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Abstract 5086: Acetyl-L-carnitine (ALCAR) inhibits angiogenesis, migration and macrophage recruitment in prostatic cancer cells
I have been reading recent posts about metformin and also AMPK that has good and bad reviews. I just came across this (ALCAR) which I do not remember being discussed. http://cancerres.aacrjournals.org/content/79/13_Supplement/5086 (sorry, could not figure out how to make it a link. You can copy and
I have been reading recent posts about metformin and also AMPK that has good and bad reviews. I just came across this (ALCAR) which I do not remember being discussed. http://cancerres.aacrjournals.org/content/79/13_Supplement/5086 (sorry, could not figure out how to make it a link. You can copy and
keepinon
in
Advanced Prostate Cancer
5 years ago
Activating AMPK and PCa
Hey gang, saw this paper about AMPK activation, which Metformin does, and the effect on PCa: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4480686/ But, also saw this one about IF (Intermittent fasting) and AMPK: http://siimland.com/how-to-increase-ampk-for-fat-burning-and-longevity/ BTW, safe in CA,
Hey gang, saw this paper about AMPK activation, which Metformin does, and the effect on PCa: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4480686/ But, also saw this one about IF (Intermittent fasting) and AMPK: http://siimland.com/how-to-increase-ampk-for-fat-burning-and-longevity/ BTW, safe in CA,
dockam
in
Advanced Prostate Cancer
5 years ago
35 wk scan shows polyhydramnios. Has it caused any baby birth defects or problems?
Hi all, I went into the labour ward with my OH last night as the baby movements I've been experiencing have been getting less. The heartbeat was strong, but the scan showed I had a lot of fluid and she called it polyhydramnios. I was wondering if anyone else has had this and whether it's due to birth
Hi all, I went into the labour ward with my OH last night as the baby movements I've been experiencing have been getting less. The heartbeat was strong, but the scan showed I had a lot of fluid and she called it polyhydramnios. I was wondering if anyone else has had this and whether it's due to birth
Music1
in
Pregnancy and Parenting Support
5 years ago
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Will Kidney function improve after gemzar/cisplatin
I hovered at creatinine of 1.1 to 1.3 during treatment but 4 weeks after treatment it is now 1.7 with egfr of 30. I am actually not very happy with my oncologist as he has not bothered to call me about the results. I saw them on the computer. Also,, went for a cystoscope at which time they did a urinalysis
I hovered at creatinine of 1.1 to 1.3 during treatment but 4 weeks after treatment it is now 1.7 with egfr of 30. I am actually not very happy with my oncologist as he has not bothered to call me about the results. I saw them on the computer. Also,, went for a cystoscope at which time they did a urinalysis
sewon
in
Kidney Cancer Support
5 years ago
Metformin.... OMG!
Has anyone been on Metformin and had hellish diahorrea and stomach cramps! I was ok on 2 tablets a day now moved up to 3 and body seems to be rejecting everything I’m eating. Then there’s the sickness and loss of appetite.... really getting me down 😞 Anyone else suffered on this? Wondering if it’s worth
Has anyone been on Metformin and had hellish diahorrea and stomach cramps! I was ok on 2 tablets a day now moved up to 3 and body seems to be rejecting everything I’m eating. Then there’s the sickness and loss of appetite.... really getting me down 😞 Anyone else suffered on this? Wondering if it’s worth
Shinyhalo1
in
Fertility Network UK
5 years ago
COC protocol
I started with the COC protocol in March of this year. I see numerous posts regarding the use of metformin, statins, and fenbendazole/mebendazole. For those of you that may be interested in the program check out Dr. Daniel Thomas's blog at www.thomashealthblog.com . He is my consulting oncologist associated
I started with the COC protocol in March of this year. I see numerous posts regarding the use of metformin, statins, and fenbendazole/mebendazole. For those of you that may be interested in the program check out Dr. Daniel Thomas's blog at www.thomashealthblog.com . He is my consulting oncologist associated
Kentucky1
in
Advanced Prostate Cancer
5 years ago
Metformin and Prostate Cancer
Just wondering about who might be using Metformin to fight their Prostate Cancer.
Just wondering about who might be using Metformin to fight their Prostate Cancer.
TomNew62
in
Advanced Prostate Cancer
5 years ago
Being prescribed drugs to help with fatty liver and cirrhosis
My pcp spoke with a no that specializes in liver care at my gastroenterologists office. It was suggested I start to take metformin and a statin to reduce the fat in my liver. It appeared on my last fibroscan that my liver was stiffer and I was downgraded to f3. This is supposed to be the most current
My pcp spoke with a no that specializes in liver care at my gastroenterologists office. It was suggested I start to take metformin and a statin to reduce the fat in my liver. It appeared on my last fibroscan that my liver was stiffer and I was downgraded to f3. This is supposed to be the most current
Moonsts
in
Living with Fatty Liver and NASH
5 years ago
Creatinine level
I am a chronic diabetic for 30 years and have been taking Glynase mf morning 1 and night 1 and my sugar was almost under control.Recently I have been diagnosed as CKD 3rd stage and in spite of reducing salt and on kidney diet my creatinine level remains at 2.0 to 2.1 always.My nephrologist suggested
I am a chronic diabetic for 30 years and have been taking Glynase mf morning 1 and night 1 and my sugar was almost under control.Recently I have been diagnosed as CKD 3rd stage and in spite of reducing salt and on kidney diet my creatinine level remains at 2.0 to 2.1 always.My nephrologist suggested
anands1952
in
Kidney Disease
5 years ago
PSA dropped to 3.9 this month after rising to 4.3 from the 3.8 two months ago
After the scare last month, I added 1000mg of Metformin to the daily 2gms, doubled the daily Lipitor and Casodex. Maybe the PSA was just an outlier. Still doing IF and CBD oil. Gonna add DIM and Nattokinase this time and check again. Did a 5k race and got a great view of the Queen Mary. I came in 3rd
After the scare last month, I added 1000mg of Metformin to the daily 2gms, doubled the daily Lipitor and Casodex. Maybe the PSA was just an outlier. Still doing IF and CBD oil. Gonna add DIM and Nattokinase this time and check again. Did a 5k race and got a great view of the Queen Mary. I came in 3rd
dockam
in
Advanced Prostate Cancer
5 years ago
Could this have been happening this long without me realising?
Thinking about my current position. Five or six years ago it was winter and I went to bed with a hot water bottle because of lower back pain and when the program I was watching went off I went to top up the water bottle my partner at the time said you have a massive burn on your back that was raw red
Thinking about my current position. Five or six years ago it was winter and I went to bed with a hot water bottle because of lower back pain and when the program I was watching went off I went to top up the water bottle my partner at the time said you have a massive burn on your back that was raw red
buster_uk
in
Pernicious Anaemia Society
5 years ago
Metformin for breast cancer
Hi ladies Just reading the Sunday Times There’s an article about Metformin and how it alters the metabolism of cancer stem cells and can reduce their growth by up to 76% There is a trial starting soon This is one of the drugs prescribed by COC Very interesting Barb xx
Hi ladies Just reading the Sunday Times There’s an article about Metformin and how it alters the metabolism of cancer stem cells and can reduce their growth by up to 76% There is a trial starting soon This is one of the drugs prescribed by COC Very interesting Barb xx
Barbteeth
in
SHARE Metastatic Breast Cancer
5 years ago
Loss of PTEN
I have mCRPC since March. I am presently receiving chemo with taxotere and carboplatin. I have failed xtandi and zytiga. Lymph node tumor biopsy revealed adenocarcinoma, no NE. Genetic profiling revealed loss of PTEN. No other mutations. My question is, what else can I be doing in regards to the
I have mCRPC since March. I am presently receiving chemo with taxotere and carboplatin. I have failed xtandi and zytiga. Lymph node tumor biopsy revealed adenocarcinoma, no NE. Genetic profiling revealed loss of PTEN. No other mutations. My question is, what else can I be doing in regards to the
Rexwaterbury
in
Advanced Prostate Cancer
5 years ago
high B12 not sure on others
lots of symptoms so pretty much had to demand b12 to be tested as on metformin B12 1180 ng/L 180-915 (not supplemented for a few weeks) (dr asked if i was on injections) folate 11.8 ug/L 3.1-19.9) vit d 54 mmol/L anything above 50 is adequate on spatone due to low ferritin
lots of symptoms so pretty much had to demand b12 to be tested as on metformin B12 1180 ng/L 180-915 (not supplemented for a few weeks) (dr asked if i was on injections) folate 11.8 ug/L 3.1-19.9) vit d 54 mmol/L anything above 50 is adequate on spatone due to low ferritin
mandy72
in
Thyroid UK
5 years ago
Blood Sugar - Advice on weight and tummy reduction.
My wife is on either of insulin Apidra/Regular/Lispro 16 Units 15 to 30 minutes before B/F, lunch & dinner, Insulin Glargin 42 Units at 10pm, Vildagliptin 50 mg BD and Metformin 500 mg BD. She’s putting on weight (70kg, ht 160cm, age 68) & her tummy is coming out. HbA1C last was 7. Need advice on weight
My wife is on either of insulin Apidra/Regular/Lispro 16 Units 15 to 30 minutes before B/F, lunch & dinner, Insulin Glargin 42 Units at 10pm, Vildagliptin 50 mg BD and Metformin 500 mg BD. She’s putting on weight (70kg, ht 160cm, age 68) & her tummy is coming out. HbA1C last was 7. Need advice on weight
TRULYSPEAKING
in
Diabetes India
5 years ago
Pcos and ttc help advice?
Im 19 and have been diagnosed with Pcos for a year now, me and my partner are ttc and have been trying for around 6 months now. I am going to book a doctors appointment to look into getting clomid or metformin in order to help me ovulate. I was wondering if any ladies have any advice on any supplements
Im 19 and have been diagnosed with Pcos for a year now, me and my partner are ttc and have been trying for around 6 months now. I am going to book a doctors appointment to look into getting clomid or metformin in order to help me ovulate. I was wondering if any ladies have any advice on any supplements
Auraolse
in
PCOS UK (Verity)
5 years ago
Follow up appointment
Hi ladies hope everyone is doing well.. so I had my follow up appointment today as u all maybe have seen my previous post that I had failed cycle.. my consultant said to go for a short protocol and he gave me metformin and I have started taking it from today I will gradually increase it to 3 a day
Hi ladies hope everyone is doing well.. so I had my follow up appointment today as u all maybe have seen my previous post that I had failed cycle.. my consultant said to go for a short protocol and he gave me metformin and I have started taking it from today I will gradually increase it to 3 a day
Ourbaby1
in
Fertility Network UK
5 years ago
Success on Metformin?
Hi My first round of IVF has failed and my doctor has asked me to go on Metformin for 12 weeks. Has anyone had any success conceiving naturally on this? The side effects are proving difficult (I’m a sensitive flower sometimes) but determined to carry on taking them. Thanks xx
Hi My first round of IVF has failed and my doctor has asked me to go on Metformin for 12 weeks. Has anyone had any success conceiving naturally on this? The side effects are proving difficult (I’m a sensitive flower sometimes) but determined to carry on taking them. Thanks xx
Shinyhalo1
in
Fertility Network UK
5 years ago
Complex 1 inhibitors cause aggregation of a/syn and tau.
Getting rid of inhibitors gets rid of aggregates (What Nilotinib is supposed to do). A lot of (ordinary) things are inhibitors and they are adding to the list all the time: Examples: Aspirin Tetracycline, doxycycline, etc. Oxylates (spinach) Alcohol Beta blockers Some antidepressants Metformin
Getting rid of inhibitors gets rid of aggregates (What Nilotinib is supposed to do). A lot of (ordinary) things are inhibitors and they are adding to the list all the time: Examples: Aspirin Tetracycline, doxycycline, etc. Oxylates (spinach) Alcohol Beta blockers Some antidepressants Metformin
MBAnderson
in
Cure Parkinson's
5 years ago
Repurposing off label drugs for cancer/targeting metabolic pathways. Is anyone participating in this trial?
I expect I will get shot down in flames, but I have just read Jane McLelland’s ‘How to starve cancer’ (without starving yourself book) - she is a 15 year plus Stage IV cancer survivor. It’s very in-depth and well researched book (to my eyes anyway). There is a trial underway at the Care Clinic in Harley
I expect I will get shot down in flames, but I have just read Jane McLelland’s ‘How to starve cancer’ (without starving yourself book) - she is a 15 year plus Stage IV cancer survivor. It’s very in-depth and well researched book (to my eyes anyway). There is a trial underway at the Care Clinic in Harley
marya21
in
Advanced Prostate Cancer
5 years ago
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