I am a chronic diabetic for 30 years and have been taking Glynase mf morning 1 and night 1 and my sugar was almost under control.Recently I have been diagnosed as CKD 3rd stage and in spite of reducing salt and on kidney diet my creatinine level remains at 2.0 to 2.1 always.My nephrologist suggested to take istavel 50 mg morning 1 and night 1.but the sugar level is increasing very high and the Doctor told that though glynase mf controls sugar it will aggrevate kidney problem. What can I do.Already I had diabetic retinopathy and 15 lasers were done to both eyes and now eyes are OK I have a fear if due to intake of istavel if the BS increases my eye sight will be affected. I do not know which medicine to follow .Is it true that metformin increases kidney disease. I had my bypass surgery 25 years ago.I am taking BP tablet Amlong A one tablet in the morning.If I take glynase mf the reading will be fasting 90mg PP 150 to 160.If I take istavel 50 mg the reading will be fasting 160 and PP 230. What to do Kindly advise friends.For heart I am taking Ivarai kiran dil.Reg.heart now I am OK