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Docxtel triple therapy?
Thank you for sharing your thoughts. My dad--81, advanced metastatic castrate resistant Diagnosed at 79 with stage 4 met 8 bones, including skull, no Gleason, never even saw a urologist. Diagnosed in ER and sent straight to the oncologist and palliative care doctor. PSA initially at 137 Lupron
Thank you for sharing your thoughts. My dad--81, advanced metastatic castrate resistant Diagnosed at 79 with stage 4 met 8 bones, including skull, no Gleason, never even saw a urologist. Diagnosed in ER and sent straight to the oncologist and palliative care doctor. PSA initially at 137 Lupron
lgutman
in
Advanced Prostate Cancer
4 months ago
Estradiol, QoL and inflammation
Although I have been following the exchanges of this group for several months, this my first posting. I have (at 79) learned a lot from the pooled knowledge and experience of the group members. My inquiry ties in with posts regarding estradiol and the PATCH trial that have appeared the last couple
Although I have been following the exchanges of this group for several months, this my first posting. I have (at 79) learned a lot from the pooled knowledge and experience of the group members. My inquiry ties in with posts regarding estradiol and the PATCH trial that have appeared the last couple
Cliff-hanger
in
Advanced Prostate Cancer
4 months ago
Triplet and now Radiation?
Hi all - just wanting your thoughts on this. In my profile you would see full details but I will summarize here. 50yr old diagnosed Aug 2nd with PCA with spread to L5 and pubic bone. Original PSA was around 9 and put on Casodex for month, then Lupron every 3 months, plus Darolutamide. Just completed
Hi all - just wanting your thoughts on this. In my profile you would see full details but I will summarize here. 50yr old diagnosed Aug 2nd with PCA with spread to L5 and pubic bone. Original PSA was around 9 and put on Casodex for month, then Lupron every 3 months, plus Darolutamide. Just completed
Yzinger
in
Advanced Prostate Cancer
4 months ago
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Removal of contralateral testicle
To further reduce risk of recurrence of NHL DLBCL the contralateral testicle was removed as well. Surgery was successful. Now waiting two months and then check PSA and Testosterone. Still hormone sensitive, but no further Lupron required. Looking forward.
To further reduce risk of recurrence of NHL DLBCL the contralateral testicle was removed as well. Surgery was successful. Now waiting two months and then check PSA and Testosterone. Still hormone sensitive, but no further Lupron required. Looking forward.
Nusch
in
Advanced Prostate Cancer
4 months ago
Early Results from Transdermal Estrogen PATCH trial - 2
Here's some charts comparing Lupron ADT to transdermal estrogen (TDE) therapy for High Risk and Very High Risk men with prostate cancer. The upper chart shows the percentage of men that have been castrated to a testosterone level < 50 ng/dL after 1 month of treatment. For Lupron, only 65% of HR/VHR
Here's some charts comparing Lupron ADT to transdermal estrogen (TDE) therapy for High Risk and Very High Risk men with prostate cancer. The upper chart shows the percentage of men that have been castrated to a testosterone level < 50 ng/dL after 1 month of treatment. For Lupron, only 65% of HR/VHR
janebob99
in
Prostate Cancer Network
4 months ago
Early Results from Transdermal Estrogen PATCH trial - 2
Here's some charts comparing Lupron ADT to transdermal estrogen (TDE) patch therapy for High Risk and Very High Risk men with prostate cancer. The upper chart shows the percentage of men that have been castrated to a testosterone level < 50 ng/dL after 1 month of treatment. For Lupron, 65% of HR/
Here's some charts comparing Lupron ADT to transdermal estrogen (TDE) patch therapy for High Risk and Very High Risk men with prostate cancer. The upper chart shows the percentage of men that have been castrated to a testosterone level < 50 ng/dL after 1 month of treatment. For Lupron, 65% of HR/
janebob99
in
Advanced Prostate Cancer
4 months ago
Early Results from Transdermal Estrogen PATCH trial
Here are some Early Results from the first year of the Transdermal Estrogen PATCH trial. References are available on their website at: http://patch.mrcctu.ucl.ac.uk. The cohort was men with High or Very High Risk prostate cancer. Stage T3 (73%) and Stage T4 (14%), baseline PSA = 35 ng/mL. The upper
Here are some Early Results from the first year of the Transdermal Estrogen PATCH trial. References are available on their website at: http://patch.mrcctu.ucl.ac.uk. The cohort was men with High or Very High Risk prostate cancer. Stage T3 (73%) and Stage T4 (14%), baseline PSA = 35 ng/mL. The upper
janebob99
in
Advanced Prostate Cancer
4 months ago
Early Results of Estrogen PATCH trial - 1
Here are some Early Results from the first year of the Transdermal Estrogen PATCH trial. References are available on their website at: http://patch.mrcctu.ucl.ac.uk. The cohort was men with High or Very High Risk prostate cancer. Stage T3 (73%) and Stage T4 (14%), baseline PSA = 35 ng/mL. The upper
Here are some Early Results from the first year of the Transdermal Estrogen PATCH trial. References are available on their website at: http://patch.mrcctu.ucl.ac.uk. The cohort was men with High or Very High Risk prostate cancer. Stage T3 (73%) and Stage T4 (14%), baseline PSA = 35 ng/mL. The upper
janebob99
in
Prostate Cancer Network
4 months ago
Can post-BCR use of Tadalafil add risk?
Hello - My family doctor says no, but I have a lingering concern about it, despite the fact that my family doctor claims there is no relationship and says I can continue to use it. Firstly, I used it after the RP, and had a fast BCR at 2 years. (sure it could have been something else) Though on
Hello - My family doctor says no, but I have a lingering concern about it, despite the fact that my family doctor claims there is no relationship and says I can continue to use it. Firstly, I used it after the RP, and had a fast BCR at 2 years. (sure it could have been something else) Though on
jackwfrench
in
Advanced Prostate Cancer
4 months ago
Estrogen ADT vs Lupron ADT
Here's a chart showing % of men who have a given condition, comparing Estrogen ADT versus Lupron ADT. There's big reduction in hot flashes, and improvements in libido, when taking supplemental Estrogen. Estrogen increases gynecomastia (enlarged breasts), however. Bob
Here's a chart showing % of men who have a given condition, comparing Estrogen ADT versus Lupron ADT. There's big reduction in hot flashes, and improvements in libido, when taking supplemental Estrogen. Estrogen increases gynecomastia (enlarged breasts), however. Bob
janebob99
in
Prostate Cancer Network
4 months ago
VERY limited exercise… am I kidding myself
84 years old with mPCa and a bum left knee. Diagnosed April ‘23, 6-month Lupron, had 4 rounds of Docetaxal, presently on Nubeqa. I know there are significant benefits to exercise, and I have pretty much convinced myself that I am doing the best I can for now … but it’s not much. I walk around the
84 years old with mPCa and a bum left knee. Diagnosed April ‘23, 6-month Lupron, had 4 rounds of Docetaxal, presently on Nubeqa. I know there are significant benefits to exercise, and I have pretty much convinced myself that I am doing the best I can for now … but it’s not much. I walk around the
Pinkyboy
in
Advanced Prostate Cancer
4 months ago
No Osteoporosis with Estrogen Patch Therapy
These plots compare results from the Phase-II randomized trial (PATCH) comparing estrogen patch therapy to Lupron ADT. These plots show that Lupron ADT causes bone loss, while estrogen patch therapy has either no bone loss or increased bone mineral density (BMD) over time. Bob
These plots compare results from the Phase-II randomized trial (PATCH) comparing estrogen patch therapy to Lupron ADT. These plots show that Lupron ADT causes bone loss, while estrogen patch therapy has either no bone loss or increased bone mineral density (BMD) over time. Bob
janebob99
in
Prostate Cancer Network
4 months ago
Castration by Estrogen Patch
This plot shows a dramatic decrease in testosterone and PSA after starting estrogen patch therapy, indicating that transdermal estrogen (TDE) therapy effectively castrates men, and with fewer side effects than Lupron ADT.
This plot shows a dramatic decrease in testosterone and PSA after starting estrogen patch therapy, indicating that transdermal estrogen (TDE) therapy effectively castrates men, and with fewer side effects than Lupron ADT.
janebob99
in
Prostate Cancer Network
4 months ago
The paradigm has shifted - castrate resistance.
It now appears that I’ve entered the land of castrate resistance and further ADT vacations are no longer in the plan. My T level recovered much more quickly during the last vacation than during previous vacations, and my PSA rose correspondingly. At 4 months my T level was 325 and my PSA was 4. Another
It now appears that I’ve entered the land of castrate resistance and further ADT vacations are no longer in the plan. My T level recovered much more quickly during the last vacation than during previous vacations, and my PSA rose correspondingly. At 4 months my T level was 325 and my PSA was 4. Another
fireandice123
in
Advanced Prostate Cancer
4 months ago
dad has advanced prostate cancer
my dad has had prostate cancer for a long time. He’s beeen on Lupron and xtandi and some other meds that gave him confusion. At this point he’s 83, it’s in a few ribs, hip (he had hip replacement a few years ago), clavicle, base of skull, spinal areas, spots on lung and liver. I think i covered it all
my dad has had prostate cancer for a long time. He’s beeen on Lupron and xtandi and some other meds that gave him confusion. At this point he’s 83, it’s in a few ribs, hip (he had hip replacement a few years ago), clavicle, base of skull, spinal areas, spots on lung and liver. I think i covered it all
Ckck333
in
Advanced Prostate Cancer
4 months ago
Lupron
Do not use Lupron if you have any kind of heart condition. I have a replaced Mitral Valve and was on the Lupron shots every three months for 18 months. Every time I would get a Lupron shot, I could feel it hit my body within 20 minutes with flu like conditions... very tired. When I had my Luron shot
Do not use Lupron if you have any kind of heart condition. I have a replaced Mitral Valve and was on the Lupron shots every three months for 18 months. Every time I would get a Lupron shot, I could feel it hit my body within 20 minutes with flu like conditions... very tired. When I had my Luron shot
Teddski
in
Prostate Cancer Network
4 months ago
drug vacation
Who had PSA level come back all the way down after a drug vacation? I want to do a holiday when my Lupron wears off in a couple months. PSA now is .053. Been on Lupron and abi for six years.
Who had PSA level come back all the way down after a drug vacation? I want to do a holiday when my Lupron wears off in a couple months. PSA now is .053. Been on Lupron and abi for six years.
gsun
in
Advanced Prostate Cancer
4 months ago
no sleep tonight
crap ….time zone .. nothing goes well bummed. Anyone delete people or contacts that disappoint you? Lupron shot , plus fuck you supplement pills .. so bummed ,people disappoint …I do it regularly l.
crap ….time zone .. nothing goes well bummed. Anyone delete people or contacts that disappoint you? Lupron shot , plus fuck you supplement pills .. so bummed ,people disappoint …I do it regularly l.
Yokohama2023
in
Advanced Prostate Cancer
4 months ago
Staring at my unopened bottle of Orgovyx
Well, D-day (or maybe O-day) has arrived (thank you FED-X). I'm about to do a swan dive into my battle against my PCa. After a week of searching for this stuff, my clinic found it in Louisville Kentucky at a pharmacy called Onco360. Not exactly a neighborhood corner market with me living on an island
Well, D-day (or maybe O-day) has arrived (thank you FED-X). I'm about to do a swan dive into my battle against my PCa. After a week of searching for this stuff, my clinic found it in Louisville Kentucky at a pharmacy called Onco360. Not exactly a neighborhood corner market with me living on an island
mababa
in
Advanced Prostate Cancer
4 months ago
Testosterone Recovery for 50% of Men
Here's an updated plot of Testosterone recovery time for 50% of men after stopping Lupron ADT, as a function of ADT duration. For ADT durations less than 20 months, the curve is basically linear with a slope = 1.0 (green line), meaning that the Recovery Time for 50% of men is roughly equal to the ADT
Here's an updated plot of Testosterone recovery time for 50% of men after stopping Lupron ADT, as a function of ADT duration. For ADT durations less than 20 months, the curve is basically linear with a slope = 1.0 (green line), meaning that the Recovery Time for 50% of men is roughly equal to the ADT
janebob99
in
Prostate Cancer Network
4 months ago
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