Experiences with

Metastasis

Human trials remain essential before this strategy can reach patients, but it could reshape how metastasis is prevented and treated. https://prostatewarriors.com/2025/01/11/drug-repurposing-against-metastasis/

I am a 62-year-old woman with a history of metastatic ER positive, HER-2/neu negative breast cancer with metastasis to bone as well as adenopathy to the right supraclavicular area. Right axillary biopsy demonstrated ER positive, HER-2/neu 2+, FISH negative disease.

Actually I did not even know that there were stress-aggravated cancer metastasis...but I suppose that stress is a darn bad thing always! Kaempferol enhances the secretion of α2M, a protease inhibitor that suppresses tumor cell invasion and metastasis.

We found out yesterday mums OC has metastasised to the brain. We don’t have a treatment plan yet although radiotherapy has been mentioned. Does anyone have any experience, knowledge or advice for this diagnosis. I’m devastated for my mum who has spent the last 3 years since diagnosis in relatively good

I jave neen daignosed with Metastasis breast cancer stage 4. I am on capecitabine 500 mg 2 tabs and capecitabine 150 mg tablet 2 tabs . Two weeks tablets and one week off . Now my onc wants to change to faslodex .but I dont know how many sesions. Please tell me if it is pain ful

I wrote last week about a spot on my right lung, that my oncologist thought it was not prostate metastasis but bona find lung cancer. They did a PET scan and a brain scan last week, and fortunately there was no evidence of any metastasis in the brain.

My Abdo and Pelvis came back with no evidence of metastasis. My Chest one came back finding two (2mm and 5mm) nodules in my lung as well as some opacities (which I had before). It says no specific evidence of metastasis and that these are commonly found but will need to be followed.

Three research groups recently independently elucidated the genetic and epigenetic mechanisms driving prostate cancer metastasis.

The doctor says it’s definitely metastasis to the lung. I’m wondering if anyone had or have this problem and what the dr started them on. I know this was kind of long, sorry.

After many years on oral meds for bone mets, I recently have been diagnosis with breast cancer which has metastasized to my pancreas. I also have mutated rom ER+ HER low to triple negative. I completed 15 rounds of radiation along with simultaneous weekly infusions of Taxol. I have had stents put in

it is very promising in vivo and in vitro, esp for lung metastasis ”In a study published in Clinical Cancer Research, the researchers demonstrate that the compound can reduce lung metastasis in mice by over 90 per cent, while also shrinking the primary tumour site.”

The PSA is increasing (in the teens), but again, no sign of metastasis on the scan.

Does the following psma scan report findings considered a visceral metastasis like metastasis to liver, lungs, etc. ? “SPLEEN: No new suspicious uptake. Slightly decreased conspicuity of mild uptake at the splenic hilum, image 168, SUV 9.9, previously 10.9.” Thank you.

But the fact that they are both hormonal cancers and the fact that this molecule is targeted (very succesfully in vivo) to bone metastasis, makes me say "keep an eye on this!"

This study came across my feed about interleukin 30 (which promotes PCa metastasis growth) which is being edited using Crisper technology. Hopefully leading to a new treatment! https://crisprmedicinenews.com/news/il-30-knockout-as-a-novel-therapeutic-strategy-for-metastatic-prostate-cancer/

a radio ligand that seems to target bone metastasis while sparing bone marrow https://www.pharmaceutical-technology.com/data-insights/tin-117m-dtpa-serene-bone-metastasis-likelihood-of-approval/

Marked improvement in radiotracer avid osteoblastic metastasis and marked improvement in radiotracer avid nodal metastasis. Radiotracer avid disease in the prostate has also markedly improved." Bear in mind that I was diagnosed as stage 4, Gleason 9, and I'm now 87 years old.

Looking for any information regarding liver metastasis from ovarian cancer. I believe I have a 4cm tumor in my liver. What is the treatment plan for this? More importantly, what is the time frame? Am I looking at my last few months? Any information is much appreciated. God Bless you all.

Because one of the worst enemies is not the prostate cancer itself, but the metastasis, especially to the bones! Nanotechnologies seem to be on their way for precision payload delivery to our bones! https://www.nature.com/articles/s41413-024-00356-2

MMP7, an enzyme involved in the breakdown of the extracellular matrix, is often overexpressed in aggressive cancers, including prostate cancer, facilitating tumor invasion and metastasis. Very early stage, but consider that till not long ago, this enzyme was considered undruggable.