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New Approach to Resistance
A male neurobiologist, with metastatic breast cancer who studies genetics, developed a new idea to deal with treatment resistance based on the same way Farmers protect their fields from pests. Farmers rotate the pesticide chemicals they use on their fields so that they are never chronically spraying
A male neurobiologist, with metastatic breast cancer who studies genetics, developed a new idea to deal with treatment resistance based on the same way Farmers protect their fields from pests. Farmers rotate the pesticide chemicals they use on their fields so that they are never chronically spraying
Best521
in
SHARE Metastatic Breast Cancer
1 month ago
metastic Breast cancer in chest
Hi I’m pretty new to this site, but love reading the positive posts that give me so much confidence! I’ve had breast cancer three times, the first time I was 37 in 1998 the second 54 2016 and again this year diagnosed under my reconstruction and inoperable! March 2024! I’m on Ibrance and Letrozole since
Hi I’m pretty new to this site, but love reading the positive posts that give me so much confidence! I’ve had breast cancer three times, the first time I was 37 in 1998 the second 54 2016 and again this year diagnosed under my reconstruction and inoperable! March 2024! I’m on Ibrance and Letrozole since
Teddypeppalola
in
SHARE Metastatic Breast Cancer
1 month ago
Bone metastasis drug looks good: phase 2 trial of PT-112 gave good results
"Further, PT-112 harbors a property known as osteotropism, or the propensity of the drug to reach its highest concentrations in certain areas of the bone, making it a candidate for treatment of patients with cancers that originate in, or metastasize to, the bone." https://www.biospace.com/article/releases
"Further, PT-112 harbors a property known as osteotropism, or the propensity of the drug to reach its highest concentrations in certain areas of the bone, making it a candidate for treatment of patients with cancers that originate in, or metastasize to, the bone." https://www.biospace.com/article/releases
Maxone73
in
Advanced Prostate Cancer
5 months ago
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Anyone had an increase in bone/joint pain after being on Ibrance and Letrozole for a few years?
I was diagnosed Metastatic BC with a lot of bone mets back in June 2022. The Letrozole and Ibrance eliminated the visible bone mets and pain was better. Last scans still show no progression and those were just a month ago or so. The last few weeks I've had terrible pain in my knees, left shin, and
I was diagnosed Metastatic BC with a lot of bone mets back in June 2022. The Letrozole and Ibrance eliminated the visible bone mets and pain was better. Last scans still show no progression and those were just a month ago or so. The last few weeks I've had terrible pain in my knees, left shin, and
lovnmycat
in
SHARE Metastatic Breast Cancer
1 month ago
palbociclib and letrozole
hi, taking palbo and letrozole for last 6 months and few days back gone for pet scan and scan response was good , many places were reduced and not much metabolic activity. So same medicines prescribed, but now suddenly in both legs nerves are paining like shooting pain heavily, will palbociclib or
hi, taking palbo and letrozole for last 6 months and few days back gone for pet scan and scan response was good , many places were reduced and not much metabolic activity. So same medicines prescribed, but now suddenly in both legs nerves are paining like shooting pain heavily, will palbociclib or
Wickey20
in
SHARE Metastatic Breast Cancer
1 month ago
Good news
I haven't written for a while , just getting on with life! But last week's news is worth reporting.The mammary lymph node they had been monitoring is now too small to report measurements. It was 9 mm last time and has further reduced. My cancer markers are better than two and a half years ago. 15-3 is
I haven't written for a while , just getting on with life! But last week's news is worth reporting.The mammary lymph node they had been monitoring is now too small to report measurements. It was 9 mm last time and has further reduced. My cancer markers are better than two and a half years ago. 15-3 is
Beryl71
in
SHARE Metastatic Breast Cancer
1 month ago
Enzalutamide approved for patients with high risk of metastasis
https://www.onclive.com/view/fda-approves-enzalutamide-for-nmcspc-with-high-risk-biochemical-recurrence
https://www.onclive.com/view/fda-approves-enzalutamide-for-nmcspc-with-high-risk-biochemical-recurrence
Maxone73
in
Advanced Prostate Cancer
9 months ago
Caffeic acid phenethyl ester (CAPE) is an ingredient in bee propolis. See below for invitro and mice evidence for inhibition AR-V7 by CAPE
AR-V7 assists the tumor growth, cancer
metastasis
, cancer stemness, and the evolvement of therapy-resistant prostate cancer (PCa). We discovered that caffeic acid phenethyl ester (CAPE) can repress the expression and downstream signaling of AR-V7 in PCa cells.
AR-V7 assists the tumor growth, cancer
metastasis
, cancer stemness, and the evolvement of therapy-resistant prostate cancer (PCa). We discovered that caffeic acid phenethyl ester (CAPE) can repress the expression and downstream signaling of AR-V7 in PCa cells.
Graham49
in
Advanced Prostate Cancer
5 months ago
State 3 Breast Cancer
I discovered a lump in my breast early in April. Was sent for an ultrasound which was very suspicious. Biopsy revealed cancer. Oncololgist confirmed stage 3 metastic breast cancer. She put me on Anastrozole and when final tests came in started me on Ibrance 100. After two weeks my wbc was very low
I discovered a lump in my breast early in April. Was sent for an ultrasound which was very suspicious. Biopsy revealed cancer. Oncololgist confirmed stage 3 metastic breast cancer. She put me on Anastrozole and when final tests came in started me on Ibrance 100. After two weeks my wbc was very low
catfreddie
in
SHARE Metastatic Breast Cancer
2 months ago
Has anyone had breast cancer Mets in para aortic lymph nodes?
after a solitary bone met which has been managed for a few years, I now have breast cancer Mets in my para aortic lymph nodes. I’m on Fulvestrant.
after a solitary bone met which has been managed for a few years, I now have breast cancer Mets in my para aortic lymph nodes. I’m on Fulvestrant.
Thredbo2
in
SHARE Metastatic Breast Cancer
2 months ago
Has anyone had breast cancer Mets in para aortic lymph nodes?
after a solitary bone met which has been managed for a few years, I now have breast cancer Mets in my para aortic lymph nodes. I’m on Fulvestrant.
after a solitary bone met which has been managed for a few years, I now have breast cancer Mets in my para aortic lymph nodes. I’m on Fulvestrant.
Thredbo2
in
SHARE Metastatic Breast Cancer
2 months ago
Xeloda neck pain
On first week xeloda and I get severe neck and face pain once a day..I take a klonpin and tylenol and relieved in half hour..I don't know if anyone else has it.ROX
On first week xeloda and I get severe neck and face pain once a day..I take a klonpin and tylenol and relieved in half hour..I don't know if anyone else has it.ROX
Mcangel11
in
SHARE Metastatic Breast Cancer
2 months ago
Shirley
I MBC that had spread to bones now found two small spots on lungs. I was taking ansezole for estrogen blocker and venezico .I am ER statuses positive , HER2 negative. They say I have mutation on my cancer an wants me take a treatment PIQKAY and Fulvestrant. I am very nervous taking these. ANYONE
I MBC that had spread to bones now found two small spots on lungs. I was taking ansezole for estrogen blocker and venezico .I am ER statuses positive , HER2 negative. They say I have mutation on my cancer an wants me take a treatment PIQKAY and Fulvestrant. I am very nervous taking these. ANYONE
Moonfry
in
SHARE Metastatic Breast Cancer
2 months ago
Advise for a new diagnosis
Dear community, I wanted to post a message to this forum to ask for advice for my mum who has recently been diagnosed with metastatic breast cancer. Her biopsy is still being tested to determine the exact subtype. Doctors could not see anything un the breast and took a biopsy was taken from one of
Dear community, I wanted to post a message to this forum to ask for advice for my mum who has recently been diagnosed with metastatic breast cancer. Her biopsy is still being tested to determine the exact subtype. Doctors could not see anything un the breast and took a biopsy was taken from one of
Blossom751
in
SHARE Metastatic Breast Cancer
2 months ago
Stop Ibrance?
My HB and Platelets have been bad for a while. Mainly because I haven' eaten anything. I am now eating again and feel much better (I had other reasons), but she has ordered me back for new blood tests and wants me to change to Xeloda. I want a chance to get my appetite back up and eating normally before
My HB and Platelets have been bad for a while. Mainly because I haven' eaten anything. I am now eating again and feel much better (I had other reasons), but she has ordered me back for new blood tests and wants me to change to Xeloda. I want a chance to get my appetite back up and eating normally before
SwedishSissi
in
SHARE Metastatic Breast Cancer
2 months ago
Ready, Set, GO!! LOL
Hi all of my beautiful warrior friends!!! I would like to know what you all have had as far as treatment. I am really most interested in people like me, who have had NO mutations. I am ER+, HER2 LOW I am about to start on Enhertu, but my doctor is hedging to the possibility that I am running out
Hi all of my beautiful warrior friends!!! I would like to know what you all have had as far as treatment. I am really most interested in people like me, who have had NO mutations. I am ER+, HER2 LOW I am about to start on Enhertu, but my doctor is hedging to the possibility that I am running out
CTGirl1962
in
SHARE Metastatic Breast Cancer
2 months ago
Enhertu
Good morning. Has anyone taken Enhertu for breast cancer? What are your pros/cons? Little back story: dx stage 4 metastatic breast cancer, ER/PR +, HERS2 -, but I am considered HERS2 low w/ a count of 1, in April 2022, I was 44 at the time. Left breast, lymph node in left armpit, multiple spots in my
Good morning. Has anyone taken Enhertu for breast cancer? What are your pros/cons? Little back story: dx stage 4 metastatic breast cancer, ER/PR +, HERS2 -, but I am considered HERS2 low w/ a count of 1, in April 2022, I was 44 at the time. Left breast, lymph node in left armpit, multiple spots in my
Felicia1228
in
SHARE Metastatic Breast Cancer
2 months ago
Metastatic Breast cancer
2018. diagnosed with breast cancer-stage one,left breast.Had chemo,surgery and 11 lymph nodes removed,and 2 months radiotherapy. 6 years later (3 months ago)metastatic breast cancer appeared as left side of lung nodule 12 mm,an early stage.Had a surgery.Upper lung lobe,and lymph nodes removed.Did Pet-scan
2018. diagnosed with breast cancer-stage one,left breast.Had chemo,surgery and 11 lymph nodes removed,and 2 months radiotherapy. 6 years later (3 months ago)metastatic breast cancer appeared as left side of lung nodule 12 mm,an early stage.Had a surgery.Upper lung lobe,and lymph nodes removed.Did Pet-scan
Kim452
in
SHARE Metastatic Breast Cancer
2 months ago
What is Your Opinion on Docetaxel Added to Doublet Therapy for Early Oligorecurrent Metaststic M1a Prostate Cancer?
At psa of 0.16 , a PSMA scan showed three sub centimeter retro caval nodes lit up for
metastasis
. His dzx was early metastatic disease. He went on doublet with Lupron/Abi/Pred and we made the personal decision to pursue extended pelvic IMRT with boost to avid nodes.
At psa of 0.16 , a PSMA scan showed three sub centimeter retro caval nodes lit up for
metastasis
. His dzx was early metastatic disease. He went on doublet with Lupron/Abi/Pred and we made the personal decision to pursue extended pelvic IMRT with boost to avid nodes.
103532
in
Advanced Prostate Cancer
4 months ago
Evidence that lidocaine (a local anaesthetic) has anti cancer properties
Braz J Anesthesiol 70(5):527–533. https://doi.org/10.1016/j.bjan.2020.04.018 Sun M, Huang S, Gao Y (2021) Lidocaine inhibits the proliferation and
metastasis
of epithelial ovarian cancer through the Wnt/β-catenin pathway.
Braz J Anesthesiol 70(5):527–533. https://doi.org/10.1016/j.bjan.2020.04.018 Sun M, Huang S, Gao Y (2021) Lidocaine inhibits the proliferation and
metastasis
of epithelial ovarian cancer through the Wnt/β-catenin pathway.
Graham49
in
Advanced Prostate Cancer
7 months ago
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