Dad takes coq10 as he also takes low dose statin since many years.
I read someone on this Board write this on an earlier post -
“I was advised not to take CQ10 since it helps the cancer cell recycle glutathione(GHS).
Excess GSH promotes tumor progression, where elevated levels correlate with increased metastasis”
Anyone know more about this subject ? When I do a online search many sites say it is Infact beneficial
while it’s fine to get opinions from our group , even check AIs on the web …… ultimately your final and most important answer would be consulting with your pcp, oncologist and / or pallitive care group. Only your medical team will know all the possible interactions with your father’s treatment plan , along with considerations of his tests and plans of actions. Just IMHO.
Over the last several years, my medical teams have made me change several of the large number of supplements I take daily. My team checks my mds and supplements four times a year.
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my experience generally is mainstream doctors hardly know anything about supplements 😊❤️
You are trusting your father’s life with those same doctors aren’t you ? There can be many circumstances where your suppliments can interfere with or post a health risk . A good example is the popular suppliment lycopene. Lycopene can slow blood clotting when bleeding occurs. If you are taking prescription NSAIDS and develop intestinal bleeding, Lycopene could present a danger trying to get the bleeding to stop.
Taking lycopene along with medications that also slow blood clotting might increase the risk of bruising and bleeding. Web.md
In my quarterly review of my suppliments, with my doctors , they had me quit Lycopene in one consultation, for example.
Just say’in
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Did not know this about lycopene. My MO said oh if you want to take it , it’s ok. I bet he does not know this too. !
Well what you are saying is true but it’s also true that they may not know some things 😊
This is a really good discussion. And it highlights that in taking any supplement, whether elemental or herbal etc., there are many considerations.
As for lycopene I do take it as a supplement. It was hard to eat enough tomatoes every day through the week. I'm satisfied right now that no research indicates that it could be a problem in my situation of metastatic prostate cancer. And there are indications it could be helpful too.
As for the clotting factor that's a very interesting concern. Perhaps related, I noticed that apparently lycopene can be helpful when one has various markers of anemia that are typically associated with metastatic prostate cancer.
I haven't noticed my blood being extra runny in terms of any effect of lycopene. But it's good to be reviewing these things!
Yeah, I trust my longevity with my doctors, I follow their advice. I hope that my supplements help me and they give me a feeling that I’m trying to help myself. If my medical team says they want me to quit this or that, I’m on it. Even tho I do have a technical medical degree, my doctors have a combined decades more education and experience that dwarfs mine, I defer to them. lol. At this point in my own life and treatment, supplements are probably meaningless - pointless anyway.
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Maybe Dave Chappelle should do a thing on supplements and cancer.
And as for doctors knowing a lot, and for sure they do, but let's not forget that they've been promoting this whole business about saturated fat ever since Doctor Ancel Keys faked his seven countries study.
And the Diabetes Association, in consultation with expert doctors, recommends multiple servings of whole grains everyday.
And also PSA testing is a bad thing because people end up being over-treated afterwards. By doctors!
No misunderstanding that I am very grateful that by luck I ended up with great doctors!
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Truth, my man.
Yeah, I guess. I , somehow, miss out on a “ lot “ or something. Doctors promoting some kind of fat, big pharmaceutical… stuff like that. I’ve never personally run into any of that with my 5 doctors promoting anything and I guess I’ve never been in the same room with big pharma that I know of. I do see a lot of pharmaceutical ads on TV tho. I kill the sound on those usually. I don’t read the “ junk “ on the web , back in the IRC flame war days I made up half of the stuff anyone read on there … myself. I know what hearsay and 2nd hand speak is worth , especially since “ we “ all tried to screw each other into the ground to own control of a IRC channel. I’ve made up some whopper stuff that people bought totally into. and laughed my arse off when they did. Same with politics, I’ve never been interested in politics. Where I come from in Appalachia , anyone in government is evil and if politicians lips are moving , they are lies. I’m headed towards 80 years old and avoiding politics has never let me down. Never made a difference I’m aware of and I’m keeping it that way. I keep my life in the real time , here and now. Very simple , clean and sparkling clear.
I worked for the mid level federal government over 32 years and never personally experienced a single crumb of “ deep state “ or anti something planning. My experience was entirely entrenched GS workers desperately clinging to their “ permanent “ , hard to get , well paying , firing proof job. Better not get in between them and that job. Political talk / discussion was forbidden on the job …. same with race and sexism…. blurt “ any “ of that stuff out and half a dozen people would report you and you’d be in HR the next morning getting that written reprimand. You could get sent home for 3 days for displaying a political slogan or flag in your office / cubicle.
Im just an old , bird in the hand country boy, revenuers in the county … get your gun , politicians handing out flyers , watch how fast we sent that carpet bager back to NYC. lol big pharma ??? , I’m pretty sure they ( even if there was such a thing ) don’t have any interest in me. If “ that stuff “ actually exists ( like big foot and that witch in the next town over ) , it’s got nothing to do with me “ now “ anyway. lol it’s irrelevant to the bone. Most of it is good for a laugh sometimes.
Just say’in
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From what I read, you can increase the potency of the tomato by heating it a little and then spreading some black pepper on them. I don't remember by what factor though.
100% Mascouche - apparently cooking the tomatoes results in cell wall breach and then you can access the lycopene. It's probably essential. And it's in nicely with regular cuisine. The challenge is getting enough tomatoes every day! So I went with the supplement.
You can eat tomato paste. One can with every meal.
Exactly. It’s the opposite. This kind of question is the main reason for this group to even exist.
The problem is that doctors in general do not trust the kind of data that support supplements. History tells us that uncontrolled trials are often wrong for a variety of reason. There are very few placebo controlled trials involving supplements. As a consequence your doctor will seem uninformed. This does not mean supplements don’t work. It just means there is limited information both about benefit and side effects. Controlled trials are expensive and there is little financial support for studying supplements unless they are used by lots of people.
My motto is, unless he needs it to treat a deficiency, don't take it. Your dad's diet should be the source of all necessary nutrition.
quite okay to take. Protects the mitochondria.
Sone say otherwise - for cancers. That’s the confusion
you need ubiquinol/coq10 supplements if you’re taking statins. Statins reduce coq10 and reduce energy levels in many prone who take statins. Have you seen any studies that say coq10 promotes cancer growth? It’s always possible that it can increase the growth in a small percentage of prostate cancers, but I haven’t found any studies that indicate this to be the case with a significant percentage of men. You could try stopping it’s use to see off the growth rates slows. Certain supplements such as folate sometimes show increased growth but I haven’t found data showing this with ubiquinol or coq10.
Not just statins. Some high blood pressure medications, such as beta-blockers and diuretics, can also lower CoQ10 levels. And they can lower potassium levels as well, which ironically, contributes to high blood pressure. So when on those meds, we may want to eat things with more potassium and more CoQ10.
Can statins lower coq10 levels?
I don't understand why you are asking me "Can statins lower coq10 levels?" when you yourself have written "Statins reduce coq10 and reduce energy levels in many prone who take statins.". Are you second-guessing yourself? 
But to answer you, it surely seems that way. Here is an old study from 2004 which says that the decrease in CoQ10 was evident just 14 days after starting statins: jamanetwork.com/journals/ja...
There is some evidence that statins (Lipitor, Crestor) deplete the cellular supply of CoQ10. So, if one is on a statin, it would be a good supplement to take. Otherwise, I'm not sure it is of any benefit.
So..how does one determine they may be low or deficient of CoQ10? Patients are to quick to pop supplements. I wish my PMP would test regularly for deficiency but he doesn't.
I'm not sure if there is a readily available test. If you are on a statin, you should consider taking that supplement.
This from the FLCCC Alliance group(covid19criticalcare.com/):
Antioxidant supplements (vitamins A, C, and E; coenzyme Q10, and N-acetyl cysteine) should be
avoided in patients with cancer. In an experimental model, Wang et al demonstrated that
vitamin C, vitamin E and n-acetylcysteine (NAC) increased tumor angiogenesis by BACH1
mechanism (redox-sensitive transcription factor BTB and CNC homology 1). (411)These
antioxidants should specifically be avoided in patients undergoing chemotherapy and
radiotherapy, as these interventions act largely by increasing oxidant injury, which is minimized
by antioxidant supplements. (412, 413) Paradoxically, while oral vitamin C is a potent
antioxidant, (414) high-dose intravenous vitamin C generates reactive oxygen species that
potentiates the effects of chemotherapy and radiation therapy (see section on intravenous
vitamin C).
Is that just when chemotherapy and radiation is ongoing?
We all walk slightly different paths. Be absolutely sure that you have a medical team that you trust. I consider myself fortunate in that I have that. I also have the position that I don't want to become the 'expert' in all things medical. I'll leave that to someone else who has spent a lifetime in that profession. So, I keep things simple and leave the big decisions to my medical staff. Having said that:
My experience: I used to take CoQ10, however, about a decade or so ago my cardiologist (heart doctor) told me to stop due to new research then and continues to reinforce that decision ever since. My cardiologist is part of a group that meets weekly to review cases and research, so when he tells me that, I believe him.
That's my path. Godspeed in yours!
PS: I had heart issues (3 stents - still working great) before prostate cancer. Urologist & Oncologist both warned of interactions with Atorvastin when adding ADT (androgen deprivation therapy) meds. However, Cardiologist says keep taking statin as it's still doing something, and he added Zetia.
thanks. So your coq10 was stopped for reasons unrelated to cancer ?
Taking Creatine while on Zytiga medicine
IP6 supplementation ok during radiation?
Are my PSA results with Abiraterone (Zytiga) OK?
Plan B: dashed or still ok?
Anyone taking Avodart (Dutasteride) as your only form of ADT?
