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Metformin Inhibits Prostate Cancer Progression by Targeting Tumor-Associated Inflammatory Infiltration
In this study, we demonstrated that metformin is capable of inhibiting TAM recruitment both in vivo and in vitro and reduced TAM recruitment concurrently accompanied by less tumor cell
metastasis
.
In this study, we demonstrated that metformin is capable of inhibiting TAM recruitment both in vivo and in vitro and reduced TAM recruitment concurrently accompanied by less tumor cell
metastasis
.
pjoshea13
in
Advanced Prostate Cancer
5 years ago
Cancer cell dormancy: mechanisms and implications of cancer recurrence and metastasis
He asked that I start a new thread by re-posting the paper: "Cancer cell dormancy: mechanisms and implications of cancer recurrence and
metastasis
" [1]. I hesitated since many will find the paper hard-going. But I have added a few notes that might help. ...
He asked that I start a new thread by re-posting the paper: "Cancer cell dormancy: mechanisms and implications of cancer recurrence and
metastasis
" [1]. I hesitated since many will find the paper hard-going. But I have added a few notes that might help. ...
pjoshea13
in
Advanced Prostate Cancer
5 years ago
disappointed
So after 10 months of taking Ibrance and letrozole I have two new liver lesions. The next step for me is Faslodex and a pill I can't remember the name. (just saw doctor yesterday). What side effects should I expect from the faslodex as I'm an academic coach (teacher) and still working. Also, is anyone
So after 10 months of taking Ibrance and letrozole I have two new liver lesions. The next step for me is Faslodex and a pill I can't remember the name. (just saw doctor yesterday). What side effects should I expect from the faslodex as I'm an academic coach (teacher) and still working. Also, is anyone
Cshipley123
in
SHARE Metastatic Breast Cancer
5 years ago
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CT Scan with Contrast.
They want to check my abdominal lymph nodes for any
metastasis
of the superficial, yet high grade (malignant), urinary bladder tumors. According to the pathology report, most were low grade with only a microinvasion into membranous tissue.
They want to check my abdominal lymph nodes for any
metastasis
of the superficial, yet high grade (malignant), urinary bladder tumors. According to the pathology report, most were low grade with only a microinvasion into membranous tissue.
Sharp5Flat13
in
Lung Conditions Community Forum
6 years ago
Aspirin, metformin and propranolol
Aspirin reduced risk of adenocarcinoma with metastases at initial diagnosis and risk of
metastasis
on subsequent follow up of patients initially without metastases.
Aspirin reduced risk of adenocarcinoma with metastases at initial diagnosis and risk of
metastasis
on subsequent follow up of patients initially without metastases.
kaptank
in
Advanced Prostate Cancer
5 years ago
CBD Oil
My father was recently diagnosed with adenocarcinoma of the lungs, with
metastasis
to lymph nodes in the chest and check. We are currently waiting for his MRI scan results to see if it spread to his brain. He will need chemo and radiation, but I also want him to start using CBD oil.
My father was recently diagnosed with adenocarcinoma of the lungs, with
metastasis
to lymph nodes in the chest and check. We are currently waiting for his MRI scan results to see if it spread to his brain. He will need chemo and radiation, but I also want him to start using CBD oil.
Nurse123456
in
Lung Cancer Support
6 years ago
Post chemo, axillary clearance and radiotherapy, breast Lymphoedema, but getting low. MBC
Hi everyone, I’m on Letrozole and get diarrhoea, and slight dizziness, has anybody changed drugs? Should I bother my oncologist? Thank you to everyone on this sight x
Hi everyone, I’m on Letrozole and get diarrhoea, and slight dizziness, has anybody changed drugs? Should I bother my oncologist? Thank you to everyone on this sight x
123048
in
SHARE Metastatic Breast Cancer
5 years ago
Dehydration and Ibrance
Hi everyone, I have been using Ibrance and Fulvestrant injection since July aside facts have been tolerable but this last month I have been getting dehydrated I drink plenty of fluids but still dehydrated and I've never had that problem before. I was wondering if anyone else is having the same problem
Hi everyone, I have been using Ibrance and Fulvestrant injection since July aside facts have been tolerable but this last month I have been getting dehydrated I drink plenty of fluids but still dehydrated and I've never had that problem before. I was wondering if anyone else is having the same problem
Villazon
in
SHARE Metastatic Breast Cancer
5 years ago
Liver mets
Fall of '14 was diagnosed at age 37 w/ stage 2 bc. Bilat mastectomy, 4 rounds of chemo then put on Tamoxifen. No scans recommended, just PE's & bldwork. Fall of '17 had sensitivity on my left upper sternum. Dr wrote it off as cartilage soreness. Finally in Feb '18 a lump appeared in that area. Rad, bone
Fall of '14 was diagnosed at age 37 w/ stage 2 bc. Bilat mastectomy, 4 rounds of chemo then put on Tamoxifen. No scans recommended, just PE's & bldwork. Fall of '17 had sensitivity on my left upper sternum. Dr wrote it off as cartilage soreness. Finally in Feb '18 a lump appeared in that area. Rad, bone
thorson327
in
SHARE Metastatic Breast Cancer
5 years ago
Happy & Hello
Hello Ladies My name is Chara and i am so happy that i found a blog for metastatic breast cancer. Now I am 35 and i get diagnosed before 5 years when i was 30. I had my mastectomy at the day of my birth (!!!) So....4 years later and as i thought that everything was alright it came to my life again in
Hello Ladies My name is Chara and i am so happy that i found a blog for metastatic breast cancer. Now I am 35 and i get diagnosed before 5 years when i was 30. I had my mastectomy at the day of my birth (!!!) So....4 years later and as i thought that everything was alright it came to my life again in
CharaMasiakou
in
SHARE Metastatic Breast Cancer
5 years ago
My first Post. Guidance needed please.
A bone scan showed a possible
metastasis
in a rib and four nodules in my lungs two 10mm across and the others half the size. They started me off on zoladex in January but held off chemo until they did a biopsy on the lung nodules to determine the type of cancer it was.
A bone scan showed a possible
metastasis
in a rib and four nodules in my lungs two 10mm across and the others half the size. They started me off on zoladex in January but held off chemo until they did a biopsy on the lung nodules to determine the type of cancer it was.
riichardd
in
Advanced Prostate Cancer
5 years ago
Choice of Zytega vs chemotherapy
I was recently diagnosed with prostate cancer with
metastasis
to multiple areas of the spine and pelvis. I have started Firmagon injections, 2 thus far and psa has dropped from 22 to 0.5 in 5 weeks.
I was recently diagnosed with prostate cancer with
metastasis
to multiple areas of the spine and pelvis. I have started Firmagon injections, 2 thus far and psa has dropped from 22 to 0.5 in 5 weeks.
Dino24
in
Advanced Prostate Cancer
6 years ago
We made it home
They think this BOOP is also covering
metastasis
in what we always refer to his "good lung". New area near collar bone and stomach still growing. At present he can not resume any chemo due to lungs have to cleared from this BOOP. After 3 1/2 weeks no improvement.
They think this BOOP is also covering
metastasis
in what we always refer to his "good lung". New area near collar bone and stomach still growing. At present he can not resume any chemo due to lungs have to cleared from this BOOP. After 3 1/2 weeks no improvement.
janiceowens1957
in
Lung Cancer Support
6 years ago
My message: Advanced MPCa patients should be seeing a leading genitourinary oncologist!
Tests ordered by my MD Anderson oncologist (not on the radar of my general oncologist or urologist) show that the largest area of
metastasis
, the area where my prostate used to be, is now undetectable.
Tests ordered by my MD Anderson oncologist (not on the radar of my general oncologist or urologist) show that the largest area of
metastasis
, the area where my prostate used to be, is now undetectable.
tallguy2
in
Advanced Prostate Cancer
6 years ago
Prostate surgery question
Ok, should I request the removal of my prostate even though my doctors are saying that there is no point in doing so since it’s
metastasis
to my lymph nodes?
Ok, should I request the removal of my prostate even though my doctors are saying that there is no point in doing so since it’s
metastasis
to my lymph nodes?
Doug47
in
Advanced Prostate Cancer
6 years ago
Newly Diagnosed but Recurrent
Hello Everyone, I was just diagnosed with metastatic breast cancer in October 2018. This is my second bout with breast cancer. I was initially diagnosed in August 2013 and I also found out I am BRCA1. I was cancer-free for five years before I found out that the cancer had returned and had spread to distant
Hello Everyone, I was just diagnosed with metastatic breast cancer in October 2018. This is my second bout with breast cancer. I was initially diagnosed in August 2013 and I also found out I am BRCA1. I was cancer-free for five years before I found out that the cancer had returned and had spread to distant
Topaz_77
in
SHARE Metastatic Breast Cancer
6 years ago
Nadir Testerone
Gleason score 8 , many
metastasis
. Thoughts? Has had 6 rounds chemo.
Gleason score 8 , many
metastasis
. Thoughts? Has had 6 rounds chemo.
Cynthgob
in
Advanced Prostate Cancer
6 years ago
Ibrance + Letrozole just stopped working
19 months after reaching NED with Ibrance and Letrozole + Xgeva injections , the regime failed ! New mets to bones found in the last Pet Ct . I am a Novo mbc to bones from Feb. 2017 , HR + , HER2 - neg . I am 43 old and I have 2 kids 9 and 12 old . My oncologist suggests me a new option of treatment
19 months after reaching NED with Ibrance and Letrozole + Xgeva injections , the regime failed ! New mets to bones found in the last Pet Ct . I am a Novo mbc to bones from Feb. 2017 , HR + , HER2 - neg . I am 43 old and I have 2 kids 9 and 12 old . My oncologist suggests me a new option of treatment
Gal1975
in
SHARE Metastatic Breast Cancer
6 years ago
Urologist appt about frequent urination
That took me back a bit, he was saying that advance prostate
metastasis
patients who are younger are having their prostates and lymph’s removed but, there isn’t enough data to support that process to be the answer.
That took me back a bit, he was saying that advance prostate
metastasis
patients who are younger are having their prostates and lymph’s removed but, there isn’t enough data to support that process to be the answer.
Doug47
in
Advanced Prostate Cancer
6 years ago
Afinitor and faslodex
Has anyone been on Afinitor and Fulvestrant/Faslodex I’m going to be starting in a couple weeks and I’m just wondering what the side effects are and how long it had been successful. Prior to this I have been on Ibrance and letrozole for almost 2 years and it just stopped working.
Has anyone been on Afinitor and Fulvestrant/Faslodex I’m going to be starting in a couple weeks and I’m just wondering what the side effects are and how long it had been successful. Prior to this I have been on Ibrance and letrozole for almost 2 years and it just stopped working.
KarenHale
in
SHARE Metastatic Breast Cancer
6 years ago
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