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Prolactin & Abiraterone
PRL expression was also detected in biopsy samples from bone
metastasis
but not in normal bone tissue, and the serum PRL levels were positively correlated with aBSIs (r = 0.28, p = 0.037). Conclusions: Serum PRL levels are predictive of response to AA in patients with mCRPC.
PRL expression was also detected in biopsy samples from bone
metastasis
but not in normal bone tissue, and the serum PRL levels were positively correlated with aBSIs (r = 0.28, p = 0.037). Conclusions: Serum PRL levels are predictive of response to AA in patients with mCRPC.
pjoshea13
in
Advanced Prostate Cancer
2 years ago
Faslodex and Anastrozole
I have been taking Faslodex injections for 9 months now. I’m doing okay with these. My Oncologist added Anastrozole. I would love anyones input on this combination . I’m feeling a lot of fatigue and nausea daily. Have a beautiful day 🥰. Jen
I have been taking Faslodex injections for 9 months now. I’m doing okay with these. My Oncologist added Anastrozole. I would love anyones input on this combination . I’m feeling a lot of fatigue and nausea daily. Have a beautiful day 🥰. Jen
Rubyln15
in
SHARE Metastatic Breast Cancer
2 years ago
2nd opinion about treatment change?
Dear ladies, friends, I post only rarely on here but come today looking for advice. I was diagnosed 2 yrs ago de novo with 10cm breast tumour and various mets to bones. Palbociclib + letrozole combo made everything go away, until it stopped working 9 months later and new mets started to appear on different
Dear ladies, friends, I post only rarely on here but come today looking for advice. I was diagnosed 2 yrs ago de novo with 10cm breast tumour and various mets to bones. Palbociclib + letrozole combo made everything go away, until it stopped working 9 months later and new mets started to appear on different
Here_now
in
SHARE Metastatic Breast Cancer
2 years ago
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Non-metastatic PCa
I am thinking that i will just continue having side effects with more ADT and whatever may come next…I am wondering if i could stop the hormone therapy and wait until there is
metastasis
. I would appreciate some feedback… Thanks
I am thinking that i will just continue having side effects with more ADT and whatever may come next…I am wondering if i could stop the hormone therapy and wait until there is
metastasis
. I would appreciate some feedback… Thanks
billy1950
in
Advanced Prostate Cancer
2 years ago
MBC is so frustrating
My liver is still growing, quickly, which isn't the norm for invasive ductal carcinoma. I am now off fulvestrant and will be going on xeloda try to get these tumors to shrink tomorrow after blood work gets back. My onocologyst wants to do a biopsy of my liver tumors to see if they are my primary's type
My liver is still growing, quickly, which isn't the norm for invasive ductal carcinoma. I am now off fulvestrant and will be going on xeloda try to get these tumors to shrink tomorrow after blood work gets back. My onocologyst wants to do a biopsy of my liver tumors to see if they are my primary's type
Debbigbang
in
SHARE Metastatic Breast Cancer
2 years ago
Researchers find novel inhibitors that may suppress oncogenesis of metastatic prostate cancer
In previous research we found strong evidence for the involvement of CDK19 in the growth, progression, and
metastasis
of prostate cancer, as well as the development of castration resistance.
In previous research we found strong evidence for the involvement of CDK19 in the growth, progression, and
metastasis
of prostate cancer, as well as the development of castration resistance.
Scout4answers
in
Advanced Prostate Cancer
2 years ago
Treatment side effects..
Hi ladies. Hope you all doing fine. I do have a question regarding Ibrance and letrozole combo. My mom has been on that treatment for 13 months now and it’s been working for her. She was ok for couple of months at the beginning of treatment but recently she’s been experiencing different side effects,
Hi ladies. Hope you all doing fine. I do have a question regarding Ibrance and letrozole combo. My mom has been on that treatment for 13 months now and it’s been working for her. She was ok for couple of months at the beginning of treatment but recently she’s been experiencing different side effects,
SabaAK
in
SHARE Metastatic Breast Cancer
2 years ago
Should I try T replacement again?
So now I'm 75 - I've never had
metastasis
, my HIFU-ravaged prostate is half gone and my PSA seems stable at 1.5 (maybe it would be 3.0 if it were a whole prostate?).
So now I'm 75 - I've never had
metastasis
, my HIFU-ravaged prostate is half gone and my PSA seems stable at 1.5 (maybe it would be 3.0 if it were a whole prostate?).
kapakahi
in
Prostate Cancer Network
2 years ago
Sources of PSA During ADT Break
First I had a local recurrence in 2016 and lymph node (pelvic and abdominal)
metastasis
in 2018. Since then I have been on intermittent Lupron ( 3 month shorts). Currently, I am on my second break from June 2021 (last three month short in March 2021).
First I had a local recurrence in 2016 and lymph node (pelvic and abdominal)
metastasis
in 2018. Since then I have been on intermittent Lupron ( 3 month shorts). Currently, I am on my second break from June 2021 (last three month short in March 2021).
dac500
in
Advanced Prostate Cancer
2 years ago
Lu-177 or Cabazitaxel
His current PSA is greater 34, CT scan shows that
metastasis
is unchanged in comparison to the time he took docetaxel (PSA ≈ 0.29, please see my dad profile for details). However, he sometimes feels hurt/uncomfortable at leg and/or hip.
His current PSA is greater 34, CT scan shows that
metastasis
is unchanged in comparison to the time he took docetaxel (PSA ≈ 0.29, please see my dad profile for details). However, he sometimes feels hurt/uncomfortable at leg and/or hip.
Hidden
in
Advanced Prostate Cancer
2 years ago
My brother has lung cancer
On Friday this week he will receive gamma knife surgery for the
metastasis
. So... we are in shock. He is only 39 years old, very healthy, never smoked. I just wanted to write something somewhere.
On Friday this week he will receive gamma knife surgery for the
metastasis
. So... we are in shock. He is only 39 years old, very healthy, never smoked. I just wanted to write something somewhere.
Hidden
in
The Roy Castle Lung Cancer Foundation
2 years ago
Sulforaphane Dosage?
Is there a recommended dosage of Sulforaphane to help prevent
metastasis
? (BroccoMax supplement suggests 35 mg/day.) As shown in my profile, I had RP in 2018 (Gleason 4+4), 38 radiation sessions in 2019, and PSA has been undetectable since then.
Is there a recommended dosage of Sulforaphane to help prevent
metastasis
? (BroccoMax supplement suggests 35 mg/day.) As shown in my profile, I had RP in 2018 (Gleason 4+4), 38 radiation sessions in 2019, and PSA has been undetectable since then.
Polaris1
in
Advanced Prostate Cancer
2 years ago
ADT+docetaxel first impressions, adding darolutamide
I have a high volume bone
metastasis
. Can I still skip Lupron since the PSA is already within normal range? Are there other ways of administering Lupron? I think people were mentioning a pill, instead of in injection. First dose of docetaxel wasn't too bad.
I have a high volume bone
metastasis
. Can I still skip Lupron since the PSA is already within normal range? Are there other ways of administering Lupron? I think people were mentioning a pill, instead of in injection. First dose of docetaxel wasn't too bad.
Oldie68
in
Advanced Prostate Cancer
2 years ago
Melatonin suppresses the metastatic potential of osteoblastic prostate cancers by inhibiting integrin α 2 β 1 expression
"Advanced prostate cancer often develops into bone
metastasis
, which is characterized by aberrant bone formation with chronic pain and lower chances of survival. No treatment exists as yet for osteoblastic bone
metastasis
in prostate cancer.
"Advanced prostate cancer often develops into bone
metastasis
, which is characterized by aberrant bone formation with chronic pain and lower chances of survival. No treatment exists as yet for osteoblastic bone
metastasis
in prostate cancer.
pjoshea13
in
Advanced Prostate Cancer
2 years ago
Resveratrol Revisited. For Gut Microbiome.
A second domain, in my perspective are interventions, therapeutic and lifestyle which may slow the progression of prostate cancer through ever more advanced stages if invasiveness, treatment resistance, hormone independence and seeding
metastasis
. These are described in "The Hallmarks of Cancer".
A second domain, in my perspective are interventions, therapeutic and lifestyle which may slow the progression of prostate cancer through ever more advanced stages if invasiveness, treatment resistance, hormone independence and seeding
metastasis
. These are described in "The Hallmarks of Cancer".
MateoBeach
in
Advanced Prostate Cancer
2 years ago
Experience with the drug Xtandi
Scans revealed no
metastasis
. Treatment was external radiation and Lupron injections. PSA reading on 6/19/2018 was 0.32 with the latest reading 01/12/2022 of 4.78. A suggested treatment involves the drug Xtandi. Does anyone have experience with this drug. Thanks
Scans revealed no
metastasis
. Treatment was external radiation and Lupron injections. PSA reading on 6/19/2018 was 0.32 with the latest reading 01/12/2022 of 4.78. A suggested treatment involves the drug Xtandi. Does anyone have experience with this drug. Thanks
cedaral
in
Prostate Cancer Network
2 years ago
Amg757 trial
His bone
metastasis
is spreading after 18 rounds of Cisplatin and Etoposide last year and this year he’s on Docataxel his 5 th of 6, and it doesn’t seem to be effective in reducing the bone Mets. Any info is appreciated. Thank you!
His bone
metastasis
is spreading after 18 rounds of Cisplatin and Etoposide last year and this year he’s on Docataxel his 5 th of 6, and it doesn’t seem to be effective in reducing the bone Mets. Any info is appreciated. Thank you!
Jzner
in
Advanced Prostate Cancer
2 years ago
Targeted Drugs and Need for Genetic Testing??
This is one of today's posts in Practice Update: STORY OF THE WEEK Published in Metastatic Breast Cancer · April 08, 2022 .... CDK4/6 Inhibitor Outcomes in Patients With Advanced Breast Cancer With Germline Pathogenic Variants in DNA Repair–Related Genes TAKE-HOME MESSAGE "This retrospective study
This is one of today's posts in Practice Update: STORY OF THE WEEK Published in Metastatic Breast Cancer · April 08, 2022 .... CDK4/6 Inhibitor Outcomes in Patients With Advanced Breast Cancer With Germline Pathogenic Variants in DNA Repair–Related Genes TAKE-HOME MESSAGE "This retrospective study
Hazelgreen
in
SHARE Metastatic Breast Cancer
2 years ago
New nodules?
Been on Ibrance and Arimidex for 30 cycles for lung
metastasis
found in May of 2019. I will see oncologist next Tuesday to hear his opinion. Not sure whether to freak or be settled that no activity seen on scan. Opinions?
Been on Ibrance and Arimidex for 30 cycles for lung
metastasis
found in May of 2019. I will see oncologist next Tuesday to hear his opinion. Not sure whether to freak or be settled that no activity seen on scan. Opinions?
Beattheodds
in
SHARE Metastatic Breast Cancer
2 years ago
Sick again
So every month since I had Covid in December I’ve been sick with something. I had a UTI then the reaction to the new Faslodex and now I’m home sick with the worst cold ever. I don’t know if this is from stress or just my immune system saying quit your job. Anyone have this experience?
So every month since I had Covid in December I’ve been sick with something. I had a UTI then the reaction to the new Faslodex and now I’m home sick with the worst cold ever. I don’t know if this is from stress or just my immune system saying quit your job. Anyone have this experience?
Puppy_love
in
SHARE Metastatic Breast Cancer
2 years ago
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