not show any definite
metastasis
. PSMA PET showed "possible"
metastasis
in 4 spots around ribs. "Indeterminate" and "suspicious" was the radiologist's wording. Treated aggressively due to possible Stage 4. Had 25 rounds radiation of prostate for primary tumor last year.
CT/Bone scan did not show any definite
metastasis
. PSMA PET showed "possible"
metastasis
in 4 spots around ribs. "Indeterminate" and "suspicious" was the radiologist's wording. Treated aggressively due to possible Stage 4. Had 25 rounds radiation of prostate for primary tumor last year.
groth12345
in
Advanced Prostate Cancer
6 months ago
225 AC PSMA J591 is active in mCRPC with difficult metastasis
Interestinggly, it seems to work better than Pluvicto for
metastasis
..."it showed median declines of -52%, -40%, -23% in visceral, bone, and nodal lesions, respectively." https://www.urologytimes.com/view/225ac-psma-j591-active-in-mcrpc-with-difficult-to-treat-metastatic-sites
Interestinggly, it seems to work better than Pluvicto for
metastasis
..."it showed median declines of -52%, -40%, -23% in visceral, bone, and nodal lesions, respectively." https://www.urologytimes.com/view/225ac-psma-j591-active-in-mcrpc-with-difficult-to-treat-metastatic-sites
Maxone73
in
Advanced Prostate Cancer
5 months ago
Stage 4. IMRT + HDR Brachytherapy
I have Stage 4 (
metastasis
in L2). Currently on ADT. I have chosen IMRT followed by HDR Brachytherapy. I'm starting IMRT in January 2024. What was you experience with this combination? Did it work? Any side effects? Thank you for your responses.
I have Stage 4 (
metastasis
in L2). Currently on ADT. I have chosen IMRT followed by HDR Brachytherapy. I'm starting IMRT in January 2024. What was you experience with this combination? Did it work? Any side effects? Thank you for your responses.
FightCancer101
in
Advanced Prostate Cancer
4 months ago
Metastatic PC that produces no or low PSA
Hi All, Looking to connect with people with metastatic PC that produces no or low PSA I am 44 and was diagnosed with PC with a bone
metastasis
grade 4+5. My PSA at time of diagnosis was 0.54. I’m undergoing PEACE 1 protocol treatment. Finish RT and Doxetaxel still on Zytiga.
Hi All, Looking to connect with people with metastatic PC that produces no or low PSA I am 44 and was diagnosed with PC with a bone
metastasis
grade 4+5. My PSA at time of diagnosis was 0.54. I’m undergoing PEACE 1 protocol treatment. Finish RT and Doxetaxel still on Zytiga.
Jumpingbellybeans
in
Advanced Prostate Cancer
23 days ago
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