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Bicalutamide or not?
Hello all! Quick summary: Diagnosed Nov. 2018, PSA 1036 (yes that's one THOUSAND thirty six!). Apparently only moved to lymph nodes(first thought bone mets-now looks like only voids in scan). Firmagon, then Lupron, then chemo, on going Lupron until Jan. 2020. Decided I'd try to quit the Lupron for a
Hello all! Quick summary: Diagnosed Nov. 2018, PSA 1036 (yes that's one THOUSAND thirty six!). Apparently only moved to lymph nodes(first thought bone mets-now looks like only voids in scan). Firmagon, then Lupron, then chemo, on going Lupron until Jan. 2020. Decided I'd try to quit the Lupron for a
Largell
in
Advanced Prostate Cancer
4 years ago
Unexplained Mid-Cycle Light-Mid Flow Bleeding - Can anyone help?
Hello All, Has anyone ever bled a medium flow for a few days mid cycle? I have spotted before/had a very light flow of blood, but usually, this is my 4th day that I have bled mid-cycle that isn’t a light bleed. It isn’t as heavy as having a period but I am needing to wear a panty liner and I would
Hello All, Has anyone ever bled a medium flow for a few days mid cycle? I have spotted before/had a very light flow of blood, but usually, this is my 4th day that I have bled mid-cycle that isn’t a light bleed. It isn’t as heavy as having a period but I am needing to wear a panty liner and I would
Ljayne
in
Fertility Network UK
4 years ago
Is facial swelling of concern
Hello, Wanted your help for my dad. He was diagnosed with metastatic pca with psa 114 and started on zytiga and prednisone. He is currently on zytiga 750 mg (due to higher liver Enzymes the mo lowered the dose from 1000 mg) and 5 mg of prednisone since the past couple of months, his last psa was undetectable
Hello, Wanted your help for my dad. He was diagnosed with metastatic pca with psa 114 and started on zytiga and prednisone. He is currently on zytiga 750 mg (due to higher liver Enzymes the mo lowered the dose from 1000 mg) and 5 mg of prednisone since the past couple of months, his last psa was undetectable
Life5
in
Advanced Prostate Cancer
4 years ago
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Fresh remyelination news
We are cured (again). A clinical trial of the cancer drug bexarotene showed that it repaired the protective myelin sheaths in Multiple Sclerosis patients. The drug had some serious side-effects, from thyroid disease to raised levels of fats in the blood, which can lead to dangerous inflammation of the
We are cured (again). A clinical trial of the cancer drug bexarotene showed that it repaired the protective myelin sheaths in Multiple Sclerosis patients. The drug had some serious side-effects, from thyroid disease to raised levels of fats in the blood, which can lead to dangerous inflammation of the
monkeybus
in
AMN EASIER
4 years ago
Probable 2nd reoccurrence of Prostate Ca. after DaVinci RP
Hi, I had Davinci R.P. in Feb 2014. Gleason 4+3. Margins clean. T2b. Salvage IMRT 40X Sept 2015. Psa undetectable since June 2019 @ .02, .03, .04, .03, .02 tested every 2-3 months. June 2020 undetectable. Sept 2020 psa .06. MSK recommended to wait till psa hits .05. I am retesting in 2-3 weeks to see
Hi, I had Davinci R.P. in Feb 2014. Gleason 4+3. Margins clean. T2b. Salvage IMRT 40X Sept 2015. Psa undetectable since June 2019 @ .02, .03, .04, .03, .02 tested every 2-3 months. June 2020 undetectable. Sept 2020 psa .06. MSK recommended to wait till psa hits .05. I am retesting in 2-3 weeks to see
rnewman751
in
Advanced Prostate Cancer
4 years ago
Are you taking Metformin? Be Alert for contamination with NDMA - A toxic substance which could cause Cancer- USFDA
If you are a Diabetic, in all possibilities you may be
taking Metformin. Please read the strip and see whether it is "extended release" or "Sustained release".
Then it may be possible that it may contain a toxic substance called nitrosodimethylamine (NDMA), a potential carcinogen generated
If you are a Diabetic, in all possibilities you may be
taking Metformin. Please read the strip and see whether it is "extended release" or "Sustained release".
Then it may be possible that it may contain a toxic substance called nitrosodimethylamine (NDMA), a potential carcinogen generated
namaha
Administrator
in
Diabetes India
4 years ago
I'm new...
hi everyone. im new to this and im not really sure how to go about this. i suffer from depression and anxiety (also being a hypochondriac) i also struggle with my physical health which im trying to work on as well. im currently on lexapro and lorazepam & for my physical health im on metformin. (idk too
hi everyone. im new to this and im not really sure how to go about this. i suffer from depression and anxiety (also being a hypochondriac) i also struggle with my physical health which im trying to work on as well. im currently on lexapro and lorazepam & for my physical health im on metformin. (idk too
gigimich
in
Anxiety and Depression Support
4 years ago
Merina coil concern
I am 22 years old and have been on the marina coil for a year and a half now. Recently I have being getting my periods and I'm worried because I havent been on for a full year. I have started taking metformin because I have pcos. Has any one else had this before? Is it normal? And this week I've started
I am 22 years old and have been on the marina coil for a year and a half now. Recently I have being getting my periods and I'm worried because I havent been on for a full year. I have started taking metformin because I have pcos. Has any one else had this before? Is it normal? And this week I've started
Unicorn_family
in
Women's Health
4 years ago
Side affects metformin
I have been taking metformin for about 6 months now, I have a lot of muscle/tendon pain and skin soreness. Is it a possible side affect?
I have been taking metformin for about 6 months now, I have a lot of muscle/tendon pain and skin soreness. Is it a possible side affect?
Lottybotty
in
Pain Concern
4 years ago
Metformin may delay PCa progression.
More from ESMO 2020: https://www.mdedge.com/hematology-oncology/article/228803/genitourinary-cancer/metformin-may-delay-prostate-cancer "Adding metformin to standard care for advanced prostate cancer appeared to lengthen time to castration-resistant disease in a small, randomized trial. “According to
More from ESMO 2020: https://www.mdedge.com/hematology-oncology/article/228803/genitourinary-cancer/metformin-may-delay-prostate-cancer "Adding metformin to standard care for advanced prostate cancer appeared to lengthen time to castration-resistant disease in a small, randomized trial. “According to
pjoshea13
in
Advanced Prostate Cancer
4 years ago
Metformin protective against PCa in diabetic patients.
New Canadian study (some US involvement) below [1]. "2,332 diabetic men were included, with a median follow-up time of 9.4 years (interquartile range 5.4-13.4 years). "A total of 2,036 patients (87.3%) received metformin. "Compared to non-metformin users, metformin use was associated with decreased
New Canadian study (some US involvement) below [1]. "2,332 diabetic men were included, with a median follow-up time of 9.4 years (interquartile range 5.4-13.4 years). "A total of 2,036 patients (87.3%) received metformin. "Compared to non-metformin users, metformin use was associated with decreased
pjoshea13
in
Advanced Prostate Cancer
4 years ago
My sugars
Hi all I bet you wondered where I was on Mondays weigh in well we took a few days away. I did weigh myself last Monday and I sts which I’m happy with. Whilst away have have got a skin infection on my arms and hands managed to see a doctor yesterday when we got home I’ve been given some cream with a
Hi all I bet you wondered where I was on Mondays weigh in well we took a few days away. I did weigh myself last Monday and I sts which I’m happy with. Whilst away have have got a skin infection on my arms and hands managed to see a doctor yesterday when we got home I’ve been given some cream with a
Hidden
8 stone
in
Weight Loss Support
4 years ago
Metformin: Preliminary Results of Trial in Advanced Prostate Cancer (MANSMED)
Not sure if this was posted here yet: In a mini-oral presentation at this year’s European Society of Medical Oncology (ESMO) 2020 Virtual Annual Meeting, Dr. Reham Alghandour presented the results of the MANSMED prospective randomized controlled trial. This trial recruited men with high risk localized
Not sure if this was posted here yet: In a mini-oral presentation at this year’s European Society of Medical Oncology (ESMO) 2020 Virtual Annual Meeting, Dr. Reham Alghandour presented the results of the MANSMED prospective randomized controlled trial. This trial recruited men with high risk localized
noahware
in
Advanced Prostate Cancer
4 years ago
Three common medications lower risk and mortality for lung cancer.
All three medications are common—approximately 35 million people take a statin to control cholesterol; more than 120 million people take metformin to control diabetes and between 6 and 10 million people take aspirin daily. The aim of this study was to investigate the associations of aspirin, metformin
All three medications are common—approximately 35 million people take a statin to control cholesterol; more than 120 million people take metformin to control diabetes and between 6 and 10 million people take aspirin daily. The aim of this study was to investigate the associations of aspirin, metformin
2greys
in
Lung Conditions Community Forum
4 years ago
How much is too much?
Hello everyone, I have taken Ropinirole since 1999 my doctor has increased my dose to 2mg 3 x daily over that time period It’s not enough medicine to sustain me between doses any more. I sleep one or two hours each night and take several hot baths to reduce the agony or pace all night long. My doctor
Hello everyone, I have taken Ropinirole since 1999 my doctor has increased my dose to 2mg 3 x daily over that time period It’s not enough medicine to sustain me between doses any more. I sleep one or two hours each night and take several hot baths to reduce the agony or pace all night long. My doctor
Moose68
in
Restless Legs Syndrome
4 years ago
Inflammation in the Liver Reversed by Metformin
Metformin is the First line drug for Type 2 Diabetes. It is in use for the last more than 50 years and there is hardly any adverse side effects if taken in recommended dosage. While a lot of research is still on to find out the exact mechanism of working , in the process science keeps finding out many
Metformin is the First line drug for Type 2 Diabetes. It is in use for the last more than 50 years and there is hardly any adverse side effects if taken in recommended dosage. While a lot of research is still on to find out the exact mechanism of working , in the process science keeps finding out many
namaha
Administrator
in
Diabetes India
4 years ago
Looking for IVF ICSI September cycle buddies!
Hello! This is my second cycle of IVF ICSI. We had our first on NHS two years ago. 15 eggs, 12 mature, 5 fertilised and had a freeze all as I bled into my pelvis after egg collection. Two thawed, one didn’t make it, so thawed another. Both slow to develop and failed FET. Second two thawed and also failed
Hello! This is my second cycle of IVF ICSI. We had our first on NHS two years ago. 15 eggs, 12 mature, 5 fertilised and had a freeze all as I bled into my pelvis after egg collection. Two thawed, one didn’t make it, so thawed another. Both slow to develop and failed FET. Second two thawed and also failed
lottiebeth84
in
Fertility Network UK
4 years ago
PART 1 : Reversing Memory Deficits And Senior Moments In A 78 Year Old
One issue with PD that is not discussed enough is memory issues and memory deficits as part of cognitive decline discussed briefly here: https://www.michaeljfox.org/news/memory-thinking-changes On that note I would like to discuss a very long time friend who has been having memory lapses and "senior
One issue with PD that is not discussed enough is memory issues and memory deficits as part of cognitive decline discussed briefly here: https://www.michaeljfox.org/news/memory-thinking-changes On that note I would like to discuss a very long time friend who has been having memory lapses and "senior
chartist
in
Cure Parkinson's
4 years ago
Has anyone seen this study from 2016?
https://onlinelibrary.wiley.com/doi/full/10.1111/jnc.13562 I contacted someone from the study; it appears it stopped after trials in mice. He replied that some people had contacted him, and are working with their doctor and this medication. Metformin is normally used as an anti-diabetic drug. I believe
https://onlinelibrary.wiley.com/doi/full/10.1111/jnc.13562 I contacted someone from the study; it appears it stopped after trials in mice. He replied that some people had contacted him, and are working with their doctor and this medication. Metformin is normally used as an anti-diabetic drug. I believe
bluejadedwho
in
AMN EASIER
4 years ago
Back trying for second IVF miracle 🤞🏻
Hi all I hope everyone is well reading this. I haven’t been on here properly for a while since we successfully got pregnant from ivf/icsi back in July 2017. Our little boy was born March 2018 and is now a very happy, healthy 2.5 yr old toddler! We felt ready to try again about 6 months after I had
Hi all I hope everyone is well reading this. I haven’t been on here properly for a while since we successfully got pregnant from ivf/icsi back in July 2017. Our little boy was born March 2018 and is now a very happy, healthy 2.5 yr old toddler! We felt ready to try again about 6 months after I had
Bluebelle1
in
Fertility Network UK
4 years ago
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